Search clinical trials for: Viral Protease Inhibitors

Total 64417 results

American Society of Hematology

Active, not recruiting

The American Society of Hematology (ASH) Research Registry: A Multicenter Research Registry of Patients With Hematologic Disease

Benign and Malignant Hematologic Diseases

United States
National Institute of Dental and Craniofacial Research...

Completed

Effects of Topical SLPI on Skin Wounds

Healthy | Wound Healing

United States
University of Florence
Azienda Ospedaliero-Universitaria Careggi; Istituto per lo Studio, la Prevenzione...

Recruiting

SLPI for Prostate Cancer

Prostate Cancer | Prostatic Neoplasm

Italy
Boehringer Ingelheim

Completed

Dose Ranging Trial of Tipranavir/Ritonavir in Treatment-Experienced HIV Infected Individuals

HIV Infections

United States, Puerto Rico
Medical Research Council
NHS Health Technology Assessment Programme

Unknown

Protease Inhibitor Monotherapy Versus Ongoing Triple-therapy in the Long Term Management of HIV Infection (PIVOT) (PIVOT)

Acquired Immunodeficiency Syndrome | HIV Infection
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Strategies and Treatments for Respiratory Infections & Viral Emergencies (STRIVE): Shionogi Protease Inhibitor (Ensitrelvir)

COVID-19

United States, Singapore, Japan, Ukraine, Georgia, Korea, Republic of, Australia, Denmark, Thailand, Greece, South Africa, Germany, Uganda, Spain, Puerto Rico, Argentina
GlaxoSmithKline

Completed

Study To Evaluate Long Term Maintenance With TRIZIVIR After Boosted Protease Inhibitor (PI) Or Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) In HIV-1 Infected Adults

HIV Infections
Janssen R&D Ireland

Completed

Study to Evaluate Efficacy and Safety of Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Regimen Versus Boosted Protease Inhibitor (bPI) Along With Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) Regimen in Virologically-Suppressed, HIV-1 Infected Participants

Human Immunodeficiency Virus Type 1

United States, France, United Kingdom, Belgium, Spain, Switzerland, Sweden, Canada, Puerto Rico, Poland
Cytonics Corporation
Southern Star Research Pty Ltd.

Not yet recruiting

Evaluation of CYT-108, a Recombinant Protease Inhibitor, for Treatment of Mild to Moderate Primary Osteoarthritis of the Knee

Osteoarthritis | Osteoarthritis, Knee

Australia
Tibotec Pharmaceuticals, Ireland

Completed

A Study With TMC125 in Human Immunodeficiency Virus (HIV) Type 1 Infected Patients, Who Were Treated With TMC125 Arm in a Sponsor-Selected TMC125 Study

Human Immunodeficiency Virus Type 1
ViiV Healthcare
GlaxoSmithKline

Completed

Pharmacodynamics, Safety and Pharmacokinetics of BMS-663068, an HIV Attachment Inhibitor, in HIV-1

HIV Infections

Germany
University of Iowa
Holden Comprehensive Cancer Center

Completed

Nelfinavir in Recurrent Adenoid Cystic Cancer of the Head and Neck

Head and Neck Neoplasms | Carcinoma, Adenoid Cystic

United States
University of Wisconsin, Madison
Agouron Pharmaceuticals

Completed

Nelfinavir and M8 Drug-level Monitoring in HIV-1 Infection

HIV Infections

United States
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-TiDP29-C169: Bioavailability and Pharmacokinetics Trial Comparing Darunavir Pediatric Suspension Formulation to Current Darunavir Tablet

Pharmacokinetics
Mayo Clinic

Completed

Determining the Amount of Time Needed for Nelfinavir to Boost the Immune System in Adults

Immune Response

United States
French National Agency for Research on AIDS and...

Terminated

Evaluation of the Occurrence of Lipoatrophy in HIV-1 Infected Naive Patients

HIV Infections | HIV-Associated Lipodystrophy Syndrome

France
University of Colorado, Denver

Completed

Effects of Ledipasvir/Sofosbuvir on the Pharmacokinetics and Renal Safety of Tenofovir Alafenamide (TAF)

Hepatitis C | HIV Coinfection

United States
Mayo Clinic

Completed

The Effects of HIV Protease Inhibitors in Severe Sepsis

Sepsis

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Fosamprenavir Versus Other Protease Inhibitors

Infection, Human Immunodeficiency Virus I

United States, Puerto Rico
Northwell Health
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Terminated

Nelfinavir in Systemic Lupus Erythematosus (NISLE)

Systemic Lupus Erythematosus

United States
ViiV Healthcare
GlaxoSmithKline

Completed

A Phase 1 Antiretroviral Drug-Drug Interaction Study in Healthy Volunteers (DDI)

Infection, Human Immunodeficiency Virus

United States
ViiV Healthcare

Completed

Drug-drug Interaction (DDI) Study of GSK3640254 With Darunavir/Ritonavir (DRV/RTV) and Etravirine (ETR)

HIV Infections

United States
The University of Texas Health Science Center,...

Withdrawn

A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia

Cervical Dysplasia

United States
University of Iowa

Terminated

Study to Evaluate Using Nelfinavir With Chemoradiation for Non-small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
Pfizer

Completed

Thorough QT Study of Nelfinavir

Healthy Volunteers

Singapore, Belgium, United States
ANRS, Emerging Infectious Diseases
Janssen-Cilag Ltd.

Terminated

Management of Participants With Low-level Persistent Viremia (ANRS 161 L-VIR)

Viremia | HIV-1 Infection | Treatment Resistant Disorders

France
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C209: A Study of Safety of TMC114 With Low Dose Ritonavir (RTV) and Other Antiretrovirals in Experienced HIV-1 Infected Patients With Limited or no Treatment Options

HIV Infections
Medical College of Wisconsin

Not yet recruiting

Lexiva for the Treatment of LPR

Laryngopharyngeal Reflux

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma

Glioma

United States
ViiV Healthcare
Pfizer

Completed

Pharmacokinetics, Safety And Toleration Of Maraviroc Administered To Subjects With Various Degrees Of Renal Impaired And Normal Renal Function

Human Immunodeficiency Virus (HIV) Infection

Germany
Bristol-Myers Squibb

Terminated

A Phase IV Study of BMS-232632 in HIV+ Patients With Metabolic Syndrome

HIV Infections

France
Istituto Superiore di Sanità

Completed

Treatment of Classical Non-HIV-Related Kaposi's Sarcoma With the Antiviral Drug Indinavir

Classical Kaposi's Sarcoma

Italy
Merck Sharp & Dohme LLC

Completed

A Comparison of Two Dose Levels of Indinavir Combined With Two Nucleoside Analogue Reverse Transcriptase Inhibitors (NRTIs) in HIV-Infected Patients

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis

HIV Infections | Cytomegalovirus Retinitis

United States
ViiV Healthcare

Terminated

GW873140 In Combination With Kaletra In HIV Infected Subjects

HIV Infection | Infection, Human Immunodeficiency Virus I

United States, Germany, France, Canada, Spain, Italy, Portugal, United Kingdom, Denmark, Netherlands
Catholic University of the Sacred Heart

Terminated

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA) (GUSTA)

HIV Infection

Italy
Abramson Cancer Center of the University of Pennsylvania

Terminated

Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer

United States
Université Catholique de Louvain
Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Completed

Optimization of Darunavir Therapy and Dosage Recommendations

Human Immunodeficiency Virus I Infection

Belgium
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C202: A Study of Safety, Efficacy, and Tolerability of TMC114 and Low Dose Ritonavir in HIV-1 Infected Patients

HIV Infections

United States, Argentina
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors

Nasopharyngeal Cancer | Gastric Cancer | Hodgkin Lymphoma | Castleman Disease | Non-Hodgkin Lymphoma | Kaposi Sarcoma | EBV

United States
Brigham and Women's Hospital
National Institutes of Health (NIH)

Completed

A Pilot Study of Moderate Hyperbilirubinemia in Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

United States
Tibotec Pharmaceuticals, Ireland

Completed

An Open Label Trial of TMC114/RTV in HIV-1 Infected, Treatment-experienced Subjects.

HIV Infection

United States, Australia, France, United Kingdom, Germany, Spain, Belgium, Portugal, Canada, Argentina, Brazil, Austria, Hungary
Fundacion SEIMC-GESIDA
ViiV Healthcare

Completed

HCV Evolution in HIV/HCV (Genotype 1) Coinfected Patients Treated With Fosamprenavir (FOSTER-C)

HCV Coinfection | Chronic HIV Infection

Spain
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.

HIV | AIDS
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C201: A Study to Determine the Antiviral Activity of TMC114 in Patients With Multiple Protease Inhibitor (PI) Resistant Human Immunodeficiency Virus (HIV) Strains

HIV Infections
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in HIV-Positive Women

HIV Infections

United States
Agouron Pharmaceuticals

Completed

A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3

HIV Infections | Sarcoma, Kaposi

United States
Agouron Pharmaceuticals

Completed

Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants

HIV Infections

United States
Agouron Pharmaceuticals

Completed

Viracept Expanded Access Program

HIV Infections

United States

Search clinical trials for: Viral Protease Inhibitors

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