Search clinical trials for: Dabigatran

Total 295 results

Pfizer

Completed

Study of PF-04965842 Effect on Dabigatran Pharmacokinetics in Healthy Participants

Healthy

Belgium
Georg Nickenig
Boehringer Ingelheim

Completed

Prevention of Silent Cerebral Thromboembolism by Oral Anticoagulation With Dabigatran After Pulmonary Vein Isolation for Atrial Fibrillation (ODIn-AF)

Atrial Fibrillation | Oral Anticoagulation | Cardioembolic Events

Germany
Assistance Publique - Hôpitaux de Paris

Completed

Benefit/Risk in Real Life of New Oral Anticoagulants and Vitamin K Antagonists in Patients Aged 80 Years and Over (PRESAGE-ACO)

Atrial Fibrillation

France
Boehringer Ingelheim

Completed

Safety, Pharmacokinetics and Pharmacodynamics After Single Rising Oral Doses of BIBR 1048 MS as Capsules in Healthy Subjects of Japanese and Caucasian Origin

Healthy
Medical University of Vienna

Completed

Antithrombotic Triple Therapy in Humans

Atrial Fibrillation | Acute Coronary Syndrome

Austria
University of Sao Paulo General Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Effects of Low Molecular Weight Heparin Versus Dabigatran on Platelet Aggregation in Patients With Stable Coronary Artery Disease

Coronary Disease

Brazil
Boehringer Ingelheim

Completed

Bioavailability of BIBR 953 ZW Under Influence of Food in Healthy Subjects

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BIBR 953 ZW After BIBR 1048 (Oral Pro-drug of BIBR 953 ZW) Administered as Hydroxypropyl Methylcellulose (HPMC) Polymorph II Capsule Relative to HPMC Polymorph I Capsule in Healthy Subjects.

Healthy
Deutsches Herzzentrum Muenchen

Terminated

Impact of Dabigatran and Phenprocoumon on Clopidogrel Mediated ADP Induced Platelet Aggregation in Patients With Atrial Fibrillation (Dabi-ADP-2)

Atherosclerosis | Atrial Fibrillation | Coronary Heart Disease | Acute Coronary Syndrome

Germany
Boehringer Ingelheim

Completed

Secondary Prevention of Venous Thrombo Embolism (VTE). (RE-MEDY)

Thromboembolism

United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, China, Czech Republic, Denmark, Finland, France, Germany, Greece, Hungary, India, Israel, Italy, Mexico, Netherlands, New Zealand, Norway, Poland, Portugal, Russian... and more
Ottawa Heart Institute Research Corporation
Bristol-Myers Squibb; Bayer; Boehringer Ingelheim; Heart and Stroke Foundation...

Completed

Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events (BRUISECONTROL2)

Hematoma

Canada, Israel
University of Texas at Austin
University of Kansas

Not yet recruiting

Restart TICrH Alpha Pilot Protocol, Restarting DOACs After Traumatic Intracranial Hemorrhage

Anticoagulants; Increased
Bristol-Myers Squibb

Completed

Real-World Comparative Observational Study in Non-Valvular Atrial Fibrillation Patients Using Oral Anticoagulants

Atrial Fibrillation
Boehringer Ingelheim

Completed

BIBR 1048 Dose Range Finding Study in Prevention of Venous Thromboembolism in Patients With Primary Elective Total Hip or Knee Replacement Surgery

Venous Thromboembolism

Austria, Belgium, Czech Republic, Denmark, Finland, France, Hungary, Italy, Netherlands, Norway, South Africa, Sweden
Boehringer Ingelheim

Completed

Relative Bioavailability of Single Doses of Dabigatran Etexilate in Healthy Volunteers

Healthy
Yokohama City University Medical Center
Yokohama City University

Unknown

Anti-inflammatory Effects of Rivaroxaban Versus Dabigatran (RIVAL-AF)

Atrial Fibrillation

Japan
Boehringer Ingelheim

Completed

Metabolism and Pharmacokinetics of [14C]-BIBR 953 ZW After Administration of Single Doses of [14C]-BIBR 953 ZW Intravenously or [14C]-BIBR 1048 Oral Solution in Healthy Male Volunteers

Healthy
IHF GmbH - Institut für Herzinfarktforschung
OrbusNeich

Withdrawn

COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials (COSTA)

Coronary Disease | Stable Angina | Unstable Angina | STEMI | NSTEMI

Germany
Stéphane Zuily
International Society on Thrombosis and Haemostasis

Recruiting

International Registry of Thrombotic APS Patients Treated With Direct Oral Anticoagulants (OBSTINATE)

Thrombosis | Antiphospholipid Syndrome | Anticoagulants Causing Adverse Effects in Therapeutic Use

France
Fondazione per la Ricerca Ospedale Maggiore

Completed

Use of Direct Oral Anticoagulants (DOACs) in Patients With Ph-negative Myeloproliferative Neoplasms (MPN-DOACs)

Myeloproliferative Neoplasm

Italy, United Kingdom, Germany, France, United States, Spain, Canada
Boehringer Ingelheim

Completed

Bioavailability of BIBR 1048 MS Tablets in Healthy Subjects With or Without Food

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BIBR 1048 MS With and Without Pantoprazole Under Influence of Food in Healthy Subjects

Healthy
Brigham and Women's Hospital

Active, not recruiting

Prospective Monitoring of Non-Vitamin K Oral Anticoagulants in Older Adults With Atrial Fibrillation and Frailty

Stroke | Atrial Fibrillation | Frailty | Anticoagulant-induced Bleeding

United States
Bristol-Myers Squibb

Completed

A Real-World Comparison of Safety and Effectiveness of Novel Oral Anti-Coagulant (NOAC) Naïve and Warfarin Naïve Non-Valvular Atrial Fibrillation (NVAF) Patients With Medicare Advantage Coverage

Atrial Fibrillation
Bayer
Janssen Scientific Affairs, LLC

Completed

Use of Direct Oral Anticoagulants in UK

Stroke

United Kingdom
Bayer
Janssen, LP

Completed

Study to Gather Information About the Safety of Oral Anticoagulation Drugs and How Well These Drugs Work in Real World for Patients With Non-valvular Atrial Fibrillation (Irregularly Heart Beats Which is Not Caused by a Heart Valve Problem) (REATTAIN)

Atrial Fibrillation

Sweden
Mayo Clinic

Terminated

Vascular Boot Warming Program After Acute Deep Vein Thrombosis (DVT) ± Pulmonary Embolism (PE)

Acute DVT of Lower Extremity

United States
Pfizer

Completed

Non-interventional, Retrospective Cohort Study to Explore OAC Treatment in Korea

Atrial Fibrillation

Korea, Republic of
Martini Hospital Groningen

Completed

Safety of DAbigatran and RIvaroxaban Versus NAdroparin in the Prevention of Venous Thromboembolism After Knee Arthroplasty Surgery (DARINA)

Venous Thromboembolism

Netherlands
Peking University Third Hospital

Recruiting

A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients

Chronic Kidney Disease

China
Boehringer Ingelheim

Completed

BIBR 953 ZW in Healthy Elderly Subjects

Healthy
Boehringer Ingelheim

Completed

Safety and Pharmacokinetics of Quinidine Alone and in Combination With Dabigatran Etexilate

Healthy
Boehringer Ingelheim

Completed

Relative Bioavailability of Dabigatran and Atorvastatin in Healthy Male and Female Volunteers

Healthy
University of Florida

Completed

Pharmacodynamic Effects of Dabigatran in Patients on Dual Antiplatelet Therapy

Coronary Artery Disease

United States
Population Health Research Institute
Hamilton Health Sciences Corporation

Recruiting

The Direct Oral Anticoagulation Versus Vitamin K Antagonist After Cardiac Surgery Trial (DANCE)

Bleeding Post Cardiac Surgery | Indication for Anticoagulation

Canada
Fundación de Investigación Biomédica - Hospital...

Active, not recruiting

Predictive Factors for Response to New Oral Anticoagulants in the Treatment of Non-valvular Atrial Fibrillation..

Atrial Fibrillation

Spain
Pfizer

Active, not recruiting

Anticoagulation in Patients With Venous Thromboembolism and Cancer (VICTORIE)

Neoplasms | Embolism

United Kingdom
Pfizer

Completed

Treatment Patterns and Bleeding Risk of Anticoagulants in Patients With Venous Thromboembolism in Korea

Venous Thromboembolism

Korea, Republic of
Medical University of Gdansk
Institute of Cardiology, Warsaw, Poland; Medical University of Silesia; Pomeranian... and other collaborators

Recruiting

Dual Antithrombotic Therapy With Dabigatran and Ticagrelor in Patients With ACS and Non-valvular AF Undergoing PCI (ADONIS-PCI)

Atrial Fibrillation | Acute Coronary Syndrome | Antithrombotic Therapy | Percutaneous Coronary Interventions

Poland
University of Malta
Università degli Studi dell'Insubria

Recruiting

DOAC in Unusual Site Venous Thrombosis (DUST)

Cerebral Vein Thrombosis | Renal Vein Thrombosis | Retinal Vein Thrombosis | Splanchnic Vein Thrombosis | Ovarian Vein Thrombosis

Thailand, Spain, United States, Italy, Slovenia, France, Israel, Canada, Malta, Netherlands
Malmö University
Odontologisk Forskning i Region Skåne (OFRS)

Completed

NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications

Postoperative Complications | Hemorrhage | Anticoagulant-induced Bleeding | Oral Surgical Procedures | Anticoagulants Causing Adverse Effects in Therapeutic Use | Surgery, Oral

Sweden
University of Pavia

Completed

ORal anticoaGulants in diAbetic and Nondiabetic Patients With nOn-valvular Atrial fibrillatioN (ORGANON) (ORGANON)

Diabetes

Italy
Boehringer Ingelheim

Completed

Safety, Pharmacokinetics and Pharmacodynamics of BIBR 1048 MS Capsule in Healthy Male Subjects of Japanese and Caucasian Origin

Healthy
University of Aarhus
Odense University Hospital; Karolinska University Hospital; Oslo University Hospital and other collaborators

Recruiting

Left Atrial Appendage Occlusion Versus Novel Oral Anticoagulation for Stroke Prevention in Atrial Fibrillation (Occlusion-AF)

Stroke | Atrial Fibrillation

Sweden, Finland, Norway, Denmark, Germany
Boehringer Ingelheim

Completed

Tolerability of BIBR 953 ZW IV and Bioavailability of BIBR 1048 Tablet and Solution in Healthy Males

Healthy
Boehringer Ingelheim

Completed

Bioavailability of BIBR 953 ZW in Healthy Subjects

Healthy
Yonsei University

Terminated

Safety and Efficacy of Left Atrial Appendage Closure Versus Antithrombotic Therapy in Patients With Atrial Fibrillation Undergoing Drug-Eluting Stent Implantation Due to Complex Coronary Artery Disease

Coronary Artery Disease | Atrial Fibrillation

Korea, Republic of
AstraZeneca

Completed

Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female Volunteers

Healthy Volunteers

United States
Imperial College London
King's College London; Medical University of Graz; University of Bordeaux; Hospital... and other collaborators

Recruiting

PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation (PRESTIGE-AF)

Atrial Fibrillation | Intracerebral Hemorrhage

United Kingdom, Germany, Spain
Laval University

Withdrawn

DOAC Versus VKA After Cardiac Surgery (DOAC/VKA)

Anticoagulant-induced Bleeding

Canada

3

Subscribe