Latest Trials

Total 9805 results

Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
medac GmbH
Syneos Health

Recruiting

PK, PD, Safety and Immunogenicity of Spectrila in Adults With Acute B-cell Lymphoblastic Leukaemia

Acute B-Cell Lymphoblastic Leukaemia

Brazil
MARIO ABBUD FILHO

Unknown

Effects of the Use of "de Novo" Everolimus in Renal Tranplant Population

Delayed Function of Renal Transplant

Brazil
Hoffmann-La Roche

Completed

Efficacy and Safety of Peg-Interferon Alpha-2a Plus Ribavirin in Genotype 1 Chronic Hepatitis C Participants Co-Infected With Human Immunodeficiency Virus

Hepatitis C, Chronic

Brazil
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

The Safety of Zidovudine Plus Interferon-Alpha in HIV-Infected Children

HIV Infections

United States, Puerto Rico
Zimmer Biomet

Completed

Post Market Surveillance to Evaluate the Effectiveness the Polaris Deformity Spinal System

Spinal Deformity

United States, Puerto Rico
Idera Pharmaceuticals, Inc.

Completed

Placebo-controlled, Dose-escalation Study of the Safety of IMO-2125 (Immunomodulatory Oligonucleotide) in Hepatitis C-infected Patients

Hepatitis C

United States, Puerto Rico
Westat
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy...

Completed

Evaluating the Response to Two Antiretroviral Medication Regimens in HIV-Infected Pregnant Women, Who Begin Antiretroviral Therapy Between 20 and 36 Weeks of Pregnancy, for the Prevention of Mother-to-Child Transmission

HIV Infections

United States, Puerto Rico, Thailand, Argentina, Brazil, South Africa, Tanzania
Janssen Pharmaceutica

Completed

A Study to Assess the Severity of Psoriasis in Brazilians Participants With Chronic Plaque-type Psoriasis

Psoriasis | Plaque

Brazil
Keryx Biopharmaceuticals
Collaborative Study Group (CSG)

Completed

A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease

End-Stage Renal Disease | Hyperphosphatemia

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Drug Interactions Between Lopinavir/Ritonavir and Oral or Patch Contraceptives in HIV Infected Women

HIV Infections | Pregnancy

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Phase I Safety and Pharmacokinetics Study of Microparticulate Atovaquone (m-Atovaquone; 566C80) in HIV-Infected and Perinatally Exposed Infants and Children

HIV Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
H. Lee Moffitt Cancer Center and Research Institute
Sanofi

Completed

Phase III of RRM1 & ERCC1 Directed Customized Chemotherapy for the Treatment of Patients With NSCLC

Non-Small Cell Lung Cancer

United States, Germany, Puerto Rico
Gilead Sciences

Completed

Dose-Ranging Study of Sofosbuvir in Combination With Pegylated Interferon and Ribavirin in Treatment Naïve GT 1 HCV Patients

Hepatitis C

United States, Puerto Rico
Eurofarma Laboratorios S.A.

Withdrawn

Clinical Study, Multicenter, Randomized With 2 Arms of Pantoprazole + Domperidone and Pantoprazole Isolated at the Gastroesophageal Reflux Disease (PANDA)

Gastroesophageal Reflux Disease

Brazil
Yale University
National Institute on Drug Abuse (NIDA); Albert Einstein College of Medicine; University of Miami and other collaborators

Recruiting

Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support (TCN-PATHS)

Opioid Addiction

United States, Puerto Rico
Takeda

Completed

Safety, Immunogenicity, and Dose Ranging Study of Inactivated Zika Virus Vaccine in Healthy Participants

Flavivirus Infections | Healthy Participants | Virus, Zika | Zika Virus Disease

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults

HIV-1

United States, Puerto Rico
Bristol-Myers Squibb

Completed

A Multiple Ascending Dose Study of Daclatasvir (BMS-790052) in Hepatitis C Virus Genotype 1 Infected Subjects

Chronic Hepatitis C

United States, Puerto Rico
University of Miami
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Columbia University and other collaborators

Completed

Long-term Effects of Highly Active Anti-Retroviral Therapy on HIV-Infected Children

HIV Infections

United States, Puerto Rico
DARA Therapeutics

Completed

Neuropathic Pain in Patients With Cancer

Neuropathic Pain

United States, Puerto Rico
AstraZeneca
Hospital Israelita Albert Einstein

Recruiting

Brazilian Reality of Urinary Bladder Cancers - BRA-BLADDER

Urothelial Carcinoma | Muscle-invasive Bladder Cancer | Non Muscle Invasive Bladder Cancer

Brazil
Janssen-Cilag Ltd.

Completed

Study to Describe the Actual Situation of Hepatitis C Treatment in Brazil (PICTURE)

Hepatitis C Virus

Brazil
Hospital Moinhos de Vento
Boehringer Ingelheim; Ministry of Health, Brazil; Brainomix Limited; iSchemaView...

Recruiting

Randomization to Extend Stroke Intravenous ThromboLysis In Evolving Non-Large Vessel Occlusion With TNK (RESILIENT (EXTEND-IV)

Ischemic Stroke, Acute

Brazil
Bristol-Myers Squibb

Terminated

Study of Abatacept in the Treatment of Hospitalized COVID-19 Participants With Respiratory Compromise

COVID-19 | SARS-CoV-2

Puerto Rico, United States
University of Miami
National Institute on Drug Abuse (NIDA); Oregon Research Institute

Completed

Brief Strategic Family Therapy for Adolescent Drug Abusers (BSFT)

Substance Abuse

United States, Puerto Rico
Eli Lilly and Company

Completed

Pemetrexed Plus Gemcitabine in Metastatic Breast Cancer Patients After Receiving Taxane Therapy

Breast Cancer | Breast Neoplasms

United States, Puerto Rico
Glaxo Wellcome

Completed

A Study of Two Anti-HIV Drug Combinations

HIV Infections

United States, Puerto Rico
Nanoscope Therapeutics Inc.

Completed

Observational Study to Assess the Reliability and Validity of the MLYMT and MLSDT

Retinitis Pigmentosa | Retinal Dystrophy

United States, Puerto Rico
Virionyx Corporation Limited

Terminated

A Trial of PEHRG214 in HIV-Infected Patients

HIV Infections

United States, Puerto Rico
Dana-Farber Cancer Institute
Boston Children's Hospital

Terminated

Treatment of Childhood Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States, Puerto Rico, Canada
AbbVie

Completed

Study to Evaluate the Safety and How the Body Handles a Single Dose of Subcutaneous (SC) and Intravenous (IV) Budigalimab in Adult Participants Living With Human Immunodeficiency Virus (HIV)

Human Immunodeficiency Virus (HIV)

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Safety and Immune Response to Vicriviroc in Combination Regimens in HIV-Infected ART Experienced Children and Adolescents

HIV Infections

United States, Puerto Rico
General Genetics Corporation
Syntactx

Unknown

Pharmacogenomic Testing Of the Elderly To Reduce Morbidity (POETRY)

Genetics of Drug Metabolism

United States, Puerto Rico
Takeda

Completed

Non-interventional Study of Moderate to Severe Inflammatory Bowel Disease in Brazil

Inflammatory Bowel Disease

Brazil
Latin American Cooperative Oncology Group
Astellas Pharma Inc

Terminated

Retrospective Analysis of 68Ga-PSMA-PET in Patients With Prostate Cancer: Experience From Brazil (PET-PSMA)

Prostate Cancer

Brazil
Pfizer
Arvinas Estrogen Receptor, Inc.; Carrick Therapeutics Limited

Recruiting

TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer. (Sub-Study C)

Breast Cancer

United States, Belgium, Puerto Rico
Ache Laboratorios Farmaceuticos S.A.

Unknown

Melatonin 3mg and 5mg Compared to Cognitive Behavioral Therapy for Insomnia (CBT-I) in the Treatment of Insomnia (Morfeu)

Insomnia Disorder

Brazil
Boehringer Ingelheim

No longer available

Expanded Access Program of Nintedanib in Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

Brazil
Butantan Institute
Butantan Foundation

Active, not recruiting

Safety and Immunogenicity of the Butantan Quadrivalent Influenza Vaccine

Influenza, Human

Brazil
Alcon Research

Enrolling by invitation

A Real-World Evidence (RWE) Long-Term Follow-Up Study to Assess Outcomes of Alcon Monofocal Intraocular Lenses

Aphakia

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Evaluating the Safety and Immunogenicity of a Human Parainfluenza Type 3 (HPIV3) Virus Vaccine in Infants and Children

Parainfluenza Virus 3, Human

United States, Puerto Rico
Hospital do Coracao
Bactiguard AB

Completed

Coated Devices to Decrease Infection in the Intensive Care Unit (CRITIC)

Critically Ill

Brazil
PharmaMar

Completed

Multicenter Trial to Treat Patients With Relapsed/Refractory Aggressive Non Hodgkin Lymphoma

Lymphoma | Leukemia

Italy, France, Switzerland, Spain, Peru, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Saquinavir/Ritonavir in Liver-Impaired Patients With HIV Infection.

HIV Infections

Canada, United States, Puerto Rico
University of North Carolina, Chapel Hill
National Institute on Drug Abuse (NIDA); National Institute of Mental Health...

Completed

C2P - Phase III: MPowerment and Community Promise

HIV Infections

United States, Puerto Rico
Lantheus Medical Imaging

Completed

Post-PCI:Cardiac Imaging in Patients With Diabetes to Detect Coronary Artery Blockages Previously Opened by Angioplasty

Diabetes Mellitus, Type 2 | Coronary Restenosis

Puerto Rico, United States
Hepion Pharmaceuticals, Inc.

Completed

A Study of CRV431 Dosed Once Daily in NASH Induced F2 and F3 Subjects (AMBITION)

Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | NAFLD - Nonalcoholic Fatty Liver Disease

United States, Puerto Rico
Eli Lilly and Company

Completed

A Study of LY3023414 in Participants With Advanced Cancer

Non-Hodgkin's Lymphoma | Metastatic Cancer | Malignant Mesothelioma | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Advanced Cancer

United States, Puerto Rico, Italy
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group

Completed

Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults

HIV Infections

United States, Puerto Rico

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