Search clinical trials for: antiviral prophylaxis with Tenofovir Alafenamide Fumarate

Total 589 results

Nanfang Hospital of Southern Medical University
Gilead Sciences; Tigermed Consulting Co., Ltd

Recruiting

Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF)

Hepatitis B, Chronic | Mother to Child Transmission

China
Mahidol University

Recruiting

TDF Dose Adjustment VS. Switching to TAF in TDF-experienced CHB Patients With Renal Impairment

Renal Insufficiency | Tenofovir

Thailand
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Doravirine for Persons With Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide

HIV Infections

United States
Xi'an Xintong Pharmaceutical Research Co.,Ltd.
The First Hospital of Jilin University

Recruiting

A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB (HTS)

Pharmacokinetics | Efficacy | Safety

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis B

Chronic Hepatitis b

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Efficacy and Safety of TAF vs Other NAs in Patients With LVL

Chronic Hepatitis b | Cirrhosis Due to Hepatitis B

China
Janssen Sciences Ireland UC

Completed

Relative Bioavailability and Food Effect for Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Fixed Dose Combination

Healthy

Belgium
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Jiangsu Aidea Pharmaceutical Co., Ltd
Chengdu Aidea Pharmaceutical Technology Co., Ltd

Recruiting

Single Ascending Dose, Food Effects and Drug-Drug Interactions of ACC017 Tablets in Healthy Adult Participants

Healthy Adult Participants

China
University of California, San Diego
Gilead Sciences; University at Buffalo

Completed

Elvitegravir (EVG) Cerebrospinal Fluid (CSF) Pharmacokinetics in HIV-Infected Individuals

HIV

United States
Young-Suk Lim
Samsung Medical Center; Seoul National University Hospital; Korea University... and other collaborators

Completed

Switching From TDF to TAF vs. Maintaining TDF in Chronic Hepatitis B With Resistance to Adefovir or Entecavir.

Chronic Hepatitis b

Korea, Republic of
East Carolina University
Janssen Scientific Affairs, LLC

Recruiting

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

HIV Infections | Obesity

United States
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

The Efficacy and Safety of Nucleos(t)Ide Analogues in the Treatment of HBV-related Acute-on-chronic Liver Failure

Liver Failure | Virus Diseases | Hepatitis B

China
Merck Sharp & Dohme LLC

Completed

Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024) (Impower-024)

HIV Preexposure Prophylaxis

United States, Brazil, France, Japan, South Africa, Thailand, Peru
Janssen Research & Development, LLC

Completed

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat as Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared With Co-administration of the Separate Agents

Healthy

Netherlands
Janssen Pharmaceutica N.V., Belgium

Terminated

A Study in Healthy Participants to Assess the Effect of Darunavir, Emtricitabine, and Tenofovir Alafenamide in the Presence of Cobicistat When Administered as a Fixed Dose Combination (Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide) Compared to the Co-administration of the Separate Agents

Healthy

Netherlands
Humanity and Health Research Centre

Recruiting

Change of Renal Function and Bone Mineral Density in CHB Patients Switch From TDF to TAF vs. Maintaining TDF (SWITAF)

Chronic Hepatitis B

Hong Kong
University of California, Los Angeles
Gilead Sciences; University of Cape Town; Desmond Tutu HIV Foundation

Completed

PK of TAF and TDF for PrEP in Pregnant and Postpartum Women (PrEP-PP PK)

Hiv

South Africa
Yonsei University

Unknown

Switching From Tenofovir Disoproxi Fumarate to Tenofovir Alafenamide in Chronic Hepatitis B Patients With Antiviral Resistance

Hepatitis B | Antiviral Drug Adverse Reaction
Institute of Liver and Biliary Sciences, India

Recruiting

TAF (Tenofovir Alafenamide) for Preventing Progression of Liver Disease in Non-cirrhotic Chronic HBV Infection With Normal ALT and Low Viral Load.

Non-cirrhotic, Chronic Hepatitis B

India
Southeast University, China

Unknown

Study of Tenofovir Alafenamide Fumarate Tablets (TAF) in Blocking Mother-to-child Transmission of Hepatitis B Virus

Hepatitis B Virus | Mother to Child Transmission

China
Institut de Recherche pour le Developpement
Chiang Mai University; Ministry of Health, Thailand; Ministry of Health, Lao PDR

Active, not recruiting

Antiviral Prophylaxis and Infant Vaccination to Prevent Perinatal Hepatitis B Infection

Hepatitis B | Pregnancy

Thailand, Lao People's Democratic Republic
Janssen Sciences Ireland UC

Completed

A Bioequivalence Study of Darunavir, Emtricitabine, and Tenofovir Alafenamide, in the Presence of Cobicistat in Healthy Participants

Healthy

Netherlands
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b

Chronic Hepatitis b

China
Asian Pacific Liver Center at Coalition of Inclusive...

Unknown

TAF Switch Study in Hepatitis B Monoinfection

Hepatitis B
The First Affiliated Hospital of Zhengzhou University
National Natural Science Foundation of China; The Affiliated Nanjing Drum Tower... and other collaborators

Not yet recruiting

Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis B (TAF-PPT)

Chronic Hepatitis B | Efficacy | Safety | Hepatitis B Virus | Mother-to-Child Transmission | Tenofovir Alafenamide Fumarate
Janssen Pharmaceutica N.V., Belgium

Withdrawn

A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment (SALMONS)

Hepatitis B, Chronic

Germany, France, Italy, Spain, Denmark, Portugal, Greece
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA. (ALTHBV)

Hepatitis B Virus

China
Technical University of Munich

Completed

Dual Therapy With Boosted Darunavir + Dolutegravir (Dualis)

HIV-Infection

Germany
Janssen Research & Development, LLC

Terminated

A Single and Multiple Ascending Dose Study of JNJ-64457744

Healthy | Hepatitis B, Chronic

New Zealand
Nucorion Pharmaceuticals, Inc.
Ligand Pharmaceuticals

Completed

Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B

Chronic Hepatitis B

United States
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus

Hepatitis B | Hepatitis B, Chronic | HBV

Hong Kong
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Efficacy and Safety of Dolutegravir-Containing Versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and Their Infants (VESTED)

HIV Infections

United States, South Africa, Thailand, Botswana, Brazil, Tanzania, Zimbabwe, India, Uganda
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis

Hepatitis B | Compensated Cirrhosis

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF (HBV)

Acute-On-Chronic Liver Failure | Hepatitis B

China
Valley AIDS Council
Gilead Sciences

Not yet recruiting

Advanced HIV: Outcomes for Rapid ART (AHORA)

HIV-1-infection
University of Nebraska
Gilead Sciences

Completed

Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Patients With Active Illicit Substance usE (BASE)

HIV-1-infection

United States
Fenway Community Health

Completed

Biktarvy for Non-Occupational Post-Exposure Prophylaxis (nPEP)

HIV Prevention

United States
Zhongshan Hospital (Xiamen), Fudan University

Recruiting

Study on Screening, Verification and Intervention of High-risk Patients With Liver Cancer

Hepatocellular Carcinoma | Chronic Hepatitis B

China
SWOG Cancer Research Network
National Cancer Institute (NCI)

Terminated

Prophylactic Antiviral Therapy in Patients With Current or Past Hepatitis B Virus Infection Receiving Anti-Cancer Therapy for Solid Tumors

Malignant Solid Neoplasm | Hepatitis B Infection

United States, Guam
Johns Hopkins University
Gilead Sciences

Completed

Analysis of Crushed and Whole Tablet Genvoya

Healthy Volunteers

United States
New Discovery LLC

Unknown

Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical Transmission

Hepatitis B, Chronic | Pregnancy Related

China
National Taiwan University Hospital
Mackay Memorial Hospital; Kaohsiung Medical University Chung-Ho Memorial Hospital and other collaborators

Unknown

Same-day Antiretroviral Therapy With BIC/F/TAF

HIV Infections

Taiwan
National Institute of Allergy and Infectious Diseases...
Microbicide Trials Network

Completed

Bone Mineral Density Substudy - An Ancillary Study to MTN-003

HIV Infections

Zimbabwe, Uganda
Assembly Biosciences

Completed

A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection

Chronic Hepatitis B

New Zealand, United States, Canada
Emory University
Centers for Disease Control and Prevention

Completed

Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens

HIV/AIDS

United States
Thomas Jefferson University
University of Illinois at Chicago; University of California, San Francisco; Nova... and other collaborators

Completed

The Incidence and Severity of Drug Interactions Before and After Switching Antiretroviral Therapy to Bictegravir/Emtricitabine/Tenofovir Alafenamide in Treatment Experienced Patients

HIV/AIDS

United States
University of Maryland, Baltimore
Gilead Sciences

Completed

B/F/TAF Switch Study for HIV-HBV Coinfection (BEST-HBV)

Hepatitis B | HIV-1-infection

United States
HQ Toronto
Gilead Sciences

Active, not recruiting

Express Testing and Same-day Initiation of PrEP Study (Express-PrEP)

HIV Prevention

Canada

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