Search clinical trials for: new local drug delivery

Total 8975 results

Instituto Mexicano del Seguro Social

Completed

Quality of Life and Pain With Infiltration or Suprascapular Nerve Block in Glenohumeral Arthirtis

Shoulder Arthritis

Mexico
McGill University Health Centre/Research Institute...
University of Chile

Unknown

Single Versus Double Injection Costoclavicular Block

Upper Extremity Injury

Canada
Fayoum University Hospital

Completed

Dexamethasone Versus Dexmedetomidine

Postoperative Pain

Egypt
University of Missouri-Columbia

Terminated

Botulism Toxin Injection as a Treatment for Arthritis of the Basal Thumb Joint

Arthritis Multiple Joint

United States
Isfahan University of Medical Sciences

Completed

Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair

Hypospadias
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Dental Anesthesia in Pregnant Women With Rheumatic Heart Disease

Pregnancy | Dental Caries | Rheumatic Heart Disease

Brazil
Sohag University

Not yet recruiting

Prospective Comparative Study Between Ultrasound-guided Continuous Erector Spinae Plane Block and the Use of Intravenous Patient Controlled Analgesia for Management of Pain in Patients With Multiple Fracture Ribs

Multiple Fracture Ribs
Tanta University

Recruiting

Comparison Between Ultrasound Guided Ozone, Platelet-Rich Plasma or Steroid Injection in the Treatment of Sacroiliitis; a Randomized Double Blinded Controlled Study

the Efficacy of Ultrasound Guided Sacroiliac Injection of Ozone, Platelet Rich Plasma (PRP) or Steroid for Treatment of Sacroiliitis

Egypt
Carl Ola Landgren, MD, PhD
Bristol-Myers Squibb

Recruiting

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma (Iber-KDd)

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Sanofi

Completed

Evaluation of SAR408701 in Japanese Patients With Advanced Malignant Solid Tumors

Neoplasm Malignant

Japan
Emory University

Terminated

Corticosteroid(CS) + Lido or Corticosteroid(CS) Alone

Tenosynovitis

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

Malignant Neoplasms of Male Genital Organs

United States
Brian Williams
University of Pittsburgh

Completed

4-drug Nerve Block Versus Plain Local Anesthetic for Knee and Hip Arthroplasty Analgesia in Veterans

Pain

United States
Shire

Completed

FST-201 in the Treatment of Acute Otitis Externa

Acute Otitis Externa

American Samoa
University of Washington

Completed

Early Ultrasound-guided Nerve Block for Painful Hand Injuries in the Emergency Department

Hand Injuries | Hand Injuries and Disorders

United States
Wake Forest University Health Sciences

Completed

Perineural Steroids for Peripheral Nerve Blocks

Osteoarthritis, Knee

United States
Faculty of Medicine, Sousse

Completed

Magnesium-sulfate as Adjuvant in Prehospital Femoral Nerve Block for Patient With Diaphysial Femoral Fracture.

Acute Pain Due to Trauma
Janssen Research & Development, LLC

Completed

An Efficacy and Safety Study of Daratumumab in Patients With Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy (Including a Proteasome Inhibitor [PI] and Immunomodulatory Drug [IMiD]) or Are Double Refractory to a PI and an IMiD

Multiple Myeloma

United States, Spain, Canada
Rush University Medical Center

Withdrawn

Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial

Symptomatic Osteoarthritis of the Knee
Joseph Hazelton

Completed

A Double-Blind, Randomized, Active- and Placebo-Controlled, Multiple-Dose Multi-Center Phase 3 Study of the Safety and Efficacy of CL-108 in the Treatment of Moderate to Severe Acute Pain and Opioid-Induced Nausea and Vomiting (OINV)

Pain | Nausea | Vomiting

United States
Grupo de Estudos Multicentricos em Onco-Hematologia
Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Unknown

Randomized Clinical Trial With Aminocaproic Acid in the Prevention of Exodontic Bleeding in Anticoagulants Patients

Oral Hemorrhage

Brazil
M.D. Anderson Cancer Center

Completed

Papillary Serous Carcinoma of the Endometrium

Endometrial Cancer

United States
Asker & Baerum Hospital

Completed

Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty

Osteoarthritis of the Knee

Norway
Xiuli Zuo

Not yet recruiting

Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Shandong University

Unknown

A Pilot Study of a 14-day Modified Sequential Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
Göteborg University

Recruiting

Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery (OS-PCC)

Obesity | Pain, Postoperative

Sweden
Stanford University

Completed

Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA

Breast - Female

United States
Merck Sharp & Dohme LLC

Withdrawn

A Study of Single Dose Pain Therapy in Patients With Painful Diabetic Neuropathy (0000-115)

Painful Diabetic Neuropathy
University of Sao Paulo

Completed

Four Interventions in the Management of Psychomotor Agitation, Safety and Efficacy Evaluation

Psychomotor Agitation

Brazil
Sanofi

Recruiting

A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme (SHORTEN)

Fabry's Disease

United States
Hospices Civils de Lyon

Recruiting

Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma (Mel-ImmAdj)

Melanoma

France
Nemours Children's Clinic

Completed

Awake Caudal Catheter vs General Anesthesia

Inguinal Hernia

United States
Mansoura University

Active, not recruiting

Comparison of Zero- and Two-centimeter Distance From Sapheno-femoral Junction in Laser Ablation of Varicose Vein

Varicose Veins | Venous Insufficiency | Venous Leg Ulcer | Venous Reflux

Egypt
Pain Medicine Department

Completed

Efficacy of GONB in Patients of Migraine

Headache | Chronic Migraine

Pakistan
Tanta University

Completed

Pediatric Postoperative Analgesia With Quadratus Lumborum Block(QLB) And Dexamethasone As An Adjuvant To Bupivacaine. (QLB)

Abdominal Surgery | Post Operative Pain | Quadratus Lumborum Block | Pediatric

Egypt
Rush University Medical Center

Withdrawn

Multimodal Analgesia in Shoulder Arthroplasty

Shoulder Pain | Opioid Use

United States
Medical College of Wisconsin

Completed

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Headache | Neurofibromatoses | Abdominal Neoplasm | Tumor | Seizure Disorder | Hydrocephalus | Spine Deformity

United States
Mayo Clinic

Completed

The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.

Blood Pressure | Epistaxis

United States
OhioHealth

Completed

Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)

Osteoarthritis, Knee | Osteoarthritis, Hip | Osteoarthritis, Shoulder

United States
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block

Pharmacokinetics | Pharmacodynamics | Drug-induced QT Prolongation
University of Aarhus
Aarhus University Hospital; AP Moeller Foundation; Bendtsen, Thomas Fichtner,...

Completed

Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block

Pain, Postoperative | Anesthesia, Local | Hip Fractures
University of Florida

Completed

Histamine Glutamate Antagonism in Stroke

Cerebral Edema | Acute Cerebrovascular Accident

United States
Scott and White Hospital & Clinic

Completed

Effectiveness Study of Different Local Anesthetic Mixtures (CA)

Pain

United States
Zagazig University

Completed

Suprascapular Nerve Block With Oral Gabapentin For Pain Management In Frozen Shoulder

Pain, Shoulder

Egypt
Seattle Children's Hospital
Seattle Children's Research Institute Center for Clinical and Translational...

Terminated

Post Operative Pain Control After Pediatric Hip Surgery

Hip Surgery | Post Operative Pain Control
Henlix, Inc

Completed

An Open-label, Phase 1 Study to Determine the Maximum Tolerated Dose of HLX07,in Patients With Advanced Solid Cancers

Solid Tumour

Taiwan, United States
Tang-Du Hospital

Unknown

Effect of Pre-injection of Lidocaine on Myoclonus Induced by Induction With Etomidate in Elderly Patients During General Anesthesia

General Anesthesia

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell Transplantation

Primary Myelofibrosis | Acute Leukemia | Myelodysplastic Syndrome | Secondary Myelofibrosis | Hematologic and Lymphocytic Disorder

United States
Indonesia University
Singapore General Hospital

Not yet recruiting

Medical Thoracoscopy for Undiagnosed Transudative and Exudative Pleural Effusions

Pleural Effusion

Indonesia
University of Alabama at Birmingham

Completed

Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty

Pain, Postoperative | Urethral Stricture

United States

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