Search clinical trials for: Placebo metformin

Total 55130 results

Columbia University

Recruiting

Metformin in Heart Failure Without Diabetes (Met-HeFT)

Heart Failure

United States
Canadian Cancer Trials Group
National Cancer Institute (NCI); ETOP IBCSG Partners Foundation; ICR-CTSU

Completed

A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer

Breast Cancer

United States, Canada, Switzerland, United Kingdom
Hoffmann-La Roche

Completed

A Study of RO5095932 in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

United States
Hoffmann-La Roche

Completed

A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy

Diabetes Mellitus Type 2

Korea, Republic of, China
Assistance Publique Hopitaux De Marseille

Completed

Effect of GLP-1 Receptor (GLP-1R) Agonists on Cardiac Function and on Epicardial Adipose Tissue (EAT) Volume and on Myocardial TG Content in Obese Diabetics

Obesity | Diabetes

France
Steno Diabetes Center Copenhagen

Completed

Effect of Metformin Versus Repaglinide Treatment in Non-Obese Type 2 Diabetic Patients Uncontrolled by Diet

Diabetes Mellitus, Type 2

Denmark
University Magna Graecia

Completed

Metformin and Folate Supplementation in Polycystic Ovary Syndrome (PCOS) Patients

Polycystic Ovary Syndrome | Anovulation

Italy
Medical University of Bialystok
Medical Research Agency, Poland

Not yet recruiting

Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility (METIN)

Infertility, Female
National University of Ireland, Galway, Ireland
Health Research Board, Ireland; University Hospital of Limerick; University College... and other collaborators

Completed

A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

Gestational Diabetes

Ireland
University Medical Centre Ljubljana

Unknown

The Effects of Empagliflozin on Arterial Wall Characteristics

Diabetes Complications | Diabetes Mellitus, Type 1 | Vascular Stiffness | Hypoglycemic Agents

Slovenia
University of Texas Southwestern Medical Center

Completed

Preservation of Beta-cell Function in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

United States
Merck Sharp & Dohme LLC

Completed

A Dose-Range Finding Study in Participants With Type 2 Diabetes (MK-3102-006)

Type 2 Diabetes Mellitus
Anuja Dokras
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Comparing the Effects of Oral Contraceptive Pills Versus Metformin (COMET-PCOS)

PCOS

United States
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety and Efficacy of MK-3577 in Participants With Type 2 Diabetes Mellitus (MK-3577-009)

Type 2 Diabetes Mellitus
Kyongtae Ty Bae, M.D., Ph.D.
University of Maryland, Baltimore; United States Department of Defense; University... and other collaborators

Completed

Metformin as a Novel Therapy for Autosomal Dominant Polycystic Kidney Disease (TAME)

Polycystic Kidney, Autosomal Dominant

United States
Wake Forest University Health Sciences
University of South Florida; National Institute on Aging (NIA)

Recruiting

Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction (Met-PEF)

Heart Failure With Preserved Ejection Fraction

United States
Sunovion

Completed

A Clinical Trial Study to Determine the Effect of an Investigational Drug (SEP-363856) Has on the Way That the Drug Metformin Travels Through the Body in People With Schizophrenia.

Schizophrenia

United States
Kristian Karstoft
University of Copenhagen

Completed

The Interaction Between Metformin and Acute Exercise

Diabetes Mellitus, Type 2 | Impaired Glucose Tolerance

Denmark
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Recruiting

Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma

Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma

United States
Cynthia Calkin
Stanley Medical Research Institute

Completed

Treating Insulin Resistance as a Strategy to Improve Outcome in Refractory Bipolar Disorder (TRIO-BD)

Bipolar Disorder

United States, Canada
Lars Christian Gormsen

Completed

Effects of Metformin on Hepatic FFA Metabolism

Type 2 Diabetes | Dyslipidemia
National Cancer Institute (NCI)

Completed

Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus

Esophageal Cancer | Barrett Esophagus

United States, Puerto Rico, Canada
Government Dental College and Research Institute...

Unknown

Locally Delivered 1% Metformin Gel in the Treatment of Intrabony Defects in Chronic Periodontitis

Intrabony Defects in Chronic Periodontitis

India
Odense University Hospital

Completed

The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

Denmark
Duke University

Terminated

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) (NAFLD)

Fatty Liver

United States
OPKO Health, Inc.

Completed

A Trial of TT223 in Patients With Type 2 Diabetes Who Are Taking Metformin and/or Thiazolidinedione

Diabetes Mellitus, Type 2

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Metformin in Pregnant PCOS Women (PregMet)

Polycystic Ovary Syndrome

Norway
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Uterine Artery Blood Flow in Pregnant Women With PCOS Treated With Metformin (FlowMet)

Polycystic Ovary Syndrome

Norway
Seoul National University Hospital
Daewoong Pharmaceutical Co. LTD.

Terminated

The Effect of Metformin on Obesity and Metabolic Disturbance in Patients Taking Clozapine

Schizophrenia

Korea, Republic of
Hospital Civil de Guadalajara

Unknown

Metformin and Systemic Inflammation in HIV (Metfo)

PreDiabetes | HIV-1-infection

Mexico
University of Dundee

Completed

MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease (MET-REMODEL)

Coronary Artery Disease | Insulin Resistance | PreDiabetes | Left Ventricular Hypertrophy

United Kingdom
Sanofi

Completed

Multiple Ascending Dose Study in Healthy Male Subjects and Overweight to Obese Male and Female Type 2 Diabetes Mellitus (T2DM) Patients

Type 2 Diabetes Mellitus

Germany
Virginia Commonwealth University

Terminated

Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome | PCOS | Insulin Sensitivity

United States
University of Exeter
University of Bristol; University of Dundee

Withdrawn

Autoimmune Diabetes Accelerator Prevention Trial (adAPT)

Prediabetic State

United Kingdom
Pennington Biomedical Research Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Metabolic Effects of Metformin Therapy in Obstructive Sleep Apnea (MET-OSA)

Sleep Apnea, Obstructive

United States
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation

Completed

Metformin Therapy for Overweight Adolescents With Type 1 Diabetes

Type 1 Diabetes

United States
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Completed

Effect of Metformin and Probiotics on Gut Microbiome in Healthy Subjects

Healthy

China
Kristian Karstoft
University of Copenhagen

Completed

The Interaction Between Metformin and Physical Training

Diabetes Mellitus, Type 2 | Impaired Glucose Tolerance

Denmark
Merck Sharp & Dohme LLC

Terminated

Study MK0767 and Metformin in Type 2 Diabetic Patients (0767-020)

Diabetes Mellitus, Type 2
Jack Yanovski, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Metformin to Treat Obesity in Children With Insulin Resistance

Obesity | Hyperinsulinemia

United States
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Semnan University of Medical Sciences

Terminated

Metformine and CC Compared With Placebo and CC for Induction Ovulation in PCOS Patients With Insulin Resistant

Polycystic Ovary Syndrome | Hyperandrogenism
Huazhong University of Science and Technology
Hubei Xinhua Hospital; Wuhan Iron and Steel Workers' Hospital; Wuhan Pu-Ai Hospital

Completed

Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Diabetic Patients

Diabetes Mellitus, Type 2

China
University of Chicago

Suspended

Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Brenner Tumor | Malignant Ascites | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Stage IV Primary Peritoneal Cavity Cancer and other conditions

United States
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of Teneligliptin in Combination With Metformin in Chinese Patients With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
Austrian Breast & Colorectal Cancer Study Group
Merck Gesellschaft mbH, Austria

Terminated

A Randomized, Placebo-controlled, Double-blind Phase II Study Evaluating if Glucophage Can Avoid Liver Injury Due to Chemotherapy Associated Steatosis (G-LUCAS)

Colorectal Cancer | Steatohepatitis

Austria
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Completed

A Study of DBPR108 and Metformin Hydrochloride Combination Therapy in Patients With T2DM

Type 2 Diabetes Mellitus

China
Universiteit Antwerpen
University Hospital, Antwerp

Active, not recruiting

Metformin as RenoProtector of Progressive Kidney Disease (RenoMet)

Chronic Kidney Diseases

Belgium
Damanhour University

Completed

Metformin Effect on Fracture Healing in Post-Menopausal Women

Bone Fracture

Egypt
Norwegian University of Science and Technology

Terminated

Metformin in Assisted Reproduction-MET-AR-study

Polycystic Ovary Syndrome

Norway

Search clinical trials for: Placebo metformin

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