Latest Trials

Total 69 results

Baylor College of Medicine

Completed

Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon
Prof. Ayola Akim ADEGNIKA

Recruiting

Seroepidemiological Investigation of Coronavirus 2019 (COVID-19) Infection in Gabon (Sero-CoV)

Laboratory Confirmed SARS-CoV-2 Infection Without Symptoms

Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
Centre de Recherche Médicale de Lambaréné
Medical University of Vienna; University Hospital Tuebingen; Bernhard Nocht Institute...

Completed

Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon

Households | Scabies

Gabon
GlaxoSmithKline

Completed

Double-blind Study of Safety and Immunogenicity of Two Candidate Malaria Vaccines in Gabonese Children

Malaria

Gabon
Zentopharm GmbH
Centro de Investigação em Saúde de Manhiça; Albert Schweitzer Hospital

Unknown

Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria

Malaria

Gabon
African Malaria Network Trust

Unknown

Safety and Immunogenicity of 30 and 100 µg of GMZ2 in Gabonese Children Aged 1-5 Years

Malaria

Gabon
Centre de Recherche Médicale de Lambaréné

Completed

Evaluation of the VOT Among Tuberculosis Patients From Lambaréné (dotsapp)

Tuberculosis

Gabon
Baylor College of Medicine
George Washington University; Amsterdam Institute for Global Health and Development and other collaborators

Completed

Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese Adults

Hookworm Infection | Hookworm Disease

Gabon
Centre de Recherche Médicale de Lambaréné

Completed

Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection (SACT)

Schistosomiasis Haematobia

Gabon
Baylor College of Medicine

Completed

Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese Children

Hookworm Infection | Hookworm Disease

Gabon
Sanaria Inc.
Centre de Recherche Médicale de Lambaréné; Institute of Tropical Medicine,...

Completed

Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge

Malaria | Plasmodium Falciparum Malaria

Gabon
African Malaria Network Trust

Unknown

Safety of Recombinant Hybrid GMZ 2 [GLURP + MSP 3] Blood Stage Malaria Vaccine

Malaria

Gabon
Centre de Recherche Médicale de Lambaréné
Universität Tübingen

Recruiting

Schistosomiasis Diagnosis Using a CAA Antigen Test (FreebiLyGAB)

Pregnancy | Drug Reaction | Diagnostic | Schistosomiasis Hematobium

Gabon
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Hospital Tuebingen; Albert Schweitzer Hospital

Completed

Prediction and Pathogenesis of the Immune Reconstitution Inflammatory Syndrome (IRIS)

Opportunistic Infections | Immune Reconstitution Inflammatory Syndrome

Gabon
Albert Schweitzer Hospital
Bill and Melinda Gates Foundation

Terminated

Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children

Malaria

Gabon
Albert Schweitzer Hospital

Completed

Treatment of Malaria in Gabon With Fosmidomycin-Clindamycin

Malaria

Gabon
Albert Schweitzer Hospital
Mepha Ltd.

Completed

Efficacy, Safety and Pharmacokinetic of ArtequinTM P. Falciparum Malaria

Malaria

Gabon
Centre de Recherche Médicale de Lambaréné
Leiden University Medical Center; European and Developing Countries Clinical... and other collaborators

Completed

Important Data on COVID-19 Profile in Africa (AIDCO)

Coronavirus Infection | Africa

Gabon
Medicines for Malaria Venture
European and Developing Countries Clinical Trials Partnership (EDCTP); Severe...

Completed

Phase II Artesunate Study in Severe Malaria

Malaria

Gabon, Malawi
Centre de Recherche Médicale de Lambaréné
Global Health Innovative Technology Fund

Not yet recruiting

Pan-Malaria Transmission-Blocking Vaccine AnAPN1 (PamTBVac)

Malaria

Gabon
Centre de Recherche Médicale de Lambaréné
Leiden University Medical Center

Recruiting

Validation of INSPiRED Innovative Smart Diagnostic Devices for the Detection of Parasites Infections. (INSPiRED-WP3)

Performance | Sensitivity | Specificity | Testing

Gabon
Centre de Recherche Médicale de Lambaréné
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Institute...

Recruiting

Treatment of Tuberculosis Multidrug Resistance Treatment of Tuberculosis Multidrug Resistance (TB-MR)

Multi-drug Resistant Tuberculosis

Gabon
Centre de Recherche Médicale de Lambaréné

Completed

Human Soil Transmitted Helminths (STH) Resistance to Benzimidazole in School Aged Children Living in Gabon (BenziR)

Drug Resistance | Helminths Infection

Gabon
Albert Schweitzer Hospital

Completed

Efficacy of Albendazole to Treat Intestinal Helminths and Its Effect on Gut Microflora

Intestinal Diseases | Helminthiasis

Gabon
Albert Schweitzer Hospital

Completed

Treatment of Non-falciparum Malaria

Acute Non-falciparum Malaria

Gabon
Albert Schweitzer Hospital

Completed

Treatment of Malaria With Quinine Plus Sulfadoxine-Pyrimethamine

Malaria

Gabon
Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon
Barcelona Institute for Global Health
Centro de Investigação em Saúde de Manhiça; Centre de Recherche Médicale de... and other collaborators

Active, not recruiting

Prevalence and Impact of COVID-19 on Maternal and Infant Health in African Populations (MA-CoV)

COVID-19 | SARS-CoV2 Infection

Gabon, Mozambique
Barcelona Institute for Global Health
Medical University of Vienna; Centro de Investigação em Saúde de Manhiça; Centre... and other collaborators

Completed

Improving Maternal heAlth by Reducing Malaria in African HIV Women (MAMAH)

HIV/AIDS | Pregnancy Related | Malaria

Gabon, Mozambique
Centre de Recherche Médicale de Lambaréné
University Hospital Tuebingen; Technical University of Munich

Completed

Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study (HELMVIT)

Vitamin D Deficiency | Immunosuppression

Gabon
Centre de Recherche Médicale de Lambaréné
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon (EBOLAPED)

Ebola Virus Disease

Gabon
Sanaria Inc.
Centre de Recherches Médicales de Lambaréné (CERMEL), German Center for Infection...

Completed

Safety, Tolerability and Protective Efficacy of PfSPZ Vaccine in Gabonese Children

Malaria

Gabon
Albert Schweitzer Hospital
German Research Foundation; Bill and Melinda Gates Foundation; Deutscher Akademischer... and other collaborators

Completed

Reducing the Effects of Malaria in Children by Administering Repeated Preventive Doses

Malaria

Gabon
Sanofi

Completed

A Comparative Safety and Activity Study With Ferroquine Associated With Artesunate Versus Amodiaquine Associated With Artesunate in African Adult Patients With Uncomplicated Malaria

Malaria

Gabon, Kenya
Albert Schweitzer Hospital

Completed

Efficacy of Fosmidomycin-Clindamycin for Treating Malaria in Gabonese Children

Malaria

Gabon
Albert Schweitzer Hospital

Completed

Treatment of Fever Due to Malaria With Ibuprofen

Fever

Gabon
Prof JMA Lange
European and Developing Countries Clinical Trials Partnership (EDCTP)

Terminated

Prevention of Early Mortality by Presumptive Tuberculosis (TB) Treatment (PrOMPT)

HIV Infection | Tuberculosis

Gabon, Mozambique, Uganda
Albert Schweitzer Hospital

Completed

Activity of Mefloquine Against Urinary Schistosomiasis

Urinary Schistosomiasis

Gabon
Albert Schweitzer Hospital
Medical University of Vienna

Completed

Relapses in Plasmodium Ovale and Efficacy of Artemether-lumefantrine for Mixed Species and Non-falciparum Malaria (REPLAMO)

Malaria

Gabon
University Hospital Tuebingen

Completed

Assessing the Effect of Neglected Tropical Diseases on Plasmodium Falciparum Transmission in an Area of Co-endemicity (TRANSMAL)

Malaria Transmission

Gabon, Ghana
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
Foundation for Innovative New Diagnostics, Switzerland
Centre de Recherche Médicale de Lambaréné; Instituto Nacional de Infectologia... and other collaborators

Completed

Validation of Promising Biomarker Assays to Assess Their Diagnostic Performance Characteristics

Acute Febrile Illnesses

Brazil, Gabon, Malawi
Sanofi

Terminated

Study of SAR97276A in the Treatment of Uncomplicated and Severe Malaria in Adults and Children.

Malaria

Benin, Burkina Faso, Gabon, Tanzania
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen

Malaria

Ghana, Tanzania, Gabon
Gynuity Health Projects

Terminated

Mifepristone and Misoprostol Versus Misoprostol Alone for Missed Abortion: A Randomized-controlled Trial

Pregnancy | Missed Abortion

Argentina, Gabon, Mexico, Pakistan
Sanofi

Terminated

Anti-parasitic Activity and Safety Assessment of SAR97276A in Children With Uncomplicated Malaria

Malaria

Benin, Burkina Faso, Gabon, Kenya
Sanofi
Medicines for Malaria Venture

Completed

Study to Investigate the Clinical and Parasiticidal Activity and Pharmacokinetics of Different Doses of Artefenomel and Ferroquine in Patients With Uncomplicated Plasmodium Falciparum Malaria

Plasmodium Falciparum Infection

Benin, Burkina Faso, Gabon, Kenya, Uganda
Hospital Clinic of Barcelona
Centers for Disease Control and Prevention; Ifakara Health Institute; Kenya Medical... and other collaborators

Completed

Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy (MiPPAD)

HIV Infections | Pregnancy | Malaria

Benin, Gabon, Kenya, Mozambique, Tanzania
Novartis Pharmaceuticals
European and Developing Countries Clinical Trials Partnership (EDCTP)

Recruiting

Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria (KALUMI)

Uncomplicated Plasmodium Falciparum Malaria

Burkina Faso, Mali, Gabon

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