Search clinical trials for: placebo oxycodone / naloxone

Total 54578 results

Pfizer

Terminated

A 2 Week Blinded Study For Pain Due To Arthritis Of The Knee

Osteoarthritis

United States
University of Southern California

Completed

Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Hand Surgery

Ganglion Cysts | Carpal Tunnel Syndrome | Dupuytren Contracture | Trigger Digit | De Quervain Disease

United States
Alkermes, Inc.

Completed

A Study of the Abuse Liability Potential of Samidorphan in Healthy, Non-Dependent, Recreational Opioid Users

Healthy Volunteers

United States
Turku University Hospital
University of Turku; University of Helsinki

Completed

Clinical Trial on Individual Characteristics Affecting Pain Drug Therapy in Neonates (NeoPopGen)

Critical Illness

Finland
Tetra Bio-Pharma
Cognitive Research Corporation

Recruiting

Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain (REBORN)

Cancer | Breakthrough Cancer Pain

United States
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Terminated

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety

Arthroplasty

United States, United Kingdom, Belgium, Spain, Canada, Finland, New Zealand, Sweden
Janssen-Cilag A.G., Switzerland

Completed

Comparison of Two Dosage Strengths of Transdermal Fentanyl Versus Transdermal Buprenorphine and Placebo in Acute Pain Models in Healthy Volunteers.

Pain
Mallinckrodt

Completed

Fasting Study of Controlled-Release Oxycodone Hydrochloride 40 mg Tablets and OxyContin® 40 mg Tablets

Healthy

United States
Katja venborg Pedersen
Aalborg University Hospital

Completed

Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing PCNL

Kidney Stones

Denmark
Artoss Inc.

Completed

Artoss Foot and Ankle Surgery Registry (ARK)

Trauma Injury | Deformity; Bone | Arthritis Foot

United States
Artoss Inc.

Active, not recruiting

Artoss Prospective Spine Registry Outcomes (ASTRO)

Spinal Fusion

United States
University of Campania "Luigi Vanvitelli"

Completed

DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 Diabetes

Chronic Foot Ulcers

Italy
Mayo Clinic
National Center for Research Resources (NCRR)

Completed

Comparison of the Effects of Tapentadol and Oxycodone on Gastrointestinal and Colonic Transit in Humans (tap-oxy)

Effects of 2 Mu-opiates on Gastrointestinal Transit

United States
University Health Network, Toronto
Canadian Society of Hospital Pharmacists

Withdrawn

Dosing Intervals of Opioid Medication for Chronic Pain

Chronic Pain

Canada
Pain Therapeutics

Completed

Abuse Potential Study of PF-00345439

Opioid Users

United States
Pfizer

Terminated

Safety and Pharmacokinetic Study of ALO-02 in Children Ages 7-17 With Pain

Moderate-severe Pain

United States
Pain Therapeutics

Completed

Study to Evaluate the Subjective Effects of PTI-801 in Non-Physically Dependent Subjects With a History of Drug Abuse

Opioid-Related Disorders

United States
Purdue Pharma LP

Completed

The Safety and Efficacy of the Buprenorphine Transdermal System (BTDS) in Subjects With Chronic Back Pain. (BP96-0604)

Back Pain

United States
Kasr El Aini Hospital
Mansoura University

Completed

Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients

Elderly | Anesthesia, Spinal

Egypt
University of Parma

Terminated

Controlled-Release Oxycodone For Postoperative Analgesia After Video-Assisted Thoracic Surgery

Pain, Postoperative | Anesthesia Recovery Period

Italy
Stephanie B. Seminara, MD

Enrolling by invitation

Opioid Antagonism in Hypogonadotropic Hypogonadism

Hypogonadotropic Hypogonadism

United States
Dartmouth-Hitchcock Medical Center

Completed

Role of Endorphins in Perception of Dyspnea With Resistive Loading in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States
Pfizer

Completed

Healthy Volunteers Study to Estimate the Effects of Food on the Bioavailability of Oxycodone and Naltrexone/6- Β -Naltrexol From a Extended Release Formulation of Oxycodone With Sequestered Naltrexone

Healthy

United States
Roswell Park Cancer Institute

Completed

Gabapentin, Methadone Hydrochloride, and Oxycodone Hydrochloride in Improving Quality of Life in Patients With Stage II-IV Head and Neck Cancer During Chemoradiation

Pain | Stomatitis | Head and Neck Squamous Cell Carcinoma

United States
Rush University Medical Center
Vanderbilt University Medical Center

Recruiting

Efficacy of Spinal Manipulation Therapy or Mindfulness-based Reduction Therapy on Patients With Chronic Low Back Pain

Chronic Low-back Pain

United States
Cairo University

Unknown

Evaluation of Marginal Bone Loss After Immediate Implant Placement in Maxillary Esthetic Zone With Nanobone Versus Xenograft

Implant Placement in Maxillary Esthetic Zone

Egypt
Acura Pharmaceuticals Inc.

Completed

Study of the Abuse Liability of Oxycodone HCl/Niacin in Subjects With a History of Opioid Abuse

Opioid Abuse

United States
Lotus Clinical Research, LLC
Mallinckrodt

Completed

An Open Label, Prospective Study of the Analgesic Efficacy of Oral Xartemis Compared to Generic Oxycodone/APAP( Acetaminophen) in the Treatment of Moderate to Severe Post Operative Pain.

Post Operative Pain

United States
University of California, San Diego

Completed

The Role of Opioidergic Systems in Breathing Based Analgesia

Pain

United States
Indivior Inc.

Completed

Treatment Seeking Participants With Opioid Use Disorders Assessing Tolerability of Depot Injections of Buprenorphine

Opioid Dependence | Opioid Related Disorders

United States
General Hospital of Ningxia Medical University

Not yet recruiting

The Effect of Oxycodone Hydrochloride on CRBD After TURBT Under General Anesthesia

Effect of Drug | Adverse Effect of Opioids

China
Nanjing First Hospital, Nanjing Medical University

Not yet recruiting

Compare Continuous Gastrocnemius Plane Block With Intravenous Analgesia After Foot and Ankle Surgery

Foot Ankle Injuries
Cephalon

Completed

Fentanyl Buccal Tablets Versus Immediate Release Oxycodone for Breakthrough Pain in Patients With Chronic Pain

Chronic Pain

United States
Kuopio University Hospital

Withdrawn

Naloxone Methadone Combination (NAMEKO) (NAMEKO)

Opiate Dependence

Finland
National Institute on Alcohol Abuse and Alcoholism...

Completed

Medication and Counseling for Controlled Drinking (Project SMART)

Alcohol Drinking | Alcoholism | Alcohol Abuse | Alcohol-related Disorders

United States
Dr. Frank Behrens
University Hospital Frankfurt, Department of Anaesthesiology; IRON4U; University...

Recruiting

Postoperative i.v. Iron Substitution in Patients With Diagnosed Iron Deficiency (IDA-II)

Iron Deficiency Anemia

Germany
Alkermes, Inc.

Completed

ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids

Opiate Dependence
New York State Psychiatric Institute

Completed

Effects of Cannabis on Prescription Drug Abuse Liability and Analgesia

Pain | Abuse, Drug

United States
University of Maryland, Baltimore

Terminated

Relieving Acute Pain (RAP) Study: A Pilot Study

Trauma | Opioid Use | Spine Fusion

United States
Medical University of Lublin
University of Rzeszow

Completed

Postoperative Analgesia After Minithoracotomy

Postoperative Pain | Mitral Valve Disease

Poland
Ensysce Biosciences
PRA Health Sciences

Completed

Study of PF614 Compared to OxyContin® in Healthy Volunteers (SAD)

Healthy

United States
Cephalon

Completed

Efficacy and Safety of Fentanyl Buccal Tablets Compared With Oxycodone for the Management of Break Through Pain

Chronic Pain

United States
Zuyderland Medisch Centrum
AtriCure, Inc.

Recruiting

Intercostal Nerve Cryoablation Versus Epidural Analgesia for Nuss Repair of Pectus Excavatum (ICE)

Funnel Chest | Pectus Excavatum

Netherlands
NYU Langone Health

Completed

An Analysis of the Efficacy of a Pre-Emptive Multimodal Pain Regimen in Reducing Acute Post-Operative Pain and Narcotic Pain Medication Requirements in Spine Surgery

Pain, Postoperative | Spine Injuries and Disorders | Narcotic Use

United States
INSYS Therapeutics Inc

Completed

Study of Buprenorphine Sublingual Spray Versus Standard of Care Narcotic Therapy for the Treatment of Post-Operative Pain

Pain, Postoperative

United States
Pfizer

Completed

Safety Study of Oxycodone Hydrochloride and Naltrexone Hydrochloride Extended-Release Capsules in Subjects With Moderate to Severe Chronic Noncancer Pain

Chronic Noncancer Pain

United States
National Center for Complementary and Integrative...

Completed

Herb-Opioid Interactions

Pain

United States
Lawson Health Research Institute

Completed

Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery

Spinal Anesthesia | Knee Arthroplasty | Hip Arthroplasty

Canada
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Center for AIDS...

Completed

Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP (PARTNERUP)

Hepatitis C | Hiv | Opioid Use Disorder | Opioid Use | Risk Reduction

United States
University of California, San Francisco
National Center for Advancing Translational Sciences (NCATS)

Completed

EMR Defaults to Nudge Opioid Prescribing

Pain, Acute | Opioid Use, Unspecified

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