Search clinical trials for: rifampicin

Total 472 results

Boehringer Ingelheim

Completed

A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 894416 in the Blood

Healthy

Germany
Rennes University Hospital

Completed

EVRIOS : Comparative Evaluation of Low Versus High Doses of Rifampicin (EVRIOS)

Osteoarticular Infection

France
AstraZeneca

Completed

A Study in Healthy Subjects to Assess the Pharmacokinetics of Savolitinib When Administered Alone and in Combination With Rifampicin

Solid Tumors

United States
Jiangsu HengRui Medicine Co., Ltd.

Completed

A Drug-drug Interaction Trial of Rifampicin Pharmacokinetics Effect on Fluzoparib

Healthy Male Subjects

China
University of Oulu
Oulu University Hospital

Completed

The Effect of PXR Activation on Blood Pressure Regulation

Blood Pressure Regulation

Finland
Hadassah Medical Organization

Unknown

Genetic Variability in the Response to Warfarin at Baseline and During Induction of CYP2C9

Healthy Subjects

Israel
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Tuberculosis Infection | Pediatric HIV Infection

Nigeria
Jiangsu HengRui Medicine Co., Ltd.

Completed

Effect of Rifampicin on the Pharmacokinetics of HRS-1167 in Healthy Subjects

Advanced Solid Tumor

China
Institute of Tropical Medicine, Belgium
Leiden University Medical Center; Damien Foundation; Instituto Fernandes Figueira and other collaborators

Completed

Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar (PEOPLE)

Leprosy

Comoros, Madagascar
Shanghai Public Health Clinical Center

Completed

The Drug Interaction Between Albuvirtide (ABT) and Rifampin（RIF） in Healthy Adult Subjects

Drug Interaction

China
Eli Lilly and Company

Completed

A Study of Baricitinib and Rifampicin in Healthy Participants

Healthy Volunteers

United Kingdom
National University Hospital, Singapore

Suspended

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Rifampicin in Healthy Volunteers

Tuberculosis

Singapore
Hoffmann-La Roche

Completed

A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers

Healthy Volunteer

United Kingdom
AstraZeneca

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Selumetinib in Healthy Male Volunteers

Solid Tumours

United States
Michael Hoelscher
Quintiles, Inc.; German Federal Ministry of Education and Research; Parexel; European... and other collaborators

Completed

Early Bactericidal Activity (EBA) of SQ109 in Adult Subjects With Pulmonary TB (SQ109EBA)

Tuberculosis, Pulmonary

South Africa
AstraZeneca

Completed

Effects of Administration of Fostamatinib on Blood Concentrations of Rifampicin in Healthy Subjects.

Rheumatoid Arthritis | Healthy Volunteers

United States
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Completed

A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy Volunteers

Healthy Volunteers

China
Boehringer Ingelheim

Completed

Drug-drug Interaction Trial Between Rifampicin and BI 409306 in Healthy Volunteers

Healthy

Germany
Radboud University Medical Center
European and Developing Countries Clinical Trials Partnership (EDCTP); Department... and other collaborators

Completed

Safety, Tolerability, Extended Early Bactericidal Activity and PK of Higher Doses Rifampicin in Adults With Pulmonary TB (HR1)

Pulmonary Tuberculosis (TB)

South Africa
Boehringer Ingelheim

Completed

Relative Bioavailability of a Single Dose of Nintedanib Given Alone and in Combination With Multiple Doses of Rifampicin

Healthy

Germany
Seoul National University Hospital

Completed

A Pilot Study for Pharmacokinetic Parameter of Colchicine in Patient Taking Rifampin

Tuberculosis | Chronic Kidney Disease
Damien Foundation
Institute of Tropical Medicine, Belgium; National TB control Programme Bangladesh

Completed

Optimization of the TB Treatment Regimen Cascade (OneRIF)

Tuberculosis, Pulmonary

Bangladesh
Leiden University Medical Center

Recruiting

MRSA Decolonization in Complicated Carriage (CLEANEST)

MRSA

Netherlands
Millennium Pharmaceuticals, Inc.
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

An Open-Label Study to Assess the Effect of CYP3A4 Induction on the Pharmacokinetics of VELCADE (Bortezomib)

Multiple Myeloma | Non-Hodgkin's Lymphoma

Israel, Italy, Poland, South Africa, United Kingdom
Hospital Universitari Vall d'Hebron Research Institute
Radboud University Medical Center; University Medical Center Groningen; Centro... and other collaborators

Not yet recruiting

Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (RIAlta)

Tuberculosis

Spain, Netherlands, Paraguay, Portugal
Suzhou Yabao Pharmaceutical R&D Co., Ltd.

Completed

A Drug Interaction Study of SY-004 Capsules in Healthy Subjects

Type 2 Diabetes

China
Idorsia Pharmaceuticals Ltd.

Completed

A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of Clazosentan

Healthy Subjects

Netherlands
Boehringer Ingelheim

Completed

DDI Strong CYP3A4 Inducer

Healthy

Germany
University of Oulu

Completed

Effects of Pregnane X Receptor (PXR) Activation on Human Glucose, Lipid and Hormone Homeostasis (Rifa-2)

Glucose Metabolism

Finland
Mahidol University

Unknown

Colistin Plus Rifampicin in MDR P. Aeruginosa and A. Baumanii

Drug Safety

Thailand
University of Oulu

Completed

Pregnane X Receptor (PXR) Agonist Rifampicin Effects on Glucose, Lipid and Hormone Homeostasis

Glucose Tolerance

Finland
Children's Hospital of Philadelphia
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Rifampin in CYP24A1-related Hypercalcemia and Hypercalciuria (RICHH)

Genetic Disease | Hypercalciuria | Idiopathic Infantile Hypercalcemia - Mild Form | Idiopathic Infantile Hypercalcaemia - Severe Form | Hypercalcemia, Idiopathic, of Infancy | Hypercalciuric Hypercalcemia

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Investigate the Effect of Rifampicin on the Uptake and Breakdown of ACT-246475 in Healthy Subjects

Healthy Subject

Netherlands
Global Alliance for TB Drug Development

Completed

PK Interaction Between Rifapentine or Rifampicin and a Single Dose of TMC207 in Healthy Subjects (TMC207-CL002)

Tuberculosis

United States
Eisai Limited

Completed

To Assess the Effect of Rifampicin on the Pharmacokinetics of Eribulin Mesylate in Participants With Advanced Solid Tumors

Tumor

Netherlands
Radboud University Medical Center
Sanofi; European and Developing Countries Clinical Trials Partnership (EDCTP); National Institute for Public Health and the Environment (RIVM) and other collaborators

Completed

Pharmacokinetics and Pharmacodynamics of High Versus Standard Dose Rifampicin in Patients With Pulmonary Tuberculosis (High RIF)

Tuberculosis

Tanzania
University of Campania "Luigi Vanvitelli"
Federico II University

Completed

Colistin and Rifampicin for MDR-Acinetobacter (CoRAb)

Pneumonia, Ventilator-Associated | Hospital Acquired Pneumonia | Infection Due to Resistant Bacteria | Infection of Bloodstream | Infectious Disease of Abdomen
British Thoracic Society

Completed

Clarithromycin v Ciprofloxacin Added to Rifampicin + Ethambutol, for Opportunist Mycobacterial Pulmonary Disease

Pulmonary Diseases

United Kingdom
Karolinska University Hospital
AstraZeneca

Completed

Cholesterol Metabolites as Markers for CYP3A Induction

CYP3A4 Induction

Sweden
Novartis

Completed

Effect of a Potent Inducer Rifampicin on the Pharmacokinetics of Deferasirox in Healthy Volunteers

Healthy
Beta Pharma, Inc.

Completed

A Phase I Study to Assess the Effect of Itraconazole and Rifampicin on Pharmacokinetics Profile of BPI-7711

NSCLC

China
Global Alliance for TB Drug Development

Completed

Shortening Treatment by Advancing Novel Drugs (STAND)

Tuberculosis, Pulmonary, Drug Sensitive | Tuberculosis, Pulmonary, Multi Drug-resistant

South Africa, Zambia, Georgia, Philippines, Kenya, Malaysia, Tanzania, Uganda
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

2R2: Higher Dose Rifampin for 2 Months vs Standard Dose Rifampin for Latent TB. (2R2)

Latent Tuberculosis

Canada, Indonesia, Vietnam
Kilimanjaro Clinical Research Institute
European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Evaluation of Pharmacokinetics and Safety Tolerability of Higher Doses of Rifampic (HighRif C)

Clinical Trial

Tanzania
Boehringer Ingelheim

Completed

Drug Interaction Study With Rifampicin and Afatinib

Healthy

Germany
Johns Hopkins University
University of Cape Town Lung Institute; University of Cape Town

Completed

Study of Daily Rifapentine for Pulmonary Tuberculosis

Tuberculosis

South Africa
Pontificia Universidad Catolica de Chile
Sociedad Chilena de Pediatría

Unknown

Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams

Respiratory Distress Syndrome

Chile
Assistance Publique - Hôpitaux de Paris

Completed

Pharmacological Interaction of Rifampicin on Clindamycin in Staphylococcic Osteoarticular Infections (DALARI)

Staphylococcal Infections

France
Centre Hospitalier Universitaire, Amiens

Terminated

Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation (ASPEN)

Acute Respiratory Distress Syndrome

France
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa, Philippines

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