Search clinical trials for: Protease Inhibitors

Total 64281 results

Anhui Provincial Children's Hospital

Unknown

The Efficacy and the Safety of Dexmedetomidine Sedation on the Pediatric Intensive Unit(PICU) Patients.

Failed Conscious Sedation During Procedure
Bezmialem Vakif University

Completed

Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy

Chronic Cholecystitis

Turkey
Ruijin Hospital
Chugai Pharma China

Completed

Different Anti-Spastic Therapy Strategies After CABG Using Radial Artery Grafts (ASRAB-Pilot)

Coronary Artery Bypass Graft | Radial Artery Grafts | Antispastic Therapy | Pilot Study

China
Zagazig University

Completed

Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries

Agitation, Emergence

Egypt
Yonsei University

Completed

Sedation Regimen in Patients Undergoing Cardiac Electrophysiology Study and Ablation : a Comparison Between Dexmedetomidine-remifentanil and Midazolam-remifentanil Combinations

Cardiac Arrhythmia
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia | Childhood B Acute Lymphoblastic Leukemia

United States, Canada, Australia, New Zealand, Switzerland
National Cancer Institute (NCI)
Canadian Cancer Trials Group

Active, not recruiting

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative

United States, Canada, Israel, Puerto Rico
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Calaspargase Pegol or Pegaspargase and Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia | Childhood B Acute Lymphoblastic Leukemia

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma

United States
Peking University First Hospital

Completed

Low-dose S-ketamine and Dexmedetomidine in Combination With Opioids for Postoperative Analgesia

Dexmedetomidine | Postoperative Analgesia | S-ketamine | Sufentanil | Scoliosis Correction

China
Anqing Municipal Hospital

Completed

Effect of Co-administration Lidocaine and Dexmedetomidine on Quality of Recovery

Dexmedetomidine | Lidocaine | Quality of Recovery(QoR-40), Preoperative and Postoperative

China
Assiut University

Completed

Analgesic Efficacy of Two Doses of Dexmedetomidine as Adjuncts to Lidocaine for Intravenous Regional Anesthesia

Limb Deformity

Egypt
Arlyne Thung

Completed

A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients

Adenoid Hypertrophy

United States
Aswan University Hospital

Completed

Ultrasound Guided Infraclavicular Brachial Plexus Block Using Levo-bupivacaine Alone or Combined With Dexmedetomidine for Hand and Forearm Surgeries

Forearm | Hand | Wrist | Acquired Deformity of Elbow

Egypt
Second Affiliated Hospital of Wenzhou Medical University

Unknown

Combination With Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Patients

Anxiety

China
Brasilia University Hospital

Completed

Premedication With Intranasal Dexmedetomidine or Midazolam for Prevention of Emergence Agitation in Children

Emergence Delirium

Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Enasidenib in Combination With Cobimetinib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia

United States
University Hospital Inselspital, Berne

Completed

Adjunctive Sedation With Dexmedetomidine for the Prevention of Severe Inflammation and Septic Encephalopathy (ADVISE)

Sepsis-Associated Encephalopathy

Switzerland
University Hospitals Cleveland Medical Center
Hospira, now a wholly owned subsidiary of Pfizer

Terminated

Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions

Stroke | Brain Ischemia | Vasospasm, Intracranial | Hemorrhage, Intracranial

United States
Theodor Bilharz Research Institute

Completed

Goal Directed Propofol Sedation With Magnesium Sulphate Versus Dexmedetomidine for ERCP Procedure

Lack of Drug Action

Egypt
Weill Medical College of Cornell University

Terminated

Effects of Electronic Cigarettes on Lung Biology

Lung Disease | Lung Disorder

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ganetespib in Combination With Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-III Esophageal Cancer

Gastroesophageal Junction Adenocarcinoma | Stage IIA Esophageal Cancer AJCC v7 | Stage IIB Esophageal Cancer AJCC v7 | Stage IIIA Esophageal Cancer AJCC v7 | Stage IIIB Esophageal Cancer AJCC v7 | Stage IIIC Esophageal Cancer AJCC v7 | Malignant Neoplasm of the Cervical Esophagus | Malignant Neoplasm...

United States
Assiut University

Unknown

Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery

Cesarean Section

Egypt
Sira Bang

Completed

Anticholinergic Premedication for Sedation With Dexmedetomidine During Spinal Anesthesia

Bradycardia

Korea, Republic of
TC Erciyes University

Completed

Controlled Hypotension During Functional Endoscopic Sinus Surgery

Hemorrhage
Ain Shams University

Recruiting

Comparative Study Between Two Adjuvant Drugs to Bupivacaine for Post-operative Epidural Analgesia in Abdominal Surgeries

Epidural Analgesia

Egypt
The Cooper Health System

Completed

Time to Post-Anesthesia Neurological Evaluation With Three Different Anesthetic Techniques

Carotid Artery Stenosis

United States
Athens General Children's Hospital "Pan. & Aglaia...

Completed

Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children

Effect of Anesthesia in Postoperative Pain | Effect of Anesthesia in Extubation Time | Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit | Effect of Anesthesia in Postoperative Adverse Events | Effect of Anesthesia in Discharge Time From the Hospital

Greece
University of Chicago
Hospira, now a wholly owned subsidiary of Pfizer

Terminated

Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)

Critical Illness | Mechanical Ventilation

United States
Yao Yusheng
West China Hospital

Completed

Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children

Delirium on Emergence | Inhalational Anesthetics Adverse Reaction | Strabismus Following Ocular Surgery

China
National Cancer Institute (NCI)

Completed

Dasatinib and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1

United States, Canada, Australia, New Zealand, Puerto Rico
Northwestern University
National Cancer Institute (NCI)

Not yet recruiting

Pembrolizumab and Tazemetostat to Overcome Immune Tolerance Following ASCT or CAR T-cell Therapy in Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

B-Cell Non-Hodgkin Lymphoma

United States
University of Texas Southwestern Medical Center
Merck Sharp & Dohme LLC

Recruiting

Muscle Relaxation for Pediatric Adenotonsillectomy

Tonsillectomy

United States
Jason Chui

Recruiting

Cerebral Flow-metabolism Coupling During Adult Surgery

Anesthesia

Canada
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Effects and Safety of Sacubitril/Valsartan on Refractory Hypertension

Resistant Hypertension

China
Minia University

Recruiting

Can Dexmedetomidine With Hyalase Augment Quality and Duration of Analgesia When Added to Lumbar Epidural Steroid in Failed Back Surgery. Randomized Double Blind Study

Pain, Neuropathic

Egypt
Mansoura University

Not yet recruiting

Effect of Local Anesthesia Versus Induced Hypotensive Anesthesia on Quality of External Dacryocystorhinostomy Operation

Patient With Nasolacrimal Duct Obstruction | External Dacryocystorhinostomy Operation

Egypt
Ottawa Hospital Research Institute
University of Ottawa; The Canadian College of Naturopathic Medicine; Lotte &... and other collaborators

Recruiting

The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage II (POISE)

Gastric Cancer | Esophageal Cancer | Lung Cancer

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Pathologic Stage IB Esophageal Adenocarcinoma AJCC v8 | Pathologic... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Recurrent Hepatocellular Carcinoma | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Refractory Liver Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Durvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Colorectal Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7

United States, Canada
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Rutgers Cancer Institute...

Active, not recruiting

Pembrolizumab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-IIIB Non-Small Cell Lung Cancer

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Stage II Non-Small Cell Lung Cancer

United States
Jonsson Comprehensive Cancer Center
AstraZeneca

Terminated

Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Radiation Therapy and Capecitabine With or Without Curcumin Before Surgery in Treating Patients With Rectal Cancer

Recurrent Rectal Carcinoma | Stage IIIA Rectal Cancer AJCC v7 | Stage IIIB Rectal Cancer AJCC v7 | Stage IIIC Rectal Cancer AJCC v7 | Rectal Mucinous Adenocarcinoma | Rectal Signet Ring Cell Adenocarcinoma | Stage IIA Rectal Cancer AJCC v7 | Stage IIB Rectal Cancer AJCC v7 | Stage IIC Rectal Cancer...

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar Cancers

Vaginal Squamous Cell Carcinoma, Not Otherwise Specified | Recurrent Cervical Carcinoma | Advanced Cervical Adenocarcinoma | Human Papillomavirus-Related Cervical Squamous Cell Carcinoma | Human Papillomavirus-Related Vulvar Squamous Cell Carcinoma | Stage III Cervical Cancer AJCC v8 | Stage IIIA... and other conditions

United States
University of Washington
National Cancer Institute (NCI); AstraZeneca

Terminated

Durvalumab, Tremelimumab and Hypofractionated Radiation Therapy in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Gliosarcoma | Supratentorial Glioblastoma

United States
Hanmi Pharmaceutical Company Limited

Completed

Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease

Hypertension | Aortic Stenosis | Aortic Regurgitation | Left Ventricular Hypertrophy | LVM

Korea, Republic of
Hackensack Meridian Health

Terminated

In-vivo Regulatory T Cell Enhancement With Cyclophosphamide and Sirolimus (T-REG)

Graft Versus Host Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Cancer Prevention Research Institute of Texas

Completed

Fucosylated T Cells for Graft Versus Host Disease (GVHD) Prevention

Lymphoma | Leukemia

United States

Search clinical trials for: Protease Inhibitors

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations