Search clinical trials for: statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran

Total 36 results

Jena University Hospital

Not yet recruiting

Intensive Lipid-lowering in Patients With STEMI and NSTEMI (Germany on Target) (GoT)

ST Elevation Myocardial Infarction | Non-ST Elevation Myocardial Infarction | LDL-cholesterol

Germany
University Clinical Centre of Republic of Srpska

Recruiting

Low-density Lipoprotein Cholesterol Reduction With State-of-the-art Therapy in Secondary Prevention and Major Cardiovascular Adverse Events: Republic of Srpska Registry (RS-ACS)

Dyslipidemias | Acute Coronary Syndrome

Bosnia and Herzegovina
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Esperion Therapeutics, Inc.

Recruiting

Bempedoic Acid Pregnancy Surveillance Program

Pregnancy | Hyperlipidemias

United States
Esperion Therapeutics, Inc.

Completed

A Study Evaluating the Safety and Efficacy of Bempedoic Acid Plus Ezetimibe Fixed-Dose Combination Compared to Bempedoic Acid, Ezetimibe, and Placebo in Patients Treated With Maximally Tolerated Statin Therapy

Hyperlipidemias

United States
Federico II University

Recruiting

Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in Italy (AT-TARGET-IT)

Hypercholesterolemia

Italy
Esperion Therapeutics, Inc.

Completed

Milk-Only Lactation Study to Evaluate the Concentration of Bempedoic Acid and Bempedoic Acid/Ezetimibe Fixed Combination Drug Product (FCDP) in the Breast Milk of Healthy Lactating Women

Healthy Lactating Women

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg When Added to PCSK9 Inhibitor Therapy

Hypercholesterolemia

United States
Novartis Pharmaceuticals

Completed

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease (SIRIUS)

Atherosclerotic Cardiovascular Disease

France
Sanofi
Regeneron Pharmaceuticals

Completed

An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (ODYSSEY KIDS)

Hypercholesterolaemia

Norway, Russian Federation, Sweden, South Africa, Czechia, United States, Canada, France, Netherlands, Spain
Esperion Therapeutics, Inc.

Completed

Bempedoic Acid + Ezetimibe Fixed-Dose Combination (FDC) Study in Patients With Type 2 Diabetes and Elevated LDL-C

Diabetes Mellitus, Type 2 | Diabetes | Cholesterolemia

United States
NYU Langone Health

Completed

CHOlesterol Lowering and Residual Risk in Type 2 Diabetes (CHORD)

Type 2 Diabetes

United States
Kaiser Permanente
Esperion Therapeutics, Inc.

Not yet recruiting

Cholesterol Lowering Via Bempedoic Acid/Ezetimibe, an ACL-Inhibiting Regimen in Acute Coronary Syndrome Study

Cardiovascular Diseases | STEMI | NSTEMI

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Recruiting

Treatment With Bempedoic Acid and/or Its Fixed-dose Combination With Ezetimibe in Primary Hypercholesterolemia or Mixed Dyslipidemia (MILOS)

Hypercholesterolemia | Mixed Dyslipidemia

Austria, United Kingdom, Italy, Germany, Belgium
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Withdrawn

Treatment With Bempedoic Acid And/Or Its Fixed-dose Combination With Ezetimibe in Routine Clinical Practice in Patients With Primary Hypercholesterolemia Or Mixed Dyslipidemia (MILOS-Spain)

Mixed Dyslipidemia | Primary Hypercholesterolemia
Sanofi
Regeneron Pharmaceuticals

Completed

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

Dyslipidemia

United States, Australia, Brazil, Finland, Germany, Israel, Italy, Kuwait, Lebanon, Norway, Sweden, Switzerland, Turkey, United Arab Emirates, United Kingdom
Xuanwu Hospital, Beijing

Not yet recruiting

Short-term Effect of PCSK9 Inhibitor in Patients With Acute Ischemic Stroke

Acute Ischemic Stroke
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company
Daiichi Sankyo Germany

Completed

SurveY Followed by a Retrospective Chart Review to Describe the Key Factors Leading to Physician's Decision to Treat Patients at High and Very High Cardiovascular Risk With hyperchOlesterolemia or Mixed Dyslipidemia With NUSTENDI®

Hypercholesterolemia | Mixed Dyslipidemia

Germany
CHU de Quebec-Universite Laval
Canadian Institutes of Health Research (CIHR); Biovalorem

Active, not recruiting

Cholesterol Disruption in Combination With the Standard of Care in Patients With Advanced Pancreatic Adenocarcinoma

Pancreatic Cancer | Metastatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreas Cancer

Canada
University of Louisville

Recruiting

Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP) (ARTCAP)

Coronary Artery Disease | Atherosclerosis | Heart Attack

United States
Icahn School of Medicine at Mount Sinai

Completed

Rosuvastatin and Evolocumab for Coronary Artery Disease (Yellow V)

Coronary Artery Disease

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) 180mg, Ezetimibe 10mg, and Atorvastatin 20 mg Triplet Therapy in Patients With Elevated LDL-C

Hypercholesterolemia

United States
Esperion Therapeutics, Inc.

Completed

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

Atherosclerosis | Hypercholesterolemia | Statin Adverse Reaction

United States
Beijing Anzhen Hospital
Beijing Municipal Health Commission

Recruiting

Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis (EPISODE)

Aortic Stenosis

China
Wuhan Union Hospital, China

Recruiting

High-Resolution Assessment of Extracranial Plaques in a Multiple Centers Evolocumab Randomized Study

Cerebral Atherosclerosis

China
Yonsei University
Daewoong Pharmaceutical Co. LTD.

Recruiting

Effect of Early Initiation of Evolocumab on Lipid Profiles Changes in Patients With ACS Undergoing PCI (C-STAR)

Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia

Korea, Republic of
Food and Drug Administration (FDA)
Spaulding Clinical Research LLC

Completed

Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors

Healthy Subjects | Pharmacokinetics | Pharmacodynamics

United States
NYU Langone Health
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cholesterol Lowering and Residual Risk in Diabetes, Type 1 (CHORD1)

Type 1 Diabetes

United States
GWT-TUD GmbH

Active, not recruiting

Prospective German Very High Cardiovascular Risk Patients Dyslipidemia Treatment Indication Registry (PERI-DYS)

Dyslipoproteinemias

Germany
Brigham and Women's Hospital
Amgen

Recruiting

Lipid Management in Renal Transplant Recipients Using Evolocumab.

Hyperlipidemias

United States
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Lin Zhao

Recruiting

Effect of Evolocumab on Chronic Total Occlusions (EVOLO-CTO)

In-stent Restenosis | Major Adverse Cardiovascular Events

China
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia

Hypercholesterolemia

Slovenia, Taiwan, Russian Federation, Canada, Netherlands, Brazil, Denmark, Mexico, Spain, Turkey
Sanofi
Regeneron Pharmaceuticals

Completed

An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia

Hypercholesterolaemia

Czechia, France, Denmark, Netherlands, Austria, Mexico, Spain, United States, Argentina, Brazil, Bulgaria, Canada, Finland, Hungary, Italy, Lebanon, Norway, Poland, Russian Federation, Slovenia, South Africa, Sweden, Taiwan, Turkey
Tongji Hospital

Recruiting

Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis

Ischemic Stroke | Large-Artery Atherosclerosis (Embolus/Thrombosis)

China
Baylor College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)

Peripheral Arterial Disease

United States

Search clinical trials for: statins, ezetimibe, bempedoic acid, evolocumab, alirocumab, inclisiran

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