Search clinical trials for: Simvastatin

Total 603 results

Mayo Clinic

Completed

Statin Interchange by Pharmacist Collaborative Practice Agreement (CPA)

Hypercholesterolemia

United States
Provident Clinical Research
Reliant Pharmaceuticals

Unknown

An Open-Label Extension to Assess the Continued Efficacy of Omacor Plus Simvastatin

Mixed Dyslipidemia
Organon and Co

Completed

Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)

Hypercholesterolemia
Organon and Co

Completed

A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)

Hypercholesterolemia
Chinese University of Hong Kong

Completed

Genome-wide Analysis of Lipid-lowering Efficacy and Drug Level of Simvastatin and Rosuvastatin

Hypercholesterolemia

Hong Kong
Novartis Pharmaceuticals

Completed

Safety, Pharmacokinetics and Pharmacodynamics of LGT209 in Healthy Volunteers With Elevated Cholesterol and in Hypercholesterolemic Patients Treated With Statins

Hypercholesterolemia | LDL Cholesterol

United States
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Not yet recruiting

Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
University of Kansas Medical Center
University of Missouri-Columbia; American Heart Association

Completed

Exercise, Statins, and the Metabolic Syndrome

Metabolic Syndrome | Obese | Sedentary

United States
Organon and Co
Merck Sharp & Dohme LLC

Completed

Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2)

Hypercholesterolemia | Hyperlipidemia
University of Oxford
Merck Sharp & Dohme LLC

Completed

Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH)

Cardiovascular Disease

United Kingdom
Organon and Co

Completed

Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)

Hypercholesterolemia
International Bio service

Not yet recruiting

Bioequivalence Study of Simvastatin 40 mg Film-coated Tablets in Healthy Thai Volunteers

Healthy Volunteer
University of California, San Diego
American Heart Association

Completed

Effects of Epicatechin on Statins for Mitochondrial Dysfunction and Impaired Exercise Capacity

Statin Intolerance

United States
GlaxoSmithKline

Completed

Open-Label Extension of a Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of Lovaza® and Simvastatin Therapy in Hypertriglyceridemic Subjects

Hypertriglyceridemia

United States
Organon and Co

Completed

Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial (0653-151)

Hypercholesterolemia
Merck Sharp & Dohme LLC

Completed

MK-0524B Lipid Study (MK-0524B-063)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Novartis

Completed

Efficacy of Fluvastatin and Fenofibrate in Comparison to Simvastatin and Ezetimibe in Patients With Metabolic Syndrome

Dyslipidemia

Germany, Switzerland
US Department of Veterans Affairs
University of Pittsburgh

Completed

Systematic Management of High Cholesterol Utilizing Computer Monitoring

Hypercholesterolemia

United States
Organon and Co

Completed

A Study to Evaluate Ezetimibe in Korean Patients With Primary Hypercholesterolemia (0653-042)

Hypercholerolemia
University of Louisville
James Graham Brown Cancer Center

Terminated

Overcoming Chemotherapy Resistance In Refractory Multiple Myeloma With Simvastatin and Zoledronic Acid

Multiple Myeloma

United States
Government Dental College and Research Institute...

Completed

1.2% Atorvastatin and 1.2% Simvastatin in Treatment of Chronic Periodontitis

Chronic Periodontitis
Leiden University Medical Center

Unknown

Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Netherlands
Fasa University of Medical Sciences
Shiraz University of Medical Sciences

Completed

Effects of Metformin Plus Simvastatin on Polycystic Ovarian Syndrome (PCOS): A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

Polycystic Ovary Syndrome

Iran, Islamic Republic of
Islamic Azad University, Tehran

Completed

Effects of Simvastatin in the Prevention of Pain Experienced After Tooth Extraction

Pain

Iran, Islamic Republic of
Boehringer Ingelheim

Completed

Drug-drug Interaction of Empagliflozin (BI 10773) and Simvastatin

Healthy

Germany
Leiden University Medical Center

Unknown

Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer

Colorectal Cancer

Netherlands
Jinnah Sindh Medical University
Al Khidmat Hospital Nazimabad Karachi; Medics Laboratories (Pvt.) Ltd.

Completed

Protective Effect of Zingiber Officinale L. Extract in Hypertensive Patients

The Main Focus of This Study is to Evaluate the Safety of Zingiber Officinale L. Tablets as Hypolipidemic Agent in Hypertensive Patients

Pakistan
Organon and Co

Completed

Cholesterol Lowering Level of MK0653A+Simvastatin in Patients With Hypercholesterolemia and Atherosclerotic or Coronary Vascular Disease (0653A-806)(COMPLETED)

Coronary Disease | Hypercholesterolemia | Atherosclerotic Disease
Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Organon and Co

Completed

Study to Evaluate the Cholesterol Lowering Effects of Two Marketed Drugs in Patients With Elevated Cholesterol Levels (0653A-058)

Hypercholesterolemia
Novartis

Completed

A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemia

HYPERTENSION | HYPERCHOLESTEROLEMIA

United States
Novartis

Completed

A Study to Evaluate the Efficacy of Valsartan/Simvastatin Combinations in Patients With Both Essential Hypertension and Hypercholesterolemia

Hypercholesterolemia | Essential Hypertension

Switzerland, Germany
Mahidol University

Completed

The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids in Asthma

Asthma

Thailand
Federal University of São Paulo

Completed

Effect of Simvastatin and Ezetimibe on Lipid and Inflammation

Inflammation | Hypercholesterolemia | Cardiovascular Risk | Prediabetes

Brazil
Shanghai Pulmonary Hospital, Shanghai, China
Chinese Academy of Sciences

Recruiting

Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy

Small Cell Lung Cancer

China
Korea University Guro Hospital

Completed

Drug Interaction Study of Simvastatin and Dabigatran

Healthy

Korea, Republic of
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy) (ODYSSEY FH II)

Heterozygous Familial Hypercholesterolemia

United Kingdom, Netherlands, Czech Republic, Norway
Boehringer Ingelheim

Completed

Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and Hypercholesterolemia

Hypertension | Dyslipidemias

Taiwan, Netherlands, Czech Republic, France, Germany, Hong Kong, Korea, Republic of, Russian Federation, Slovakia, South Africa, Sweden, Ukraine
Samsung Medical Center

Completed

Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC)

Metastatic Colorectal Cancer

Korea, Republic of
Mario Pérez Sayáns
Universidad de Murcia

Recruiting

Osteogenic Action of a Biphasic Bioceramic With Statin in a Third Molar Extraction Model (Galibone)

Bone Loss | Regenerative Inflammation

Spain
Poznan University of Medical Sciences
University of California, San Diego

Unknown

Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients

PCOS, Insulin Resistance

Poland
Medical University of Silesia

Unknown

The Effects of Hypolipemic and Antidiabetic Treatment on Cytokines (MSF)

Inflammation | Diabetes | Dyslipidemia | Cytokines

Poland
Ache Laboratorios Farmaceuticos S.A.

Completed

Efficacy/Safety of Rosuvastatin+Ezetimibe in High Risk Patients With Primary Hypercholesterolemia/Mixed Dyslipidemia (LANCE)

Dyslipidemia | Hypercholesterolemia

Brazil
Alaa Hassan ElBaz

Unknown

Effect of Lipid Lowering Agents on Diabetic Retinopathy and Cardiovascular Risk of Diabetic Patients

Diabetic Retinopathy
Kos Pharmaceuticals

Completed

Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS)

Hypercholesterolemia
Chestnut Hill Health System

Completed

Statin Therapy Vs. Therapeutic Lifestyle Changes and Supplements

Hyperlipidemia
Merck Sharp & Dohme LLC

Terminated

Efficacy and Safety of Extended-Release Niacin/ Laropiprant/Simvastatin Tablets in Participants With Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-143)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Cairo University

Recruiting

Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8

Periapical Periodontitis

Egypt
Organon and Co

Completed

A Study to Determine the Number of Patients Who Reach Optimal Cholesterol Levels on Each of Three Different Treatments (0653A-121)

Hypercholesterolemia
Judit Pich

Completed

Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development (2018-001698-25)

Liver Cirrhoses

Belgium, Spain, United Kingdom, Italy, Netherlands, France, Germany

3

Subscribe