Search clinical trials for: matching placebo twice daily (BID)

Total 2354 results

Garden of Life, LLC
Validcare, LLC

Active, not recruiting

Garden of Life Once Daily Women's Probiotic: Vaginal pH and Quality of Life Study

Vaginal Health

United States
The George Institute
National Health and Medical Research Council, Australia

Completed

Theophylline and Steroids in Chronic Obstructive Pulmonary Disease (COPD) Study (TASCS)

Chronic Obstructive Pulmonary Disease

Australia
Shanghai Pharmaceuticals Holding Co., Ltd

Recruiting

Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease

Diabetic Kidney Disease

China
Tel-Aviv Sourasky Medical Center
Tel Aviv Medical Center

Completed

Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine

Coronary Heart Disease | GI Bleeding

Israel
Khon Kaen University
National Research Council of Thailand

Completed

Once-Daily Amikacin Plus Cloxacillin in Febrile Neutropenic Children

Cancer | Neutropenia | Fever
AstraZeneca

Recruiting

A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK (ZEAL UNLOCK)

Liver Cirrhosis

Italy, Japan, Germany, Belgium, Poland, Australia, United States, United Kingdom, Czechia, Slovakia
Sunovion Respiratory Development Inc.

Completed

Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-3)

COPD

United States
Boehringer Ingelheim

Not yet recruiting

A Study in Healthy Men to Test How Well Different Doses of BI 3731579 Are Tolerated

Healthy
Boehringer Ingelheim

Recruiting

A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight

Obesity | Overweight

China
Karyopharm Therapeutics Inc
GOG Foundation; European Network of Gynaecological Oncological Trial Groups... and other collaborators

Recruiting

Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma (XPORT-EC-042)

Endometrial Cancer

United States, Belgium, Spain, Israel, Australia, Italy, Georgia, Ireland, Greece, Germany, Czechia, Slovakia, Canada, Hungary
Salubris Biotherapeutics Inc

Completed

Study of JK07 in Subjects With Heart Failure With Reduced Ejection Fraction (HFrEF)

Heart Failure With Reduced Ejection Fraction

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Safety and Efficacy Study of Centanafadine Sustained-Release (CTN SR) in Adults With Attention-Deficit Hyperactivity Disorder (ADHD)

Attention Deficit Disorder With Hyperactivity

United States
Bristol-Myers Squibb

Completed

A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes

Diabetes Mellitus Type 2

United States, Canada
Bristol-Myers Squibb

Completed

Japanese Phase 1 Multiple Ascending Dose Study

Type 2 Diabetes Mellitus

Japan
Abbott

Completed

A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-384 in Elderly Subjects

Healthy

United States
Myrexis Inc.

Completed

Phase 2 Safety and Efficacy Study of Bevirimat Functional Monotherapy in HIV Treatment-Experienced Patients for 2 Weeks*

HIV Infections

United States
Janssen Pharmaceutica N.V., Belgium

Completed

Abiraterone With Different Steroid Regimens for Side Effect Related to Mineralcorticoid Excess Prevention in Prostate Cancer Prior to Chemotherapy

Prostate Cancer

United Kingdom, Belgium, Hungary, Germany
Hennepin Healthcare Research Institute

Completed

Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial (LIFE-HIV)

Fibrosis | Inflammation

United States
Inmune Bio, Inc.

Recruiting

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation (MINDFuL)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment

Australia, Canada, United Kingdom, Poland, Germany
Cellceutix Corporation

Completed

Efficacy and Safety of Prurisol Administered Orally for Active Mild to Moderate Chronic Plaque Psoriasis

Plaque Psoriasis

United States
PharmaKing

Completed

Efficacy and Safety of MG in the Patients With Alcoholic Fatty Liver Disease and Alcoholic Hepatitis

Alcoholic Hepatitis | Alcoholic Fatty Liver Disease

Korea, Republic of
AbbVie

Recruiting

A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) With Episodic Migraine (Kaleidoscope)

Episodic Migraine

United States, Puerto Rico, Spain, Canada, Netherlands, Israel, Sweden, Poland, Hungary, France, Denmark, Japan, United Kingdom, Italy, Romania, Belgium
Regeneron Pharmaceuticals

Active, not recruiting

A Study to See How Safe and Tolerable Different Doses of REGN13335 Are When Administered Intravenously (IV) or Subcutaneously (SC) to Healthy Adult Participants

Healthy Volunteers

New Zealand
Syneos Health

Completed

First-in-Human Study of SRT-015 in Healthy Subjects.

Nonalcoholic Steatohepatitis

Australia
Sironax USA, Inc.

Completed

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

Corona Virus Infection

Pakistan, United States, Mexico
Bristol-Myers Squibb

Completed

Safety and Efficacy of a Lysophosphatidic Acid Receptor Antagonist in Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

United States, Mexico, Australia, Colombia, Chile, Peru
Bristol-Myers Squibb

Terminated

Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and Diabetic Kidney Disease

Diabetic Kidney Disease

United States, Canada, Denmark, France
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study to Evaluate MT-6548 in Hemodialysis Subjects Currently Receiving ESAs With Anemia Associated With Chronic Kidney Disease in Japan

Anemia; Hemodialysis Dependent Chronic Kidney Disease

Japan
Helwan University

Completed

Efficacy and Tolerability of Lubiprostone in Patients With Nonalcoholic Fatty Liver Disease

NAFLD

Egypt
CollaGenex Pharmaceuticals

Completed

Determine the Effect of Administering Periostat(R) Twice Daily on Patients With Acne Rosacea

Acne Rosacea

United States
Pfizer

Terminated

Efficacy, Safety and Tolerability of PF-06649751 in Parkinson's Disease Patients at Early Stage of the Disease

Parkinson Disease

United States, France, Israel, Germany
Nektar Therapeutics

Completed

Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain (SUMMIT-07)

Low Back Pain | Chronic Pain

United States
QuatRx Pharmaceuticals Company

Completed

Safety and Efficacy Study of Two Dose Regimens of Becocalcidiol in the Treatment of Plaque-Type Psoriasis

Psoriasis

United States
Tempest Therapeutics

Active, not recruiting

Phase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid Tumors

Colorectal Cancer | Solid Tumor | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of Head and Neck | Endometrial Cancer | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Solid Tumors With PIK3Ca Mutation

United States
Universidad del Valle, Colombia
University College, London; Fundación Cardiovascular de Colombia; Fundación FES; Instituto Nacional de Salud

Completed

Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases

Pregnancy | Exercise | Preeclampsia | Micronutrients

Colombia
GlaxoSmithKline

Completed

A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)

Pain, Inflammatory

United Kingdom, Germany, Poland
Kezar Life Sciences, Inc.

Recruiting

A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE)

Lupus Nephritis

United States, Korea, Republic of, Australia, Malaysia, Taiwan, South Africa, China, Singapore, United Kingdom, Puerto Rico, Croatia, India, Greece, Spain, Brazil, Philippines, Guatemala, Argentina, Portugal, Colombia
Tulane University Health Sciences Center

Completed

Trichomonas Vaginalis Repeat Infections Among HIV Negative Women

Vaginitis Trichomonal or Due to Trichomonas

United States
Boehringer Ingelheim

Completed

Safety, Tolerability and Pharmacokinetics of Multiple Rising Doses of BI 113608 in Healthy Male Volunteers

Healthy

Germany
Waterstone Pharmaceutical (Wuhan) Co., LTD.

Recruiting

A Study to Evaluate the Safety and Efficacy of WS016 in Patients With Hyperkalemia.

Hyperkalemia

China
Sunshine Lake Pharma Co., Ltd.

Not yet recruiting

The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder

Depressive Disorder, Major
Regeneron Pharmaceuticals

Terminated

A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

Allergic Rhinitis Due to Cat Allergy

United States, Belgium, Germany, Poland, Canada, France
Regeneron Pharmaceuticals

Terminated

A Study to Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD) (LEAP)

Familial Partial Lipodystrophy | Metabolic Abnormalities

United States, France, Spain, Turkey
Theravance Biopharma
GlaxoSmithKline

Completed

Succinate Salt Version of GSK961081 for Healthy Volunteers

Pulmonary Disease, Chronic Obstructive

United Kingdom
AnGes USA, Inc.

Terminated

Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia (AGILITY)

Critical Limb Ischemia

United States, France, Belgium, Canada, Poland, Finland, Denmark, Netherlands, Hungary, Italy, Sweden
Vyne Therapeutics Inc.

Completed

Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Plaque Psoriasis

Psoriasis | Pruritus

United States
Hennepin Healthcare Research Institute

Completed

Targeted Anticoagulation Therapy to Reduce Inflammation and Cellular Activation in Long-term HIV Disease (TACTICAL-HIV)

HIV Infection | Inflammation | Coagulation

United States
Dirk Fischer

Completed

L-Citrulline in Patients With Post-Polio Syndrome

Post-Polio Syndrome

Switzerland
Bayer

Completed

Imaging Study to Compare Effects of Darolutamide and Enzalutamide With Respect to Placebo on the Blood Flow in the Brain in Healthy Male Volunteers.

Cerebrovascular Circulation

United Kingdom
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy.

Non-small Cell Lung Cancer

China

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