Search clinical trials for: systemic non-biological treatments

Total 15028 results

Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Janssen Biotech, Inc.

Completed

Golimumab Safety and Surveillance Program Using the Ingenix NHI Database

Rheumatoid Arthritis | Arthritis, Psoriatic | Ankylosing Spondylitis
Zhejiang Chinese Medical University
Red Cross Hospital, Hangzhou, China; The Third Affiliated hospital of Zhejiang... and other collaborators

Completed

Different Kinds of Acupuncture Treatment for Knee Osteoarthritis

Knee Osteoarthritis

China
Hoffmann-La Roche

Completed

Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs)

Juvenile Idiopathic Arthritis
Shire

Completed

Study of Intrathecal Idursulfase-IT Administered in Conjunction With Elaprase® in Pediatric Patients With Hunter Syndrome and Early Cognitive Impairment (AIM-IT)

Hunter Syndrome

Spain, United States, Canada, United Kingdom, France, Australia, Mexico
Pomeranian Medical University Szczecin

Unknown

Biological Treatment of Amyotrophic Lateral Sclerosis (NeuStem-ALS)

Amyotrophic Lateral Sclerosis

Poland
Centre Hospitalier Universitaire de Besancon

Recruiting

Interest of Anti-telomerase T CD4 Immune Responses for Predicting the Effectiveness of Immunotherapies Targeting PD1 / PDL1 (ITHER)

Cancer

France
Hoffmann-La Roche

Completed

A Study of Tocilizumab Plus Non-biological DMARD in Patients With Moderate to Severe Rheumatoid Arthritis and an Inadequate Response to Non-biological DMARDs

Rheumatoid Arthritis

Portugal
Northern Orthopaedic Division, Denmark

Completed

Evaluation of MRI Diagnosed Meniscal Lesions

Meniscus Lesion

Denmark
Federation of Italian Cooperative Oncology Groups

Recruiting

Prospective and Multicenter Italian Registry of Locally Advanced-Metastatic Urothelial Carcinoma

Carcinoma, Urothelial

Italy
Istituto Ortopedico Rizzoli

Completed

Observational Retrospective Study on the Clinical and Radiographic Outcomes of the Aseptic Pseudarthrosis Treatment of the Upper Limb

Pseudarthrosis

Italy
Hopital Foch

Completed

Identification of Markers (Klotho-FGF23 Axis) as Determinant in the Evolution of Arterial Stiffness During the First Year of Renal Transplant (KLOTHO)

Renal Transplant

France
Ostergotland County Council, Sweden
Region Jönköping County

Not yet recruiting

Effectiveness of Adjunctive Therapy of Emdogain®FL in Non-surgical Periodontal Treatment

Periodontitis
University Hospital, Montpellier

Recruiting

Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies (CAR-T BANK)

Lymphoma and Acute Lymphoblastic Leukemia

France
Necmettin Erbakan University

Not yet recruiting

Non-surgical Periodontal Treatment in Smokers on SIRT-1, NLRP3 Inflammasome and LncRNAs

Periodontitis, Adult
GlaxoSmithKline

Completed

Safety, Reactogenicity and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Non-typeable Haemophilus Influenzae (NTHI) Vaccine

Respiratory Disorders

Australia
HealthCore-NERI
University of California, San Diego; University of Maryland; University of Alabama... and other collaborators

Terminated

Mixed Incontinence: Medical Or Surgical Approach? (MIMOSA)

Urinary Incontinence

United States
University of Pittsburgh
National Institute of Mental Health (NIMH)

Completed

Using Smartphones to Enhance the Treatment of Childhood Anxiety (Smart-CAT)

Anxiety

United States
Centre Hospitalier Universitaire Dijon

Recruiting

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study (API-AHAI)

Autoimmune Hemolytic Anemia | Venous Thromboembolic Disease | Prolonged Anticoagulation

France
Uppsala University

Completed

Effect of Biological Disease Modifying Anti Rheumatic Drug (bDMARD) Treatment on Spinal Fracture Incidence in Patients With Ankylosing Spondylitis (AS)

Spinal Fractures | Ankylosing Spondylitis
Medical University of Vienna

Completed

Recent and Non United Odontoid Fractures

Odontoid Process
Tampere University Hospital
Regionshospitalet Viborg, Skive; Central Finland Hospital District; Satakunta...

Completed

Non-operative Treatment Versus Volar Locking Plate in Treatment of Distal Radius Fracture in Patients Over 65 Years

Distal Radius Fracture

Sweden, Finland, Denmark
Jaseng Hospital of Korean Medicine

Completed

Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation

Lumbar Disc Herniation | Radiculopathy Lumbar

Korea, Republic of
Uppsala University

Completed

Survival After Surgical Treatment of Axis Fractures in Elderly

Spinal Fractures
Peking University Third Hospital

Recruiting

A Cohort Study of Non-surgical Treatment and Exercise Rehabilitation in Patients With Anterior Cruciate Ligament Rupture

Osteoarthritis, Knee | Anterior Cruciate Ligament Rupture

China
Chang Gung Memorial Hospital

Unknown

Parkinson Disease Before and After Medication and Rehabilitation Treatment

Parkinson Disease
Stanford University

Not yet recruiting

Non-Invasive Pulsed Radiofrequency for the Treatment of Neuropathic Pain

Pain, Nerve
Luzerner Kantonsspital
Arthrex GmbH

Not yet recruiting

Lets Agree to Disagree on Operative vs Nonoperative Treatment for Distal Radius Fractures in the Elderly (LADON Radius) (LADON radius)

Radius Fracture Distal
Kolding Sygehus
Odense University Hospital; Karolinska University Hospital; Zealand University... and other collaborators

Recruiting

Scandinavian Humeral Diaphyseal Fracture Trial (SHAFT)

Fracture Humerus of Shaft

Sweden, Finland, Denmark, Norway
Sahlgrenska University Hospital, Sweden

Active, not recruiting

Acute Achilles Tendon Rupture - Choice of Treatment Based on Ultrasound Findings (DUSTAR)

Rupture | Ultrasonography | Acute Disease | Athletic Injuries | Achilles Tendon Rupture

Sweden
Unity Health Toronto
University of British Columbia; McGill University Health Centre/Research Institute... and other collaborators

Completed

Conservative Treatment Versus Operative Plate Fixation for Acute, Displaced Fractures of the Distal Clavicle

Clavicle Fracture | Fractures

Canada
Miromatrix Medical Inc.

Completed

MIRODERM H2H DFU Study (H2H-DFU)

Diabetic Foot Ulcer

United States
Dartmouth-Hitchcock Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation (SPORT)

Low Back Pain | Herniated Disc

United States
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study of IBI112 in Chinese Patients With Psoriasis Who Were Previously Treated With Biologics

Psoriasis

China
Federal University of Rio Grande do Sul

Completed

Surgical and Non-surgical Treatment of Peri-implantitis (Perio-implants)

Peri-implantitis

Brazil
Luiz Antonio Pugliesi Alves de Lima

Unknown

Surgical Treatment of Periimplantitis in Patients With Risk Factors

Type 2 Diabetes Mellitus | Periodontal Diseases | Peri-Implantitis | Smoking, Cigarette

Brazil
University of Arkansas

Completed

Therapeutic Research in Multiple Myeloma

Multiple Myeloma

United States
Zealand University Hospital
Odense University Hospital; Aarhus University Hospital; Aalborg University Hospital

Recruiting

Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia? (CASTING)

Distal Radius Fracture | Distal Forearm Fracture

Denmark
AO Innovation Translation Center

Recruiting

Registry of Pediatric Orthopedic Trauma and Health Outcomes in Skeletally Immature Children

Long Bone Fractures

United States, Canada, Australia, Ghana, Chile, China, Germany, India, Pakistan, Venezuela, Spain, Croatia, Greece
AO Clinical Investigation and Publishing Documentation

Active, not recruiting

Pediatric Femur Fracture Registry (PedFemFx)

Femoral Shaft Fracture

United States, Canada, Switzerland, Germany, Austria
Eunice Kennedy Shriver National Institute of Child...
Washington University School of Medicine

Completed

Classification-Directed Treatment of Low Back Pain

Low Back Pain

United States
University Hospital, Grenoble
University Hospital, Marseille

Completed

Anti-ficolin-2 Autoantibodies in Lupus Nephritis (Ficolupus2)

Lupus Erythematosus, Systemic
Cynosure, Inc.

Terminated

Histological Study on Safety and Efficacy of a RF Device Flexible Applicator for Non-Invasive Lipolysis

Lipolysis

United States
Harvard University
Massachusetts General Hospital; American Psychological Foundation

Unknown

A Study of a Smartphone-based Intervention for Suicidal Inpatients

Suicidal Ideation | Suicide, Attempted | Hopeless
Ostfold Hospital Trust

Recruiting

Use of Weightbearing Radiographs to Determine Treatment of bi- and Trimalleolar Ankle Fractures

Ankle Fracture, Trimalleolar | Ankle Fracture, Bimalleolar

Norway
Dartmouth-Hitchcock Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaborators

Completed

Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis

Low Back Pain | Spinal Stenosis

United States
Biologics & Biosimilars Collective Intelligence...
Merck Sharp & Dohme LLC; Pfizer; AbbVie; University of Pittsburgh; Boehringer Ingelheim and other collaborators

Completed

Incidence of Hospitalizations for Serious Infections in Patients Receiving Biologic Anti-Inflammatories for Rheumatologic, Psoriatic, and Gastrointestinal Conditions: A Descriptive Analysis

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis | Inflammatory Bowel Disease | Ankylosing Spondylitis
Aristotle University Of Thessaloniki
University Hospital of Crete; University Hospital of Patras; Pulmonary Clinic... and other collaborators

Recruiting

BenRalizumab Effect on Airway Remodeling in Severe asTHma (BREATH)

Airway Remodeling | Asthma; Eosinophilic

Greece
Cairo University

Recruiting

Effect of Extraction Vs Non-extraction Orthodontic Treatment on Vertical Facial Dimension

Malocclusion | Crowding, Tooth | Long Face Syndrome

Egypt

Search clinical trials for: systemic non-biological treatments

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