Search clinical trials for: naloxone placebo

Total 53906 results

Samjin Pharmaceutical Co., Ltd.

Completed

A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Stroke

Stroke, Acute

Korea, Republic of
University of Minnesota

Completed

Naloxone, Hypoglycemia and Exercise

Diabetes Mellitus, Type 1

United States
Norwegian University of Science and Technology
Oslo University Hospital; St. Olavs Hospital

Completed

Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital (NINA-1)

Overdose | Drug Abuse

Norway
University of Washington

Unknown

Subjective Analgesic Effects of Naloxone and Virtual Reality (Narcan)

Pain

United States
S.L.A. Pharma AG

Completed

Naloxone SR Capsules in Patients With Opioid Induced Constipation

Chronic Pain | Opioid Induced Constipation

Germany, United Kingdom
Trustees of Dartmouth College

Not yet recruiting

The Role of the Opioid System in Placebo Effects on Pain and Social Rejection

Pain | Rejection | Placebo Effect

United States
Judith Feinberg

Unknown

Nasal Naloxone for Narcotic Overdose

Drug Overdose

United States
Indivior Inc.

Completed

Transfer of Subjects From Subutex/Suboxone to RBP-6300

Opioid Related Disorder

Austria, Czech Republic, Germany, Sweden
Dartmouth-Hitchcock Medical Center

Completed

Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

United States
Hospices Civils de Lyon

Completed

Efficacy of Naloxone in Reducing Postictal Central Respiratory Dysfunction in Patients With Epilepsy (ENALEPSY)

Epilepsy

France
Lightlake Sinclair Ltd.

Unknown

Clinical Trial on Binge Eating Disorder, Treatment With Naloxone Spray (BED)

Binge Eating Disorder
Yale University
National Institute on Drug Abuse (NIDA); Howard University; George Mason University

Completed

HIV, Buprenorphine, and the Criminal Justice System (STRIDE)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence

United States
Mundipharma Research GmbH & Co KG

Completed

Optimisation of Hydromorphone - Naloxone Ratio for the Treatment of Pain (HMX3501)

Constipation

Romania, Switzerland, Israel, Belgium, Germany, Australia, Austria, Czech Republic, Denmark, Finland, France, Netherlands, Poland, United Kingdom
mads u werner
University of Kentucky

Completed

Effect of High-dose Naloxone Following Third Molar Extraction (TME)

Pain, Acute | Healthy Subjects | Hyperalgesia | Sensitization, Central | Inflammations, Endodontic

Denmark
Finnish Institute for Health and Welfare

Unknown

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder (NalGamb)

Naloxone | Gambling Disorder | Opioid Antagonist | Pathological Gambling

Finland
Pocket Naloxone Corp

Completed

Pharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy Volunteers

Opioid Overdose

Canada
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
Wayne State University

Completed

Effects of Buprenorphine/Naloxone Dose on Experimental Stress Reactivity and Opioid Abstinence (BOS)

Heroin Dependence | Opioid Use Disorder

United States
Mundipharma Research GmbH & Co KG

Completed

A Randomised, Double Blind, Placebo and Active Controlled, Double Dummy,Parallel Group Study to Determine the Safety and Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Subjects With Moderate to Severe, Chronic Nonmalignant Pain

Subjects With Moderate to Severe, Chronic Nonmalignant Pain
University of Washington
GlaxoSmithKline; Asociación Civil Impacta Salud y Educación, Peru

Completed

HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1, HSV-2 Co-infected Men.

HIV Infection | Sexually Transmitted Diseases | Herpes Simplex

Peru
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray, Naloxone Hydrochloride (HCl) Intravenous (IV) and Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
mads u werner
University of Kentucky

Completed

Effect of High-dose Target-controlled Naloxone Infusion on Pain and Hyperalgesia During a Burn Injury (TCI-NX-BI)

Healthy Subjects

Denmark
Rigshospitalet, Denmark

Completed

Effect of High Dose Naloxone on Secondary Hyperalgesia

Pain | Naloxone | Hyperalgesia | Opioid Antagonist

Denmark
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA)

Recruiting

Efficacy of Buprenorphine and XR-Naltrexone Combination for Relapse Prevention in Opioid Use Disorder (COMBO)

Opioid-use Disorder

United States
INSYS Therapeutics Inc

Completed

A Study to Compare Bioavailability of Naloxone Nasal Spray and Naloxone Hydrochloride (HCl) Intramuscular Injection (IM) in Healthy Volunteers

Healthy Volunteer

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
Leiden University Medical Center
U.S. Food and Drug Administration (FDA)

Recruiting

Reversal of Opioid-induced Respiratory Depression With Opioid Antagonists (ROAR)

Chronic Opioid Use | Opioid Induced Respiratory Depression

Netherlands
Rigshospitalet, Denmark
National Institute on Drug Abuse (NIDA); University of Kentucky

Completed

Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

Pain | Hyperalgesia | Central Nervous System Sensitization

Denmark
Elorac, Inc.

Terminated

Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sézary Syndrome

United States
Indivior Inc.

Completed

Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disorder

Healthy Volunteer | Opioid-use Disorder

United States
Indivior Inc.

Completed

Induction of Opioid-Dependent Individuals Onto Buprenorphine and Buprenorphine/Naloxone

Opioid-related Disorders

United States
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
Universitaire Ziekenhuizen KU Leuven

Completed

The Effect of Naloxone and Methylnaltrexone on Esophageal Sensitivity in Health

Endogenous and Esophageal Sensitivity
Parc de Salut Mar
Food and Drug Administration (FDA)

Recruiting

Pharmacokinetics of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.

Healthy

Spain
Finnish Institute for Health and Welfare

Completed

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray (NALPILO)

Naloxone | Gambling | Spray | Opioid

Finland
Vanderbilt University Medical Center
National Institute on Drug Abuse (NIDA)

Completed

Reduced Opioid Analgesic Requirements Via Improved Endogenous Opioid Function

Chronic Pain

United States
Develco Pharma Schweiz AG

Unknown

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Opioid-Induced Constipation

United Kingdom, Bulgaria, Czechia, Germany, Poland, Portugal, Serbia, Slovakia, Spain
University of New Mexico

Not yet recruiting

Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose

Opioid Overdose | Opiate Overdose

United States
Kaiser Permanente
National Institute on Drug Abuse (NIDA); Denver Health and Hospital Authority

Completed

Impact of Direct Outreach to Expand Access to Naloxone in the Context of Standing Orders

Risk Behavior | Opioid Abuse | Overdose

United States
Emergent BioSolutions

Completed

Pharmacokinetics (PK) and Safety of Multiple Doses of Intranasal Naloxone in Healthy Adults

Opioid Overdose

United States
Duke University
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Buprenorphine Physician-Pharmacist Collaboration in the Management of Patients With Opioid Use Disorder: CTN 0075 (Pharm-OUD-Care)

Opioid Use Disorder

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Maintenance vs. Detoxification in Prescription Opioid Dependence

Opiate Dependence

United States
University of Washington
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Effects of a Kappa Agonist on Hot Flashes in Menopausal Women

Treatment of Menopausal Hot Flashes

United States
University of California, San Francisco
Johns Hopkins University

Terminated

The Effect of Chronic Pain on Delay Discounting in Methadone Patients

Opioid-use Disorder | Chronic Pain Syndrome

United States
Bicycle Health

Enrolling by invitation

Novel Induction to Buprenorphine/Naloxone

Opioid Use Disorder | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid Misuse

United States
National Institute on Drug Abuse (NIDA)
Johns Hopkins University

Terminated

Abuse Potential of Buprenorphine/Naloxone

Opioid-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Completed

Buprenorphine Combination Tablet Feasibility - 1

Opioid-Related Disorders

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine-Naloxone Sublingual Spray and Suboxone® Sublingual Film in Healthy Volunteers

Opiate Dependence

United States
Mundipharma Research GmbH & Co KG

Completed

OXN PR vs Placebo in Opioid-naive Subjects Suffering From Severe Pain Due to Bladder Pain Syndrome (BPS)

Pain | Interstitial Cystitis | Painful Bladder Syndrome

Poland, Germany, Hungary, Czechia, United Kingdom
University of California, Los Angeles
National Institute on Drug Abuse (NIDA); The Emmes Company, LLC

Completed

Cocaine Use Reduction With Buprenorphine (CURB)

Cocaine Dependence

United States

Search clinical trials for: naloxone placebo

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