Search clinical trials for: beta-blocker (Metoprolol)

Total 16915 results

University Hospital Schleswig-Holstein

Completed

Intravenous Beta-blockade for Improvement of Autonomic Activity

Hypertension | Tachycardia | Heart Rate Variability

Germany
Hannover Medical School
Charite University, Berlin, Germany

Unknown

Cardiovascular Effects of Selective I(f)-Channel Blockade

Postural Orthostatic Tachycardia Syndrome

Germany
University of Vermont

Recruiting

Atrial Fibrillation: Chronic Beta-blocker Use Versus As-needed Rate Control Guided by Implantable Cardiac Monitor

Atrial Fibrillation | Diastolic Dysfunction | HFpEF - Heart Failure With Preserved Ejection Fraction

United States
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Completed

Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm

Mitral Stenosis

Bangladesh
Elpen Pharmaceutical Co. Inc.

Withdrawn

Comparison of Effectiveness of Ranolazine Plus Metoprolol Combination vs. FlecainidE pluS Metoprolol Combination in ATrial Fibrillation Recurrences FOllowing PhaRmacological or Electrical CardioverSion of AtRial Fibrillation (PRESERVE-SR)

Recurrence | Atrial Fibrillation
University of Chicago
Washington University School of Medicine; National Heart, Lung, and Blood Institute...

Completed

Metoprolol to Reduce Perioperative Myocardial Injury (ORION)

Heart Diseases

United States
Boston University

Withdrawn

Assessment of Intravenous Rate Control Response in Atrial Fibrillation Trial (AIRCRAFT) (AIRCRAFT)

Atrial Fibrillation

United States
Trinity Hypertension & Metabolic Research Institute

Completed

Efficacy and Safety of Nebivolol Versus Metoprolol in Hypertensive Subject Taking Amlodipine

JNC 7 Stage 1 or 2 Hypertension

United States
AstraZeneca
St. John's Research Institute

Completed

A Study to Compare the Efficacy, Safety and Tolerability of Selomax With Its Individual Components (MARS)

Primary Hypertension

India
Saniona

Completed

A Study to Examine the Effect of Tesofensine and Metoprolol on the 24-hour Mean Heart Rate

Phase 1

Germany
East Coast Institute for Research

Completed

Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function

Hypertension | Female Sexual Dysfunction

United States
Mylan Bertek Pharmaceuticals

Completed

Evaluation of the Long-term Safety and Tolerability of Metoprolol Versus Nebivolol in Patients With Hypertension

Hypertension

United States
Federico II University

Completed

Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome (PLATE-BLOCK)

Acute Coronary Syndrome

Italy
St. Luke's-Roosevelt Hospital Center
Medtronic

Terminated

BOAT: Beta Blocker Uptitration With OptiVol After Cardiac Resynchronization Therapy (CRT)

Congestive Heart Failure

United States
University of Cincinnati

Terminated

Sympathetic Nervous System Modulation in Hypertension

Hypertension
Forest Laboratories

Completed

Study of the Glycemic Effects of Nebivolol Compared With Metoprolol and HCTZ in Diabetic Hypertensive Patients

Hypertension | Type 2 Diabetes Mellitus

United States, Puerto Rico
First Affiliated Hospital of Harbin Medical University

Unknown

Effects of Metoprolol and Amlodipine on Cardiac Remodeling, Arrhythmias and Blood Pressure Variation in Hypertensive Patients With Sleep Apnea Syndrome

Hypertension | Sleep Apnea Syndrome

Hungary, China
AstraZeneca

Completed

Metoprolol in Acute Myocardial Infarction. A PK/PD Study

Acute Myocardial Infarction
Fundación Centro Nacional de Investigaciones Cardiovasculares...

Recruiting

TREatment With Beta-blockers After myOcardial Infarction withOut Reduced Ejection fracTion"

Myocardial Infarction

Spain, Italy
Weill Medical College of Cornell University
National Institute on Aging (NIA)

Completed

Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
University of Minnesota
University of Alabama at Birmingham; United States Department of Defense

Terminated

Beta-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United States
Bright Future Pharmaceuticals Factory O/B Bright...
Chinese University of Hong Kong

Unknown

Clinical Bioequivalence Study on Two Metoprolol Tablet 100mg Formulations

Healthy
Oslo University Hospital
University of Oslo; The Research Council of Norway

Recruiting

Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse (FLECAPRO)

Mitral Valve Prolapse | Ventricular Arrhythmias and Cardiac Arrest

Norway
University of Pennsylvania
Julio Chirinos, MD, PhD; Raymond Townsend, MD

Recruiting

BLOCKade of Calcium Channels and Beta Adrenergic Receptors for the Treatment of Hypertension in HFpEF (BLOCK HFpEF)

Hypertension | Heart Failure With Preserved Ejection Fraction

United States
RaeAnn Hirschy

Completed

Diltiazem vs. Metoprolol in the Acute Management of AF in Patients With HFrEF

Heart Failure | Atrial Fibrillation
AHEPA University Hospital
Skylitseio General Hospital

Completed

Beta Blockers Plus Intravenous Flecainide for Paroxysmal Atrial Fibrillation: a Real-world Chios Registry (BETAFLEC-CHIOS) (BETAFLEC-CHIOS)

Atrial Fibrillation | Arrhythmias, Cardiac

Greece
Weill Medical College of Cornell University
The New York Community Trust

Completed

Impact of Beta-blockers on Physical Function in HFpEF

Heart Failure | Heart Disease | Heart Failure, Diastolic | Heart Failure With Preserved Ejection Fraction | Cardiac Failure

United States
Janssen Research & Development, LLC

Withdrawn

A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants

Healthy

United States
Harbin Medical University
Beijing Chao Yang Hospital

Completed

Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients

Heart Failure | Anterior Myocardial Infarction

China
University of Florida
Food and Drug Administration (FDA)

Completed

Open-Labeled PK-PD Studies of Metoprolol ER

Blood Pressure

United States
Boehringer Ingelheim

Terminated

Telmisartan Effectiveness on Left Ventricular Mass Reduction (TELMAR) as Assessed by MRI, in Patients With Mild to Moderate Hypertension

Hypertension
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI); GlaxoSmithKline; AstraZeneca

Completed

Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart (BORG)

Idiopathic Dilated Cardiomyopathy

United States
University of Calgary
Vanderbilt University

Active, not recruiting

Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects

Vasovagal Syncope

Canada
Mahidol University

Recruiting

Heart Rate Controller in Computed Tomography Coronary Angiography

Heart Rate | Coronary Computed Tomography Angiography

Thailand
Wake Forest University Health Sciences

Terminated

Using Beta Blockers to Treat Mitral Regurgitation (REGURG)

Mitral Regurgitation | Mitral Valve Insufficiency | Heart Disease | Heart Valve Disease

United States
Xuanwu Hospital, Beijing
Tianjin Lerentang factory

Completed

Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.

Premature Ventricular Contraction
First Affiliated Hospital of Harbin Medical University

Unknown

The Effects of Nifedipine and Metoprolol on Blood Pressure Variability in Northern Chinese

Hypertension

Hungary
Forest Laboratories
Mylan Laboratories

Terminated

Study to Evaluate Symptoms in Patients Treated With Nebivolol or Metoprolol Extended-release (ER) for Hypertension

Hypertension

United States
Neutec Ar-Ge San ve Tic A.Ş

Not yet recruiting

S-Metoprolol XR 25-50 mg Tablets vs Metoprolol Zok 50-100 mg Tablets in Hypertension Patients.

Hypertension
University of Michigan

Completed

Evaluation of Metoprolol Pharmacokinetics in Patients Receiving Hi Flux Hemodialysis

Hemodialysis | Pharmacokinetics

United States
Washington University School of Medicine

Completed

Pilot - Peri-operative Beta Blockade

Adrenergic Beta-Receptor Blockader | Troponin Levels | Cardiomyopathy, Post-surgical

United States
AstraZeneca

Completed

307B - Safety, Tolerability and Pharmacokinetics Study of TOPROL-XL® in Hypertensive Pediatric Subjects

Hypertension

United States, Dominican Republic
Mayo Clinic
AstraZeneca

Completed

A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.

Heart Valve Diseases

United States
Astellas Pharma Inc

Completed

To Compare Blood and Urine Concentrations of Mirabegron (YM178) in Healthy Poor or Extensive Metabolizers for CYP2D6 and to Assess the Effect of Mirabegron on the Metabolism of Metoprolol

Healthy Subjects | Pharmacokinetics of Mirabegron

Netherlands
Bispebjerg Hospital
Odense University Hospital; Zealand University Hospital; Hvidovre University... and other collaborators

Recruiting

Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction (DANBLOCK)

ST Elevation Myocardial Infarction | Acute Myocardial Infarction | Non-ST Elevation Myocardial Infarction (nSTEMI)

Denmark
Shiraz University of Medical Sciences

Completed

Effect of Metoprolol on Thalassemia Cardiomyopathy

B Thalassemia

Iran, Islamic Republic of
AstraZeneca

Completed

Dose Ranging, Safety and Tolerability of TOPROL-XL® Extended-Release Tablets in Hypertensive Pediatric Subjects (307A)

Hypertension

United States, Dominican Republic
Saniona

Completed

48 Weeks, Study to Evaluate Overall Safety and Tolerability of Co-administration of Tesofensine and Metoprolol in Subjects With Hypothalamic Injury-induced Obesity (HIO)

Hypothalamic Injury-induced Obesity (HIO)

Denmark
Hackensack Meridian Health

Terminated

Post-Acute Sequelae of Coronavirus-19 (COVID-19) With Dyspnea on Exertion And Associated TaChycardia TrEatment Study (PEACE)

COVID-19 | Tachycardia | Dyspnea

United States
Vanderbilt University Medical Center

Completed

Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery (PREEMPTIVE)

Post-operative Atrial Fibrillation

United States

Search clinical trials for: beta-blocker (Metoprolol)

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