Search clinical trials for: biological agents

Total 188652 results

University Hospital, Lille

Completed

Biological Meshes in Infected Fields: a Randomized Controlled Trial (SIMBIOSE)

Ventral Hernia

France
Hoffmann-La Roche

Completed

Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs)

Juvenile Idiopathic Arthritis
Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Nanfang Hospital of Southern Medical University
Southern Medical University, China

Unknown

Long-term Prognosis and Quality of Life in Early Rheumatoid Arthritis Patients Treated by 2015 ACR Guideline (LELAND) (LELAND)

Rheumatoid Arthritis
University Hospital, Bordeaux

Recruiting

Mobile Technologies and Post-stroke Depression (MOTIV-POSDEP)

Depression | Stroke

France
Janssen Biotech, Inc.

Completed

Golimumab Safety and Surveillance Program Using the Ingenix NHI Database

Rheumatoid Arthritis | Arthritis, Psoriatic | Ankylosing Spondylitis
Hualan Biological Engineering, Inc.

Completed

Clinical Trial of the Inactivated Influenza Vaccine (0.25ml Formulation for Pediatric Use)

Influenza

China
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
University of Calgary
University of British Columbia; B. Braun Medical Inc.

Completed

Blood Pressure Guided Biofeedback on Hemodialysis and the Reduction of IntraDialytic Hypotension (BP-RIDH)

Hypotension

Canada
AstraZeneca

Completed

Study Will Assess the Safety, Neutralizing Activity and Efficacy of AZD3152 in Adults With Conditions Increasing Risk of Inadequate Protective Immune Response After Vaccination and Thus Are at High Risk of Developing Severe COVID-19 (NOVELLA)

COVID-19, SARS-CoV-2

Russian Federation
Sun Yat-sen University

Not yet recruiting

the SDMEAI Study: a Multi-center Epidemiological Study

Artificial Intelligence | Eye Involvement of Systemic Diseaes | Adverse Drug Effect on Eye
Burzynski Research Institute

Withdrawn

Antineoplaston Therapy in Treating Patients With Mantle Cell Lymphoma

Recurrent Mantle Cell Lymphoma | Stage III Mantle Cell Lymphoma | Stage IV Mantle Cell Lymphoma | Contiguous Stage II Mantle Cell Lymphoma | Noncontiguous Stage II Mantle Cell Lymphoma

United States
Burzynski Research Institute

Withdrawn

Antineoplaston Therapy in Treating Women With Advanced Breast Cancer

Stage IV Breast Cancer | Recurrent Breast Cancer

United States
Istituto Ortopedico Rizzoli

Completed

Observational Retrospective Study on the Clinical and Radiographic Outcomes of the Aseptic Pseudarthrosis Treatment of the Upper Limb

Pseudarthrosis

Italy
Burzynski Research Institute

Withdrawn

Antineoplaston Therapy in Treating Patients With Primary Central Nervous System Lymphoma

Primary Central Nervous System Lymphoma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Genetic and Molecular Characterization of Nervous System Lesions (ONCONEUROTEK 2)

Brain Tumor | Brain Lesion (General)

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Periodontitis and Inflammation: Study on Biological Samples (CB-PARO2)

Periodontitis

France
Centre Hospitalier Universitaire de Nīmes

Completed

Grinding Versus Standard Methods for the Treatment of Per-operative Bacteriological Samples Associated With Osteo-articular Sepsis (IOAP Turrax)

Bacterial Infection

France
University Hospital, Tours

Recruiting

Study of the Medullary Microenvironment in Acute Childhood Leukemia (MILA)

Acute Lymphoid Leukemia | Acute Myeloid Leukemia in Children

France
Imagine Institute
Reference center for rare diseases (Rare Gynecologic Diseases)

Recruiting

Molecular Genetic Study of Mayer-Rokitansky-Kuster-Hauser Syndrome (MRKH)

Mayer Rokitansky Kuster Hauser Syndrome

France
Centre Hospitalier Sud Francilien

Completed

Relationship Between Fungal Colonization and Severe Bronchopulmonary Dysplasia (FunDyP)

Fungal Infection | Bronchopulmonary Dysplasia | Extreme Prematurity

France
New York Stem Cell Foundation Research Institute
Silverstein Foundation

Recruiting

Drug Discovery for Parkinson's With Mutations in the GBA Gene

Healthy | Parkinson Disease | Gaucher Disease | GBA Gene Mutation

United States
University Hospital, Grenoble
University Hospital, Marseille

Completed

Anti-ficolin-2 Autoantibodies in Lupus Nephritis (Ficolupus2)

Lupus Erythematosus, Systemic
Aibin Liang，MD，Ph.D.
CARsgen Therapeutics Co., Ltd.

Recruiting

Assess the Safety and Efficacy of CT0594CP Cells in Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia

Relapsed and/or Refractory Multiple Myeloma | Plasma Cell Leukemia in Relapse

China
Kyushu University

Recruiting

Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors

Pediatric Solid Tumors | Refractory/Relapse Neuroblastoma

Japan
GAIA BioMedicine Inc.

Recruiting

Clinical Trial of GAIA-102 for Advanced and Relapse NSCLC

NSCLC | Cell Therapy

Japan
Centre Hospitalier Universitaire de Besancon

Not yet recruiting

Antitumor T Cell Responses in Patients With Bladder Cancer (immunoBLAD)

Bladder Cancer
University of Lorraine

Recruiting

Traumatic Events in Childhood, Attachment, Pain Perception, Epigenetic Marks, Quality of Life and Resilience.

Quality of Life | Chronic Pain | Resilience, Psychological | Adverse Childhood Experiences | Chronic Stress | Attachment Styles | Epigenesis, Genetic

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples (NT21)

Periodontitis | Trisomy 21

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Exploration of Allograft Humoral Rejection in Chronic Histiocytic Intervillositis (RH-PL)

Miscarriage | Intrauterine Growth Retardation | Chronic Histiocytic Intervillositis | Fetal Death in Utero

France
Centre Hospitalier Universitaire de Nice
French Society of Rheumatology

Recruiting

Thromboxane A2 and Osteoarthritis

Osteoarthritis

France
Central Hospital, Nancy, France

Not yet recruiting

SARS-CoV-2 in Stools Compared to Respiratory Viral Strains. (Spread-COVID)

SARS-CoV-2 Infection

France
Assiut University

Not yet recruiting

Hematological Indices and Fecal Calprotectin Predict Histological Remission in Ulcerative Colitis

Ulcerative Colitis
University Hospital, Brest

Not yet recruiting

Determinants of Repeated Spontaneous Miscarriages and Unexplained Fetal Deaths (DEFI-2)

Repeated Spontaneous Miscarriages | Fetal Deaths in Utero

France
Institut Paoli-Calmettes
AstraZeneca

Recruiting

Circulating Tumor DNA as an Early Marker of Recurrence and Treatment Efficacy in Ovarian Carcinoma (CIDOC)

Ovarian Carcinoma

France
RWTH Aachen University

Recruiting

Development of a Biological Database in the Field of Operative Intensive Care (Biobank OIM)

Intensive Care in General

Germany
Institut de cancérologie Strasbourg Europe

Completed

Effect of Irradiation Doses < 10 Gy and of Irradiated Bone Volume on the Variation of Blood Elements of the Complete Blood Count During and After Pelvic Irradiation (MIFADORESOL)

Vaginal Cancer | Prostate Carcinoma | Radiotherapy | Rectum Carcinoma | Cervix Carcinoma | Anal Canal Carcinoma | Endometrium Carcinoma

France
Achilles Therapeutics UK Limited

Terminated

Long-Term Follow-Up Study of Patients Receiving ATL001

Melanoma | Advanced Non Small Cell Lung Cancer

United Kingdom
Centre Hospitalier Universitaire de la Réunion

Completed

Clinical and Biological Strokes Collection in Reunion Island (CoBRA)

Stroke

Réunion
Centre Hospitalier Universitaire de Besancon

Completed

Study of Anti-telomerase T CD4 Immunity in Metastatic Lung Cancer (Telocap02)

Lung Cancer

France
Centre Hospitalier Universitaire de Besancon

Completed

Targeting Leukemic Stem Cell Expressing the IL-1RAP Protein in Chronic Myelogenous Leukemia (CML) (CAR-LMC)

Chronic Myeloid Leukemia

France
Centre Hospitalier Universitaire de Nice

Completed

Diagnosic and Pronostic Values of Kappa and Lambda Free Light Chains in Central Nervous System Inflammatory Diseases

Central Nervous System Diseases | Multiple Sclerosis

France
Nantes University Hospital

Completed

Anti-BK Virus Immune Response and Kidney Transplantation (BKv)

Kidney Transplantation

France
Assistance Publique - Hôpitaux de Paris

Completed

Perinatal Consequences of Endometriosis (ENDOBST)

Endometriosis

France
Institut du Cancer de Montpellier - Val d'Aurelle

Completed

Medical and Surgical Management of Patients With Brain Metastases (CEREMET-LR)

Central Nervous System Tumor

France
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France; ScreenCell; Celen... and other collaborators

Unknown

Ex Vivo Expansion of Circulating Tumor Cells as a Model for Cancer Predictive Pharmacology (EXPEVIVO-CTC)

Melanoma | Circulating Tumor Cell

France
University Hospital, Toulouse

Terminated

Hypothalamic-pituitary Effects After Endoscopic Third Ventriculostomy

Obstructive Hydrocephalus

France
Stony Brook University

Unknown

Collagenase in the Treatment of Cellulite

Cellulite

United States
Burzynski Research Institute

Withdrawn

Antineoplaston Therapy in Treating Patients With Neuroendocrine Tumor That Is Metastatic or Unlikely to Respond to Surgery or Radiation Therapy

Merkel Cell Carcinoma | Neuroendocrine Carcinoma | Pituitary Tumor | Islet Cell Carcinoma

United States
Mannkind Corporation

Completed

Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-MT) for Patients With Melanoma.

Advanced Melanoma | Stage III and IV Melanoma

United States

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