Search clinical trials for: VX-985 or matching placebo

Total 1984 results

Zynerba Pharmaceuticals, Inc.

Completed

Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX) (CONNECT-FX)

Fragile X Syndrome

United States, New Zealand, Australia
Blueprint Medicines Corporation

Active, not recruiting

(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis

Indolent Systemic Mastocytosis

Canada, United States, Spain, United Kingdom, Germany, Belgium, Switzerland, Italy, Netherlands, Denmark, France, Norway, Sweden
Theravance Biopharma

Terminated

Phase 3 Clinical Effect Durability of TD-9855 for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure (REDWOOD)

Parkinson's Disease (PD) | MSA | Symptomatic Neurogenic Orthostatic Hypotension | Pure Autonomic Failure (PAF)

United States, Spain, United Kingdom, Canada, France, Estonia, Australia, Israel, Denmark, Italy, Poland, New Zealand, Germany, Ukraine, Austria, Bulgaria, Portugal, Hungary, Russian Federation
Xinnate AB
Region Skane

Completed

Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.

Blister | Epidermolysis Bullosa | Wound of Skin | Varicose Ulcer of Lower Limb

Sweden
Boehringer Ingelheim

Recruiting

A Study to Test Whether Spesolimab Helps People With a Skin Disease Called Netherton Syndrome

Netherton Syndrome

Belgium, United Kingdom, Australia, Germany, China, Malaysia, Japan, France, United States, Israel, Bulgaria, Italy, Switzerland, Austria, Netherlands, Portugal
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

Safety and Efficacy of Telaprevir in Combination With Peginterferon Alfa-2a and Ribavirin in Subjects Co-Infected With Hepatitis C Virus (HCV) and HIV

HIV Infections | Hepatitis C

France, Spain, United States, Germany
Regeneron Pharmaceuticals
Sanofi

Completed

Dupilumab As An Adjunct For Subcutaneous Grass Immunotherapy

Allergic Rhinitis

United States, Canada
University of Cincinnati

Active, not recruiting

Early Intervention in Cognitive Aging

Overweight, Obesity and Other Hyperalimentation (E65-E68)

United States
Children's Hospital of Philadelphia

Completed

Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome (TRIO)

Obstructive Sleep Apnea Syndrome | Down Syndrome

United States
Grand Medical Pty Ltd.
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Effect of STC314 Injection Continuous Infusion in Subjects With Acute Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

China
Vertex Pharmaceuticals Incorporated

Terminated

A Study to Evaluate Efficacy and Safety of Ivacaftor in Subjects With Cystic Fibrosis Aged 3 Through 5 Years Who Have a Specified CFTR Gating Mutation

Cystic Fibrosis

United Kingdom, Canada, Australia
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Subjects With Cystic Fibrosis (CF) Who Have the R117H-CF Transmembrane Conductance Regulator (CFTR) Mutation (KONDUCT) (KONDUCT)

Cystic Fibrosis

United States, United Kingdom
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older With the G551D Mutation (STRIVE)

Cystic Fibrosis

United States, Canada, Australia, Ireland, France, United Kingdom, Germany, Czech Republic
Vertex Pharmaceuticals Incorporated
Cystic Fibrosis Foundation

Completed

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 6 to 11 Years With the G551D Mutation (ENVISION)

Cystic Fibrosis

United States, Australia, Canada, France, Germany, Ireland, United Kingdom
Unity Health Toronto
Canadian Institutes of Health Research (CIHR); Canadian Foundation for AIDS... and other collaborators

Recruiting

Our Healthbox - Evaluating Interactive Dispensing Systems for Low-Barrier Access to HIV Testing and Harm Reduction.

Blood-Borne Infections | Sexually Transmitted Diseases | HIV | Harm Reduction | HIV Self-testing

Canada
H. Lundbeck A/S

Completed

Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AE58054 in Healthy Japanese and Caucasian Subjects

Healthy

United Kingdom
Armgo Pharma, Inc.
Food and Drug Administration (FDA)

Recruiting

Treatment of an Inherited Ventricular Arrhythmia

Catecholaminergic Polymorphic Ventricular Tachycardia Type 1

United States, Netherlands
Bacainn Therapeutics, Inc.

Completed

A Phase 1, Single-Ascending-Dose Study of BT051 in Healthy Subjects

Healthy Volunteers

United States
Nestlé

Completed

Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of CDX-6114 in Patients With Phenylketonuria (PKU)

Phenylketonuria

Australia, Germany
Merit E. Cudkowicz, MD
Calico Life Sciences LLC

Enrolling by invitation

HEALEY ALS Platform Trial - Regimen F ABBV-CLS-7262

Amyotrophic Lateral Sclerosis

United States
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V116 When Administered Concomitantly With Influenza Vaccine in Adults 50 Years of Age or Older (V116-005, STRIDE-5)

Pneumonia, Pneumococcal

United States
GlaxoSmithKline

Terminated

Efficacy and Safety Study of Mepolizumab in Subjects With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

United States, Canada
Vaxart

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of Twice Daily Topical Applications of AP611074 5% Gel for up to 16 Weeks in Condyloma Patients

Condyloma

Argentina, Chile, Ecuador, Serbia
GlaxoSmithKline

Completed

A Study of GSK573719 in Healthy Japanese Male Subjects

Pulmonary Disease, Chronic Obstructive

Japan
Respivert Ltd

Completed

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Repeat Doses of RV1729 for 28 Days in Patients With COPD

Chronic Obstructive Pulmonary Disease

United Kingdom
Drugs for Neglected Diseases
Bayer

Active, not recruiting

Emodepside Phase II Trial for Treatment of Onchocerciasis

Onchocerciasis

Ghana, Congo, The Democratic Republic of the
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and Pharmacodynamic Study of ISIS CRP Rx in Rheumatoid Arthritis

Rheumatoid Arthritis

Canada, Russian Federation
University of South Florida

Completed

Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients (DUSTMITE)

ALLERGIC RHINITIS

United States
University Hospital, Ghent

Completed

A Trial Investigating the Effect of a Treatment With Zinkgluconaat for Verrucae Vulgares

Verrucae Vulgares

Belgium
Kowa Company, Ltd.

Recruiting

A Phase 3 Study to Evaluate the Efficacy and Safety of K-877 in Chinese Patients With High TG and Low HDL-C

Hyperlipidemia

China
Dompé Farmaceutici S.p.A

Terminated

Ascending Dose Tolerability Trial and PK Assessment in Healthy Volunteers After Single & Multiple Oral Intake of DF2755A

no Condition

France
Conatus Pharmaceuticals Inc.

Unknown

Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis (ENCORE-LF)

Decompensated Cirrhosis

United States
HeNan Sincere Biotech Co., Ltd

Completed

A Study of CL-197 Capsules in Healthy Participants

HIV-1

China
Shanghai Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE SUBCUTANEOUS INJECTIONS OF SHR-1819 IN PATIENTS WITH MODERATE TO SEVERE ATOPIC DERMATITIS

Moderate to Severe Atopic Dermatitis
Guangdong Hengrui Pharmaceutical Co., Ltd

Enrolling by invitation

Safety and Tolerance of Increased Doses of SHR-2106 Injection in Healthy Subjects

Kidney Transplantation

China
University Hospital, Bonn

Active, not recruiting

An Exploratory Clinical Study on Autophagy and Multi-level Molecular Profiling During Spermidine Supplementation

Depression | Healthy

Germany
Neurogen Corporation

Terminated

Efficacy and Safety Study of Aplindore in Patients With Early Parkinson Disease

Early Parkinson Disease

United States
Shandong Suncadia Medicine Co., Ltd.

Active, not recruiting

Safety and Tolerance of Increased Doses of HRS-1780 Tablets in Healthy Subjects

Chronic Kidney Disease

China
Bridge Biotherapeutics, Inc.
Covance

Completed

Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis

Ulcerative Colitis

United States, Korea, Republic of, Poland, Ukraine
7TM Pharma A/S

Terminated

A Study to Determine the Effects of TM30339 on Weight Loss in Obese Individuals.

Obesity
Neurogen Corporation

Terminated

Efficacy and Safety Study of Aplindore in Patients With Restless Legs Syndrome

Restless Legs Syndrome

United States
University Hospital, Strasbourg, France

Unknown

Arteriopathy and Endothelial Function

Peripheral Arterial Disease

France
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of K-757 in Healthy Overweight/Obese Volunteers

Obesity

United States
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty

Acute Pain

United States
Evolve BioSystems, Inc.

Terminated

The COLIC Study: Colonization of the Infant Gut With B. Infantis EVC001 to Reduce Symptoms of Colic (COLIC)

Infantile Colic

United States
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Not yet recruiting

Safety, Tolerability, and Biosignature of Humanized Prebiotics in Healthy Adults

Intestinal Health

United States
The University of Hong Kong
Immuno Cure 3 Limited

Recruiting

A Study to Evaluate Safety & Immunogenicity of SARS-CoV-2 DNA Vaccine Delivered Intramuscularly Followed by Electroporation for COVID-19

Covid19

Hong Kong
CuraSen Therapeutics, Inc.

Not yet recruiting

A Study of CST-103 Co-administered With CST-107 in Subjects With Parkinson's Disease Having Freezing of Gait (CLIN-012)

Freezing of Gait Symptoms in Parkinson's Disease

Australia
Redx Pharma Plc
Simbec Research

Completed

A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy Volunteers

Liver Diseases | Fibrosis | Kidney Diseases | Inflammation | Idiopathic Pulmonary Fibrosis | Non-alcoholic Steatohepatitis

United Kingdom
Kallyope Inc.

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of K-757 and K-833 in Overweight/Obese Patients With Type 2 Diabetes

Obesity | Type 2 Diabetes Mellitus in Obese

United States

Search clinical trials for: VX-985 or matching placebo

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