Search clinical trials for: mRNA-4157

Total 874 results

Dart NeuroScience, LLC

Completed

Pharmacokinetics - Pharmacodynamic Study of HT-2157 in Healthy Subjects and in Patients With Major Depressive Disorder

Healthy Volunteers (Part 1) | Major Depressive Disorder (Part 2)

United States
ModernaTX, Inc.

Active, not recruiting

A Safety, Tolerability, and Immunogenicity Study of mRNA-1345 and mRNA-1365 in Participants Aged 5 Months to <24 Months

Respiratory Syncytial Virus | Human Metapneumovirus

Spain, United Kingdom, Canada, Australia, United States, South Africa, Poland, Colombia, Argentina, Latvia, Panama
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥50 Years of Age (RSVictory)

Respiratory Syncytial Virus

United States
ModernaTX, Inc.

Recruiting

Study to Investigate Safety and Tolerability of mRNA-0184 Administered at 2 Different Infusion Durations in Healthy Participants

Healthy Participants

Australia
ModernaTX, Inc.

Recruiting

A Long-Term Extension Study to Evaluate the Safety and Clinical Activity of mRNA-3927

Propionic Acidemia

United States, Canada, United Kingdom
ModernaTX, Inc.

Recruiting

A Study of mRNA-3745 in Adult and Pediatric Participants With Glycogen Storage Disease Type 1a (GSD1a)

Glycogen Storage Disease

United States, Canada
ModernaTX, Inc.

Withdrawn

Open Label Study of mRNA-3704 in Patients With Isolated Methylmalonic Acidemia

Metabolism, Inborn Errors | Methylmalonic Acidemia (MMA)
Shanghai Jiao Tong University School of Medicine

Recruiting

Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)

Medullary Thyroid Cancer | Pancreatic Neuroendocrine Tumor | Adrenal Cortical Carcinoma | Thymic Neuroendocrine Carcinoma

China
Universitaire Ziekenhuizen KU Leuven
University of Melbourne

Unknown

Development of Potential Biomarkers for Foetal Brain Development After Congenital CMV Infection

Cytomegalovirus Infections | Neurologic Dysfunction
Centocor, Inc.

Completed

A Phase 1 Study of CNTO 3157 in Healthy Volunteers and Patients With Asthma

Asthma

Germany, United Kingdom, Belgium
ModernaTX, Inc.

Completed

A Study of mRNA-1020 and mRNA-1030 Seasonal Influenza Vaccines in Healthy Adults

Seasonal Influenza

United States
Erasmus Medical Center
University Medical Center Groningen; Academisch Medisch Centrum - Universiteit... and other collaborators

Active, not recruiting

SWITCH ON: Analysing the Immunogenicity of Additional Booster Vaccinations in HCW (SWITCHON)

Covid-19 Vaccination

Netherlands
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure

Chronic Heart Failure

United States, United Kingdom, Poland
Sheba Medical Center
ModernaTX, Inc.

Completed

Safety and Immunogenicity of Omicron Variant-Matched Vaccine Booster in Adults (SH-MO-214)

COVID-19 | SARS CoV 2 Infection | COVID-19 Pandemic | Immunogenicity

Israel
Seqirus

Active, not recruiting

Safety, Reactogenicity, and Immunogenicity Study of a Self-Amplifying mRNA Influenza Vaccine in Healthy Adults

Influenza, Human

Australia
University Hospital Tuebingen

Completed

Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma Patients

Malignant Melanoma

Germany
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Pilot Study of a Dendritic Cell Vaccine in HIV-1 Infected Subjects (PARC002)

HIV Infections | HIV-1 Infection

United States
Aveta Biomics, Inc.

Recruiting

Safety and Efficacy of APG-157 in Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of Oral Cavity

United States
Otsuka Pharmaceutical Co., Ltd.

Recruiting

Safety and Efficacy Study of OPC-415 in Patients With Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma (MM)

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating PAZ-417 in Healthy Young/Elderly

Alzheimer Disease

United States
GlaxoSmithKline

Active, not recruiting

A Safety and Immune Response Study to Evaluate Varying Doses of an mRNA Vaccine Against Coronavirus Disease 2019 (COVID-19) in Healthy Adults

COVID-19

United States
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age

Lyme Disease

United States
Lion TCR Pte. Ltd.

Recruiting

Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV) (SAFE-T-HBV)

Hepatocellular Carcinoma

Singapore
Janssen Research & Development, LLC

Completed

A Study of CNTO 3157 in Healthy Normal and Asthmatic Participants Inoculated With Human Rhinovirus Type 16

Healthy Volunteers and Asthma

United Kingdom, Canada, Netherlands, Germany, Denmark, Belgium
Horizon Therapeutics Ireland DAC

Completed

Study to Evaluate HZN-457 in Healthy Volunteers

Healthy

New Zealand
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

Study Evaluating PAZ-417 in Cerebrospinal Fluid in Subjects With Alzheimer's Disease

Alzheimer Disease

United States
ModernaTX, Inc.

Recruiting

A Study to Investigate the Immunogenicity and Safety of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in High-risk Adults

Respiratory Syncytial Virus

Canada, United States, United Kingdom, Puerto Rico
Rigshospitalet, Denmark
Innovation Fund Denmark; Ministry of Education, Denmark

Recruiting

Myopericarditis After Messenger Ribonucleic Acid (mRNA) COVID-19 Vaccination in Children 5-11 Years Old

Myocarditis | SARS-CoV2 Infection | Myopericarditis | Vaccination; Complications | COVID-19 Pandemic

Denmark
ModernaTX, Inc.

Completed

A Study to Evaluate Safety and Immunogenicity of mRNA-1273 Vaccine to Prevent COVID-19 in Adult Organ Transplant Recipients and in Healthy Adult Participants

SARS-CoV-2

United States
National Cancer Institute (NCI)

Completed

A Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants With Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants With Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Boost...

Lymphoma | Leukemia | Multiple Myeloma | Hematologic Malignancy | Solid Tumor Malignancy

United States
Nova Scotia Health Authority
Obafemi Awolowo University

Not yet recruiting

Molecular Subtyping of Triple-negative Breast Cancer and African Ancestry-related Immunogenicity

Triple Negative Breast Cancer
Tang-Du Hospital
Air Force Military Medical University, China

Not yet recruiting

Exosome-based Nanoplatform for Ldlr mRNA Delivery in FH (ENDFH)

Familial Hypercholesterolemia

China
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Immunogenecity and Safety of VaccinemRNA-1273 in Elderly Volunteers (Over 65 y) Compared to Younger Ones (18-45y) (CoviCompareM)

Prevention of COVID19
ModernaTX, Inc.

Active, not recruiting

A Study of the Effectiveness of Moderna COVID-19 Vaccine

COVID-19 | SARS-CoV-2

United States
Maria Joyera Rodríguez

Withdrawn

Study About the Response to the Administration of a Third Dose of mRNA-1273 Vaccine (COVID-19 Vaccine Moderna) in Renal Transplants With Immunological Failure Initial to Vaccination (VAX-TRES)

Covid19
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating the Safety, Tolerability and Activity of One Dose of PAZ-417 Given to Healthy Japanese Subjects

Healthy | Alzheimer Disease

Japan
National Institute of Allergy and Infectious Diseases...

Completed

Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) After Receipt of EUA Vaccines

COVID-19

United States
Elizabeth J Franzmann
Aveta Biomics, Inc.

Recruiting

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Oropharyngeal Dysplasia | Oral Cavity Dysplasia | Oral Carcinoma in Situ

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Terminated

A Study of the Safety of PAZ-417 in Healthy Elderly Adults

Healthy

United States
National Institute of Allergy and Infectious Diseases...
Moderna TX, Inc

Active, not recruiting

Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults

Nipah Virus Infection

United States
National Institute of Allergy and Infectious Diseases...
ModernaTX, Inc.

Completed

Safety and Immunogenicity Study of 2019-nCoV Vaccine (mRNA-1273) for Prophylaxis of SARS-CoV-2 Infection (COVID-19)

COVID-19 | COVID-19 Immunisation

United States
ModernaTX, Inc.

Enrolling by invitation

A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine

Cytomegalovirus Infection

United States
H. Lee Moffitt Cancer Center and Research Institute
ModernaTX, Inc.

Completed

COVID-19 Immunogenicity of a Third Dose of mRNA-1273 Vaccine Among Cancer Patients

Covid19 | SARS-CoV2 Infection

United States
Radboud University Medical Center
Rotterdam Eye Hospital

Terminated

Messenger Ribonucleic Acid (mRNA) Transfected Dendritic Cell Vaccination in High Risk Uveal Melanoma Patients

Uveal Melanoma

Netherlands
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

Anti-cancer Neoantigen mRNA Vaccine to Treat Solid Tumors

Solid Tumor, Adult
ModernaTX, Inc.

Recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Allogenic Hematopoietic Cell Transplantation (HCT) Participants.

Cytomegalovirus Infection

United States
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Cytomegalovirus Infection

United States, Australia, Canada, France, Belgium, Germany, Israel, Italy, United Kingdom, Spain, Estonia, Finland, Japan
ModernaTX, Inc.
National Institute of Allergy and Infectious Diseases (NIAID); Biomedical Advanced...

Completed

A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19

SARS-CoV-2

United States
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Children 2 to <18 Years of Age at High Risk of Respiratory Syncytial Virus

Respiratory Syncytial Virus

United States, Panama
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥60 Years of Age

Respiratory Syncytial Virus

United States, Spain, Taiwan, Korea, Republic of, Singapore, Canada, Belgium, Finland, Japan, United Kingdom, Chile, New Zealand, South Africa, Australia, Puerto Rico, Argentina, Costa Rica, Poland, Bangladesh, Colombia, Germany, ... and more

Search clinical trials for: mRNA-4157

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