Search clinical trials for: Nanoliposomal Irinotecan

Total 1432 results

Sanofi

Completed

Phase 1/1b Dose Escalation Study Evaluating BSI-201 as a Single Agent and in Combination With Irinotecan in Subjects With Advanced Solid Tumors

Tumors

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Irinotecan Followed by Radiation Therapy and Temozolomide in Treating Children With Newly Diagnosed Brain Tumor

Brain and Central Nervous System Tumors

United States
Georgetown University
National Cancer Institute (NCI)

Completed

Epirubicin Plus Irinotecan in Treating Patients With Advanced Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Yale University
National Cancer Institute (NCI)

Completed

Paclitaxel and Irinotecan in Treating Patients With Advanced Non-small Cell Lung Cancer

Lung Cancer

United States
Mayo Clinic
National Comprehensive Cancer Network

Completed

Trifluridine/Tipiracil and Irinotecan for the Treatment of Advanced Refractory Biliary Tract Cancer

Stage III Gallbladder Cancer AJCC v8 | Stage IIIA Gallbladder Cancer AJCC v8 | Stage IIIB Gallbladder Cancer AJCC v8 | Refractory Gallbladder Carcinoma | Stage IV Gallbladder Cancer AJCC v8 | Stage IV Distal Bile Duct Cancer AJCC v8 | Stage IV Intrahepatic Bile Duct Cancer AJCC v8 | Stage IVB Gallbladder... and other conditions

United States
National Cancer Institute (NCI)

Completed

Irinotecan Hydrochloride With or Without Alvocidib in Treating Patients With Advanced Stomach or Gastroesophageal Junction Cancer That Cannot Be Removed By Surgery

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma of the Stomach | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
Johns Hopkins All Children's Hospital
The V Foundation; Brain Tumor Alliance

Completed

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center

Completed

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer of the Esophagus or Stomach

Gastric Cancer | Esophageal Cancer

United States
Pfizer

Terminated

Clinical Study Of PI3K/mTOR Inhibitors In Combination With An Oral MEK Inhibitor Or Irinotecan In Patients With Advanced Cancer

Advanced Cancer

Italy, United States, Canada, Spain
University of Miami

Completed

Carboplatin, Irinotecan, and Radiation Therapy Followed By Docetaxel in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
Pfizer

Completed

Study Of Irinotecan Hydrochloride (Campto(R)) And Cisplatin Versus Etoposide And Cisplatin In Small Cell Lung Cancer

Small Cell Lung Carcinoma

France, Poland, Taiwan, Belgium, Italy, Netherlands, Spain, Egypt, Germany, Austria, Czech Republic, Switzerland, Russian Federation
Tianjin Medical University Cancer Institute and...
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

Efficacy and Safety of Anlotinib, Irinotecan and Temozolomide in the Treatment of Refractory or Recurrent Neuroblastoma in Children: an Open, Single Arm, Single Center, Phase II Clinical Study

Refractory or Recurrent Neuroblastoma in Children
Luye Pharma Group Ltd.

Enrolling by invitation

Safety, Tolerability, Pharmacokinetics (PK), and Primary Clinical Efficacy of LY01616 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

China
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Irinotecan Plus ICI D1694 in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Cisplatin, Irinotecan, and Radiation Therapy in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery

Esophageal Cancer

United States
Technical University of Munich

Unknown

Trabectedin and Irinotecan for Refractory Pediatric Sarcomas (TrIPReSarc)

Recurrent Ewing Sarcoma | Recurrent Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma
Seoul National University Hospital

Completed

Paclitaxel and Irinotecan in Advanced Gastric Cancer (TI-2ndAGC)

Advanced Gastric Cancer

Korea, Republic of
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
Zhejiang University

Not yet recruiting

Irinotecan Liposome for Resectable Pancreatic Cancer With or Without Addebelizumab (CAPT-02)

Resectable Pancreatic Cancer | Neoadjuvant Chemotherapy
Tianjin Medical University Cancer Institute and...
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer

Metastatic Biliary Tract Cancer

China
Sun Yat-sen University
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Doxorubicin Hydrochloride Liposome Combined With Irinotecan Versus VIT Regimen in the Treatment of Pediatric Rhabdomyosarcoma

Rhabdomyosarcoma, Child
National Cancer Institute (NCI)

Completed

Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy

Unspecified Childhood Solid Tumor, Protocol Specific

United States
University of Toyama

Unknown

Feasibility Study of CDDP + CPT-11 + PSK for Extensive-Stage Disease (ED) Small Cell Lung Cancer (RNCLC)

Small Cell Lung Cancer

Japan
Pfizer

Completed

Trial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.

Colorectal Neoplasms

Australia, Canada, United States, New Zealand
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Multicenter, Phase 3 Study of IBI343 Monotherapy Versus Treatment of Investigator's Choice in Subjects With Previously Treated, Claudin (CLDN) 18.2-positive, HER2-negative, Gastric or Gastroesophageal Junction Adenocarcinoma (G-HOPE-001)

Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

China
Symphogen A/S

Active, not recruiting

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Solid Tumor | Metastatic Cancer

United States, Canada, France, Spain
Hokkaido Gastrointestinal Cancer Study Group
Hokkaido University Hospital

Withdrawn

Phase I/II Study of Paclitaxel Plus CPT-11 in Pts. With 2nd Line Chemotherapy of Inoperable or Recurrent GC.

Gastric Cancer

Japan
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients

Metastatic Colorectal Cancer

China
National Cancer Institute (NCI)

Completed

Irinotecan, Oxaliplatin, and Capecitabine in Treating Patients With Unresectable Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
University of California, San Francisco
GlaxoSmithKline

Recruiting

Combination Therapy in Cancers With Mutations in DNA Repair Genes

Metastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene Mutation

United States
Sun Yat-sen University

Recruiting

Apatinib Mesylate Combined With IT Regimen for the Treatment of Recurrent or Refractory Pediatric Neuroblastoma

Neuroblastoma

China
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore

Completed

OXIRI [Oxaliplatin (O), Xeloda (X) and Irinotecan (I)] in Pancreatic Adenocarcinoma (OXIRI)

Pancreatic Cancer

Singapore
Cancer Institute and Hospital, Chinese Academy...
Chinese PLA General Hospital; China-Japan Friendship Hospital

Completed

Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

China
Eli Lilly and Company

Completed

A Study of the Combination of Pemetrexed and Irinotecan Every Two Weeks in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

France
Jazz Pharmaceuticals

Completed

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

Colorectal Neoplasms

United States, Canada
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment

Esophageal Squamous Cell Carcinoma

China
National Cancer Institute (NCI)

Completed

Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach

Adenocarcinoma of the Gastroesophageal Junction | Stage IV Gastric Cancer | Recurrent Gastric Cancer | Diffuse Adenocarcinoma of the Stomach | Intestinal Adenocarcinoma of the Stomach | Mixed Adenocarcinoma of the Stomach | Stage IIIB Gastric Cancer | Stage IIIC Gastric Cancer

United States
Hanmi Pharmaceutical Company Limited

Completed

Phase I of OratecanTM in Combination With Capecitabine in Patients With Advanced Solid Malignancies

Solid Tumor | Advanced Cancer

Korea, Republic of
Novartis

Terminated

Octreotide in the Prevention of Diarrhea in Patients Receiving Irinotecan for Metastatic Colon Cancer

Diarrhea | Colorectal Cancer

United States
Cancer Institute and Hospital, Chinese Academy...

Active, not recruiting

Irinotecan, TAS-102 Plus Bevacizumab as a Third-Line or Beyond Therapy in mCRC Patients

Metastatic Colorectal Cancer

China
First People's Hospital of Hangzhou

Recruiting

A Single-arm, Phase Ⅱ Clinical Trial of Anlotinib Hydrochloride Combined With Irinotecan or Docetaxel for Second Line Treatment of Nonsensitive Relapsed Small-cell Lung Cancer

Relapsed Small Cell Lung Cancer | Anlotinib

China
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Cetuximab, Cisplatin, and Irinotecan in Treating Patients With Metastatic Esophageal Cancer, Gastroesophageal Junction Cancer, or Gastric Cancer That Did Not Respond to Previous Irinotecan and Cisplatin

Gastric Cancer | Esophageal Cancer

United States
San Antonio Cancer Institute

Completed

Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Ludwig-Maximilians - University of Munich
Sanofi; Merck Sharp & Dohme LLC; Pfizer; Hoffmann-La Roche

Completed

Cap/Iri Plus Cetuximab Compared to Cap/ox Plus Cetuximab in Patients With Metastatic Colorectal Cancer.

Metastatic Colorectal Cancer
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Flavopiridol and Irinotecan in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan and Temozolomide in Treating Young Patients With Recurrent Neuroblastoma

Neuroblastoma

United States, Canada, Australia
University of California, San Francisco
National Cancer Institute (NCI)

Terminated

Gefitinib, Cisplatin, Irinotecan, and Radiation Therapy Before Surgery in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer That Can Be Removed By Surgery

Esophageal Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan and Flavopiridol in Treating Patients With Advanced Liver Cancer

Liver Cancer

United States

Search clinical trials for: Nanoliposomal Irinotecan

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