Search clinical trials for: simvastatin, placebo

Total 54343 results

Lund University

Recruiting

Treatment of Graves´Ophthalmopathy With Simvastatin (GO-S)

Graves Ophthalmopathy | Thyroid Associated Ophthalmopathy | Thyroid Associated Orbitopathy

Sweden
Mitsubishi Tanabe Pharma Corporation

Completed

A Study to Investigate the Effect of MT-8554 on the Pharmacokinetics of Simvastatin and Rosuvastatin in Healthy Subjects

Healthy

United Kingdom
Brasilia Heart Study Group
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Fundação de Amparo...

Completed

Simvastatin and Diastolic Dysfunction

Hypertension | Diastolic Dysfunction

Brazil
Poznan University of Medical Sciences
Yale University

Unknown

Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.

Polycystic Ovary Syndrome

Poland
Thammasat University

Completed

Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS

Ischemic Stroke
Brigham and Women's Hospital

Completed

Effect of Statin Use on Aldosterone Secretion

Healthy Subjects

United States
Organon and Co

Completed

Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)

Hypercholesterolemia
Chinese University of Hong Kong

Completed

Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and Rosuvastatin

Hypercholesterolemia

Hong Kong
Organon and Co

Completed

Study To Assess The Efficacy Of A Cholesterol Lowering Drug On Top Of Statins In Patients After Myocardial Infarction (MI)(0653A-150)

Cardiovascular Disorder
Organon and Co

Completed

An Extension Study of An Investigational Drug in Patients With Hypercholesterolemia (0653A-038)(COMPLETED)

Hypercholesterolemia
National Cancer Center, Korea

Completed

Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC)

Lung Cancer

Korea, Republic of
Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
Provident Clinical Research
Reliant Pharmaceuticals

Unknown

An Open-Label Extension to Assess the Continued Efficacy of Omacor Plus Simvastatin

Mixed Dyslipidemia
Organon and Co

Completed

A Study to Assess the Cholesterol Lowering Effect of an Ezetimibe/Simvastatin Combination Tablet Compared to Another Cholesterol Lowering Drug in Patients With High Cholesterol and With High Cardiovascular Risk (0653A-809)(COMPLETED)

Hypercholesterolemia
University of California, Davis

Withdrawn

Trial of Simvastatin for the Treatment of Severe Asthma

Severe Asthma

United States
Organon and Co

Completed

Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)

Hypercholesterolemia
University of Chicago
GlaxoSmithKline

Completed

A Study for Pre-diabetic Patients With Cholesterol Lowering Drugs (SIROCO)

Pre-diabetes

United States
Organon and Co

Completed

Ezetimibe/Simvastatin in Patients With Metabolic Syndrome (0653A-107)(COMPLETED)

Metabolic Syndrome | Hypercholesterolemia
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Not yet recruiting

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
University of Kansas Medical Center
University of Missouri-Columbia; American Heart Association

Completed

Exercise, Statins, and the Metabolic Syndrome

Metabolic Syndrome | Obese | Sedentary

United States
Medical University of Vienna
Merck Sharp & Dohme LLC; European Foundation for the Study of Diabetes; Austrian... and other collaborators

Completed

Does Simvastatin Affect Insulin Sensitivity in Dyslipidemic Type 2 Diabetic Patients?

Cardiovascular Disease | Diabetes | Hypercholesterolemia

Austria
Organon and Co
Merck Sharp & Dohme LLC

Completed

Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)

Hypercholesterolemia | Hyperlipidemia
International Bio service

Not yet recruiting

Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
GlaxoSmithKline

Completed

Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects

Hypertriglyceridemia

United States
Organon and Co

Completed

A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042)

Hypercholerolemia
University of Louisville
James Graham Brown Cancer Center

Terminated

Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

Multiple Myeloma

United States
Leiden University Medical Center

Unknown

Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Netherlands
Novartis

Completed

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Dyslipidemia

Germany, Switzerland
US Department of Veterans Affairs
University of Pittsburgh

Completed

Systematic Management of High Cholesterol Utilizing Computer Monitoring

Hypercholesterolemia

United States
Organon and Co

Completed

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Hypercholesterolemia
GlaxoSmithKline

Completed

A Study To Evaluate The Safety And Tolerability Of SB-656933-AAA Following Repeated Doses In Healthy Adult Subjects

Pulmonary Disease, Chronic Obstructive

United Kingdom
Mayo Clinic

Completed

Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery

Perioperative Inflammatory Response

United States
Islamic Azad University, Tehran

Completed

Effects of Simvastatin in the Prevention of Pain Experienced After Tooth Extraction

Pain

Iran, Islamic Republic of
Boehringer Ingelheim

Completed

Drug-drug Interaction of Empagliflozin (BI 10773) and Simvastatin

Healthy

Germany
Leiden University Medical Center

Unknown

Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Netherlands
Jinnah Sindh Medical University
Al Khidmat Hospital Nazimabad Karachi; Medics Laboratories (Pvt.) Ltd.

Completed

Protective Effect of Zingiber Officinale L. Extract in Hypertensive Patients

The Main Focus of This Study is to Evaluate the Safety of Zingiber Officinale L. Tablets as Hypolipidemic Agent in Hypertensive Patients

Pakistan
Organon and Co

Completed

Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)

Coronary Disease | Hypercholesterolemia | Atherosclerotic Disease
Organon and Co

Completed

Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)

Hypercholesterolemia
Novartis

Completed

A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemia

HYPERTENSION | HYPERCHOLESTEROLEMIA

United States
Novartis

Completed

A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia

Hypercholesterolemia | Essential Hypertension

Switzerland, Germany
Mahidol University

Completed

The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids in Asthma

Asthma

Thailand
Federal University of São Paulo

Completed

Effect of Simvastatin and Ezetimibe on Lipid and Inflammation

Inflammation | Hypercholesterolemia | Cardiovascular Risk | Prediabetes

Brazil
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Organon and Co

Completed

Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018)

Familial Hypercholesterolemia
Massachusetts General Hospital

Terminated

Simvastatin Augmentation of Lithium Treatment in Bipolar Depression

Bipolar Disorder

United States
Anna Tsakiri
Sanofi

Withdrawn

Simvastatin as an add-on Treatment to Copaxone for the Treatment of Relapsing Multiple Sclerosis

Relapsing Remitting Multiple Sclerosis

Denmark
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Recruiting

Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
Korea University Guro Hospital

Completed

Drug Interaction Study of Simvastatin and Dabigatran

Healthy

Korea, Republic of
Boehringer Ingelheim

Completed

Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and Hypercholesterolemia

Hypertension | Dyslipidemias

Taiwan, Netherlands, Czech Republic, France, Germany, Hong Kong, Korea, Republic of, Russian Federation, Slovakia, South Africa, Sweden, Ukraine

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