Search clinical trials for: Toripalimab in Combination With Platinum-based Chemotherapy

Total 610 results

Verastem, Inc.

Recruiting

Study of Avutometinib (VS-6766) +Defactinib With Gemcitabine and Nab-paclitaxel in Patients With Pancreatic Cancer (RAMP205)

Metastatic Cancer | Pancreas Cancer | Neoplasms Pancreatic | KRAS Activating Mutation | Malignant Neoplasm of Pancreas

United States
Pfizer

Terminated

Pre-Operative Study of PF-4691502 With Letrozole Compared To Letrozole Alone In Patients With Early Breast Cancer

Early Breast Cancer (Phase 2) | Advanced Breast Cancer (Phase 1b)

Spain, Sweden, Italy, Belgium
Xuejie Jiang

Recruiting

A Clinical Trail of Demethylation Drug Combined With Chemotherapy in Intermediate-risk AML

Leukemia, Myeloid

China
Hospital de Granollers

Completed

Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR) ((PROTOP-PAR))

Postoperative Hernia

Spain
Adaptimmune
ICON plc

Recruiting

ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)

Melanoma | Head and Neck Cancer | Esophageal Cancer | Ovarian Cancer | Endometrial Cancer | Urothelial Cancer | Gastric (Stomach) Cancer | Esophagogastric Junction (EGJ) | Non-small Cell Lung (NSCLC)

United States, Canada, Spain, Belgium
Boehringer Ingelheim

Completed

Assess Efficacy and Safety of the Dopamine Agonist Pramipexole Versus Levodopa / Benserazide (Madopar® DR) in Patients With Restless Legs Syndrome

Restless Legs Syndrome

Switzerland
Ye Xu

Unknown

Alternating Systemic and Hepatic Artery Infusion Therapy As Adjuvant Treatment After Resection of Liver Metastases From Colorectal Cancer

Resected Liver Metastases From Colorectal Cancer

China
University Medical Center Groningen
Radboud University Medical Center; Universitaire Ziekenhuizen KU Leuven; UMC... and other collaborators

Active, not recruiting

RCT Comparing Immunosuppressive Regimens in Elderly Renal Transplant Recipients (OPTIMIZE)

Elderly Patients | Immunosuppression | Renal Transplant Recipients

Netherlands, Belgium
Cairo University

Unknown

Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section

Pain

Egypt
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; National Institutes of Health (NIH)

Completed

Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma

Brain Cancer | Malignant Glioma

United States
Mario Negri Institute for Pharmacological Research
AstraZeneca; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Active, not recruiting

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC (BRIDGE)

Non-small Cell Lung Cancer Stage III

Italy, Spain, France
AstraZeneca

Active, not recruiting

Study of Durvalumab With Tremelimumab Versus SoC as 1st Line Therapy in Metastatic Non Small-Cell Lung Cancer (NSCLC) (NEPTUNE) (NEPTUNE)

Non Small Cell Lung Carcinoma NSCLC

Denmark, United Kingdom, United States, Poland, Brazil, India, Japan, Mexico, Peru, Russian Federation, Turkey, China, Malaysia, Hong Kong, Korea, Republic of, Chile, Israel, Ukraine, Portugal, Greece, Bulgaria, Philippines, Sweden, A... and more
AstraZeneca

Active, not recruiting

Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)

Non Small Cell Lung Carcinoma NSCLC

Poland, Taiwan, Thailand, Vietnam, United States, Korea, Republic of, Hungary, Russian Federation, Turkey, China, Australia, Netherlands
Boehringer Ingelheim

Completed

Evaluation of Efficacy and Tolerability of Micardis® / MicardisPlus® Under Usual Daily-practice Prescribing in Patients With Hypertension

Hypertension
Leiden University Medical Center
Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research

Unknown

Neurodevelopmental Outcome After Fetal Neonatal AlloImmune Thrombocytopenia (NOFNAIT)

Neurodevelopmental Abnormality | Fetal and Neonatal Alloimmune Thrombocytopenia | Long Term Adverse Effects | Intravenous Immunoglobulin Adverse Reaction

Netherlands
Threshold Pharmaceuticals

Unknown

Open-label Study of TH-302 and Dexamethasone With or Without Bortezomib or Pomalidomide in Subjects With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
The Second Affiliated Hospital of Kunming Medical...

Not yet recruiting

Comparison of the Efficacy and Safety of Venetoclax in Combination With 3 Days Decitabine (DEC3-VEN) vs. Venetoclax in Combination With Azacitidine (VIALE-A) in the Treatment of Elderly Patients or Unfit, New-diagnosis Acute Myeloid Leukemia Patients

Acute Myeloid Leukemia | Decitabine | Venetoclax | Elderly AML Patients | Unfit, New-diagnosis AML

China
University of Vermont
World Health Organization

Active, not recruiting

Intradermal Fractional Dose IPV (fIPV) in Combination With dmLT

Poliomyelitis

United States
Philogen S.p.A.

Terminated

Combination Therapy of L19IL2 and Gemcitabine in Advanced Pancreatic Cancer Patients

Pancreatic Cancer Patients Diagnosed With Locally Advanced or Metastatic Pancreatic Cancer Not Amenable to Curative Surgical Resection

Italy, Germany
Pfizer

Completed

Olmesartan Alone or in Combination With Hydrochlorothiazide in Subjects With Mild to Moderate Essential Hypertension (OSCAR)

Essential Hypertension

Colombia, Singapore, Taiwan, Thailand, Ecuador, Indonesia, Philippines, Hong Kong, Malaysia, Turkey
SOTIO a.s.

Completed

Phase II Study DCVAC/OvCa Plus Carboplatin Gemcitabine Relapsed Platinum (Pt)-Sensitive Epithelial Ovarian Carcinoma

Ovarian Neoplasms | Ovarian Epithelial Cancer | Ovarian Cancer (OvCa)

Czechia, Poland, Germany
Cedars-Sinai Medical Center

Completed

Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma

Glioma | Glioblastoma | Astrocytoma | Brain Tumor | Glioblastoma Multiforme

United States
Uman Pharma
DSM Nutritional Products, Inc.; MDEIE Ministry, Québec Government; INRS-Institut...

Completed

MTD Determination, Safety and Efficacy of the Decitabine-Genistein Drug Combination in Advanced Solid Tumors and Non-Small Cell Lung Cancer

Non Small Cell Lung Cancer

Canada
Italian Society of Cardiology
Federico II University; University Of Perugia; University of Messina; Azienda Ospedaliero-Universitaria... and other collaborators

Completed

Role of Sacubitril/Valsartan in the Improvement of Heart Failure With Reduced Ejection Fraction

Left Ventricular Dysfunction | Ventricular Remodeling | Heart Failure, Left Sided

Italy
Celldex Therapeutics

Completed

A Study of CDX-1401 in Patients With Malignancies Known to Express NY-ESO-1

Advanced Malignancies

United States
Ascenta Therapeutics
The Leukemia and Lymphoma Society

Terminated

Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Properties of Oral AT-406 in Combination With Daunorubicin and Cytarabine in Patients With Poor-risk Acute Myelogenous Leukemia (AML)

Acute Myelogenous Leukemia (AML)

United States
Merck Sharp & Dohme LLC

Completed

Suberoylanilide Hydroxamic Acid in Advanced Solid Tumors

Advanced Cancer
National Cancer Institute (NCI)

Recruiting

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States
Guangdong Provincial People's Hospital

Not yet recruiting

PCSK9 Inhibitors in Combination With Advanced Treatment Strategies for the Treatment of Advanced Colorectal Cancer With pMMR/MSS

Colorectal Cancer
Shandong Cancer Hospital and Institute

Unknown

Sorafenib Combined With Transarterial Chemoembolization in Treating HBV-infected Patients With Intermediate Hepatocellular Carcinoma

Liver Diseases | Neoplasms by Histologic Type | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Digestive System Neoplasms | Carcinoma, Hepatocellular | Liver Neoplasms | HBV | PHENYTOIN/SORAFENIB [VA Drug Interaction] | DOXORUBICIN/TRASTUZUMAB [VA Drug Interaction]

China
ArQule, Inc. (a wholly owned subsidiary of Merck...

Completed

ARQ 501 in Combination With Gemcitabine in Subjects With Pancreatic Cancer

Adenocarcinoma | Pancreatic Cancer

United States
Nantes University Hospital

Completed

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL) (Cloric)

AML | MDS | ALL | BAL

France
Eli Lilly and Company

Completed

Comparing 3 Schedules of Alimta Plus Gemzar

Neoplasms | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms

United States
London School of Hygiene and Tropical Medicine
University of California, Davis

Completed

Zinc Absorption From SQ-LNS With and Without Phytase

Individuals at Risk of Zinc Deficiency

Gambia
Peking University People's Hospital
The University of Science and Technology of China

Unknown

NK Cell Infusion for Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Adenocarcinoma | Lung Large Cell Carcinoma | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Minimally Invasive Lung Adenocarcinoma | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Lung Squamous Cell Carcinoma | Lung Adenosquamous Carcinoma

United States
University of Arkansas

Completed

Vaccination of Triple Negative Breast Cancer Patients

Breast Neoplasms | Triple Negative Breast Cancer

United States
Translational Research in Oncology
Bayer

Recruiting

Regorafenib-pembrolizumab vs. TACE/TARE in Intermediate Stage HCC Beyond Up-to-7 (REPLACE)

Carcinoma, Hepatocellular

Korea, Republic of, United States, Taiwan, Spain, Japan, France, Georgia, Belgium, Germany, Turkey, Italy, Hong Kong, Serbia
Institut Paoli-Calmettes
Novartis

Terminated

Dose Finding Study of BKM 120 in Combination With LH-RH Agonists and Bicalutamide in Men With Non Castrate Metastatic Prostate Cancer (NCMPC-BKM)

Non Castrate Metastatic Prostate Cancer

France
Lithuanian University of Health Sciences

Recruiting

Neoadjuvant Therapy vs Standard Therapy in Locally Advanced Rectal Cancer (RECTUM2015)

Neoadjuvant Therapy in Rectal Cancer, Radiotherapy, FOLFOX

Lithuania
Diako Ev. Diakonie-Krankenhaus gemeinnützige GmbH

Completed

Risk-stratified Sequential Treatment of Post-transplant Lymphoproliferative Disease (PTLD) With Rituximab SC and Immunochemotherapy (PTLD-2)

Posttransplant Lymphoproliferative Disorder

Germany
Sun Yat-sen University
Hainan General Hospital

Recruiting

Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma

Neuroblastoma

China
Janssen Biotech, Inc.

Active, not recruiting

IMAAGEN: Impact of Abiraterone Acetate in Prostate-Specific Antigen

Prostate Cancer | Prostatic Neoplasm

United States
University of Colorado, Denver
Pfizer; Criterium, Inc.; Cascadian Therapeutics Inc.

Completed

Tucatinib, Palbociclib and Letrozole in Metastatic Hormone Receptor Positive and HER2-positive Breast Cancer

Breast Cancer

United States
AstraZeneca

Active, not recruiting

Phase III Open Label First Line Therapy Study of MEDI 4736 (Durvalumab) With or Without Tremelimumab Versus SOC in Non Small-Cell Lung Cancer (NSCLC) (MYSTIC)

Non-Small-Cell Lung Carcinoma NSCLC

United States, Belgium, Spain, Canada, Taiwan, Thailand, Vietnam, France, Germany, Italy, Korea, Republic of, Hungary, Japan, Russian Federation, Netherlands, Australia, Switzerland
Kite, A Gilead Company

Active, not recruiting

Study of Effectiveness of Axicabtagene Ciloleucel Compared to Standard of Care Therapy in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma (ZUMA-7)

Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)

United States, Spain, United Kingdom, Canada, Netherlands, Germany, France, Sweden, Israel, Switzerland, Belgium, Australia, Austria, Italy
Barcelona Institute for Global Health
Centro de Investigação em Saúde de Manhiça; Medicines for Malaria Venture; University... and other collaborators

Recruiting

MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention (MULTIPLY)

Malaria

Sierra Leone, Mozambique, Togo
Hadassah Medical Organization

Unknown

Autologous Vaccination of Stage 4 Renal Cell Carcinoma Combined With Sunitinib (rcc)

Renal Cell Cancer
Immune System Key Ltd

Withdrawn

Safety and Efficacy of IV Nerofe™ Followed by Doxorubicin, In Metastatic Ovarian Cancer and Triple Negative Breast Cancer

Triple Negative Breast Cancer | Metastatic Ovarian Cancer

Israel
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Efficacy Mydrane ® for Cataract Surgery in Patients With Concomitant Primary Open Angle Glaucoma. (MIGA)

Cataract Surgery

Italy

Search clinical trials for: Toripalimab in Combination With Platinum-based Chemotherapy

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