Search clinical trials for: high dose methotrxate

Total 12444 results

Oryzon Genomics S.A.
Alzheimer's Drug Discovery Foundation

Completed

Testing the Safety and Preliminary Efficacy of the New Drug ORY-2001 in Mild to Moderate Alzheimer's Disease (ETHERAL-US)

Mild to Moderate Alzheimer's Disease

United States
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Thomas Jefferson University

Completed

Gluten Ingestion Biomarkers in Patients w Gluten Sensitivity and Healthy Controls Peptides in Patients With Non-celiac Gluten Sensitivity and Healthy Patients: A Placebo-controlled Study (NCGS)

Non Celiac Gluten Sensitivity

United States
AbbVie (prior sponsor, Abbott)

Completed

Efficacy and Safety Study for Cognitive Deficits in Adult Subjects With Schizophrenia

Cognitive Deficits in Schizophrenia

United States
The Hospital for Sick Children

Terminated

Impact of Emergency Department Probiotic Treatment of Diarrheal Illness on Daycare Attendance

Gastroenteritis

Canada
Dennis Charney

Completed

Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers (NPY)

Anxiety Disorders | Mood Disorder

United States
University of Miami

Recruiting

Tfh Dysfunction in HIV and Aging

Human Influenza

United States
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 3, 2011

Influenza
Korean Hemodialysis Study Group
Boryung Pharmaceutical Co., Ltd

Unknown

High Versus Standard Volume Hemodiafiltration in Asia

End-stage Renal Disease

Korea, Republic of
Aclaris Therapeutics, Inc.

Completed

ATI-501 Oral Suspension Compared to Placebo in Subjects With Alopecia Areata, Alopecia Universalis or Alopecia Totalis

Alopecia

United States
Hernando Gomez
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Enrolling by invitation

Safety and Feasibility of Metformin for Sepsis Induced AKI

Sepsis | Septic Shock | Acute Kidney Injury | Metformin

United States
University of Roehampton

Recruiting

The Effect of a Botanical Plant Extract on Gut Health, Immunity and Metabolic Disorders in Healthy Adults (GHIMD)

Healthy

United Kingdom
Institute of Medical Biology, Chinese Academy of...
Guangxi Center for Disease Control and Prevention

Completed

Clinic Trial to Evaluate the Safety and Immunogenicity by Different Sequential Schedules of bOPV and IPV

Poliomyelitis

China
GlaxoSmithKline

Active, not recruiting

Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection

Hepatitis B, Chronic

Taiwan, Belgium, Thailand, Germany, Spain, Hong Kong, United Kingdom, France, Poland
Jiangsu Province Centers for Disease Control and...
Academy of Military Medical Sciences，Academy of Military Sciences，PLA; ZHONGYIANKE... and other collaborators

Recruiting

Phase I Trial of a Recombinant COVID-19 Vaccine (CHO Cell)

COVID-19

China
Mymetics Corporation
Institut Cochin; San Raffaele University Hospital, Italy; Kinesis Pharma B.V.; ... and other collaborators

Completed

Investigation of the Safety of an HIV-1 Vaccine Given Intra-muscularly and Intra-nasally to Healthy Female Subjects

HIV-1

Belgium
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of M5049 in DM and PM Participants (NEPTUNIA)

Dermatomyositis | Polymyositis

United States, Italy, Spain, Greece, Czechia, United Kingdom, Poland
Sylentis, S.A.

Completed

Safety, Tolerability and Pharmacokinetic Profile of SYL1801 Eye Drops

Choroidal Neovascularization | Safety, Tolerability and Pharmacokinetic Profile in Healthy Volunteers

Spain
Société des Produits Nestlé (SPN)

Completed

Growth, Safety and Efficacy of a Probiotic Supplement (Clara)

Probiotic Supplement

Philippines
Jeil Pharmaceutical Co., Ltd.

Unknown

Clinical Trial to Evaluate the Efficacy and Safety of JPI-289 in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke

Korea, Republic of
Frontera Therapeutics

Recruiting

Gene Therapy in Subjects With Biallelic RPE65 Mutation-associated Retinal Dystrophy

Biallelic RPE65 Mutation-associated Retinal Dystrophy

China
Boehringer Ingelheim

Completed

BI 6727 (Volasertib) Monotherapy Phase I Trial in Japanese Patients With Advanced Solid Tumours

Neoplasms

Japan
Pharnext SA

Completed

Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A

Charcot-Marie-Tooth Disease | Hereditary Neuropathy With Liability to Pressure Palsies | Genetic Disorders

France
GlaxoSmithKline

Completed

GSK618334 Repeat Dose Study

Substance Dependence

United Kingdom
Anhui Medical University

Unknown

Evaluation of the High Dose of Icotinib in Advanced Lung Cancer Patients After Failure of Target Therapy

NSCLC

China
Seoul St. Mary's Hospital

Unknown

Intensity-modulated Radiotherapy Protocol in Cervix Cancer

Radiation

Korea, Republic of
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

T-cell And General Immune Response to Seasonal Influenza Vaccine (SLVP018) Year 2, 2010

Influenza
Kangpu Biopharmaceuticals, Ltd.

Completed

Phase 1b/2a Study to Evaluate Safety and Efficacy of KPG-818 in SLE (Lupus)

SLE; Drug

United States
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of MT-8554 in Female Subjects Experiencing Vasomotor Symptoms

Vasomotor Symptoms

Germany
Medical University of Warsaw

Recruiting

Induction of Sustained Unresponsiveness to Peanuts Using High- and Low-dose Peanut Oral Immunotherapy

Peanut Allergy

Poland
Ohio State University Comprehensive Cancer Center
Varian Medical Systems

Active, not recruiting

Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia (PREVENT)

Pneumonia | Covid-19 | Sars-CoV2

United States, Colombia
Beijing Konruns Pharmaceutical Co., Ltd.

Completed

The Effect of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease

Chronic Pelvic Pain

China
Anhui Provincial Hospital

Recruiting

Hypofraction Radiotherapy for Limited-Stage Small Cell Lung Cancer

Safety Issues | Efficacy, Self

China
University Hospital, Lille

Recruiting

Utility of Sodium Lactate Infusion During Septic Shock (ULIS1)

Septic Shock

France
Receptor Life Sciences

Withdrawn

Safety, Tolerability, and Efficacy of RLS103 in Subjects With Acute Anxiety Within Social Anxiety Disorder (SAD)

Social Anxiety Disorder

United States
Medical University of Warsaw

Enrolling by invitation

Induction of Sustained Unresponsiveness to Sesame Using High- and Low-dose Sesame Oral Immunotherapy

Food Allergy

Poland
Peking University Cancer Hospital & Institute

Completed

Different Radiation Dose With Concurrent Chemotherapy for Thoracic Esophageal Carcinoma

Esophageal Cancer

China
Janssen Research & Development, LLC

Completed

A Study of Seltorexant (JNJ-42847922) After Single-Dose Administration in Healthy Participants

Healthy

United States
Genrix (Shanghai) Biopharmaceutical Co., Ltd.

Recruiting

Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE

Lupus Erythematosus, Systemic

China
Visterra, Inc.

Completed

Safety and Efficacy Study of VIS649 for IgA Nephropathy

Immunoglobulin A Nephropathy | Glomerular Disease | IgAN

United States, Australia, Canada, Hong Kong, India, Japan, Korea, Republic of, Malaysia, Philippines, Singapore, Spain, Sri Lanka, Taiwan, Thailand, United Kingdom
RWTH Aachen University
Heinrich-Heine University, Duesseldorf

Withdrawn

Relevance of Flavanols for Cardiovascular Function in End-Stage Renal Disease (ESRD)

End Stage Renal Disease

Germany
Genocea Biosciences, Inc.

Completed

Safety and Immunogenicity Study of Prophylactic Streptococcus Pneumoniae Vaccine

Streptococcus Pneumoniae

United States
KBio Inc

Completed

Study to Evaluate the Safety and Immunogenicity of KBP-V001 Quadrivalent Influenza Vaccine in Healthy Adults

Influenza

United States
Alkermes, Inc.

Completed

A Study of ALKS 9072 in Subjects With Chronic Stable Schizophrenia

Schizophrenia

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Study to Assess the Efficacy, Safety and Tolerability of MT- 8554 in Subjects With Painful Diabetic Peripheral Neuropathy

Painful Diabetic Peripheral Neuropathy

Germany, Hungary, Poland
Jonsson Comprehensive Cancer Center

Recruiting

High Dose-Rate Brachytherapy and Stereotactic Body Radiotherapy for the Treatment of Prostate Adenocarcinoma (HYDRA)

Prostate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IIB Prostate Cancer American Joint Committee on...

United States
Boehringer Ingelheim

Completed

Weekly Intravenous Administrations of BI 836845 in Japanese Patients With Advanced Solid Tumours

Neoplasms

Japan
Weill Medical College of Cornell University

Recruiting

Cryopreservation of Ovarian Tissue

Cancer | Fertility Preservation | Risk of Premature Ovarian Failure

United States
Jiangsu Province Centers for Disease Control and...
Beijing Institute of Biotechnology; Tianjin Cansino Biotechnology Inc

Completed

A Phase I Clinical Trial to Evaluate the Ebola Adenovirus Vector Vaccine (Ad5-EBOV) in Healthy Adults.

Ebola Virus Disease

China
Kolon TissueGene, Inc.

Not yet recruiting

Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease

Degenerative Disc Disease

Search clinical trials for: high dose methotrxate

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