Search clinical trials for: nasal naloxone

Total 2735 results

Isfahan University of Medical Sciences

Completed

Randomized Trial of Intranasal Versus Intravenous Naloxone in Level of Consciousness in Suspected Opioid Overdose

Morphinan Opioid Overdose

Iran, Islamic Republic of
University of Texas Southwestern Medical Center

Completed

Impact of Low Dose Naloxone on Fentanyl Requirements in Pediatric ICU Patients

Opioid Tolerance

United States
Region Örebro County

Completed

Opioid Effects on Swallowing and Esophageal Sphincter Pressure

Opioid Induced Pharyngeal and Esophageal Dysfunction

Sweden
Carilion Clinic
Virginia Polytechnic Institute and State University

Not yet recruiting

Naloxone Education in Total Joint Patients

Surgery | Opioid Use | Pain, Musculoskeletal | Overdose of Opiate

United States
University of New Mexico
Kaleo Inc.

Completed

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Substance Use Disorder

Opioid-Related Disorders | Opiate Antagonist Overdose

United States
King's College London

Unknown

Buccal Versus Injectable Naloxone: a Phase I Healthy Volunteer Study

Opioid-Related Disorders | Drug Overdose
Aga Khan University Hospital, Pakistan

Unknown

Apneic Oxygenation in the Emergency Department (ApOxED)

Apneic Oxygenation
Indivior Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Depot Buprenorphine at Three Different Molecular Weights in Treatment-Seeking Subjects With Opioid Use Disorder

Opioid Use Disorder

United States
Henrik Endeman
Franciscus Gasthuis; Maasstad Hospital

Recruiting

Effect of HFNO Therapy on Respiratory Effort After Extubation (T-REX)

Respiratory Failure | Post Extubation Acute Respiratory Failure Requiring Reintubation

Netherlands
Emory University
National Institute on Drug Abuse (NIDA); Chestnut Health Systems

Withdrawn

Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use (A-CRA/MAT)

Behavior, Addictive | Opioid-Related Disorders
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

Starting Treatment With Agonist Replacement Therapies (START)

Opiate-related Disorders

United States
Haichao Li

Completed

Modified HFNC Oxygen in Patients Undergoing Bronchoscopy.

Bronchoscopy,Oxygen

China
Chang Gung University

Completed

High Flow Nasal Cannula During Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease

Taiwan
Ain Shams University

Not yet recruiting

High-flow Nasal Oxygenation Versus Standard Oxygenation for Gastrointestinal Endoscopy With Sedation in Obese Patients

Prevention of Intraoperative Hypoxia

Egypt
ADIR Association

Completed

During-exercise Physiological Effects of Nasal High-flow in Patients With Chronic Obstructive Pulmonary Disease (AIRVO-PHYSIO)

Chronic Obstructive Pulmonary Disease

France
Pfizer

Completed

Bioavailability Study of Naloxone 5 Milligrams (mg) Intramuscular (IM) Autoinjector

Healthy Volunteers

United States
Rigshospitalet, Denmark

Completed

Effect of High Dose Naloxone on Secondary Hyperalgesia

Pain | Naloxone | Hyperalgesia | Opioid Antagonist

Denmark
University of Utah
Intermountain Health Care, Inc.

Completed

Comparison of Humidified High Flow Nasal Cannula to Nasal CPAP in Neonates (HHFNC)

Respiratory Insufficiency

United States, China
Yih-Ing Hser
National Institute on Drug Abuse (NIDA); University of California, Los Angeles and other collaborators

Not yet recruiting

Extended-release Buprenorphine Compared to Sublingual Buprenorphine in Rural Settings (RXR) (RXR)

Substance-Related Disorders | Opioid-Related Disorders | Narcotic-Related Disorders

United States
Wake Forest University Health Sciences

Withdrawn

Long Acting Buprenorphine Injection Compared to Sublingual Buprenorphine/Naloxone Films

Opioid Use
Kaiser Permanente
National Institute on Drug Abuse (NIDA)

Active, not recruiting

The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy

Risk Behavior | Overdose

United States
Imperial College London
Chelsea and Westminster NHS Foundation Trust; Royal Brompton & Harefield NHS... and other collaborators

Recruiting

PROSAIC-19 - Prospective Longitudinal Assessment in a COVID-19 Infected Cohort (PROSAIC-19)

COVID-19 | SARS-CoV 2 | ARDS, Human | Immune System Disorder

United Kingdom
University of Texas Southwestern Medical Center

Completed

High-Flow Nasal Cannula and Desaturation Episodes in the Morbidly Obese Patients

Obesity | Sleep Apnea | Colonoscopy | High Flow Nasal Cannula | Desaturation of Blood

United States
Opiant Pharmaceuticals Inc

Completed

Pharmacodynamic Evaluation of Intranasal Nalmefene

Pharmacodynamic

United States
Mario Negri Institute for Pharmacological Research

Completed

GREAT - Good Response With Appropriate Treatment

Neoplasms | Cancer Pain

Italy
Lifespan
University of Rhode Island

Completed

Medication Maintenance Therapy in Community Pharmacy Settings (MATPharm)

Opioid-use Disorder

United States
RenJi Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine; Shanghai Oriental...

Recruiting

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity

Hypoxia | Gastric Cancer | Polyp of Colon | Colon Cancer | Esophagus Cancer

China
Assistance Publique - Hôpitaux de Paris

Completed

High Flow During Weaning From Mechanical Ventilation (FLOWEAN)

Acute Respiratory Failure

France
Viiral Nordic AB

Completed

A Post-Market Clinical Follow-up Investigation to Verify Performance and Safety of Viiral®Nasal Spray in Subjects With Dry Nose Symptoms

Rhinitis Sicca

Sweden
Hospital Clinic of Barcelona

Unknown

High Flow Nasal Cannula in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP) HF-study (HFS)

Patient Population Submitted to ERCP

Spain
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Unknown

Effects of Oropharyngeal Exercises on Patients With Primary Snore, Mild and Moderate Obstructive (EOE)

Primary Snore, Obstructive Sleep Apnea (Mild and Moderate).

Brazil
Maastricht University Medical Center

Recruiting

HFNC vs LFNC in Patients With AF Undergoing RFCA Under Deep Sedation.

Radiofrequency Ablation | Deep Sedation | Oxygen Therapy

Netherlands
Yonsei University

Completed

Efficacy of High Flow Nasal Oxygen During Sleep Endoscopy in Patients of Obstructive Sleep Apnea

Obstructive Sleep Apnea

Korea, Republic of
Brooke Army Medical Center

Completed

Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation

Hypoxia

United States
Klaus Kenn
Schön Klinik Berchtesgadener Land

Completed

Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis (IPF/Oxymizer2)

Idiopathic Pulmonary Fibrosis | Hypoxemia

Germany
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo; Conselho Nacional de...

Completed

Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction

Obstructive Sleep Apnea of Newborn

Brazil
Rigshospitalet, Denmark
National Institute on Drug Abuse (NIDA); University of Kentucky

Completed

Effect of High-dose Naloxone Infusion on Pain and Hyperalgesia in Patients Following Groin-Hernia Repair.

Pain | Hyperalgesia | Central Nervous System Sensitization

Denmark
Elorac, Inc.

Terminated

Naloxone Hydrochloride Study for Relief of Pruritus in Patients With MF or SS Forms of CTCL

Lymphoma, T-Cell, Cutaneous | Mycosis Fungoides | Sézary Syndrome

United States
Mahidol University

Completed

Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section

Morphine Adverse Reaction

Thailand
Unidad de Investigacion Medica en Epidemiologia...
Fondo para el Fomento a la Investigacion Medica; Doctorado en Farmacologia...

Completed

Study of Vanadium Supplement in Patients With Impaired Glucose Tolerance

Prediabetic State

Mexico
Larissa University Hospital
Sotiria General Hospital

Recruiting

DUET Versus Standard Interface for Hypercapnic COPD Patients

COPD | COPD Exacerbation | Hypercapnia

Greece
University of Chicago
Community Outreach Intervention Projects; Cook County Sheriff Office; Cook County... and other collaborators

Recruiting

Reducing Opioid Mortality in Illinois (ROMI)

Opioid Use | Opioid-use Disorder

United States
Develco Pharma Schweiz AG

Unknown

Naloxone HCl PR Tablets in Patients With Opioid Induced Constipation (Naxos)

Opioid-Induced Constipation

United Kingdom, Bulgaria, Czechia, Germany, Poland, Portugal, Serbia, Slovakia, Spain
Indiana University

Withdrawn

Comparison of High-flow Oxygen With or Without Nasal Positive Airway Pressure (PAP) During Propofol Sedation for Colonoscopy in an Ambulatory Surgical Center

Colonoscopy | Positive-Pressure Respiration

United States
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)

Dry Eye Disease

United States
Seema Capoor

Completed

Topical Naloxone to Diagnose Ocular Pain

Dry Eye Syndromes | Neuropathic Pain

United States
Ullevaal University Hospital
Mundipharma AB

Completed

A Comparison of Oxycodone/Naloxone and Oxycodone After Laparoscopic Hysterectomy

Postoperative Pain | Opioid Induced Constipation

Norway
BioDelivery Sciences International

Withdrawn

Evaluation of BEMA® Buprenorphine NX for Buprenorphine Induction of Opioid Dependent Subjects

Opioid Dependence

United States
US Department of Veterans Affairs
National Institute on Drug Abuse (NIDA); Reckitt and Colman

Completed

Determine the Safety of a Sublingual Tablet Formulation of Buprenorphine and Naloxone by Extending the Combination Tablet Availability to Physicians in Office-Based Practice

Opiate Dependence

United States
Hospital do Coracao
Ministry of Health, Brazil; Berry Consultants

Completed

High-Flow Nasal Oxygen Cannula Compared to Non-Invasive Ventilation in Adult Patients With AcuTE Respiratory Failure (RENOVATE)

Respiratory Failure | Respiratory Insufficiency

Brazil

Search clinical trials for: nasal naloxone

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