Search clinical trials for: ziv-aflibercept

Total 8654 results

GCS IHFB Cognacq-Jay
Fondation ARCAD

Active, not recruiting

TWICE-IRI: Optimization of Second-line Therapy With Aflibercept, Irinotecan (Day 1 or Day 1,3), 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study. (TWICE-IRI)

Metastasis | Cancer Colorectal

France
Regeneron Pharmaceuticals

Completed

Study of the Efficacy and Safety of Intravitreal (IVT) Aflibercept for the Improvement of Moderately Severe to Severe Nonproliferative Diabetic Retinopathy (NPDR) (PANORAMA)

Nonproliferative Diabetic Retinopathy

United States, Germany, Hungary, Japan, Puerto Rico, United Kingdom
National Cancer Institute (NCI)

Completed

Aldesleukin With or Without Ziv-Aflibercept in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by Surgery

Metastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Recurrent Melanoma | Stage IIIC Cutaneous Melanoma AJCC v7 | Stage IIIA Cutaneous Melanoma AJCC v7 | Stage IIIB Cutaneous Melanoma AJCC v7

United States
Sanofi
Regeneron Pharmaceuticals; NSABP Foundation Inc

Completed

Aflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based Regimen (VELOUR)

Neoplasm Metastasis | Colorectal Neoplasms

Italy, Austria, Estonia, Spain, South Africa, Belgium, Puerto Rico, United Kingdom, Sweden, United States, Argentina, Australia, Brazil, Chile, Czech Republic, Denmark, France, Germany, Greece, Korea, Republic of, Netherlands, New... and more
Regeneron Pharmaceuticals

Completed

Anti-angiOpoeitin 2 Plus Anti-vascular eNdothelial Growth Factor as a therapY for Neovascular Age Related Macular Degeneration: Evaluation of a fiXed Combination Intravitreal Injection (ONYX)

Neovascular Age-Related Macular Degeneration

United States
Regeneron Pharmaceuticals
Bayer

Completed

Anti-vasculaR Endothelial Growth Factor plUs Anti-angiopoietin 2 in Fixed comBination therapY: Evaluation for the Treatment of Diabetic Macular Edema (RUBY)

Diabetic Macular Edema

United States
Tennessee Retina
Regeneron Pharmaceuticals

Unknown

Two-week Retreatment Interval Study for Treated Age-related Macular Degeneration Refractory to Monthly Aflibercept (TRISTAR)

Neovascular Age-related Macular Degeneration

United States
Oxurion

Completed

A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Diabetes Mellitus | Diabetic Retinopathy | Diabetic Macular Edema

United States, France, United Kingdom, Spain, Germany, Italy, Slovakia, Czechia
John Kitchens, MD

Unknown

Treatment for Presumed Ocular Histoplasmosis (HANDLE)

Ocular Histoplasmosis

United States
Singapore National Eye Centre
Bayer

Completed

An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy

Age Related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Singapore
Poitiers University Hospital

Active, not recruiting

Real Life Study in Myopic Neovascularization (VIC)

Myopic Choroidal Neovascularisation

France
Hospices Civils de Lyon

Completed

Study Evaluating the Efficacy of Aflibercept for the Treatment of NVCI in Young Patients (INTUITION)

Idiopathic Choroidal Neovascularization

France
National Cancer Institute (NCI)

Completed

Sapanisertib and Ziv-Aflibercept in Treating Patients With Recurrent Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Ovarian Carcinoma | Pancreatic Neuroendocrine Tumor | Unresectable Solid Neoplasm | Fibrolamellar Carcinoma

United States
Fondation Ophtalmologique Adolphe de Rothschild

Completed

Assessment of Visual Acuity in Patients With Polypoidal Choroidal Vasculopathy and Aflibercept Treatment (PCV)

Polypoidal Choroidal Vasculopathy

France
GERCOR - Multidisciplinary Oncology Cooperative...
Sanofi

Completed

OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer (VELVET)

Unresectable Metastatic Colorectal Cancer

France
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Treatment for CI-DME in Eyes With Very Good VA Study (Protocol V)

Diabetic Macular Edema

United States, Canada
Kamal Kishore, MD

Unknown

Intravitreal Aflibercept Injection for Symptomatic Macular Edema From Retinal Artery Macroaneurysms

Macular Edema | Retinal Artery Macroaneurysm

United States
Manhattan Eye, Ear & Throat Hospital
Northwell Health

Withdrawn

Intravitreal Aflibercept Injections In The Treatment Of Pattern Dystrophy (AVA)

Pattern Dystrophy of Macula

United States
Dana-Farber Cancer Institute

Completed

FOLFOX +/- Ziv-Aflibercept for Esophageal and Gastric Cancer

Gastric Cancer | Esophageal Cancer

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of IBI302 in Subjects With nAMD

Neovascular Age-related Macular Degeneration

China
Wake Forest University Health Sciences

Terminated

Vascular Endothelial Growth Factor (VEGF) Levels in Retinal Vein Occlusion (RVO) During Anti-VEGF Treatment

Retinal Vein Occlusion

United States
Stanford University
Regeneron Pharmaceuticals

Withdrawn

A Pharmacokinetic stuDy of intRavitreal Aflibercept Injection in Vitrectomized and Non-vitrectomized Eyes With Diabetic Macular Edema (DRAW-2)

Diabetic Macular Edema

United States
Advanced Eye Research Associates

Active, not recruiting

Assessment of Biomarker Profile in Diabetic Macular Edema With Intravitreal Aflibercept Injection

Diabetic Macular Edema

United States
Rajavithi Hospital

Completed

Intravitreal Aflibercept for Treatment of Polypoidal Choroidal Vasculopathy (PCV)

Symtomatic Macular Polypoidal Choroidal Vasculopathy

Thailand
Taipei Veterans General Hospital, Taiwan
National Taiwan University Hospital; Chang Gung Memorial Hospital; Kaohsiung...

Completed

Efficacy and Safety of Aflibercept as Mono-therapy in Treat and Extend Regimen for DME Patients in Taiwan

Center-involved Diabetic Macular Edema
Barcelona Macula Foundation
Bayer; TFS Trial Form Support

Completed

Study to Evaluate Efficacy of Aflibercept in Neovascular Age-related Macular Degeneration Patients Non Responders to Anti-Vascular Endothelial Growth Factor (MACBETH)

Wet Macular Degeneration

Spain
Samsung Medical Center
Bayer; Seoul National University Bundang Hospital; Kim's Eye Hospital

Completed

Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy

Polypoidal Choroidal Vasculopathy Without Active Polyp

Korea, Republic of
MidAtlantic Retina
Regeneron Pharmaceuticals

Completed

Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration (ATLAS)

Age-Related Macular Degeneration | Macular Degeneration

United States
Retina Research Institute, LLC
Valley Retina Institute

Unknown

Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results

Age Related Macular Degeneration

United States
Maisonneuve-Rosemont Hospital
Bayer

Unknown

Effect of Aflibercept (Eylea®) in the Management of Bevacizumab (Avastin®) Resistant Diabetic Macular Edema (Eylea)

Diabetic Macular Edema

Canada
Sanofi
Regeneron Pharmaceuticals

Completed

A Study to Evaluate the Effects of Aflibercept on QTc Interval in Cancer Patients (QUTIE)

Cancer

United States, Romania, Germany, Italy, Turkey, Belgium, Denmark
Larkin Community Hospital

Completed

Role of Intravitreal Aflibercept Injection for the Treatment of Radiation Maculopathy

Adverse Effect of Radiation Therapy
Rishi Singh
Regeneron Pharmaceuticals

Completed

Treatment of Diabetic Macular Edema With Aflibercept in Subjects Previously Treated With Ranibizumab or Bevacizumab (SwapTwo)

Diabetic Retinopathy | Macular Edema

United States
Southeast Clinical Research Associates, LLC
Regeneron Pharmaceuticals

Withdrawn

Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab

Diabetic Macular Edema

United States
Bayer
Regeneron Pharmaceuticals

Active, not recruiting

Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye (PULSAR)

Neovascular Age-Related Macular Degeneration

United States, Spain, Korea, Republic of, Czechia, Japan, Singapore, China, Serbia, Lithuania, Taiwan, Australia, Estonia, Austria, Israel, France, Italy, Switzerland, Slovakia, Ukraine, Bulgaria, Portugal, Latvia, Canada, Hungary, Arge... and more
Unity Health Toronto

Recruiting

Cytokine and Visual Outcome Variations in Eyes Receiving Aflibercept (COVARIANT)

Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Age Related Macular Degeneration

Canada
Kim's Eye Hospital

Completed

Outcomes of Tolerating Subretinal Fluid in Type 1 MNV and PCV

Age-Related Macular Degeneration | Choroidal Neovascularization | Polypoidal Choroidal Vasculopathy

Korea, Republic of
Bayer

Completed

Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice

Wet Age-related Macular Degeneration

India
Greater Houston Retina Research
The Cleveland Clinic; Regeneron Pharmaceuticals

Completed

Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement

Diabetic Retinopathy

United States
University of Alexandria

Completed

One Year Results of Switching to Aflibercept for Persistent Diabetic Macular Edema Resistant to Bevacizumab

Diabetic Macular Edema
Hadassah Medical Organization
Bayer

Unknown

Aflibercept (EYLEA)as Secondary or Third Line Treatment for Neovascular Age-related Macular Degeneration.

Neovascular Age-related Macular Degeneration

Israel
Sanofi
Regeneron Pharmaceuticals

Completed

A Study of Aflibercept Versus Placebo in Patients With Second-Line Docetaxel for Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (VITAL)

Carcinoma | Non Small Cell Lung

United States, France, Canada, Brazil, Poland, Romania, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Sweden, Bulgaria, Estonia, India, Malaysia, Singapore, Taiwan, Czech Republic, Argentina, Finland, Hungary, Korea... and more
Singapore National Eye Centre
National University Hospital, Singapore; Tan Tock Seng Hospital

Active, not recruiting

Comparing Intravitreal Aflibercept Monotherapy vs Aflibercept Combined With Reduced Fluence PDT in PCV Treatment

Polypoidal Choroidal Vasculopathy

Singapore
Jaeb Center for Health Research

Completed

DRCR.Net Aflibercept vs. Bevacizumab + Deferred Aflibercept for the Treatment of CI-DME (DRCR AC)

Diabetic Macular Edema

United States
Bayer

Completed

Special Drug Use Investigation of EYLEA for Diabetic Macular Edema

Macular Edema

Japan
University of Rochester

Withdrawn

Evaluation of the Retina in Patients With Non-proliferative Diabetic Retinopathy After Aflibercept Injection in the Eye (PRAVA)

Retinopathy, Diabetic

United States
Bayer
Regeneron Pharmaceuticals

Completed

The Impact of Baseline Visual Acuity on the Treatment Outcomes in Patients Treated With AflIbercept in Real-life Clinical Setting (INSIGHT)

Wet Macular Degeneration

Sweden
Vista Klinik
Bayer

Completed

Intravitreal Aflibercept in Neovascular AMD With Limited Response to Ranibizumab

Neovascular Age-related Macular Degeneration
Retina Research Institute, LLC

Completed

Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome

Choroidal Neovascularization | Presumed Ocular Histoplasmosis

United States
Regeneron Pharmaceuticals

Completed

Study to Assess Best Corrected Visual Acuity (BCVA) in Patients With Neovascular Age-Related Macular Degeneration (AMD) Who Are Administered VEGF Trap-Eye (Intravitreal Aflibercept Injection) (RE-VIEW)

Age - Related Macular Degeneration (AMD)

United States

Search clinical trials for: ziv-aflibercept

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