Search clinical trials for: VX-147

Total 3931 results

Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Carcinoma in the Liver

United States
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
University of California, San Francisco
National Cancer Institute (NCI)

Terminated

Supportive Therapy in Androgen Deprivation Clinic in Improving Health Outcomes and Managing Side Effects in Patients With Prostate Cancer

Prostate Adenocarcinoma

United States
National Cancer Institute (NCI)

Completed

Androgen Deprivation Therapy and Vorinostat Followed by Radical Prostatectomy in Treating Patients With Localized Prostate Cancer (TARGET)

Prostate Adenocarcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Bristol-Myers Squibb

Completed

Dasatinib in Combination With Revlimid (and Dexamethasone)

Multiple Myeloma

United States, France, Australia
Far Eastern Memorial Hospital

Recruiting

HRT on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness

Menopausal Syndrome

Taiwan
Mansoura University

Not yet recruiting

Progestin-primed Ovarian Stimulation Protocol Versus GnRH Antagonist Protocol in Polycystic Ovary Syndrome Patients Undergoing IVF/ICSI Cycles

PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Poznan University of Medical Sciences
University at Buffalo; The Greater Poland Cancer Centre

Active, not recruiting

Translational PKPD Modeling of Anti-infective Drugs Used in Pediatric Units.

Population Modeling of Anti-infective Drugs

Poland
South Plains Oncology Consortium
The Evan Foundation

Terminated

Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastoma (SPOC2013-001)

Neuroblastoma | Recurrent Neuroblastoma

United States
Bayer

Completed

Study to Find Out if Cream V61-044 Used to Treat Fungal Infections Causes an Allergic Skin Reaction to Sunlight in Healthy Participants

Dermatitis, Photoallergic

United States
Parc de Salut Mar

Completed

Steroid Profile: Differentiating Testosterone Administration From (Simultaneous) Ethanol Consumption (SPOL1)

Healthy Volunteers

Spain
Corcept Therapeutics

Completed

Mifepristone Drug-Drug Interaction Study With CYP3A Inhibitor

Healthy | Drug Interaction Potentiation

United States
GlaxoSmithKline

Completed

A Study to Assess the Safety and Interaction Between Casopitant and Ketoconazole When Taken By Healthy Adults

Nausea and Vomiting, Chemotherapy-Induced

United States
Bristol-Myers Squibb

Completed

Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986141 in Healthy Subjects

Thrombosis

United States
Pfizer

Completed

A Study to Estimate the Effect of CYP3A4 Inhibitors (Itraconazole, Diltiazem or Verapamil) on the Pharmacokinetics of Single Dose PF- 00489791 in Healthy Volunteers

Healthy Volunteers

Belgium
Medical University of Vienna

Terminated

Perioperative Fluid Management in Patients Receiving Major Abdominal Surgery - Effects of Normal Saline Versus an Acetate Buffered Balanced Infusion Solution on the Necessity of Catecholamines for Cardiocirculatory Support (KATECHOL)

Critical Illness

Austria
Indiana University
National Institutes of Health (NIH); National Institute of General Medical...

Completed

Determine the Effects of Gene Differences and Voriconazole on Enzyme CYP2B6 Activity in the Liver in Healthy Volunteers

Efavirenz, Metabolism and Pharmacokinetics Changes

United States
Boehringer Ingelheim

Completed

Effects of Single-dose and Steady-state TPV/RTV on the Steady-state Pharmacokinetics of Fluconazole in Healthy Adult Volunteers

Healthy
Shanghai Jiao Tong University School of Medicine

Completed

Efficiency Study of Clarithromycin and Bismuth-containing Quadruple Therapy to Treat H.Pylori

Functional Dyspepsia | Peptic Ulcer | Helicobacter Pylori

China
University Hospital, Grenoble

Completed

Role of Epoxy-eicosatrienoic Acids in Post-occlusive Hyperemia and Thermal Hyperemia (EETY)

Healthy Volunteers

France
Turku University Hospital

Completed

Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol

Pharmacokinetics | Pharmacodynamics

Finland
Zodiac Produtos Farmaceuticos S.A.

Unknown

Evaluate Efficacy, Tolerability & Safety of Combination of Clindamycin and Ketoconazole for the Treatment of Mixed-Type Vaginosis, Bacterial Vaginosis and Candidiasis

Candidiasis | Bacterial Vaginosis

Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Unresectable Pancreatic Carcinoma

United States
University of Illinois at Chicago
National Institute of Mental Health (NIMH)

Completed

Research Investigation of Soy and Estrogen (RISE)

Hot Flashes | Menopause

United States
National Cancer Institute (NCI)
Gynecologic Oncology Group

Completed

Thalidomide in Treating Patients With Recurrent or Persistent Carcinosarcoma of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Carcinosarcoma

United States
The University of Texas Health Science Center,...

Terminated

Hormonal Therapy and Chemotherapy Followed by Prostatectomy in Patients With Prostate Cancer

Prostate Cancer

United States
University of Washington
GlaxoSmithKline; AstraZeneca

Completed

Maximal Suppression of the Androgen Axis in Clinically Localized Prostate Cancer (TAPS)

Cancer | Prostate Neoplasms

United States
Sahlgren´s University Hospital
Sahlgrenska University Hospital, Sweden

Withdrawn

Pain as Indication for Operative Treatment of Traumatic Rib Fractures (potf)

Pain | Trauma | Surgery | Rib Fractures

Sweden
MEDRx USA, Inc.

Completed

Etodolac-Lidocaine Patch in the Treatment of Acute Low Back Pain

Low Back Pain

United States
Pierre Fabre Dermo Cosmetique
Quanta Medical

Unknown

Efficacy, Safety and Cost-effectiveness of a Sequential Therapy With RV4104A Ointment, Ciclopiroxolamine Cream and Ciclopirox Film-forming Solution Compared With Amorolfine Nail Lacquer in Dermatophytic Onychomycosis (ONICO)

Onychomycosis

France
Université de Sherbrooke
Canadian International Development Agency

Completed

Study of the Management of Vaginal Discharge in West African Using Single Dose Treatments

Candidiasis | Vaginitis | Bacterial Vaginosis

Ghana, Guinea, Togo
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a Quadriphasic Contraceptive Pills, 1 - 3 mg Estradiol Valerate/ 2 - 3 mg Dienogest VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
Sohag University

Not yet recruiting

Pack Cross Linking for Infectious Keratitis

Infectoius Keratitis

Egypt
Radboud University Medical Center

Not yet recruiting

The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery (REMEDI)

Coronary Artery Disease | Systemic Inflammatory Response Syndrome | Extracorporeal Circulation; Complications | Postoperative Shock

Netherlands
Memorial Sloan Kettering Cancer Center

Withdrawn

A Study of 1 8F-FDHT PET/MRIScans in Women With Breast Cancer

Breast Cancer | Metastatic Breast Cancer | Breast Carcinoma | Metastatic Breast Carcinoma | Female Breast Cancer
Azidus Brasil

Suspended

Efficacy and Comparative of the Association Beclomethasone Clotrimzaol + Gentamicin in Patients With Acne Contaminated (acne)

Folliculitis

Brazil
Hams Hamed Abdelrahman

Unknown

Vitamin D Oral Gel for Prevention of Radiation Induced Oral Mucositis

Oral Mucositis Due to Radiation

Egypt
Astellas Pharma Global Development, Inc.

Completed

Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Germany, Italy
Dow University of Health Sciences

Completed

Comparison of Antibacterial Efficacy of Three Final Irrigants

Endodontic Disease | Root Canal Infection

Pakistan
The University of Texas Health Science Center,...

Terminated

Hormone Therapy Plus Chemotherapy as Initial Treatment for Local Failures or Advanced Prostate Cancer

Prostatic Neoplasms

United States
International Partnership for Microbicides, Inc.

Completed

To Assess the Drug-drug Interaction Potential Between Dapivirine Vaginal Ring-004, Containing 25 mg of Dapivirine, and Clotrimazole 10 mg/g (1%)

HIV- Prevention
Johns Hopkins University
National Institute of Mental Health (NIMH)

Completed

Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder (ParaFlu)

HIV Associated Neurocognitive Disorder

United States
Farabi Eye Hospital

Unknown

UVX as an Adjuvant in the Treatment of Fungal Keratitis

Treatment
Aravind Eye Care System

Unknown

Clinical & Visual Outcomes of Collagen Cross Linking for Fungal Keratitis

Mycotic Corneal Ulcer

India
Technische Universität Dresden

Completed

Comparison of Skin Thickness Under Treatment With Pimecrolimus 1% Cream, Hydrocortisonacetat 1% Cream, Betamethasonvalerat 0,1% Cream and Clobetasol-17-propionat 0,05% Cream Assessed by Optical Coherence Tomography (OCT) and 20-MHZ Ultrasound (OCT)

Healthy

Germany
Instituto Valenciano de Infertilidad, IVI VALENCIA

Unknown

Comparison Between Natural and Artificial Cycle in Recipient Oocyte Patients

Infertility

Spain
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Bayesian Basket Trial (PALETTE)

Sepsis
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth (AUTOP2)

Bacterial Vaginosis | Premature Delivery | Vaginal Dysbiosis
TYK Medicines, Inc

Recruiting

Studies Evaluating the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of TY-9591 Tablets in Healthy Subjects

NSCLC

China

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