Search clinical trials for: Vincristine, Irinotecan

Total 2425 results

Centre Oscar Lambret
SFCE

Completed

Vincristine and Irinotecan With or Without Temozolomide in Children and Adults With Refractory/Relapsed Rhabdomyosarcoma (VIT-0910)

RHABDOMYOSARCOMA

France
Bayer

Completed

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Pediatric Oncology

United Kingdom, France, Spain, Italy
Joel Neal
Nektar Therapeutics

Completed

Phase 2 Etirinotecan Pegol in Refractory Brain Metastases & Advanced Lung Cancer / Metastatic Breast Cancer

Tumors Metastatic to Brain | Stage IV Non-small Cell Lung Cancer (NSCLC) | Recurrent Non-small Cell Lung Cancer (NSCLC) | Extensive-stage Small Cell Lung Cancer (SCLC) | Recurrent Small Cell Lung Cancer (SCLC) | Metastatic Breast Cancer (mBC)

United States
Nektar Therapeutics

Completed

NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer

Colorectal Cancer

United States, Belgium, Germany, India, Spain, United Kingdom
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma

Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Childhood Solid Tumor, Protocol Specific

United States, Australia
Sun Yat-sen University
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Doxorubicin Hydrochloride Liposome Combined With Irinotecan Versus VIT Regimen in the Treatment of Pediatric Rhabdomyosarcoma

Rhabdomyosarcoma, Child
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors

Canada, United States
Alchemia Oncology

Unknown

Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC (FOLF(HA)iri)

Metastatic Colorectal Cancer

Australia
Abramson Cancer Center of the University of Pennsylvania

Completed

Etirinotecan Pegol (NKTR-102) in NSCLC

Metastatic Non Small Cell Lung Cancer | Recurrent Non Small Cell Lung Cancer

United States
St. Jude Children's Research Hospital
AstraZeneca; National Institutes of Health (NIH)

Completed

Study of ZD1839 Combined With Irinotecan and Vincristine in Pediatric Patients With Refractory Solid Tumors

Solid Tumors

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma

Sarcoma, Ewing

China
University of Regensburg

Completed

Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults (NOA-07)

Medulloblastoma

Germany
University of Texas Southwestern Medical Center

Recruiting

VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

Solid Tumor | Rhabdomyosarcoma

United States
Acrotech Biopharma Inc.
National Cancer Institute (NCI)

Completed

To Evaluate the Safety, Activity and Pharmacokinetics of Marqibo in Children and Adolescents With Refractory Cancer

Sarcoma | Lymphoma | Leukemia | Neuroblastoma | Brain Tumors | Wilms Tumor

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI); Spectrum Pharmaceuticals, Inc

Terminated

Vincristine Sulfate Liposome in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia

United States
Hallym University Medical Center
Jeil Pharmaceutical Co., Ltd.

Unknown

Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract Cancer

Biliary Tract Neoplasm

Korea, Republic of
Hallym University Medical Center
Jeil Pharmaceutical Co., Ltd.

Completed

Study of Oxaliplatin, Irinotecan, and S-1 in Gastric Cancer

Stomach Neoplasm

Korea, Republic of
ECOG-ACRIN Cancer Research Group

Recruiting

Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia

Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | T Acute Lymphoblastic Leukemia | Lymphoblasts 5 Percent or More of Bone Marrow Nucleated Cells

United States
Nektar Therapeutics

Completed

NKTR-102 in Combination With Cetuximab in Patients With Refractory Solid Tumors (Phase 2a) and Metastatic or Locally Advanced Colorectal Cancer (Phase 2b)

Colorectal Cancer | Tumor

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Sarcoma

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Shanghai Zhangjiang Biotechnology Limited Company
Shanghai Biomabs Pharmaceutical Co., Ltd.

Completed

Study of CMAB009 to Treat KRAS Wild Type Metastatic Colorectal Cancer (CRC009)

Metastatic Colorectal Cancer
ShengFa Su

Unknown

Irinotecan Plus Lobaplatin Versus Irinotecan in the Second-line Treatment of Small Cell Lung Cancer

Small-cell Lung Cancer

China
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Vincristine Pharmacokinetics in Infants

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States, Australia, Canada
M.D. Anderson Cancer Center
Inex Pharmaceuticals

Completed

Liposomal Vincristine for Pediatric and Adolescent Patients With Relapsed Malignancies

Soft Tissue Sarcoma | Lymphoma | Leukemia | Osteosarcoma | Wilms' Tumor

United States
Nanjing Luye Sike Pharmaceutical Co., Ltd.
China Medical University, China; Xijing Hospital; The Second Hospital of Hebei... and other collaborators

Unknown

Phase III Study of Vincristine Sulfate Liposome For Injection In Adults With Naïve Acute Lymphoblastic Leukemia (LY01609)

Adult Acute Lymphoblastic Leukemia

China
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

Glioma | Astrocytoma | Oligodendroglioma

United States
Nelson Yee
Ipsen

Active, not recruiting

Liposomal Irinotecan in Combination With Oxaliplatin, Leucovorin, and 5-fluorouracil for Patients With Locally Advanced Pancreatic Carcinoma:

Locally Advanced Pancreatic Carcinoma(LAPC)

United States
Spectrum Pharmaceuticals, Inc
Parexel

Completed

Safety and Efficacy of Marqibo in Relapsed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL)

United States, Canada, Germany, Israel, United Kingdom
Boston Scientific Corporation
Biocompatibles UK Ltd

Completed

Study of Chemoembolisation Using Irinotecan Bead Prior to Surgery in Metastatic Colorectal Cancer (PARAGON-II)

Metastatic Colorectal Cancer

United Kingdom, Austria, France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma

Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Vincristine, Carboplatin, and Etoposide or Observation Only in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Retinoblastoma

Intraocular Retinoblastoma

United States, Canada, Australia, New Zealand, India
Baohui Han

Not yet recruiting

Safety and Efficacy of Adebrelimab Plus Irinotecan Liposome (II) With or Without Famitinib in ES-SCLC Pre-treated With Immunotherapy

Extensive-stage Small-cell Lung Cancer

China
National Cancer Institute (NCI)

Completed

Genetic Testing Plus Irinotecan in Treating Patients With Solid Tumors or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Japan Clinical Cancer Research Organization
Taiho Pharmaceutical Co., Ltd.

Completed

Second Line Chemotherapy for S-1 Refractory Advanced Gastric Cancer

Gastric Cancer

Japan
Fudan University

Not yet recruiting

Irinotecan Liposome Combined With Anlotinib as Second-line Regimen for SCLC

Small Cell Lung Cancer Recurrent

China
National Cancer Institute (NCI)

Active, not recruiting

Liposomal Irinotecan and Veliparib in Treating Patients With Solid Tumors

Malignant Solid Neoplasm

United States
Dong-A University Hospital
Pusan National University Yangsan Hospital

Completed

FOLFOX Followed by FOLFIRI or Reverse Sequence Treatment in Advanced Gastric Cancer (AGC)

Gastric Cancer

Korea, Republic of
Bristol-Myers Squibb

Completed

A Phase II Study of Carboplatin Plus Irinotecan Versus Irinotecan in Children With Refractory Solid Tumors

Neoplasms

United States
University of California, Irvine

Withdrawn

A Pilot Study of Irinotecan in Patients With Breast Cancer and CNS Metastases

Male Breast Cancer | Stage IV Breast Cancer | Recurrent Breast Cancer | Central Nervous System Metastases
Spectrum Pharmaceuticals, Inc

Terminated

A Phase 3 Study to Evaluate Marqibo® in the Treatment of Subjects ≥ 60 Years Old With Newly Diagnosed ALL

Acute Lymphoblastic Leukemia (ALL)

United States
Fundació Institut de Recerca de l'Hospital de la...

Unknown

Study to Evaluate the Efficacy and Safety of FOLFIRI-AD in Patients With Metastatic Colorectal Cancer UGT1A Genotype 1 (FOLFIRI-AD)

Metastatic Colorectal Cancer

Spain
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Children With Refractory Solid Tumors

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Ewing Sarcoma/Peripheral... and other conditions

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Nektar Therapeutics

Completed

Pegylated Irinotecan NKTR 102 in Treating Patients With Relapsed Small Cell Lung Cancer

Recurrent Small Cell Lung Carcinoma

United States
Swiss Group for Clinical Cancer Research

Completed

Combination Chemotherapy in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Switzerland
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors (NEXIRI2)

Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors

France
Dutch Colorectal Cancer Group
Sanofi; Hoffmann-La Roche; Koningin Wilhelmina Fonds

Completed

Sequential Versus Combination Chemotherapy in Advanced Colorectal Carcinoma

Advanced Colorectal Cancer
Sabine Mueller, MD, PhD
Pacific Pediatric Neuro-Oncology Consortium; The V Foundation for Cancer Research

Completed

CED With Irinotecan Liposome Injection Using Real Time Imaging in Children With Diffuse Intrinsic Pontine Glioma (DIPG) (PNOC 009)

Diffuse Intrinsic Pontine Glioma

United States
Advocate Health Care

Withdrawn

Evaluation of Low-dose Irinotecan and Cyberknife® SBRT to Treat Colorectal Cancer With Limited Liver Metastasis

Colorectal Cancer

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States

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