Search clinical trials for: rAAV2/5-PBGD vector dosage 4

Total 111 results

Digna Biotech S.L.
University of Navarra; Porphyria Centre Sweden; UniQure N.V.; Nationales Centrum...

Completed

Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treatment of Acute Intermittent Porphyria

Acute Intermittent Porphyria

Spain
Affiliated Hospital of Guangdong Medical University

Not yet recruiting

Safety and Efficacy Clinical Study of Severe Hemophilia B Treatment With KL001

Hemophilia B Without Inhibitor
Zhejiang University

Not yet recruiting

Safety and Efficacy Clinical Study of Severe Hemophilia B Treatment With KL001

Hemophilia B Without Inhibitor
Affiliated Hospital of Guangdong Medical University

Not yet recruiting

Safety and Efficacy Clinical Study of KL-HIV-Tri01 in the Treatment of HIV Infected Subjects

HIV Infections
BioNTech SE
Pfizer

Withdrawn

A Study to Learn About Bivalent COVID-19 RNA Vaccine Candidate(s) in Healthy Infants and Children

COVID-19
Innovent Biologics (Suzhou) Co. Ltd.

Completed

A Study to Investigate the Pharmacokinetic/Pharmacodynamic Characteristics of IBI128(A New Xanthine Oxidase Inhibitor)

Gout Arthritis

China
Pfizer

Completed

STUDY OF PF-07321332 IN HEALTHY PARTICIPANTS

Healthy Participants

United States, Belgium
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.
Sponsor GmbH

Completed

A Clinical Trial of Freeze-dried Human Rabies Vaccine (MRC-5 Cells)

Rabies Vaccine Adverse Reaction

China
Ningbo Rongan Biological Pharmaceutical Co., Ltd.

Not yet recruiting

Clinical Trial of Freeze-dried Human Rabies Vaccine (Without Serum Vero Cells)

Rabies

China
Pennington Biomedical Research Center
National Center for Complementary and Integrative Health (NCCIH); Office of...

Completed

Evaluation of Soy-protein Russian Tarragon (Artemisia Dracunculus L.) (RT2)

Diabetes Prevention

United States
Taiho Pharmaceutical Co., Ltd.

Recruiting

A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria

Chronic Spontaneous Urticaria

Japan
Novo Nordisk A/S

Completed

A Research Study Looking at the Comparability of 2 Different Forms of Oral Semaglutide in Healthy People

Type 2 Diabetes | Healthy Volunteers

United States, Canada
Zhongnan Hospital
Institute of Biotechnology, Academy of Military Medical Sciences, PLA of...

Recruiting

A Clinical Trial on Booster Immunization of Two COVID-19 Vaccines Constructed From Different Technical Routes

COVID-19

China
Edgewise Therapeutics, Inc.

Recruiting

A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX) (LYNX)

Duchenne Muscular Dystrophy

United States
Pulmongene Ltd.

Completed

A First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of PMG1015

Idiopathic Pulmonary Fibrosis

Australia
Rennes University Hospital

Completed

Evaluation of the Effect of Dextran Sulphate on Anti-Xa Activities Measured (DEXHEP)

Unfractionated Heparin Treatment

France
Oasis Pharmaceuticals, LLC
Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases...

Recruiting

Safety Study of OA-235i in Subjects With Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis | Nonalcoholic Fatty Liver

United States
BioNTech SE
Pfizer

Recruiting

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

COVID-19 | Severe Acute Respiratory Syndrome Coronavirus 2 | SARS-CoV-2 Virus

United States, Brazil, Puerto Rico
Pfizer

Completed

Study to Assess Safety, Tolerability and Pharmacokinetics of APX001 Administered by Intravenous Infusion to Healthy Subjects

Fungal Infection

Netherlands
CohBar, Inc.

Completed

A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease

United States
Sun Pharma Advanced Research Company Limited

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SPARC1316

Asthma

United Kingdom
Menarini Group

Completed

Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee (ALBATROSS-3)

Knee Osteoarthritis

United States, Italy, Germany, Czech Republic
Novo Nordisk A/S

Completed

A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity

Obesity

Germany
Biocad

Completed

Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 in Healthy Volunteers

Healthy

Russian Federation
QurAlis Corporation

Recruiting

A Study Evaluating the Safety and Tolerability of QRL-201 in ALS

Amyotrophic Lateral Sclerosis

Canada, Germany, Netherlands, Ireland, United Kingdom, Belgium
Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd.

Recruiting

A Clinical Trial of Freeze-dried Human Rabies Vaccine (Vero Cells)

Safety and Efficacy | Rabies Vaccine Adverse Reaction

China
Janssen Research & Development, LLC

Completed

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-55375515 in Healthy Male Participants

Healthy

Netherlands
Janssen Research & Development, LLC

Active, not recruiting

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease (GALAXI)

Crohn's Disease

United States, Israel, Japan, Belgium, Lebanon, Taiwan, Netherlands, Russian Federation, Korea, Republic of, Jordan, France, Portugal, Turkey, Greece, Canada, Germany, Malaysia, Belarus, Latvia, Poland, Australia, Italy, Croatia, China, United Kingdom and more
BioMarin Pharmaceutical

Recruiting

A Gene Therapy Study of BMN 331 in Subjects With Hereditary Angioedema (HAErmony-1)

Hereditary Angioedema | HAE

United States, Spain, Australia
University Hospital, Ghent

Completed

Sevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid Tolerance

Anesthesia

Belgium
Lidian Chen
Peking University Third Hospital

Not yet recruiting

Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment

Mild Cognitive Impairment
Bayer

Completed

Study to Assess the Safety, Tolerability, Effects on the Body, Absorption, Distribution and Elimination of 25 mg BAY2433334 in Renal Impairment Including Renal Replacement Therapy ("Dialysis")

Prevention of Thromboembolic Events

Germany
Octapharma

Completed

Study of Octaplex, a Four-factor Prothrombin Complex Concentrate (4F-PCC) and Beriplex® P/N (Kcentra) for the Reversal of Vitamin K Antagonist (VKA) Induced Anticoagulation in Patients Needing Urgent Surgery With Significant Bleeding Risk.

Significant Bleeding Risk

Russian Federation, United States, Romania, Ukraine, Belarus, Bulgaria, Georgia, Germany, Moldova, Republic of, Poland, Spain
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Doses of LP-003 in Healthy Adult Participants

Chronic Spontaneous Urticaria

China
Janssen Research & Development, LLC

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of JNJ-64991524 in Healthy Participants

Healthy

Belgium
Longbio Pharma

Active, not recruiting

A Study of Single and Multiple Dose Administration of LP-001 in Healthy Subjects

Myelodysplastic Syndrome (MDS)

China
Longbio Pharma

Recruiting

A Study of Single and Multiple Doses of LP-005 in Healthy Adult Participants

Paroxysmal Nocturnal Hemoglobinuria (PNH)

China
Ikena Oncology
Gilead Sciences

Terminated

A Phase 1a/1b FIH Study of PY159 and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Breast Cancer | Head and Neck Cancer | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Gastric Adenocarcinoma | Lung Adenocarcinoma | Advanced Solid Tumor

United States
LTN PHARMACEUTICALS, INC.

Completed

ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer (ARMOR1)

Prostate Cancer

United States
Stragen France

Completed

First-In-Human PainCart Study for STR-324

Pain

Netherlands
Radicle Science

Active, not recruiting

Radicle Clarity: A Study of Health and Wellness Products on Mental Clarity and Health Outcomes

Cognitive Function

United States
Hellenic Oncology Research Group

Terminated

Bevacizumab in Combination With Chemotherapy in the Neo-adjuvant Setting for HER2 (-) Breast Cancer

Breast Cancer

Greece
Auro Vaccines LLC
United States Department of Defense; Accelovance

Completed

Trial to Evaluate Safety and Immunogenicity of an Ebola Zaire Vaccine in Healthy Adults

Ebola Virus Disease

United States
GlaxoSmithKline

Recruiting

A Study to Find and Confirm the Dose and Assess Safety, Reactogenicity and Immune Response of a Vaccine Against Pandemic H5N1 Influenza Virus in Healthy Younger and Older Adults

Influenza, Human

United States
Boehringer Ingelheim

Completed

Pharmacodynamics, Safety and Pharmacokinetics After Oral Administration of BIBR 1048 MS in Healthy Volunteers

Healthy
Kasr El Aini Hospital

Completed

Low Dose Tadalafil for Treatment of Female OAB Syndrome: Short Term Follow up.

Female Patients With Overactive Bladder Syndrome or Female Patients With Urgency or Urgency Urinary Incontinence

Egypt
NRG Oncology
National Cancer Institute (NCI)

Withdrawn

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

Glioblastoma | Anaplastic Astrocytoma | Oligodendroglioma | Supratentorial Glioblastoma
Guangdong Raynovent Biotech Co., Ltd

Completed

The Safety, Tolerability and Pharmacokinetics Study of RAY1216 in Healthy Adult Participants

COVID-19 (Coronavirus Disease 2019)

China
Amsterdam UMC, location VUmc

Completed

High Dose Rate Brachytherapy for Treatment of Keloids

Keloid

Netherlands
Westlake Pharmaceuticals (Hangzhou) Co., Ltd.

Completed

Study of WPV01 in Healthy Subjects

Healthy Participants

China

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