Search clinical trials for: Xanomeline and Trospium Chloride Capsules

Total 5556 results

Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-3)

Schizophrenia | Schizophrenia; Psychosis

United States, Ukraine
Karuna Therapeutics

Enrolling by invitation

An Extension Study to Assess Long-Term Safety and Tolerability of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia

Schizophrenia

United States, Bulgaria, Serbia, India, Poland, Romania, United Kingdom
Karuna Therapeutics

Active, not recruiting

An Open-label Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-5)

Schizophrenia

United States, Puerto Rico
Karuna Therapeutics

Completed

A Study to Assess Safety and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-1)

Schizophrenia

United States
Karuna Therapeutics

Completed

An Extension Study to Assess Long-term Safety, Tolerability, and Efficacy of KarXT in Adult Patients With Schizophrenia (EMERGENT-4)

Schizophrenia

United States, Ukraine
Karuna Therapeutics
Zai Lab (Shanghai) Co., Ltd.

Recruiting

A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia (UNITE-001)

Schizophrenia

China
Karuna Therapeutics

Recruiting

A Study to Assess Efficacy and Safety of Adjunctive KarXT in Subjects With Inadequately Controlled Symptoms of Schizophrenia (ARISE)

Schizophrenia

United States, Serbia, Bulgaria, India, Poland, Romania, United Kingdom
Karuna Therapeutics

Completed

A Study to Assess Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Adult Patients With Schizophrenia (EMERGENT-2)

Schizophrenia | Schizophrenia; Psychosis

United States
Karuna Therapeutics

Terminated

An Open-label Study to Assess the Long-term Safety, Tolerability, Effectiveness, and Durability of Effect of KarXT in Patients With DSM-5 Diagnosis of Schizophrenia (PENNANT)

Schizophrenia

United States
Karuna Therapeutics

Completed

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Schizophrenia

United States
University of North Carolina, Chapel Hill
American Urogynecologic Society

Completed

The Effect of Anticholinergics on Cognitive Function in the Elderly (ACE)

Urinary Bladder, Overactive | Cognitive Function | Mental Competency

United States
University of Calgary

Recruiting

CAlgary SAlt for POTS (CASA-POTS)

Postural Orthostatic Tachycardia Syndrome

Canada
Endo Pharmaceuticals
Alkermes, Inc.

Completed

Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Allergan

Completed

Efficacy of Sanctura XR (Trospium Chloride) for Reducing Overactive Bladder Symptoms in Female Subjects Refractory to Detrol LA (Tolterodine Tartrate Extended Release) Daily

Overactive Bladder

United States
Allergan

Completed

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial

Overactive Bladder | Pharmacokinetics | Elderly

United States
Allergan

Completed

Trospium Chloride XR in Obese Female Patients With Overactive Bladder

Obesity | Overactive Bladder | Incontinence

United States
Reata, a wholly owned subsidiary of Biogen

Completed

RTA 408 Capsules in Patients With Melanoma - REVEAL

Melanoma | Unresectable (Stage III) Melanoma | Metastatic (Stage IV) Melanoma

United States
Ain Shams University

Recruiting

Gabapentin Versus Trospium Chloride for Prevention of a Catheter-related Bladder Discomfort Inside the ICU

Catheter-related Bladder Discomfort (CRBD)

Egypt
The University of Texas Medical Branch, Galveston
National Institute on Aging (NIA)

Recruiting

Comparative Effectiveness of Initial OAB Treatment Options Among Older Women at High Risk of Falls

Urinary Bladder, Overactive | Urinary Incontinence | Accidental Falls

United States
Mansoura University
Amiri Hospital

Suspended

Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:

Quality of Life | Ureter Obstruction | Ureter Stone

Egypt
Allergan

Completed

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial

Overactive Bladder

United States
Becky Clarkson
National Institute on Aging (NIA)

Recruiting

Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence

Urgency Urinary Incontinence

United States
Hongsheng Tan
Shanghai Shen Kang Hospital Development Center; Longhua Hospital; Hongqiao International...

Completed

Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution (DL-MAFLD-TCM)

Fatty Liver

China
Allergan

Completed

Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

Healthy

United States
Taris Biomedical LLC

Completed

Safety and Tolerability of TAR-302-5018 in Subjects With Idiopathic Overactive Bladder

Idiopathic Overactive Bladder With Urinary Incontinence

United States
Taris Biomedical LLC

Completed

Safety and Tolerability of TAR-302-5018 in Subjects With Neurogenic Detrusor Overactivity Resulting From Spinal Cord Injury

Neurogenic Detrusor Overactivity

United States
Medical University of South Carolina

Withdrawn

Clinical Evaluation of the Use of Sealed Capsule Irrigation With Sodium Chloride During Pediatric Cataract Surgery and IOL Implantation

Cataract Extraction

United States
OPKO Health, Inc.

Completed

Safety/Efficacy Study of CTAP101 in Chronic Kidney Disease Subjects With Secondary Hyperparathyroidism (SHPT)

Chronic Kidney Disease | Secondary Hyperparathyroidism | Vitamin D Insufficiency

United States
Swansea University

Unknown

Does Salt Intake Improve Mood

Mood | Salt Intake

United Kingdom
Medtronic - MITG

Terminated

Feasibility Study to Evaluate the Performance of Flocculation-Adsorption System for Colon Cleansing Enhancement (RD-400)

Healthy

Israel
Dr. R. Pfleger Chemische Fabrik GmbH

Completed

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Pharmacokinetics | Drug Interaction Potentiation | Inhibition Enzyme
Psychiatric Hospital of the University of Basel

Terminated

Fecal Microbiota Transplantation in Depression

Major Depressive Disorder

Switzerland
POM Wonderful LLC

Completed

Safety and Efficacy of POMx Capsules in Men With Recurrent Prostate Cancer: An 18-Month Study

Recurrent Prostate Cancer

United States
Beijing Tiantan Hospital
NeuroDawn Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Minocycline in Patients With Moderate to Severe Acute Ischemic Stroke (EMPHASIS)

Ischemic Stroke, Acute

China
Jinling Hospital, China

Recruiting

Omega-3 PUFA for Treatment of Patients With Idiopathic Oligoasthenoteratospermia

Male Infertility Due to Hypospermatogenesis

China
Massachusetts General Hospital
Center for Microbiome Informatics and Therapeutics

Active, not recruiting

Fecal Microbiota Transplant as Treatment of Hepatic Encephalopathy

Hepatic Encephalopathy

United States
Han Yaling

Completed

Tongxinluo Improve High on Clopidogrel Platelet Reactivity Patients With Coronary Heart Disease (Talent)

Coronary Artery Disease

China
Natrogen Therapeutics International, Inc

Unknown

Efficacy and Tolerability Study of Natura-Alpha in the Treatment of Patients With Active Ulcerative Colitis

Ulcerative Colitis

United States
Al-Kindy College of Medicine

Completed

The Effect of Cinnamon on Patients With Chronic Prostatitis/Chronic Pelvic Pain Syndrome; a Pilot Study

Chronic Prostatitis | Chronic Pelvic Pain Syndrome

Iraq
Yale University

Completed

Cranberry for UTI Prevention in Residents of Long Term Care Facilities (PACS)

Urinary Tract Infection

United States
Medibiofarma S.L.

Completed

Study to Assess the Safety and Tolerability of MBF-118 in Healthy Volunteers

Cancer

Spain
POM Wonderful LLC
Target Health Inc.

Completed

POMx In the Treatment of Erectile Dysfunction

Erectile Dysfunction

United States
Pusan National University Hospital

Completed

Efficacy of Fenugreek Seed and Lespedeza Cuneata in TDS

Hypogonadism

Korea, Republic of
NanoSHIFT LLC

Terminated

Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars

Dental Pain

United States
Takeda

Completed

Evaluation of the Safety and Efficacy of Long-term Use of Omega-3 Fatty Acid Ethyl Esters

Hyperlipidemia

Japan
Garvan Institute of Medical Research

Completed

Alkaline Diet for Insulin Sensitivity (ADIS)

Type 2 Diabetes Mellitus | Dysglycemia

Australia
Palobiofarma SL
Clínica Universidad de Navarra

Completed

Study to Assess the Safety and Tolerability of PBF-1650 in Healthy Volunteers. (ADENOIMMUNE)

Psoriasis

Spain
Biota Pharma Europe Limited

Completed

Safety, Efficacy and Pharmacokinetics of BTA-C585 in a RSV Viral Challenge Study

Respiratory Syncytial Virus (RSV) Infection

United Kingdom
BioCryst Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan (APeX-J)

Hereditary Angioedema, HAE

Japan
M.D. Anderson Cancer Center
Bayer; Prostate Cancer Foundation

Completed

Radium 223 in Castrate Resistant Prostate Cancer Bone Metastases

Prostate Cancer

United States

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