Search clinical trials for: Z-521

Total 1953 results

United Biomedical

Completed

Study to Evaluate Safety and Pharmacokinetics of UB-421 Antibody in HIV-1 Infected Adults

HIV-1 Infection in Adults (Asymptomatic)

Taiwan
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)

Healthy Volunteer Study

Canada
Vicore Pharma AB

Completed

A Trial to Evaluate the Effect of C21 on Endothelial Dysfunction in Subjects With Type 2 Diabetes

Endothelial Dysfunction | Type2diabetes

Sweden
Canopy Growth Corporation
Centre hospitalier de l'Université de Montréal (CHUM); McGill University Health... and other collaborators

Terminated

Investigation of the Efficacy and Safety of CHI-921 in Insomnia.

Insomnia

Canada
Rutgers, The State University of New Jersey

Terminated

Randomized Comparison of Combination Azithromycin and Hydroxychloroquine vs. Hydroxychloroquine Alone for the Treatment of Confirmed COVID-19

COVID-19 | SARS-CoV-2

United States
Texas A&M University
Nutrabolt

Completed

Effects of a Pre-Workout Dietary Supplement on Training Adaptations (NB2)

Dietary Modification
Alanya Alaaddin Keykubat University

Completed

Effectiveness of Telerehabilitation Exercise for Bening Paroxysmal Positional Vertigo

Benign Paroxysmal Vertigo

Turkey
Allergan

Completed

Ocular Surface Tolerability Study of Prostaglandin Analogues in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

Canada, United States
Aptarion Biotech AG

Recruiting

Safety and Efficacy of AON-D21 in Severe Community-Acquired Pneumonia.

Community-acquired Pneumonia

Belgium, United Kingdom, Germany, France, Spain
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19 (MORNINGSKY)

COVID-19

Switzerland, Turkey, Denmark, Belgium, Japan, Mexico, Argentina, Brazil, Germany, Portugal, Romania, Ukraine
Chong Kun Dang Pharmaceutical

Completed

Evaluate the Drug-drugs Interaction Between Lobeglitazone 0.5mg and Empagliflozin 25mg

Type 2 Diabetes Mellitus

Korea, Republic of
David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Icosavax, Inc.

Completed

Safety and Immunogenicity of IVX-A12 in Healthy Older Adults

Healthy

United States
Hutchison Medipharma Limited

Completed

A Clinical Study to Evaluate the Pharmacokinetics and Bioequivalence of HMPL-523 Tablets Produced by Two Different Manufacturers

Healthy Subject

China
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19

COVID-19

Spain, Canada, United Kingdom, Greece, Ireland, Latvia
University of California, Los Angeles

Completed

Safety of Body Composition Analysis in Heart Failure Patients With Implantable Cardioverter Defibrillators (ICDs)

Heart Failure | Obesity

United States
Chong Kun Dang Pharmaceutical

Completed

An Evaluation of Glycemic Control Effects of Mono Therapy CKD-501 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Korea, Republic of
University of Pavia

Enrolling by invitation

Influence of Different Nanohybrid Flowable Composite Resin on Shear Bond Strength and Dimensional Changes of Invisalign Attachments After 6 Months of Brushing

Malocclusion

Italy
Hutchison Medipharma Limited

Active, not recruiting

HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (wAIHA)

Warm Antibody Autoimmune Hemolytic Anemia

China
Nutrasource Pharmaceutical and Nutraceutical Services...
Pharmalink International Ltd.

Completed

Assessment of PCSO-524 Relative to a Comparator Product

Healthy

Canada
B. Braun Melsungen AG
B.Braun Taiwan Co., Ltd.

Completed

Efficacy and Safety of a PN Regimen Containing n-3 Fatty Acid in Patients Considered After GI Surgery

GI Cancer

Taiwan
Pfizer

Terminated

Trial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis Fungoides

Melanoma | Soft Tissue Sarcoma | Mycosis Fungoides | Breast Carcinoma | Solid Tumors | Squamous Cell Carcinoma | Human Papillomavirus-Related Malignant Neoplasm | Merkel-cell Carcinoma

United States
Apollomics (Australia) Pty. Ltd.
Novotech (Australia) Pty Limited; Apollomics Inc. (formerly CBT Pharmaceuticals...

Terminated

APL-501 or Nivolumab in Combination With APL-101 in Locally Advanced or Metastatic HCC and RCC

Renal Cell Carcinoma | Hepatocellular Carcinoma

Australia, New Zealand
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant

Lymphoma, Non-Hodgkin | Acute Lymphoblastic Leukemia | Primary Immunodeficiency | Anemia, Sickle Cell | Hemoglobinopathies | Fanconi Anemia | Anemia, Aplastic | Myelodysplastic Syndrome | Thalassemia | Cytopenia | Diamond Blackfan Anemia | Osteopetrosis | Leukemia, Acute Myeloid (AML), Child

United Kingdom, Italy
Bial - Portela C S.A.

Completed

Effect of Food on BIA 6-512 (Trans-resveratrol)

Parkinson Disease

Portugal
Kala Pharmaceuticals, Inc.

Completed

Safety and Efficacy of KPI-121 in Subjects With Postsurgical Inflammation and Pain

Post Surgical Ocular Inflammation and Pain

United States
Rio de Janeiro State University
Universidade Federal Fluminense; Rio de Janeiro State Research Supporting Foundation...

Recruiting

Obesity and Bariatric Surgery According to a Biopsychosocial Perspective.

Depression | Quality of Life | Obesity | Anxiety Disorders | Heart Rate Variability

Brazil
University of Oxford
European and Developing Countries Clinical Trials Partnership (EDCTP); Medical...

Recruiting

A Study to Assess the Experimental Malaria Vaccines RH5.2-VLP and R21

Malaria, Plasmodium Falciparum

Gambia
Kowa Research Institute, Inc.

Completed

Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following Descemetorhexis

Fuchs' Endothelial Corneal Dystrophy

United States, Australia, Germany, Spain, Denmark
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy Followed by Radiation Therapy in Treating Younger Patients With Newly Diagnosed Localized Central Nervous System Germ Cell Tumors

Childhood Central Nervous System Germinoma | Central Nervous System Nongerminomatous Germ Cell Tumor

United States, Canada, Puerto Rico, Australia, New Zealand
Asahi Kasei Medical Co., Ltd.

Completed

Clinical Study of Asahi ViE Dialyzer in Canada (AVID)

Kidney Failure, Chronic
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
Ain Shams University

Not yet recruiting

Circulating microRNA 21 Expression Level Before and After Neoadjuvant Systemic Therapy in Breast Carcinoma

Breast Carcinoma

Egypt
Global Alliance for TB Drug Development

Completed

Evaluation of 8 Weeks of Treatment With the Combination of Moxifloxacin, PA-824 and Pyrazinamide in Patients With Drug Sensitive and Multi Drug-Resistant Pulmonary Tuberculosis (TB) (NC-002)

Pulmonary Tuberculosis

Tanzania, South Africa
Melaka Manipal Medical College

Unknown

Clinical Evaluation of Bulk-fill vs Layered Composite Resin in Class I and II Posterior Restorations

Dental Caries Class II | Dental Caries Class I (Disorder)

Malaysia
Cairo University

Unknown

One-year Clinical Evaluation of Bulk-fill Versus Conventional Incremental Posterior Restoration by FDI Criteria

Post Dental Restoration
Roswell Park Cancer Institute
Celgene

Active, not recruiting

SVN53-67/M57-KLH Peptide Vaccine in Treating Patients With Newly Diagnosed Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Plasma Cell Myeloma | Partial Response of Multiple Myeloma or Plasma Cell Leukemia

United States
Bellicum Pharmaceuticals

No longer available

BPX-501 T Cells Infused Post Stem Cell Transplant in Pediatrics With Non-Malignant Disorders Ineligible for BPU004 Study

Hurler Syndrome | Inborn Errors of Metabolism | Metachromatic Leukodystrophy | Inherited Metabolic Disorder | Lysosomal Storage Disorder

United States
Eisai Inc.

Completed

Phase 2, Parallel Group, Rollover Study of AKR-501 in Patients With ChronicITP Who Completed 28 Days of Study Treatment in Protocol 501-CL-003

Idiopathic Thrombocytopenic Purpura

United States
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder (MDD)

Depression | Major Depressive Disorder

United States, India
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating The Potential Interaction Between Verapamil Immediate Release And SAM-531 When Co-Administered

Alzheimer Disease

France
Othera Pharmaceuticals

Terminated

Study of OT-551 Eye Drops to Prevent or Delay Progression of Nuclear Cataracts Following Vitreous Removal

Epiretinal Membrane | Macular Hole

United States
MedImmune LLC

Completed

Safety/Efficacy of MEDI-551 in Combination With Immunomodulating Therapies in Subjects With Aggressive B-cell Lymphomas

Relapsed/Refractory Aggressive B-cell Lymphomas

United States
La Jolla Pharmaceutical Company

Approved for marketing

Expanded Access for LJPC-501

Sepsis | Vasodilatory Shock | Distributive Shock | High Output Shock | Catecholamine Resistant Hypotension (CRH)
Uzi Milman

Terminated

Magnesium Oxide Monohydrate for Nocturnal Leg Cramps (MgNLC)

Quality of Life | Nocturnal Leg Cramps

Israel
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Depression | Major Depressive Disorder | MDD

United States, Puerto Rico
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Efficacy and Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder.

Major Depressive Disorder

Croatia, Brazil, Bulgaria, France, Poland, Russian Federation, South Africa, Hungary, Romania, Ukraine, Argentina, Chile, Slovakia, Colombia, Germany, Serbia, Spain
Regeneron Pharmaceuticals
Bayer

Completed

Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)

Macular Degeneration

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Radiation Therapy Oncology Group; American...

Completed

Neoadjuvant and Adjuvant Imatinib Mesylate in Treating Patients With Primary or Recurrent Malignant Gastrointestinal Stromal Tumor

Gastrointestinal Stromal Tumor

United States
La Jolla Pharmaceutical Company

Terminated

A Phase 1 Study of LJPC-501 in Patients With Hepatorenal Syndrome

Hepatorenal Syndrome Type I and Type II

United States

Search clinical trials for: Z-521

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