Search clinical trials for: mRNA

Total 825 results

University Medicine Greifswald

Active, not recruiting

Adaptive Immune Response to COVID-19 Vaccination (AICOVI)

SARS-CoV-2 Vaccination

Germany
Bayer
CureVac

Withdrawn

COVID-19: A Trial Studying the SARS-CoV-2 mRNA Vaccine CVnCoV to Learn About the Immune Response, the Safety, and the Degree of Typical Vaccination Reactions When CVnCoV is Given at the Same Time as a Flu Vaccine Compared to When the Vaccines Are Separately Given in Adults 60 Years of Age and Older (CV-NCOV-011)

Coronavirus Disease 2019 (COVID-19) | SARS-CoV-2 Infection
Assistance Publique - Hôpitaux de Paris
Recherche Clinique Paris Descartes Necker Cochin Sainte Anne; AFM-Téléthon...

Recruiting

Venous Thromboembolism in Myotonic Dystrophy Type 1 (DM1-VTE)

Myotonic Dystrophy 1

France
University Hospital, Basel, Switzerland

Not yet recruiting

Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis (endoMB)

Infertility, Female | Non Specific Chronic Endometritis

Switzerland
University Hospital Ostrava
University Hospital Olomouc; University of Ostrava; Palacky University; Technical...

Completed

Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

Sepsis | Septic Shock | Acute Kidney Injury

Czechia
University of Calgary
Ortho Biotech, Inc.; Calgary Health Region

Completed

The Erythropoietin NeuroProtective Effect: Assessment in CABG Surgery (TENPEAKS)

Brain Injury | Cardiac Surgery

Canada
Qilu Hospital of Shandong University
Chinese PLA General Hospital; Xuanwu Hospital, Beijing; Shenzhen People's Hospital and other collaborators

Not yet recruiting

Evaluation of Vascular Structure in Elderly Using High-frequency Ultrasound and Construction of a Multimodal Risk Assessment System for Cardiovascular Diseases: a Multicenter Study

Stroke | Coronary Disease | Atherosclerosis

China
Beni-Suef University

Completed

Impact of Transforaminal Epidural Steroid Injection in Lumbar Disc Prolpse on Micro RNA-155 Serum Level

Lumbar Disc Herniation

Egypt
Wangluowei

Active, not recruiting

Changhai Multimodal Esophageal Cancer Cohort (CMECC)

Esophageal Squamous Cell Carcinoma

China
Imperial College London
Royal Free Hospital NHS Foundation Trust; Royal Surrey County Hospital NHS...

Completed

MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers (MIRABILE)

Pancreatic Cancer | Cholangiocarcinoma | Biliary Stricture | Gallstone Disease | Ampullary Cancer

United Kingdom
King Fahad Specialist Hospital Dammam

Unknown

Safe Return to Regular Clinical Operation After COVID-19 Pandemic

COVID 19

Saudi Arabia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Biomarkers in Samples From Patients With Rhabdomyosarcoma

Sarcoma
Qihan Li

Not yet recruiting

Study of Ameliorating Effect of COVID-19 mRNA Vaccine in Individuals Immunized With Inactivated Vaccine (COVID-19)

SARS-CoV-2 Acute Respiratory Disease
National Institute of Allergy and Infectious Diseases...
Johns Hopkins University; PPD

Active, not recruiting

COVID Protection After Transplant-Immunosuppression Reduction (CPAT-ISR)

Liver Transplant Recipients | Kidney Transplant Recipients

United States
CNBG-Virogin Biotech (Shanghai) Ltd.

Recruiting

A PhaseⅡ Study to Evaluate the Safety and Immunogenicity of COVID-19 Vaccine

SARS-CoV-2 Infection

China
Vertex Pharmaceuticals Incorporated
Moderna, Inc

Recruiting

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

Cystic Fibrosis

United States, United Kingdom, Australia, Canada
Johns Hopkins University
Integrated Research Center for Fetal Medicine

Recruiting

The Impact of COVID-19 on Maternal and Neonatal Outcomes

COVID-19 | Pregnancy; Infection

United States
jianming xu
NeoCura

Recruiting

Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer, Esophageal Cancer and Liver Cancer

Gastric Cancer | Esophageal Cancer | Liver Cancer

China
University of Florida
The V Foundation for Cancer Research

Not yet recruiting

Study of RNA-lipid Particle (RNA-LP) Vaccines for Recurrent Pulmonary Osteosarcoma (OSA)

Pulmonary Osteosarcoma
Universitair Ziekenhuis Brussel
Marguerite - Marie Delacroix Foundation

Not yet recruiting

Combining Exome and Transcriptome Data to Unravel the Genetic Basis of the Lissencephalies

Classical Lissencephalies and Subcortical Band Heterotopias

Belgium
Public Health Service of Amsterdam
ZonMw: The Netherlands Organisation for Health Research and Development; Amsterdam... and other collaborators

Recruiting

Interventions to Curb Hepatitis C Reinfections Among Men Who Have Sex With Men (ICECREAM)

Hepatitis C Virus Infection

Netherlands, France
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC

Terminated

Biomarkers in Blood Samples From Patients With HIV Infection and Stage III or Stage IV Hodgkin Lymphoma Undergoing Chemotherapy

Lymphoma | Nonneoplastic Condition

United States
University Hospital, Grenoble

Completed

Prognosis Assessment of the Increase of GADD34 Gene Expression for Patient Suffering From Systemic Lupus Erythematosus (GADD34-LES)

Lupus Erythematosus

France
National University of Singapore

Completed

Art Therapy and Music Reminiscence Activity in the Prevention of Cognitive Decline

Mild Cognitive Impairment

Singapore
University of Toronto
University Health Network, Toronto

Terminated

Study of Tumor RNA Disruption Assay™ (RDA) (RnaDx)

Breast Neoplasms

Canada
University of Nottingham

Unknown

Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome

Reversible Cerebral Vasoconstriction Syndrome

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying RNA in Samples From Younger Patients With T-Cell Acute Lymphoblastic Leukemia

Leukemia
University of Bari Aldo Moro

Not yet recruiting

Rapid De-escalation of Anti-MRSA Therapy Guided by S. Aureus Nares Screening in Case of Pneumonia (SNAP)

Pneumonia, Bacterial
Hasselt University

Unknown

Evaluation of the Use of the GenXpert to Detect Hepatitis C RNA

Hepatitis C | Drug Use

Belgium
National Center for Research Resources (NCRR)
Duke University

Unknown

A Safety and Feasibility Study of Active Immunotherapy in Patients With Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed With Antigen Encoded in Amplified Autologous Tumor RNA

Prostate Cancer

United States
Yeditepe University

Recruiting

MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes

To Determine the Levels of miRNA1 and miRNA133a Before and After Exercise

Turkey
Cairo University

Completed

The Senstivity and Specificity of Using Salivary miRNAs in Detection of Malignant Transformation of Oral Lesions.

Oral Premalignant Lesions

Egypt
University of Alabama at Birmingham
ViraCor Laboratories

Withdrawn

COVID Vaccine Immunity in Kidney Transplant Recipients

End Stage Renal Disease | Kidney Transplant; Complications
BioNTech Cell & Gene Therapies GmbH

Recruiting

A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors

Solid Tumor

Australia, Germany, Netherlands, Sweden
University of California, Irvine
Agency for Healthcare Research and Quality (AHRQ)

Completed

Project CLEAR - Changing Lives by Eradicating Antibiotic Resistance (CLEAR)

Methicillin-resistant Staphylococcus Aureus

United States
Applied Science Private University

Completed

Variations in the Composition of Respiratory Microbiota

Asthma

Jordan
National Institute of Allergy and Infectious Diseases...

Recruiting

A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults

Influenza

United States
AZ Sint-Jan AV

Not yet recruiting

D-Dimer-based Indication for Transesophageal Echocardiography to Exclude Left Atrial Thrombus Before Cardioversion of Non-anticoagulated Atrial Fibrillation: A Multicenter Belgian Study (CARDDI-BEL)

Atrial Fibrillation
ModernaTX, Inc.
Aetion, Inc.

Active, not recruiting

Post-marketing Safety of Elasomeran/Davesomeran and Andusomeran

SARS-CoV-2

United States
Sinocelltech Ltd.

Withdrawn

A Study to Evaluate the Immunogenicity and Safety of SCTV01C and SCTV01E (Two Recombinant Protein COVID-19 Vaccines) in Population Aged ≥12 Years

COVID-19 | SARS-CoV-2 Infection
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Study of Adjuvant V940 and Pembrolizumab in Renal Cell Carcinoma (V940-004)

Renal Cell Carcinoma

Australia, United States, Canada, Chile, Taiwan, Argentina
Merck Sharp & Dohme LLC
ModernaTX, Inc.

Recruiting

A Study of V940 Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002) (INTerpath-002)

Non-small Cell Lung Cancer

Poland, United States, New Zealand, Australia, Costa Rica, Taiwan, Argentina, France, Chile, Hungary, Spain, Greece, Canada, Lithuania, Norway, Italy, Czechia, Estonia, Portugal
Norwegian School of Sport Sciences
King's College London; Oslo University Hospital; Rigshospitalet, Denmark; University... and other collaborators

Terminated

Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose

Prostate Cancer | Resistance Exercise | Androgen Deprivation Therapy

Norway
Centre Hospitalier Universitaire Dijon

Unknown

Analysis of Transposon Control Pathways in Germinal Cancers of the Testicle (SEMINOMES)

Germinal Cancers of the Testicle

France
Sohag University

Recruiting

Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP) (microRNAITP)

Primary Immune Thrombocytopenia

Egypt
Royal Marsden NHS Foundation Trust

Recruiting

ORganoid GeneratioN Study for Cancer (ORIGINS)

Cancer

United Kingdom
Research Center Borstel
Ludwig-Maximilians - University of Munich

Terminated

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Bacterial Infections | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Mycobacterial Infection

Germany, Moldova, Republic of, Romania, Ukraine
University of Pennsylvania

Terminated

Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET)

Breast Cancer | Malignant Melanoma

United States
Tufts Medical Center
Hoffmann-La Roche

Terminated

Single Patient Use of Tocilizumab in Systemic Onset Juvenile Idiopathic Arthritis

Arthritis, Juvenile Rheumatoid | Still's Disease, Juvenile Onset

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Expression in Predicting Outcome in Samples From Patients With High-Risk Neuroblastoma

Neuroblastoma

Search clinical trials for: mRNA

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