Search clinical trials for: tissue plasminogen activator, tPA

Total 259 results

University of Calgary

Unknown

Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid Hemorrhage

Intraventricular Hemorrhage | Aneurysmal Subarachnoid Hemorrhage

Canada
Boehringer Ingelheim

Completed

Full Dose Tenecteplase (TNK-tPA) Together With Heparin Sodium, Full Dose Tenecteplase With Enoxaparin, Half Dose Tenecteplase Together With Abciximab and Heparin Sodium in Patients With Acute Myocardial Infarction (AMI) (ASSENT 3)

Myocardial Infarction
Mitsubishi Tanabe Pharma Corporation
Kyowa Kirin Co., Ltd.

Completed

Post-marketing Clinical Study of Alteplase for Acute Ischemic Stroke （Japan Alteplase Clinical Trial Ⅱ：J-ACT Ⅱ）

Stroke

Japan
Weill Medical College of Cornell University

Completed

Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein Occlusion

Central Retinal Vein Occlusion

United States
Rush University Medical Center

Withdrawn

Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage

Subarachnoid Hemorrhage | Cerebral Vasospasm | Cerebral Aneurysm | Hydrocephalus

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Application of tPA in Suprachoroidal and Subretinal Hemorrhage

Ocular Trauma

China
Hamilton Health Sciences Corporation

Recruiting

Use of Tissue Plasminogen Activator in the Clearance of Chronic Subdural Hematomas

Hematoma, Subdural | Fibrinolytic; Hemorrhage

Canada
Mashhad University of Medical Sciences

Terminated

Evaluation of the Role of Intravitreal Tissue Plasminogen Activator in Treatment of Refractory Diabetic Macular Edema

Diabetic Macular Edema

Iran, Islamic Republic of
Boehringer Ingelheim

Completed

Temporal Trends of Thrombolysis Treatment in Chinese Acute Ischemic Stroke (AIS) Patients From 2007-2017: Analysis of China National Stroke Registry (CNSR) I, II, and III; CTP-Draft Review Performed;

Stroke

China
Daniel Hanley
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,... and other collaborators

Completed

Minimally Invasive Surgery and rtPA for Intracerebral Hemorrhage Evacuation (MISTIE)

Intracerebral Hemorrhage

United States, Germany, United Kingdom, Canada
University of Manitoba
Hoffmann-La Roche

Terminated

Alteplase for Blood Flow Restoration in Hemodialysis Catheters

Thrombosis

Canada
Tasly Biopharmaceuticals Co., Ltd.

Completed

A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism (ERUPTE)

Acute Pulmonary Embolism

China
Kafrelsheikh University

Recruiting

Predictors of Post-alteplase Hemorrhagic Transformation of Brain Infarction

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
Second Affiliated Hospital, School of Medicine,...
Shaoxing People's Hospital; Huizhou Municipal Central Hospital; The Second Affiliated... and other collaborators

Recruiting

24 Hours Treatment With Alteplase in Patients With Ischemic Stroke

Stroke

China
Boehringer Ingelheim

Terminated

Protocol for Post Marketing Surveillance of Actilyse Vial

Stroke
Mitsubishi Tanabe Pharma Corporation
Kyowa Hakko Kogyo Co., Ltd.

Completed

Japan Alteplase Clinical Trial (J-ACT): Efficacy and Safety Study of Tissue Plasminogen Activator (Alteplase) for Ischemic Stroke

Brain Ischemia | Cerebral Infarction

Japan
O'Brien, Jeana D., MD, FACP, FCCP
Genentech, Inc.; Texas A&M University; Scott and White Hospital & Clinic; Scott...

Unknown

Alteplase for Treatment of Empyema and Complicated Parapneumonic Effusion

Pleural Effusion | Empyema

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

ALteplase in Patients With LOW NIHSS and Specified Disabling Deficits (ALLOW)

Thrombosis

China
Boehringer Ingelheim

Completed

Safety and Efficacy of Alteplase When Administered in Chinese Patients With Acute Ischemic Hemispheric Stroke Where Thrombolysis is Initiated Between 3 and 4.5 Hours After Stroke Onset

Stroke

China
Boehringer Ingelheim

Completed

Safe Implementation of Thrombolysis in Stroke - Monitoring Study

Stroke
Assistance Publique - Hôpitaux de Paris
Canadian Institutes of Health Research (CIHR); Boehringer Ingelheim; Johannes... and other collaborators

Recruiting

Pulmonary Embolism International THrOmbolysis Study-3 (PEITHO-3)

Pulmonary Embolism

Netherlands, Spain, Belgium, Slovenia, France, Portugal, Austria, Canada, Poland, Switzerland, Germany, Italy, Romania, Serbia
The First Affiliated Hospital of Zhengzhou University
Techpool Bio-Pharma Co., Ltd.

Recruiting

Treatment of Acute Ischemic StroKe With Intravenous UroKinase Real-world Research: a Multicenter, Prospective Study

Acute Ischemic Stroke

China
Assiut University

Completed

Intracranial Collaterals in Acute Stroke and Clinical Outcome

Collateral Circulation, Any Site

Egypt
Rabin Medical Center

Terminated

Thrombolysis in Ischemic Spinal Cord Stroke

Motor Weakness in Two or Four Limbs | Damage in the Anterior Spinal Artery (ASA) | Temperature and Superficial Sensation | Urinary Retention or Bowel Disorder

Israel
Kafrelsheikh University

Completed

Predictors of AIS Unfavorable Outcomes

Ischemic Stroke | Alteplase Adverse Reaction

Egypt
General Hospital of Shenyang Military Region

Withdrawn

Intravenous Thrombolysis Registry for Acute Ischemic Stroke in China

Ischemic Stroke

China
University Hospital Tuebingen

Recruiting

Early Reperfusion Therapy With Intravenous Alteplase for Recovery of VISION in Acute Central Retinal Artery Occlusion (REVISION)

Central Retinal Artery Occlusion

Germany
University of Louisville
Genentech, Inc.

Terminated

Safety and Efficacy of Tissue Plasminogen Activator (tPA) in Neonates and Infants

Thrombosis

United States
Richard Chang, M.D.
National Institutes of Health Clinical Center (CC)

Completed

Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins

Acute Deep Venous Thrombosis of the Lower Extremity

United States
Boehringer Ingelheim

Completed

An International Observational Study of the Safety and Efficacy of Thrombolysis in Stroke

Stroke
Assiut University

Not yet recruiting

The Prevalence and Associated Factors of Early Deterioration After Successful Recanalization in Acute Ischemic Stroke

Acute Stroke
Boehringer Ingelheim

Completed

SITS-IVT in Patients >80 Years Study (SITS_ELDERLY)

Ischaemic Stroke

Sweden
Melbourne Health
Boehringer Ingelheim

Completed

Echoplanar Imaging Thrombolysis Evaluation Trial (EPITHET)

Stroke

Australia, New Zealand, Belgium, United Kingdom
The Hospital for Sick Children

Terminated

Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective Study

Intra-abdominal Abscess

Canada
Kaiser Permanente
Genentech, Inc.

Completed

Alteplase for Percutaneous Treatment of Loculated Abdominopelvic Abscesses

Abdominal Abscess | Pelvic Abscess

United States
Genentech, Inc.

Completed

Cathflo Activase Pediatric Study

Dysfunctional Central Venous Access Devices (CVADS)
Nova Scotia Health Authority

Unknown

Intensive Versus Standard Hemodialysis CVC Dysfunction Protocol

Chronic Renal Insufficiency

Canada
Aarhus University Hospital
TRYG Foundation; Danish National Research Foundation; Aase and Ejnar Danielsens...

Completed

New Acute Treatment for Stroke - The Effect of Remote PERconditioning

Acute Stroke

Denmark
Boehringer Ingelheim

Completed

A Study in Chinese Patients to Compare How Tenecteplase and Alteplase Given After a Stroke Improve Recovering of Physical Activity (ORIGINAL)

Stroke

China
Boehringer Ingelheim

Terminated

A Study of Pre-hospital Treatment of Acute Myocardial Infarction Based on Diagnosis by Interpretation of Remotely Acquired ECG and Thrombolysis With Accelerated Alteplase ( Actilyse®) (PHARAOH)

Myocardial Infarction
NHS Greater Glasgow and Clyde
National Institute for Health Research, United Kingdom; University of Glasgow

Completed

A Trial of Low-dose Adjunctive alTeplase During prIMary PCI (T-TIME)

Myocardial Infarction

United Kingdom
University of Cape Town
Population Health Research Institute; Walter Sisulu University

Unknown

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion (IMPI-2)

Pericardial Effusion

South Africa
Lee Schwamm
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,...

Completed

A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients (MR WITNESS)

Acute Stroke

United States
Boehringer Ingelheim

Completed

Efficacy and Safety of Actilyse 2 mg/ 2 ml in Comparison to Saline Solution in Patients With Central Venous Access Device Occlusion

Vascular Access Devices | Catheter Obstruction

Russian Federation
Vastra Gotaland Region

Recruiting

Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study (OPTIMAL)

ST-segment Elevation Myocardial Infarction

Sweden
Boston Scientific Corporation
EKOS Corporation

Completed

Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic® Endovascular System (ACCESS PTS)

Deep Vein Thrombosis | Post-thrombotic Syndrome

United States
Wuhan General Hospital of Guangzhou Military Command

Unknown

Outcome of Intravenous Thrombolysis for Stroke Patients in the 3-4.5 Hour Time Window

Stroke
Sichuan Academy of Medical Sciences
Sichuan Provincial People's Hospital

Recruiting

Direct Endovascular Treatment Versus Bridging Treatment In Basilar Artery Occlusive Stroke (BEST-BAO)

Thrombosis | Acute Ischemic Stroke | Basilar Artery Occlusion | Endovascular Treatment | Alteplase

China
Haukeland University Hospital

Terminated

The Norwegian Tenecteplase Stroke Trial 2 (NOR-TEST 2)

Cerebrovascular Disorders | Ischemic Stroke | Stroke, Acute

Norway
Johns Hopkins University
National Institute of Neurological Disorders and Stroke (NINDS); Genentech,... and other collaborators

Completed

Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (MISTIE-III)

Intracerebral Hemorrhage

United States, Australia, Germany, China, Spain, Canada, Israel, Hungary, United Kingdom

Search clinical trials for: tissue plasminogen activator, tPA

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