Search clinical trials for: Metformin

Total 2166 results

Rush University Medical Center
Elsa U. Pardee Foundation

Terminated

DA-EPOCH-Rituximab/Metformin (RM) for Double Hit Lymphoma (DLBCL)

Diffuse Large B-Cell Lymphoma

United States
National Institute of Mental Health (NIMH)

Completed

The Use of Metformin in the Treatment of Antipsychotic-Induced Weight Gain in Schizophrenia (The METS Study) (METS)

Schizophrenia

United States
Celltrion

Completed

A Bioequivalence Study of CT-L01 Compared to Co-administration (ALO 25 mg and MET XR 1,000 mg) in Healthy Volunteers

Healthy

Korea, Republic of
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Metformin Combined With Chemotherapy for Pancreatic Cancer (GEM)

Metastatic Pancreatic Cancer | Locally Advanced Pancreatic Cancer

Netherlands
Takeda

Terminated

Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice

Diabetes Mellitus, Type 2

China, Hong Kong
AstraZeneca

Completed

A Study Assessing Saxagliptin Treatment in Type 2 Diabetic Subjects Who Are Not Controlled With TZD Therapy Alone

Diabetes Mellitus, Type 2

United States, Argentina, Canada, Puerto Rico, Mexico, Philippines, India, Peru
Ardea Biosciences, Inc.

Completed

Metformin and Furosemide Drug-Drug Interaction Study

Healthy

United States
Lexicon Pharmaceuticals

Completed

A Study to Evaluate the Interaction of LX4211 and Metformin in Healthy Subjects

Type 2 Diabetes Mellitus

United States
University of Auckland, New Zealand
Auckland Medical Research Foundation; Mercia Barnes Trust of the Royal Australian...

Completed

PCOSMIC Trial - PolyCystic Ovary Syndrome, Metformin for Infertility With Clomiphene (PCOSMIC)

Polycystic Ovary Syndrome

New Zealand
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia

Fatigue | Anemia | Weight Loss | Thrombocytopenia | Fever | Refractory Plasma Cell Myeloma | Lymphadenopathy | Refractory Chronic Lymphocytic Leukemia | Recurrent Plasma Cell Myeloma | Splenomegaly | Recurrent Chronic Lymphocytic Leukemia | Lymphocytosis | Night Sweats

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy

Glioblastoma | Gliosarcoma | Supratentorial Glioblastoma

United States
University of California, San Francisco
University of California, San Diego; Northwestern University; University of Illinois... and other collaborators

Completed

Metformin for the Minimization of Geographic Atrophy Progression in Patients With AMD (METforMIN)

Age-Related Macular Degeneration | Geographic Atrophy | Macular Degeneration, Age-Related | Dry Macular Degeneration

United States
University of California, San Diego

Completed

Reach for Health Study: Obesity-related Mechanisms and Mortality in Breast Cancer Survivors

Breast Neoplasms

United States
Merck Sharp & Dohme LLC

Completed

A Study to Assess the Safety, Tolerability and Glucose-Lowering Efficacy of MK-0893 in Participants With Type 2 Diabetes Mellitus (MK-0893-005)

Type 2 Diabetes Mellitus
Emory University

Terminated

Metformin and Congenital Nephrogenic Diabetes Insipidus

Diabetes Insipidus

United States
Gelesis, Inc.

Completed

The Effect of Gelesis100 on the Pharmacokinetics of Metformin

Healthy Overweight Obese

Canada
National Institute on Aging (NIA)

Completed

The Effects of Metformin on Blood Vessel Structure and Function

Hyperglycemia | Hypertension | Obesity | Hypercholesterolemia

United States
University Health Network, Toronto
Bayer

Completed

A Phase I/II Study of Cisplatin and Radiation in Combination With Sorafenib in Cervical Cancer

Cancer of the Cervix

Canada
Grupo Espanol de Investigacion en Sarcomas

Unknown

Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma

Soft Tissue Sarcoma

Spain
Merck Sharp & Dohme LLC

Completed

MK0431A vs. Pioglitazone in Patients With Type 2 Diabetes Mellitus (0431A-066)

Type 2 Diabetes Mellitus
Novo Nordisk A/S

Terminated

Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes

Diabetes Mellitus, Type 2 | Diabetes

China
Handok Inc.

Completed

Efficacy/Safety Study of Amaryl®M 1/500 mg Twice Daily Versus Amaryl® 4 mg Both in Combination With Lantus® in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

Korea, Republic of
Takeda

Completed

Efficacy and Safety of Alogliptin Combined With Metformin in Participants With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Australia, Brazil, Chile, Guatemala, India, Mexico, New Zealand, Peru, South Africa, Czech Republic, Germany, Hungary, Netherlands, Poland, United Kingdom, Argentina
National Center for Research Resources (NCRR)
University of Virginia

Completed

Randomized Study of Decreased Hyperinsulinemia on the Ovulatory Response to Clomiphene Citrate in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Hyperinsulinism

United States, Italy
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes (MANATEE-T1D)

Cardiovascular Diseases | Type 1 Diabetes | Diabetic Kidney Disease | Endothelial Dysfunction | Insulin Sensitivity

United States
Sanofi

Terminated

Efficacy and Safety of Sotagliflozin Versus Placebo in Chinese Patients With Type 2 Diabetes Mellitus Not Adequately Controlled by Metformin With or Without Sulfonylurea

Type 2 Diabetes Mellitus

China
University of Palermo

Completed

Dulaglutide in Diabetic Patients, Relationship Between Arterial Stiffness, Endothelial Function, Clinical and Laboratory Variables

Diabetes Mellitus

Italy
Woman's
Merck Sharp & Dohme LLC

Completed

Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM

Disorder of Glucose Regulation

United States
Yuhan Corporation

Completed

A Phase 1 Clinical Trial to Investigate Pharmacokinetics and Drug Interaction of Crestor and Glucodown OR SR in Healthy Volunteers

Pharmacokinetics and Drug Interaction of Crestor and Glucodown SR

Korea, Republic of
Aichi Gakuin University

Unknown

Effects of Alogliptin on Pancreatic Beta Cell Function

Diabetes Mellitus, Type 2

Japan
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Metformin Hydrochloride and Aspirin in Treating Patients With Hormone-Dependent Prostate Cancer That Has Progressed After Surgery or Radiation Therapy (PRIMA)

Recurrent Prostate Carcinoma | Stage I Prostate Cancer | Stage III Prostate Cancer | Stage IIA Prostate Cancer | Stage IIB Prostate Cancer

United States
Chinese University of Hong Kong
Peking University First Hospital; Obstetrics & Gynecology Hospital of Fudan... and other collaborators

Recruiting

Aspirin Versus Metformin in Pregnancies at High Risk of Preterm Preeclampsia: a 3-arm Randomized Controlled Trial

Preeclampsia

China
Aljazeera Hospital
Cairo University

Completed

Added Value of N Acetyle Cysteine to Clomiphene Citrate in PCO

PCO

Egypt
Centre for Addiction and Mental Health

Recruiting

Metformin for Antipsychotic-induced Weight Gain in Adults With Intellectual Disability (METIDD)

Obesity | Intellectual Disability | Developmental Disability

Canada
Sherief Abd-Elsalam

Recruiting

Impact of P53 and SIRT1 in Type 2 Diabetes

DM

Egypt
Taipei Medical University Hospital
Taipei Medical University

Completed

Clinical Efficacy and Adverse Reactions of Antipsychotic Treatment

Schizophrenia | Metabolic Disturbance | Hyperprolactinemia

Taiwan
Duke University

Terminated

Effects of Metformin and Fish Oil on Treatment With Clozapine

Schizophrenia | Schizo-affective Disorder
Sanofi

Completed

A Study on Safety, Pharmacokinetics and Pharmacodynamics of Lixisenatide in Pediatric Patients With Type 2 Diabetes Mellitus (T2DM)

Type 2 Diabetes Mellitus

Mexico, South Africa, United States, Mauritius, Spain, Turkey
Colorado State University

Completed

Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin

Physical Activity

United States
Dr Anders Ullén
Bayer; Pierre Fabre Laboratories; Nordic Urothelial Cancer Oncology Group

Completed

Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial Tract (VINSOR)

Bladder Cancer | Urothelial Carcinoma | Urethra Cancer | Ureter Cancer | Renal Pelvis Cancer

Denmark, Sweden
University of Arkansas

Terminated

Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth

Colorectal Neoplasms

United States
Fudan University

Terminated

Sorafenib as a Second Line Treatment in Patients With Advanced or Metastatic Gastric Cancer

Gastric Cancer

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

An Endometrial Cancer Chemoprevention Study of Metformin

Gynecology

United States
Nemours Children's Clinic
Thrasher Research Fund

Completed

Study of Serum Markers for Cardiovascular Risk in Obese Youth and Impact of Lifestyle and Medication Intervention

Obesity

United States
Massachusetts General Hospital
Broad Institute; Instituto Carlos Slim de la Salud

Active, not recruiting

Study of Clinical Response to Acute Metformin By Leveraging Evaluations During a Mixed Meal Tolerance Test for Exploring Glycemia and GeneticS (SCRAMBLED EGGS)

Type 2 Diabetes | Genetics | Metabolism

United States
Eli Lilly and Company

Completed

A Study Comparing the Effects and Safety of Dulaglutide With Insulin Glargine in Type 2 Diabetes Mellitus (AWARD-CHN2)

Type 2 Diabetes Mellitus

China, Mexico, Korea, Republic of, Russian Federation
Central South University

Unknown

Metformin for Treatment of Psoriasis Combined With Disorders of Glucose and Lipid Metabolism (MPGLM)

Psoriasis Vulgaris With Metabolic Disorders
University Hospital, Gentofte, Copenhagen
University of Copenhagen

Completed

The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

Glucose Metabolism Disorders

Denmark
Indonesia University

Unknown

Effects of Metformin in Pre-frail Elderly

Pre-frail Elderly

Indonesia
Asan Medical Center
HanAll BioPharma Co., Ltd.

Completed

Clinical Trial to Compare the Pharmacokinetics and Pharmacodynamics After Oral Administration of Glucophage and HL-018

Healthy

Korea, Republic of

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