Search clinical trials for: Saline placebo

Total 62832 results

Vanderbilt University Medical Center

Active, not recruiting

Intravenous (IV) Saline and Exercise in Postural Tachycardia Syndrome (POTS)

Postural Tachycardia Syndrome

United States
Children's Hospital Los Angeles
Thrasher Research Fund; UCSF Benioff Children's Hospital Oakland

Completed

Nebulized Hypertonic Saline for Bronchiolitis

Bronchiolitis

United States
University of Oxford
University of Birmingham

Terminated

MVA85A Aerosol vs Intramuscular Vaccination in Adults With Latent Mycobacterium Tuberculosis (M. tb) Infection

Tuberculosis

United Kingdom
University of Texas Southwestern Medical Center

Completed

Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis

Acute Bronchiolitis

United States
University of Michigan
Radiological Society of North America

Terminated

Double-Blind Placebo-Controlled CIN Trial

Acute Kidney Injury

United States
AstraZeneca
Gynecologic Oncology Group Foundation; European Network for Gynaecological...

Recruiting

Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical) (eVOLVECervical)

Locally Advanced Cervical Cancer

Spain, Denmark, Italy, Korea, Republic of, Japan, Peru, China, Brazil, Taiwan, United States, Canada, Turkey, India, Poland, Mexico, Puerto Rico, Norway
University of Cincinnati
United States Department of Defense

Recruiting

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

Meniscus Tear

United States
Indiana Hand to Shoulder Center
CTM Biomedical

Enrolling by invitation

Efficacy of a Single Injection of CTM for Post-Operative CMC Arthritis (CTM CMC)

Osteoarthritis | Osteoarthritis Thumb Base Joint | Carpometacarpal Osteoarthritis | Thumb

United States
Dr. med. Mahir Karakas

Completed

Adrecizumab in Cardiogenic Shock (ACCOST-HH)

Endothelial Dysfunction | Cardiogenic Shock

Germany
Noveome Biotherapeutics, formerly Stemnion

Terminated

Study of ST266 in Diabetic Subjects With Deep Burns Managed With Skin Grafts

Diabetes | Third Degree Burns

United States
Innate Immunotherapeutics
Syneos Health

Completed

Safety and Efficacy Study of MIS416 to Treat Secondary Progressive Multiple Sclerosis

Secondary Progressive Multiple Sclerosis

New Zealand, Australia
Golden Jubilee National Hospital
NHS Lothian; Imperial College Healthcare NHS Trust

Unknown

Effects of Apelin on the Lung Circulation in Pulmonary Hypertension

Heart Failure | Pulmonary Arterial Hypertension

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Arthritis Research UK

Completed

Autologous Tolerogenic Dendritic Cells for Rheumatoid Arthritis (AutoDECRA) (AutoDECRA)

Rheumatoid Arthritis

United Kingdom
GlycoMimetics Incorporated

Completed

Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis

Sickle Cell Disease | Vaso-occlusive Crisis | Pain Crisis

United States, Canada
GlaxoSmithKline

Terminated

Multiple Doses of Anti-NOGO A in Relapsing Forms of Multiple Sclerosis

Multiple Sclerosis, Relapsing-Remitting

Italy, Norway
Meir Medical Center

Completed

Treatment of ATFL Tears With PRP

Soft Tissue Healing

Israel
Kuopio University Hospital

Withdrawn

Post-operative Corticosteroid Treatment After Mitral Valve Surgery (MitralPOCS)

Atrial Fibrillation

Finland
University Hospitals Cleveland Medical Center

Completed

Nebulized Hypertonic Saline for Mechanically Ventilated Children

Respiratory Failure

United States
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Avidity Biosciences, Inc.

Active, not recruiting

Extension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients (MARINA-OLE)

Nervous System Diseases | Genetic Diseases, Inborn | Musculoskeletal Diseases | Muscular Diseases | Neuromuscular Diseases | Neurodegenerative Diseases | Muscular Dystrophies | Muscular Disorders, Atrophic | Heredodegenerative Disorders, Nervous System | Myotonic Dystrophy | Myotonic Disorders | Myotonic Dystrophy... and other conditions

United States
Cidara Therapeutics Inc.
Janssen Pharmaceuticals

Active, not recruiting

Study of CD388 Intramuscular or Subcutaneous Administration in Healthy Subjects

Healthy

United States
West Virginia University

Completed

Does Fluid Replacement From Preoperative NPO Status Improve Postoperative Recovery (Hydration)

Osteoarthritis

United States
Barrow Neurological Institute
Massachusetts General Hospital; Genentech, Inc.; ALS Association; Barrow Neurological...

Completed

A Trial of Tocilizumab in ALS Subjects (TCZALS-001)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | ALS | Lou Gehrig's Disease

United States
Arthrex, Inc.

Completed

Autologous Conditioned Plasma (ACP) Intra-articular (IA) Injections for Knee Osteoarthritis (OA)

Osteoarthritis

United States
TrueBinding, Inc.

Recruiting

Sequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects (TB006SAD)

Alzheimer Disease

United States
Cidara Therapeutics Inc.
Janssen Pharmaceuticals

Completed

Study of CD388 Subcutaneous Administration in Healthy Japanese Subjects

Healthy

United States
ReAlta Life Sciences, Inc.

Completed

A Phase 1 SAD/MAD Study of RLS-0071 in Healthy Volunteers in Support of a COVID-19 Development Program

Healthy Volunteer

Canada
Alexion Pharmaceuticals
Syneos Health

Terminated

A Study of ALXN1830 in Healthy Adult Participants

Healthy

New Zealand
Alkahest, Inc.

Completed

A Study to Assess the Safety of GRF6019 Infusions in Subjects With Severe Alzheimer's Disease

Severe Alzheimer Disease

United States
MiMedx Group, Inc.

Completed

Protocol for the Clinical Evaluation of Lyophilized Amniotic Fluid in the Treatment of Knee Osteoarthritis

Osteoarthritis, Knee

United States
MenoGeniX, Inc.
National Institutes of Health (NIH); National Institute on Aging (NIA)

Completed

A Study of the Safety and Effect of Repeated Administration of G-CSF on Hot Flashes in Postmenopausal Women

Postmenopausal Symptoms

United States
Avidity Biosciences, Inc.

Recruiting

Study of AOC 1044 in Healthy Adult Volunteers and Participants With Duchenne Muscular Dystrophy (DMD) Mutations Amenable to Exon 44 Skipping (EXPLORE44)

Duchenne Muscular Dystrophy | Exon 44

United States
Danish Headache Center

Recruiting

Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache

Post-Traumatic Headache

Denmark
Amgen

Terminated

Study of Daxdilimab (HZN-7734) in Participants With Active Proliferative Lupus Nephritis (LN)

Lupus Nephritis

Spain, Brazil, Taiwan, Thailand, Croatia, Serbia, United States, Malaysia, Poland, Philippines, Argentina, Israel
Faraday Pharmaceuticals, Inc.

Completed

A Study of Acute Myocardial Infarction Using FDY-5301

Acute Myocardial Infarction | STEMI

United Kingdom, United States, Hungary, Poland
University Hospital, Gentofte, Copenhagen

Completed

Dasiglucagon in the Treatment of Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass

Hyperinsulinemic Hypoglycemia | Postprandial Hypoglycemia

Denmark
Kevin Flanigan

Withdrawn

Gene Transfer Clinical Trial for Duchenne Muscular Dystrophy Using rAAVrh74.MCK.GALGT2

Duchenne Muscular Dystrophy

United States
University of Utah
Novartis Pharmaceuticals

Completed

A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab

Esophagitis

United States
ADARx Pharmaceuticals, Inc.

Recruiting

Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients

Hereditary Angioedema

Australia
Revimmune
C.R.O. ReSolution Latin America S.A.

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic pAtients With COVID-19 Infection (Brazil Cohort) (ILIAD-7-BRA)

COVID-19 | Lymphocytopenia

Brazil
Revimmune
M.D. Anderson Cancer Center; Memorial Sloan Kettering Cancer Center; Cancer Research... and other collaborators

Terminated

InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O ) (ILIAD-7-US-O)

COVID-19 | Lymphocytopenia

United States
Ben-Gurion University of the Negev

Terminated

Intraarticular Ozone Therapy for Pain Control in Osteoarthritis of the Knee

Osteoarthritis of the Knee

Israel
Barry Borlaug

Completed

Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction

Heart Disease | Pulmonary Hypertension | Heart Failure With Preserved Ejection Fraction | Exercise Intolerance

United States
Hadassah Medical Organization

Completed

Beta Glucosylceramide for Treatment of NASH

Compliance Behavior
Children's Hospital Medical Center, Cincinnati
Johns Hopkins Bloomberg School of Public Health; Bill and Melinda Gates Foundation and other collaborators

Completed

Field Trial of Maternal Influenza Immunization in Asia (Mothers'Gift)

Influenza Human

Nepal
ADARx Pharmaceuticals, Inc.
ADARx Australia Pty Ltd

Recruiting

Safety, Tolerability, PK and PD of ADX-038 in HV and Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Australia
MitoImmune Therapeutics

Recruiting

Evaluate the Safety and Efficacy for Oral Mucositis Prevention of MIT-001 in Auto HSCT (Capella)

Lymphoma | Multiple Myeloma | Oral Mucositis | Hematologic Cancer

Korea, Republic of
GeneOne Life Science, Inc.

Not yet recruiting

GLS-1200 Topical Nasal Spray to Prevent Sinusitis After Endoscopic Sinus Surgery

Sinusitis Chronic

United States
Merck Sharp & Dohme LLC

Completed

Single Dose Study of MK-2060 to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Older Japanese Participants on Dialysis (MK-2060-012)

Kidney Failure, Chronic | End-Stage Renal Disease (ESRD) | End-Stage Kidney Disease (ESKD)

Japan
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Emapalumab in Japanese Healthy Volunteers.

Rare Diseases

Japan

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