Search clinical trials for: Atezolizumab

Total 755 results

Hoffmann-La Roche

Terminated

A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC).

Castration-Resistant Prostatic Cancer

Spain, France, Switzerland, Italy
Weill Medical College of Cornell University

Terminated

A Phase II Randomized Trial of Immunotherapy Plus Radiotherapy in Metastatic Genitourinary Cancers

Metastatic Renal Cell Carcinoma | Metastatic Urothelial Carcinoma

United States
Bristol-Myers Squibb

Completed

Multiple Ascending Dose (MDX1105-01) (Anti-PDL1)

Cancer, Multiple Indications

United States
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab Plus Bevacizumab Versus Active Surveillance as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical Resection or Ablation (IMbrave050)

Carcinoma, Hepatocellular

United States, Korea, Republic of, Belgium, China, Japan, Brazil, Italy, Spain, Thailand, Australia, Costa Rica, Austria, France, Singapore, Taiwan, New Zealand, Canada, Germany, Hong Kong, Peru, Mexico, Netherlands, Czechia, Turkey, Po... and more
Columbia University
Genentech, Inc.

Active, not recruiting

Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies (MEKiAUTO)

Gastrointestinal Cancer

United States
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab (Tecentriq) in Combination With Bevacizumab to Investigate Safety and Efficacy in Patients With Unresectable Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy-Amethista (AMETHISTA)

Carcinoma, Hepatocellular

Italy
Howard S Hochster
Genentech, Inc.; Rutgers Cancer Institute of New Jersey

Active, not recruiting

A Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma (AB7)

Unresectable Hepatocellular Carcinoma

United States
Hoffmann-La Roche

Completed

Atezolizumab in Combination With Bevacizumab in Patients With Unresectable Locally Advanced or Metastatic Mucosal Melanoma

Melanoma

China
M.D. Anderson Cancer Center
Helsinn Healthcare SA

Withdrawn

Phase Ib Trial of Infigratinib In Combination With Atezolizumab And Bevacizumab for The Second-Line Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion/Amplification

Cholangiocarcinoma | Liver Cancer

United States
AI Therapeutics, Inc.

Completed

A Phase I Dose Escalation Study of the Safety and Pharmacokinetics of LAM-002A In Patients With Non-Hodgkin's Lymphoma (LAM-002A/NHL) (LAM-002A/NHL)

Lymphoma, Non-Hodgkin; Leukemia, Chronic Lymphocytic

United States
University Hospital, Grenoble
NETRIS Pharma

Recruiting

Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC (Liver-NET1)

Hepatocellular Carcinoma

France
Gustave Roussy, Cancer Campus, Grand Paris

Suspended

Efficacy and Safety of the Combination of Rucaparib (PARP Inhibitor) and Atezolizumab (Anti-PD-L1 Antibody) in Patients With DNA Repair-deficient or Platinum-sensitive Solid Tumors (ARIANES)

Solid Tumor

France
Tae Won Kim

Recruiting

DYNAmic Immune Microenvironment of HCC Treated With atezolIzumab Plus bevaCizumab (DYNAMIC)

Hepatocellular Carcinoma

Korea, Republic of
Federation Francophone de Cancerologie Digestive

Recruiting

Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox, Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer (SIRTCI)

Metastatic Colorectal Cancer | MSS | pMMR | Immune Checkpoint Inhibitor | Internal Radiotherapy

France
Dana-Farber Cancer Institute
Genentech, Inc.

Active, not recruiting

Study of Atezolizumab + Bevacizumab in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma

Advanced Non-Clear Cell Kidney Cancer

United States
M.D. Anderson Cancer Center

Withdrawn

A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular Carcinoma

Metastatic Hepatocellular Carcinoma

United States
Oncology Center of Biochemical Education And Research

Completed

Atezolizumab in Large Cell Neuroendocrine Carcinoma (LANCE)

Large Cell Neuroendocrine Carcinoma of the Lung

Greece
Chang Gung Memorial Hospital

Not yet recruiting

Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma (PhotonAB)

Hepatocellular Carcinoma

Taiwan
National Taiwan University Hospital

Recruiting

Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC Patients

Locally Advanced Esophageal Squamous Cell Carcinoma

Taiwan
Massachusetts General Hospital
Genentech, Inc.

Recruiting

SBRT + Atezolizumab + Bevacizumab in Resectable HCC

Hepatocellular Carcinoma | Resectable Hepatocellular Carcinoma

United States
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

Rectal Cancer | Rectal Neoplasms

China
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab in Combination With Bevacizumab in Spanish Patients With Unresectable or Unsuitable for Locoregional Treatments Hepatocellular Carcinoma Not Previously Treated With Systemic Therapy

Carcinoma, Hepatocellular

Spain
Hoffmann-La Roche

Terminated

A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread

Breast Cancer

Israel, Italy, Spain, United States, Belgium, Czechia, Australia, United Kingdom, Korea, Republic of, Romania, France, Taiwan, Latvia
Georgetown University
Genentech, Inc.; Natera, Inc.

Recruiting

Evaluating Novel Therapies in ctDNA Positive GI Cancers (MRD-GI)

Hepatocellular Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Rectal Adenocarcinoma | Colon Adenocarcinoma | Gallbladder Adenocarcinoma | Adenocarcinoma of Biliary Tract

United States
Duke University

Terminated

Atezolizumab and Bevacizumab in EGFR Mutant NSCLC in Patients With Progressive Disease After Receiving Osimertinib

Non Small Cell Lung Cancer

United States
University Health Network, Toronto

Withdrawn

Maintenance Treatment With Bevacizumab and Atezolizumab for Ovarian Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | Ovarian Endometrioid Tumor | TP53 Mutation

Canada
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Withdrawn

Investigating Atezolizumab in Newly Diagnosed ER Positive Breast Cancer Patients According to Their AdipOsity (AteBrO)

Breast Cancer
Ardigen
National Center for Research and Development, Poland

Unknown

BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics

Melanoma | Non Small Cell Lung Cancer | Metagenome | Immunotherapy | Microbiome

Poland
Memorial Sloan Kettering Cancer Center
University of Pennsylvania; Genentech, Inc.

Completed

Paclitaxel, Trastuzumab, and Pertuzumab in the Treatment of Metastatic HER2-Positive Breast Cancer

Breast Cancer

United States
Daiichi Sankyo
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Extensive Stage-small Cell Lung Cancer
Hoffmann-La Roche
Jazz Pharmaceuticals

Active, not recruiting

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer (IMforte)

Small-Cell Lung Cancer

United States, Belgium, Italy, Spain, Turkey, United Kingdom, Korea, Republic of, Germany, Mexico, Hungary, Taiwan, Greece, Poland
Chang Gung Memorial Hospital

Recruiting

Atezolizumab and Bevacizumab With Proton Radiotherapy for Unresectable Hepatocellular Carcinoma (ProtonAB)

Hepatocellular Carcinoma Non-resectable

Taiwan
Genentech, Inc.

Recruiting

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Patients With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis (Kirros)

Hepatocellular Carcinoma

United States, Puerto Rico
Massachusetts General Hospital
Genentech, Inc.

Not yet recruiting

Atezolizumab+Bevacizumab+SBRT in Unresectable HCC

Unresectable Hepatocellular Carcinoma

United States
Jeffrey Clarke
Genentech, Inc.; Duke University

Terminated

Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases

Small-cell Lung Cancer | Brain Metastases

United States
Hoffmann-La Roche

Completed

A Study to Assess the Pharmacokinetics, Efficacy, and Safety of Atezolizumab Administered Intravenously (IV) as a Single Agent or in Combination With Chemotherapy in Chinese Participants With Locally Advanced or Metastatic Solid Tumors (IMYO29233)

Neoplasms

China
Inimmune Corporation
Avance Clinical Pty Ltd.

Not yet recruiting

Trial of INI-4001 in Patients With Advanced Solid Tumours

Advanced Solid Tumor

Australia
Genentech, Inc.

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

Advanced Solid Tumors | Metastatic Solid Tumors

Canada, Korea, Republic of, United States, Brazil, Australia, Argentina, Spain, New Zealand, Poland
University Health Network, Toronto
Hoffmann-La Roche

Recruiting

An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)

Hepatocellular Carcinoma | Liver Metastases | Non-small Cell Lung Cancer Metastatic

Canada
Elizabeth Buchbinder, MD
Genentech, Inc.

Recruiting

A Phase II Trial of PD-L1 Therapy Combined With Anti-VEGF Therapy in Unresectable or Metastatic Melanoma

Stage IV Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Unresectable Stage III Cutaneous Melanoma | Unresectable Stage IV Cutaneous Melanoma

United States
Hoffmann-La Roche

Active, not recruiting

A Study in Participants Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study (IMbrella A)

Cancer

United States, Canada, France, Italy, Slovenia, Spain, Turkey, United Kingdom, Argentina, Brazil, Poland, Australia, Czechia, Thailand, Korea, Republic of, Russian Federation, Switzerland, Japan, Taiwan, Austria, Hungary, Belgium, P... and more
Centre Leon Berard

Active, not recruiting

Atezolizumab and Bevacizumab in Patients With Recurrent or Metastatic Squamous-cell Carcinoma of the Head and Neck (ATHENA)

Head and Neck Neoplasms

France
Alliance Foundation Trials, LLC.
Eli Lilly and Company; Pfizer; Genentech, Inc.; Foundation Medicine

Recruiting

A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer (EndoMAP)

Endometrial Cancer

United States
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma

Hepatocellular Carcinoma

Austria, Germany, Spain, Japan, Italy, France
Nabil Adra
Genentech, Inc.; Indiana University School of Medicine

Terminated

Trial of Atezolizumab Plus Chemotherapy After Progression on PD-1 or PD-L1 in Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma

Urothelial Carcinoma

United States
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer (SKYSCRAPER-02)

Small Cell Lung Cancer

Taiwan, United States, Hungary, Korea, Republic of, Belgium, United Kingdom, Spain, Brazil, Germany, Poland, Australia, Singapore, Italy, Switzerland, Turkey, Japan, Netherlands, Austria, Greece, Czechia, New Zealand, Russian Federation and more
M.D. Anderson Cancer Center

Active, not recruiting

Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma

Stage III Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIA Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IIIB Intrahepatic Cholangiocarcinoma AJCC v8 | Stage IV Intrahepatic Cholangiocarcinoma AJCC v8 | Metastatic Intrahepatic Cholangiocarcinoma | Locally Advanced Intrahepatic Cholangiocarcinoma

United States
Sun Yat-sen University

Recruiting

HAIC Plus A+T for Patients With High-risk HCC: a Single-arm Phase 2 Trial

Hepatocellular Carcinoma

China
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Atezolizumab in Treating Patients With Recurrent BCG-Unresponsive Non-muscle Invasive Bladder Cancer

Recurrent Bladder Urothelial Carcinoma | Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage I Bladder Urothelial Carcinoma AJCC v6 and v7

United States, Canada
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

BEACON - ABC in Recurrent Platinum Resistant HGSOC (BEACON)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

Australia

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