Search clinical trials for: VTX-2337

Total 1933 results

Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del, Heterozygous for F508del and a Gating (F/G) or Residual Function (F/RF) Mutation, or Have At Least 1 Other Triple Combination Responsive (TCR) CFTR Mutation and No F508del Mutation

Cystic Fibrosis

United States, United Kingdom, Belgium, Netherlands, France, Denmark, Israel, New Zealand, Australia, Ireland, Sweden, Canada, Germany, Poland, Switzerland, Italy, Austria, Hungary, Greece, Norway
Gilead Sciences
Galapagos NV

Completed

Filgotinib Alone and in Combination With Methotrexate (MTX) in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Are Naive to MTX Therapy (FINCH 3)

Rheumatoid Arthritis

United States, Italy, Poland, Ukraine, Belgium, Hong Kong, Taiwan, Spain, Bulgaria, India, Malaysia, Romania, Serbia, South Africa, Korea, Republic of, Japan, Australia, Chile, Russian Federation, Argentina, Germany, New Zealand, Th... and more
Sanofi
PRA Health Sciences

Completed

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVaxTM-JE and JE-VAX

Japanese Encephalitis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508del and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, United Kingdom, New Zealand, Israel, Australia, Ireland, Germany, Sweden, Czechia, Portugal, Hungary
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-659 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Spain, Ireland, Australia, Israel, United Kingdom, Germany, Switzerland, Canada, Denmark, Poland
University of Sao Paulo General Hospital
Biosense Webster, Inc.

Completed

Efficacy and Safety of Epicardial VT Ablation Using Contact Force Irrigated Tip Catheter - Pilot Study

Tachycardia, Ventricular

Brazil
Hoffmann-La Roche

Completed

An Efficacy and Safety Study of Subcutaneous Tocilizumab in Combination With Methotrexate (MTX) and as Monotherapy Versus MTX in Participants With Moderate to Severe Rheumatoid Arthritis With Inadequate Response to Current Disease-Modifying Antirheumatic Drug (DMARD) Therapy

Rheumatoid Arthritis

China
Vertex Pharmaceuticals Incorporated

Terminated

A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy

Cystic Fibrosis

United States, Spain, Ireland, Australia, Israel, United Kingdom, Germany, Canada, Denmark, Poland, Switzerland
Kowa Company, Ltd.

Active, not recruiting

A Phase III Confirmatory Study of K-237

Covid19

Japan, Thailand
Vertex Pharmaceuticals Incorporated

Terminated

Evaluation of VX-659/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age

Cystic Fibrosis

United States
TransCode Therapeutics

Recruiting

A Microdose Study of TTX-MC138-NODAGA-Cu64 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

United States
Conjupro Biotherapeutics, Inc.
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

Dose Escalation and Dose Expansion Study of CPO-100 in Patients With Advanced Solid Tumors

Solid Tumor

United States
Codagenix, Inc

Active, not recruiting

Intramuscular CodaVax-H1N1 in Healthy Adults

Influenza, Human

Australia
University of Campania "Luigi Vanvitelli"

Completed

Diabetes and Lipid Accumulationand Heart Transplant (DCM-AHEAD)

Heart Failure | Diabetes Mellitus

Italy
University Hospital, Lille

Completed

Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness. (TIDALEC)

Hemodynamic Monitoring | Fluid Challenge

France
Baiya Phytopharm Co., Ltd.
National Vaccine Institute, Thailand

Completed

A Study to Evaluate Safety, Tolerability, and Reactogenicity of an RBD-Fc-based Vaccine to Prevent COVID-19

Coronavirus

Thailand
National Taiwan University Hospital

Completed

Comparison of PHVP of Different VTH Methods

Vault Prolapse, Vaginal
Inovio Pharmaceuticals

Completed

A Study of VGX-3100 DNA Vaccine With Electroporation in Patients With Cervical Intraepithelial Neoplasia Grade 2/3 or 3 (HPV-003)

Cervical Intraepithelial Neoplasia

South Africa, United States, Korea, Republic of, Canada, Estonia, India, Georgia, Australia, Puerto Rico
Sanofi

Completed

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAX

Japanese Encephalitis

Australia, United States
Lytix Biopharma AS

Completed

A Phase I/IIa Study to Evaluate the Safety, Tolerability and Efficacy of Topical LTX-109 in Subjects Nasally Colonized With Methicillin-resistant/-Sensitive Staphylococcus Aureus (MRSA/MSSA)

Nasal Carriers MRSA

Sweden
Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-445 Combination Therapy in CF Subjects Homozygous for F508del (F/F)

Cystic Fibrosis

United States, Belgium, Netherlands, United Kingdom
Chong Kun Dang Pharmaceutical

Completed

A Clinical Trial to Compare Safety and Pharmacokinetic Characteristics of CKD-337

Dyslipidemia
Avalo Therapeutics, Inc.

Terminated

Evaluation of the Safety, Tolerability, and Efficacy of MDGN-002 in Adults With Moderate to Severe Active Crohn's Disease or Ulcerative Colitis

Crohn Disease | Ulcerative Colitis

United States
University of Rochester
University of California, Los Angeles; Centers for Disease Control and Prevention

Active, not recruiting

Increasing Influenza and Tdap Vaccination of Pregnant Women

Pregnancy Related | Immunization; Infection

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Israel, Ireland, United Kingdom
Oncternal Therapeutics, Inc

Recruiting

A Clinical Study of ONCT-534 in Subjects With Metastatic Castration-resistant Prostate Cancer.

Metastatic Castration-resistant Prostate Cancer

United States, United Kingdom
W.L.Gore & Associates

Recruiting

Observational GORE® VIABAHN® Endoprosthesis With PROPATEN Bioactive Surface Global Registry

Trauma Injury | Peripheral Artery Disease | Hemodialysis Access | Popliteal Aneurysm | Visceral Artery Aneurysms

Spain, Italy, Germany, Sweden, Netherlands, United Kingdom, France, Belgium, Greece
TCM Biotech International Corp.

Recruiting

A Study of PTX-9908 Injection for Non-resectable HCC With TACE

Carcinoma, Hepatocellular

Taiwan
Neuraptive Therapeutics Inc.

Active, not recruiting

Safety and Efficacy of NTX-001 Compared to SOC in Acute Single Peripheral Nerve Injuries

Peripheral Nerve Injuries

United States
Ocular Therapeutix, Inc.

Completed

A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert

Open Angle Glaucoma and Ocular Hypertension

United States
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, is Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Evaluate Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Vaccine in Healthy Seronegative Adults Aged 18-64

Covid19 Vaccine

Canada
Steba Biotech S.A.
International Drug Development Institute; PrimeVigilance LTD

Terminated

Study of Erectile Dysfunction, Urinary Incontinence and Related QoL After TOOKAD® VTP for Low Risk Prostate Cancer

Low Risk Prostate Cancer

France
GTx

Terminated

Efficacy and Safety of GTx-024 in Patients With Androgen Receptor-Positive Triple Negative Breast Cancer (AR+ TNBC)

Triple Negative Breast Cancer

United States
Mansoura University

Not yet recruiting

Surgery for Primary Congenital Glaucoma in Neonates

Primary Congenital Glaucoma
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; Inovio Pharmaceuticals

Active, not recruiting

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Anal Intraepithelial Neoplasia | High Grade Squamous Intraepithelial Neoplasia | HIV Positivity | Human Papillomavirus-16 Positive | Human Papillomavirus-18 Positive

United States, Puerto Rico
Vanda Pharmaceuticals

Completed

Bioequivalence Study Between VHX-896 Tablets and Iloperidone Tablets in Healthy Volunteers

Healthy

United States
Guang'anmen Hospital of China Academy of Chinese...

Unknown

A Specification Clinical Application Research of Tripterygium Wilfordii Treating Rheumatoid Arthritis

Rheumatoid Arthritis

China
Abbott

Completed

Safety and Efficacy of Adalimumab to Methotrexate and Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis (CHAMPION)

Psoriasis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Belgium, Netherlands, United Kingdom, Canada, Germany, Australia, France, Italy, Czechia, Austria, Greece, Sweden
Palvella Therapeutics, Inc.

Recruiting

Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations

Microcystic Lymphatic Malformation

United States
Sorrento Therapeutics, Inc.

Completed

Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis

Osteoarthritis, Knee | Pain, Knee

United States
Merck Sharp & Dohme LLC
Integrated Therapeutics Group

Completed

Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422)

Arthritis, Psoriatic
Palvella Therapeutics, Inc.

Recruiting

A Study Evaluating the Safety and Pharmacokinetics of QTORIN Rapamycin 3.9% Anhydrous Gel in the Treatment of Adults With Pachyonychia Congenita

Pachyonychia Congenita

United States
Ruijin Hospital

Recruiting

Nab-PTX Plus S-1 and Sintilimab as Adjuvant Therapy in Patients With Stage IIIC Gastric Cancer

Stage IIIC Gastric Cancer

China
Vastra Gotaland Region

Recruiting

The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases (SOULMATE)

Colorectal Cancer | Liver Metastases | Colorectal Liver Metastases

Sweden
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Recruiting

Study of Safety & PK of Luspatercept (ACE-536) in Pediatric Participants With Beta (β)-Thalassemia

Beta-Thalassemia

United States, Turkey, Italy, Thailand, Germany, Greece, China, India, Lebanon
Botanix Pharmaceuticals

Completed

Evaluation of BTX 1503 in Patients With Moderate to Severe Acne Vulgaris

Acne Vulgaris

United States, Australia
Cook Group Incorporated

Completed

Zilver PTX Post-Market Study in Japan

Peripheral Arterial Disease (PAD)
AVAX Technologies

Terminated

DNP-Modified Autologous Tumor Cell Vaccine for Resectable Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer - Completely Resectable

United States
Cook Group Incorporated
William Cook Europe; MED Institute, Incorporated; Cook Japan Incorporated

Completed

Evaluation of the Zilver PTX Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery (Zilver PTX)

Peripheral Vascular Diseases

United States, Japan, Germany

Search clinical trials for: VTX-2337

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