Latest Trials

Total 342 results

Institut National de la Santé Et de la Recherche...
UNITAID

Recruiting

Validation of a Tuberculosis Treatment Decision Algorithm in HIV-infected Children (TB-Speed HIV)

HIV | Tuberculosis

Côte D'Ivoire, Mozambique, Uganda, Zambia
Novartis Pharmaceuticals

Recruiting

Platform Study to Evaluate the Efficacy and Safety of Anti-malarial Agents in Patients With Uncomplicated Plasmodium Falciparum Malaria (PLATINUM)

Uncomplicated Plasmodium Falciparum Malaria

Côte D'Ivoire, Kenya, Ghana, Uganda
ANRS, Emerging Infectious Diseases

Completed

First-Line Treatment for HIV-2 (FIT-2)

HIV-2 Infection

Côte D'Ivoire, Burkina Faso, Senegal, Togo
ANRS, Emerging Infectious Diseases

Unknown

Third Line Antiretroviral Treatment Optimization in Sub-Saharan Africa (THILAO)

HIV Infection

Burkina Faso, Côte D'Ivoire, Mali, Senegal
Medicines Development for Global Health

Recruiting

Safety of a Single Dose of Moxidectin Compared With Ivermectin in Individuals Living in Onchocerciasis Endemic Areas and in Individuals Living in Onchocerciasis Endemic Areas With High Levels of Lymphatic Filariasis Co-endemicity Receiving Concomitant Albendazole

Onchocerciasis

Côte D'Ivoire, Congo, The Democratic Republic of the
Jennifer Keiser
Lao Tropical and Public Health Institute; Centre Suisse de Recherches Scientifiques... and other collaborators

Completed

Efficacy and Safety of IVM/ALB Co-administration

Trichuriasis

Côte D'Ivoire, Tanzania, Lao People's Democratic Republic
Institut de Recherche pour le Developpement
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Completed

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP2 Passive Case Detection (DiTECT-WP2)

Trypanosoma Brucei Gambiense; Infection | Sleeping Sickness; West African | African Trypanosomiases | West African; Trypanosomiasis

Congo, The Democratic Republic of the, Côte D'Ivoire, Guinea
Swiss Tropical & Public Health Institute
Institute of Tropical Medicine, Belgium; B.P. Koirala Institute of Health Sciences and other collaborators

Completed

Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders (NIDIAGDigest)

Shigellosis | Schistosomiasis | Strongyloidiasis | Dientamoebiasis | Giardiasis | Amoebiasis | Soil-transmitted Helminthiasis | Intestinal Salmonellosis | Campylobacteriosis | Aeromonas Spp. Infections | Cryptosporidium Spp. Infections

Côte D'Ivoire, Indonesia, Mali, Nepal
KU Leuven
University of Yaounde; University of Kinshasa; Yaounde Central Hospital; University... and other collaborators

Completed

Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) Trial (NOAAH)

Blood Pressure

Cameroon, Côte D'Ivoire, Gabon, Nigeria, Senegal
Janssen Vaccines & Prevention B.V.
Institut National de la Santé Et de la Recherche Médicale, France; Centre Muraz and other collaborators

Completed

Safety, Tolerability and Immunogenicity Study of 3 Prime-boost Regimens for Ebola Vaccines Ad26.ZEBOV/MVA-BN-Filo in Healthy Adults, Children and Human Immunodeficiency Virus Positive (HIV+) Adults

Hemorrhagic Fever, Ebola

Kenya, Uganda, Burkina Faso, Côte D'Ivoire
Institut Pasteur
The University of Hong Kong; University of Lausanne; University of Lausanne Hospitals and other collaborators

Terminated

Surveillance of Zika-related Microcephaly in Sub-Saharan Africa and Asia

Microcephaly | Congenital Infection

Sri Lanka, Vietnam, Cameroon, China, Côte D'Ivoire
Institut de Recherche pour le Developpement
Institute of Tropical Medicine, Belgium; Institut National de Recherche Biomédicale... and other collaborators

Completed

Diagnostic Tools for Human African Trypanosomiasis Elimination and Clinical Trials: WP3 Post Elimination Monitoring (DiTECT-HAT-WP3)

Sleeping Sickness | Human African Trypanosomiasis | Trypanosoma Brucei Gambiense; Infection | African Trypanosomiases | West African Sleeping Sickness | Trypanosomiasis; African, Due to Trypanosoma Brucei Gambiense, Gambiense

Congo, The Democratic Republic of the, Côte D'Ivoire, Burkina Faso
ANRS, Emerging Infectious Diseases

Completed

Systematic Empirical vs. Test-guided Anti-TB Treatment Impact in Severely Immunosuppressed HIV-infected Adults Initiating ART With CD4 Cell Counts <100/mm3 (STATIS)

HIV-1 Infection

Vietnam, Cambodia, Côte D'Ivoire, Uganda
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; Institut...

Not yet recruiting

Variants of SARS-CoV-2 Causing COVID-19 in Africa (South-Spike)

COVID-19

Burkina Faso, Chad, Congo, Côte D'Ivoire, Gabon, Mali
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis (INTENSE-TBM)

Tuberculous Meningitis

Côte D'Ivoire, Madagascar, South Africa, Uganda
ANRS, Emerging Infectious Diseases
MSD France

Not yet recruiting

DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection (ELDORADO)

HIV-1-infection

Brazil, Cambodia, Cameroon, Côte D'Ivoire, France, Mozambique
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

Cohort Event Monitoring Study of Pyramax®

Malaria,Falciparum

Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon
ANRS, Emerging Infectious Diseases
Merck Sharp & Dohme LLC; Ministry of Health, Brazil

Completed

Raltegravir Versus Efavirenz in Naive HIV-1-infected Patients Receiving Rifampin for Active Tuberculosis (REFLATE TB2)

Tuberculosis | HIV-1 Infection

France, Vietnam, Brazil, Côte D'Ivoire, Mozambique
Cardiologie et Développement
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Unknown

Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose (CADRE)

Sickle Cell Disease | Sickle Cell Anemia

Cameroon, Congo, The Democratic Republic of the, Côte D'Ivoire, Gabon, Mali, Senegal
Pfizer

Completed

Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa

Malaria, Falciparum

Burkina Faso, Kenya, Mali, Ghana, Côte D'Ivoire
Henry M. Jackson Foundation for the Advancement...
RedHill Biopharma Limited; FHI Clinical, Inc.; Joint Program Executive Office...

Recruiting

PROTECT-APT 1: Early Treatment and Post-Exposure Prophylaxis of COVID-19 (PROTECT-APT 1)

SARS-CoV-2

United States, Côte D'Ivoire, South Africa, Thailand
Institut National de la Santé Et de la Recherche...
UNITAID

Completed

Impact of Systematic Early Tuberculosis Detection Using Xpert MTB/RIF Ultra in Children With Severe Pneumonia in High Tuberculosis Burden Countries (TB-Speed Pneumonia)

Covid19 | Tuberculosis | Severe Pneumonia

Uganda, Cambodia, Cameroon, Côte D'Ivoire, Mozambique, Zambia
French Africa Pediatric Oncology Group

Recruiting

Recommendations for the Treatment of Children With Burkitt's Lymphoma (GFALMB2019)

Burkitt Lymphoma

Burkina Faso, Congo, The Democratic Republic of the, Côte D'Ivoire, Mali, Madagascar, Senegal
French Africa Pediatric Oncology Group

Recruiting

Therapeutic Recommendations for Nephroblastoma (GFANEPHRO20)

Nephroblastoma

Burkina Faso, Congo, The Democratic Republic of the, Côte D'Ivoire, Mali, Senegal, Madagascar
French Africa Pediatric Oncology Group

Recruiting

Therapeutic Recommendations For The Treatment Of Children With A Retinoblastoma (GFARB12019)

Retinoblastoma

Burkina Faso, Congo, The Democratic Republic of the, Côte D'Ivoire, Madagascar, Mali, Senegal
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients

Malaria

Burkina Faso, Congo, The Democratic Republic of the, Kenya, Mali, Mozambique, Philippines, Côte D'Ivoire, Gabon
Elizabeth Glaser Pediatric AIDS Foundation

Completed

TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI) (TIPPI)

Tuberculosis | Pediatric

Cameroon, Congo, The Democratic Republic of the, Côte D'Ivoire, India, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe
Hospital Universitario 12 de Octubre
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Active, not recruiting

Empirical Treatment Against Cytomegalovirus and Tuberculosis in HIV-infected Infants With Severe Pneumonia (EMPIRICAL)

Pneumonia | HIV/AIDS | Tuberculosis | Cytomegalovirus Infections

Zimbabwe, France, Côte D'Ivoire, Italy, Malawi, Mozambique, Netherlands, Spain, Uganda, United Kingdom, Zambia
Centre Georges Francois Leclerc

Recruiting

Impact of Non-magnetic Screen Respiratory Self-guidance During MRI-guided Radiotherapy Sessions for Mobile Lesions (RespEcran)

Patient With Radiotherapy (Linac MRI) | Mobile Cancerous Lesion

France
ADDMEDICA SASA

Recruiting

SIKAMIC (SIklos on Kidney Function and AlbuMInuria Clinical Trial) (SIKAMIC)

Sickle Cell Disease

France, Côte D'Ivoire, Guadeloupe, Mali, Martinique, Senegal
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP)

Recruiting

Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria (KALUMI)

Uncomplicated Plasmodium Falciparum Malaria

Burkina Faso, Mali, Gabon, Congo, The Democratic Republic of the, Côte D'Ivoire
Centre Georges Francois Leclerc

Recruiting

Functional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Radical Surgery for Breast Cancer. (BREAST)

Breast Cancer

France
University of Burgundy

Completed

Effect of Stabilization Shoes on Balance in Elderly (BALAGE)

Elderly

France
Centre Georges Francois Leclerc

Recruiting

Influence of Food Preferences on the Occurrence of Undernutrition in Treated Patients for Bronchopulmonary Carcinoma Non-small Cell Stage IV (ONCOGOU)

Non-small Cell Bronchopulmonary Carcinoma at Stage IV and Benefiting From First-line Treatment According to Current French Recommendations

France
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Novartis Pharmaceuticals
Wellcome Trust; European and Developing Countries Clinical Trials Partnership...

Recruiting

To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria

Severe Malaria

Burkina Faso, India, Rwanda, Congo, The Democratic Republic of the, Gabon, Nigeria, Côte D'Ivoire, Kenya, Uganda
VitalTracer Ltd.
St. Justine's Hospital

Not yet recruiting

Comparison of Continuous Non-invasive All Vital Signs Monitoring Devices With Invasive Gold Standard for Children (VT)

Hypertension | Blood Pressure | Children | Intensive Care Unit | Oxygen Saturation | Vital Signs | Neonatal

Canada
Institut Paoli-Calmettes

Recruiting

Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis (ARCHIMEDE)

Sphincter of Oddi Dysfunction | Biliary Stricture | Obstructive Jaundice

France
Centre Hospitalier Henri Duffaut - Avignon

Recruiting

Post-emergency Management of Patients With Transient Ischemic Attack

Transient Ischemic Attack

France
Centre Hospitalier Henri Duffaut - Avignon

Recruiting

Evaluation of Advanced Practice Nurse's Management of Patients With Chronic Myeloid Leukemia (IPA-LMC)

Chronic Myelogenous Leukemia - Chronic Phase

France
Centre Hospitalier Henri Duffaut - Avignon

Recruiting

Assessment of Fatigue in Psoriatic Arthritis and Cutaneous Psoriasis Patients (RPso-Fatigue)

Psoriasis | Psoriatic Arthritis

France
French Africa Pediatric Oncology Group
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Hospital Based Registry of Childhood Cancer in Pediatric Oncology Units in French Speaking Africa (RFAOP)

Pediatric Cancer

Burkina Faso, Cameroon, Congo, The Democratic Republic of the, Côte D'Ivoire, France, Gabon, Madagascar, Mali, Mauritania, Niger, Senegal, Togo
Orthofix s.r.l.

Not yet recruiting

Study to Assess the Pain, Satisfaction, and Quality of Life of Patients With FITBONE® Lengthening Nail (FitForFrance)

Leg Length Inequality

France
Cardiologie et Développement
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa (FEVRIER)

Heart Failure | Stroke | Syncope | Acute Coronary Syndrome | Deep Vein Thrombosis | Pericarditis | Endocarditis | Pulmonary Embolism | Conduction Abnormalities | Rhythm; Abnormal | Other Cardiovascular Conditions

Benin, Burkina Faso, Burundi, Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon, Guinea, Mozambique, Niger, Senegal, Sudan
Centre Hospitalier Universitaire de Nice

Withdrawn

Experimentation of a Personalized Physical Self-education Program at Home: Feasibility Study (PROSOL TELEKINECT) (TELEKINECT)

Neuromuscular Diseases | Neurodegenerative Diseases

Italy, France
University of Bern
University of Zurich; University of Bristol; ETH Zurich; University of KwaZulu

Recruiting

HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen (DTG-Resist)

Hiv

Mexico, Malawi, Argentina, Brazil, Burkina Faso, Cambodia, Cameroon, Congo, Côte D'Ivoire, Kenya, Rwanda, Tanzania, Thailand, Uganda, Zambia, Zimbabwe
Hopital Foch

Recruiting

Impact of NOL Index Intraoperative Guided Remifentanil Analgesia (Eu-MultiNOL)

Abdominal Surgery

France
Institut du Cancer de Montpellier - Val d'Aurelle

Active, not recruiting

Safety, Tolerability and Efficacy of Regorafenib in Combination With FOLFIRINOX in Patients With Colorectal Cancer (FOLFIRINOX-R)

Metastatic Colorectal Cancer

France
University of Oxford

Completed

Chloroquine/ Hydroxychloroquine Prevention of Coronavirus Disease (COVID-19) in the Healthcare Setting (COPCOV)

Coronavirus | COVID19 | Acute Respiratory Illnesses

United Kingdom, Zambia, Thailand, Benin, Côte D'Ivoire, Indonesia, Kenya, Mali, Nepal, Pakistan
Population Health Research Institute

Recruiting

Reducing Mortality in Adults With Advanced HIV Disease (REVIVE) (REVIVE)

HIV Disease Progression

Nigeria, Uganda, South Africa, Botswana, Ghana, Sierra Leone, Congo, Côte D'Ivoire, Ethiopia, Malawi, Mozambique, Rwanda, Tanzania, Zambia

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