Search clinical trials for: donor-derived NK cell infusion

Total 1480 results

Precision Biotech Taiwan Corp.
Tri-Service General Hospital

Recruiting

Allogeneic PB103 (NK Cells) Therapy in Non-small Cell Lung Cancer (NSCLC) Patients

Non-small Cell Lung Cancer

Taiwan
Imperial College London

Withdrawn

CD56+CD3- NK Cells Following Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplant | Haematological Malignancies | CD56+CD3- NK Cells

United Kingdom
Martín, José Luis Díez, M.D.

Completed

Efectiveness of Donor IL-15-stimulated NK Cells Post Transplant Infusion in in Acute Leukemia

ACUTE LEUKEMIA

Spain
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS (NKAML)

Adult Acute Myeloid Leukemia in Remission

Italy
Michael Pulsipher, MD
Seattle Children's Hospital; Nationwide Children's Hospital

Enrolling by invitation

Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults With High Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant (EXCEL)

Acute Myeloid Leukemia

United States
Asan Medical Center

Terminated

Randomized Study of Haploidentical Hct and Subsequent Donor nk Cell Infusion in High-risk AML and MDS (DNKI-4)

Acute Myelogenous Leukemia

Korea, Republic of
Angus W. Thomson PhD DSc
University of Pittsburgh

Active, not recruiting

DCreg in Living Donor Liver Transplantation

Living Donor Liver Transplantation

United States
Southwest Hospital, China

Unknown

By Using Adoptive Transfer of Autologous NK Cells to Prevent Recurrence of Hepatocellular Carcinoma After Curative Therapy

Hepatocellular Carcinoma

China
Beijing GoBroad Hospital

Not yet recruiting

CD5 Chimeric Antigen Receptor (CAR) T Cells in Subjects With Relapsed or Refractory T-Cell Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-Cell Acute Lymphocytic Leukemia
American CryoStem Corporation

Active, not recruiting

ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion

Post-Concussion Syndrome

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI); Assisi Foundation

Completed

Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia

Lymphoblastic Leukemia, Acute

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Ministry of Health, Italy

Terminated

Haploidentical Stem Cell Transplant With or Without NK Cell Infusion in AML and MDS (Bigeminy)

Acute Myeloid Leukemia | Myelodysplasia

Italy
Puerta de Hierro University Hospital

Recruiting

Donor-derived Cell Free DNA as a New Biomarker in Cardiac Acute Rejection (FreeDNA-CAR)

Heart Transplant Rejection

Spain
Paris Translational Research Center for Organ Transplantation

Completed

Donor Derived Cell-free DNA and Rejection of Kidney Allografts

Kidney Rejection Transplant
Puerta de Hierro University Hospital

Completed

Potential Role of Donor-derived Cell-Free DNA as a Biomarker in Cardiac Allograft Vasculopathy (FreeDNA-CAV)

Cardiac Allograft Vasculopathy

Spain
Belarusian Research Center for Pediatric Oncology...

Recruiting

Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With AML

Acute Myeloid Leukemia

Belarus
Mitchell Horwitz, MD

Completed

Naive T-Cell Depleted DLI Following Allo Stem Cell Transplant

Hematological Malignancies

United States
Beijing GoBroad Hospital

Recruiting

Autologous and Donor-derived CD7 CAR-T Therapy in Refractory or Relapsed T-cell Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia, in Relapse | Refractory Acute Lymphoblastic Leukemia | T-cell Acute Lymphoblastic Leukemia

China
University College, London
Deutsche Krebshilfe e.V., Bonn (Germany); European Union; The Leukemia and Lymphoma... and other collaborators

Terminated

CD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL) (CD19TPALL)

Acute Lymphoblastic Leukemia

United Kingdom, Germany
Monica Thakar

Completed

Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors (STIR)

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | CNS Tumors

United States
Loma Linda University

Recruiting

Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection

Graft Failure | Acute Rejection of Renal Transplant

United States
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Haploidentical NK Cells After Pemetrexed in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC) (Medi-NK)

Non-small Cell Lung Cancer

Korea, Republic of
A.O. Ospedale Papa Giovanni XXIII

Recruiting

Infusion of Donor Derived Cytokine Induced Killer (CIK) Cells in Hematological Patients Relapsed After Haploidentical Stem Cell Transplant (Haplo-CIK)

Relapsed Hematologic Malignancy

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Engineered NK Cells Containing Deleted TGF-BetaR2 and NR3C1 for the Treatment of Recurrent Glioblastoma

Recurrent Gliosarcoma | Recurrent Supratentorial Glioblastoma | Supratentorial Gliosarcoma

United States
Leiden University Medical Center

Completed

Mesenchymal Stem Cells and Subclinical Rejection (Measure)

Organ Transplantation

Netherlands
LaTonya J. Hickson

Active, not recruiting

Stem Cell Therapy for Chronic Kidney Disease

Diabetes Mellitus, Type 2 | Diabetes Mellitus | Chronic Kidney Diseases | Diabetes Mellitus, Type 1 | Diabetic Nephropathies

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias

Lymphoma | Leukemia

United States
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Beth Israel Deaconess Medical Center; Brigham...

Completed

Donor Dendritic Cells And Donor Lymphocytes in Patients With Relapsed Hematologic Malignancies After Allogeneic Transplant

Hematologic Malignancy

United States
Vastra Gotaland Region
Karolinska University Hospital; Lund University Hospital

Completed

A New Biomarker for the Non-invasive Diagnosis of Rejection After Heart Transplantation (BIODRAFT)

Heart Transplant Rejection

Sweden
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
University of Milan

Active, not recruiting

Next Generation Sequencing to Detect Acute Rejection in Lung Transplant Patients. (NGS-ACRL)

Lung Transplant Rejection

Italy
Chinese PLA General Hospital

Unknown

A Feasibility and Safety Study of Concomitant Therapy With Allo-CAR-T Cells and Allo-HSCT in Patients With Relapse or Refractory Leukemia

B Cell Leukemia

China
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Safety and Efficacy Study of Donor Natural Killer Cells Given After Haploidentical Hematopoietic Cell Transplantation (DNKI-II)

Acute Lymphoblastic Leukemia | Acute Myelogenous Leukemia

Korea, Republic of
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

Korea, Republic of
Peking University People's Hospital

Completed

Preemptive Therapy With CMV-specific T Cells Infusion to Prevent Refractory CMV Infection Post Transplantation

CMV Infection

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Phase I Study of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia | Complete Hematologic Remission (CHR) | Persistent/Recurrent Minimal Residual Disease (MRD)

Italy
Stanford University
University of California, San Francisco

Not yet recruiting

Islet Transplantation With Recipient T-Reg Cells or Deceased Donor Vertebral Bone Marrow Therapy

Islet Transplantation

United States
Murdoch Childrens Research Institute
Sydney Children's Hospitals Network; Monash Health; Cerebral Palsy Alliance; The... and other collaborators

Completed

Stem Cells in Umbilical Blood Infusion for CP (SCUBI-CP)

Cerebral Palsy

Australia
University of Nebraska

Withdrawn

Donor Enriched Activated NK Cell Infusion Post Haploidentical Stem Cell Transplant for Refractory Myeloid Malignancies

Leukemia
National University Hospital, Singapore
Singapore General Hospital

Unknown

T-cell Depleted Donor Lymphocyte Infusion (DLI)for Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Singapore
Sabine Mueller, MD, PhD
Washington University School of Medicine; Nationwide Children's Hospital; Rally...

Not yet recruiting

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Brain Tumors (PNOC028)

Pediatric Brain Tumor | Recurrent Pediatric Brain Tumor | Pediatric Supratentorial Neoplasm

United States
University College, London

Suspended

Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT (CMV_TCR-001)

CMV Infection | Haematological Malignancies

United Kingdom
Nelson Chao

Terminated

Trial of CMV Specific DLIs From 3-6/6 HLA Matched Family Member Following Nonmyeloablative Allo SCT

Cytomegalovirus Infections

United States
Southwest Hospital, China

Unknown

A Clinical Research of NK Cell Infusion Combined With Chemotherapy in the Treatment of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

China
M.D. Anderson Cancer Center
Ziopharm Oncology

Completed

Infusion of Allogeneic CD19-Specific T Cells From Peripheral Blood

Lymphoma | Leukemia

United States
Charite University, Berlin, Germany
University of Leipzig

Unknown

Haploidentical Transplantation With Early Adoptive Transfer of CD56+CD3- NK Cells

Acute Myeloid Leukemias | Advanced Hematological Malignancies | Indication for Allogeneic Stem Cell Transplantation | no HLA-identical Donor Available

Germany
Assistance Publique - Hôpitaux de Paris
Pierre and Marie Curie University; Université Paris XII

Completed

Amplifying Graft-Versus-Tumor Effect by Donor Regulatory T-Cell Depletion Before Donor Lymphocytes Infusion (ILD-Treg)

Hematologic Neoplasms | Relapse

France
Laura Johnston
National Institutes of Health (NIH)

Completed

Phase 1 Infused Donor T Regulatory Cells in Steroid Dependent/Refractory Chronic GVHD

Graft Versus Host Disease | Allogeneic Hematopoietic Cell Transplant Recipient

United States
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis

Neutropenic Enterocolitis | Myeloablative Chemotherapy Induced Bone Marrow Aplasia

Russian Federation
Baptist Health South Florida

Active, not recruiting

T-cell Receptor α/β Depleted Donor Lymphocyte Infusion

Myeloid Malignancy | Lymphoid Leukemia, Acute | Plasma Cell Tumor

United States
Barts & The London NHS Trust
University College, London; Queen Mary University of London

Completed

Bone Marrow Derived Adult Stem Cells for Acute Anterior Myocardial Infarction (REGEN-AMI)

Acute Myocardial Infarction

Switzerland, Denmark, United Kingdom

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