Search clinical trials for: midazolam,

Total 1084 results

Amgen

Completed

Multiple Ascending Dose Study on Safety, Tolerability, and Pharmacokinetics of AMG 581 in Healthy Subjects or Subjects With Schizophrenia or Schizoaffective (MAD)

Schizophrenia or Schizoaffective Disorder

United States
Pfizer

Completed

Multiple Dose Safety Tolerability, Pharmacokinetics And Midazolam Interaction In Healthy Overweight And Obese Subjects

Diabetes Mellitus Type 2

United States
Assistance Publique - Hôpitaux de Paris

Completed

Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone Fracture (MIDAZODOL)

Fractures

France
Norgine

Completed

Study to Examine the Effect of Ulimorelin on the Pharmacokinetics of Midazolam in Healthy Volunteers

Digestive System Disorders

United Kingdom
AstraZeneca

Completed

Study to Investigate the Safety, Tolerability and Pharmacokinetics of AZD1940

Low Back Pain

Sweden
Assiut University

Completed

Dexmedetomidine Versus Midazolam Added to Ketamine in Pediatric Patients Undergoing Bone Marrow Aspiration and Biopsy

Procedural Sedation and Analgesia During Bone Marrow Aspiration and Biopsy

Egypt
Corcept Therapeutics

Completed

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

Healthy

United States
Mansoura University

Completed

Dexmedetomidine vs. Ketorolac/ Midazolam for Retinal Surgery

Retinal Surgery
Pronova BioPharma

Completed

PRC-4016 (Icosabutate) Phase I Drug-drug Interaction Study

Healthy

United Kingdom
Food and Drug Administration (FDA)
Leiden University; Spaulding Clinical Research LLC

Completed

Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on Ventilation

Hypercapnia | Ventilatory Depression

United States
AstraZeneca
Quintiles, Inc.

Completed

Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer

Solid Tumours

United States
National Cancer Institute, Egypt

Withdrawn

Quadratus Lumborum Block for Percutaneous Nephrostomy (QLB)

Regional Anesthesia Morbidity | Adverse Anesthesia Outcome | Nephrostomy; Complications | Upper Urinary Tract Dilatation and Obstruction

Egypt
SK Life Science, Inc.

Completed

Assess the Influence of Cenobamate on the PK of Cytochrome P450 (CYP) Probe Drugs as a Means of Predicting Drug-drug Interactions

Healthy

United States
Cairo University

Completed

Cardioprotective Effect of Ketamine-dexmeditomidine Versus Fentanyl-midazolam in Open Heart Surgery in Pediatrics

Anesthesia

Egypt
Sanofi

Completed

A Drug to Drug Interaction Study of Sotagliflozin With Midazolam and Metoprolol

Type 2 Diabetes Mellitus

United States
King Khaled Eye Specialist Hospital

Completed

Late Onset Postoperative Nausea and Vomiting

Postoperative Nausea and Vomiting

Saudi Arabia
Drexel University College of Medicine

Completed

Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions

Conscious Sedation Failure During Procedure

United States
AstraZeneca

Completed

AZD2066 Cocktail Study

Chronic Pain

United Kingdom
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Pfizer

Recruiting

A Study to Learn How Different Amounts of the Study Medicine Called PF-07976016 Are Tolerated and Act in The Body in Healthy Adults

Healthy

United States
Boehringer Ingelheim

Completed

A Study in Healthy Men and Women Who Are Either Between 18 - 45 Years or Between 65 - 80 Years to Test How Different Doses of BI 474121 Are Tolerated

Healthy

Germany
BioVersys AG
CRU Hungary Kft

Completed

A Study to Assess Effect of BV100 on the Pharmacokinetics of Midazolam in Healthy Participants

Healthy Volunteers

Hungary
Eli Lilly and Company
Loxo Oncology, Inc.

Completed

A Study of Effects of Selpercatinib (LY3527723) on Midazolam in Healthy Participants

Healthy

United States
Boehringer Ingelheim

Completed

This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 1358894 Affects the Way the Body Breaks Down Midazolam

Healthy

Germany
Paion UK Ltd.
Premier Research Group plc

Completed

Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy

Endoscopy | Procedural Sedation

United States
Sherief Abd-Elsalam

Unknown

Propofol Versus Midazolam for Lower Gastrointestinal Endoscopy

Cirrhosis, Liver

Egypt
Pfizer

Completed

A Phase 1 Study To Characterize The Safety, Tolerability, PK And PK Of Repeat Doses Of PF-06648671 In Healthy Adults And Healthy Elderly Subjects

Healthy Adult Subjects and Healthy Elderly Subjects

Belgium
Melbourne Health

Completed

A Study of Methods to Reduce Anxiety in Preoperative Elective Surgical Patients

Anxiety

Australia
University of Pennsylvania
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Alternative Sedation During Bronchoscopy (DEX)

Sedation

United States
University of Pennsylvania

Recruiting

Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve Blocks

Anxiety | Preoperative Anxiety | Peripheral Nerve Block

United States
Arcus Biosciences, Inc.

Completed

Study to Investigate the Safety, Tolerability, and Pharmacokinetic Profile With Oral AB521 in Healthy Volunteers (ARC-14)

Healthy Participants

Netherlands
Boehringer Ingelheim

Active, not recruiting

A Study to Test Different Doses of BI 1823911 Alone and Combined With Other Medicines in People With Different Types of Advanced Cancer With KRAS Mutation

Solid Tumors, KRAS Mutation

Spain, United Kingdom, United States, Belgium
Orion Corporation, Orion Pharma

Active, not recruiting

Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer (CYPIDES)

Prostate Cancer Metastatic

France, United Kingdom, Finland, United States
Pfizer

Completed

A Study of PF-07258669 In Healthy Adult Participants

Healthy Participants

Belgium
AbbVie

Completed

A Study to Assess the Pharmacokinetics and Safety of Co-administered Oral Galicaftor, Navocaftor, and ABBV-576 in Healthy Adults for the Treatment of Cystic Fibrosis (ABBV-576 DDI)

Healthy Volunteers

United States
Karaman Training and Research Hospital

Completed

Effect of Midazolam Premedication on Mask Ventilation Difficulty

Anesthesia Complication

Turkey
Boehringer Ingelheim

Completed

This Study in Healthy Men Tests How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 705564 Affects the Way the Body Breaks Down Midazolam

Healthy

Germany
Claudia Spies

Completed

Comparison of Lormetazepam and Midazolam Used as Sedatives for Patients That Require Intensive Care

Sedation in Intensive Care Unit Patients

Germany
Eli Lilly and Company

Completed

A Study of LY3295668 Erbumine in Participants With Breast Cancer That Has Spread to Other Parts of the Body

Metastatic Breast Cancer

Belgium, United States
Valley Anesthesiology Consultants
Phoenix Children's Hospital; KindVR

Unknown

Effects of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in Children and Adolescents

Tonsillectomy

United States
Infante, Javier Molina, M.D.

Completed

Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy (MIDAPROP)

Procedural Sedation

Spain
Virginia Commonwealth University

Withdrawn

Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam

Alcoholism | Respiration, Artificial

United States
Jiangsu Kanion Pharmaceutical Co., Ltd

Completed

A Drug-Drug Interaction Study To Investigate The Ginkgolides Meglumine Injection To Alter The Pharmacokinetics Of Midazolam

Pharmacokinetics

China
Subei People's Hospital of Jiangsu Province

Unknown

A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury

Traumatic Brain Injury

China
Benazir Bhutto Hospital, Rawalpindi

Completed

Role of Emotional Freedom Techniques in Reducing Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy (EFT)

Postoperative Nausea and Vomiting

Pakistan
Boehringer Ingelheim

Recruiting

A Study in Healthy People to Test How Well Different Doses of BI 3000202 Are Tolerated and How They Affect the Way the Body Handles Midazolam

Healthy

Belgium
Pfizer

Recruiting

A Study to Understand the Effect of Multiple Ascending Doses of PF-07293893 in Healthy Adult Participants

Healthy Participants

Belgium, United States
Peking Union Medical College Hospital
Beijing Shijitan Hospital, Capital Medical University; Beijing Anzhen Hospital

Recruiting

Remimazolam in the Extraction of Impacted Wisdom Teeth

Dental Anxiety | Sedation Complication | Anterograde Amnesia

China
Pfizer
Arvinas Estrogen Receptor, Inc.

Completed

A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam

Healthy Participants

Belgium
Cukurova University

Completed

Preoperative Anxiolysis With Intravenous Midazolam on Intraoperative Sevoflurane Gas Consumption

Sevoflurane | Midazolam

Turkey

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