Search clinical trials for: Early symptomatic

Total 11942 results

Gene Solutions
University of Medicine and Pharmacy at Ho Chi Minh City

Recruiting

Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE) (K-ACCELERATE)

Cancer, Breast | Cancer, Lung | Cancer Colon | Cancer, Gastric | Cancer, Liver

Vietnam
Eli Lilly and Company

Not yet recruiting

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease

United States, United Kingdom, Japan
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark
Academisch Medisch Centrum - Universiteit van Amsterdam...
Princess Beatrix Muscle Foundation

Recruiting

Add-on Intravenous Immunoglobulins in Early Myositis (TIMEISMUSCLE)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Inflammatory Myopathy, Idiopathic

Netherlands
MedMira Laboratories Inc.
Public Health Agency of Canada (PHAC)

Recruiting

Evaluation of the Sensitivity, Specificity, and Utility of the Reveal® TP (Syphilis) Antibody POCT

Syphilis | Syphilis Infection | Early Syphilis, Symptomatic

Canada
University of Oxford

Recruiting

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza (AD ASTRA)

Influenza | Influenza, Human

Thailand
Assiut University

Not yet recruiting

Outcomes of Early Referral to Radiofrequency Ablation in Symptomatic Atrial Fibrillation Patients.

Atrial Fibrillation | Radiofrequency Ablation
Eli Lilly and Company

Recruiting

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies

China, Australia, Taiwan, Korea, Republic of, United Kingdom, Argentina
Kolon TissueGene, Inc.

Not yet recruiting

A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis

Degenerative Osteoarthritis
Meshalkin Research Institute of Pathology of Circulation
Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical... and other collaborators

Recruiting

Carotid Revascularization With MicroNet Covered Stent Comparing Early Neurological Outcomes With Distal Versus Proximal EPS (SIBERIA-2)

Patients With Aterosclerotic Carotid Stenosis | Symptomatic Patients (Stenosis > 50%) | Asymptomatic Patients (Stenosis ≥80%)

Russian Federation
University of Oxford

Recruiting

Finding Treatments for COVID-19: A Trial of Antiviral Pharmacodynamics in Early Symptomatic COVID-19 (PLATCOV) (PLATCOV)

COVID-19

Lao People's Democratic Republic, Thailand, Brazil, Pakistan
Cedars-Sinai Medical Center

Recruiting

Terazosin Effect on Cardiac Changes in Early Parkinson's Disease

REM Sleep Behavior Disorder | Pre-motor Parkinson's Disease | Symptomatic Parkinson Disease

United States
Michele Tagliati, MD

Recruiting

Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease (Protocol 53136)

REM Sleep Behavior Disorder | Symptomatic Parkinson Disease | Pre-motor Parkinson Disease

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Randomized Trial Comparing Laparoscopic-assisted Rectosigmoid Resection Versus Laparoscopic Rectosigmoid Resection With Transrectal Specimen Retrieval (LATA)

Symptomatic Recurrent Diverticular Disease | Benign Adenomatous Sigmoidal Polyp, Requiring Surgery | Early Non-transmural Sigmoidtumor

Belgium
Neovasc Inc.

Active, not recruiting

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System (TIARA-I)

Mitral Valve Regurgitation

United States, Canada, Belgium
Clene Nanomedicine

Active, not recruiting

An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS

Amyotrophic Lateral Sclerosis

Australia
Hospital Universitario Reina Sofia de Cordoba
Spanish Society of Family and Community Medicine

Completed

Effectiveness of Early Detection of Atrial Fibrillation (FAMDAP)

Atrial Fibrillation
Anteris Technologies Ltd.

Active, not recruiting

Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study (DurAVR™ EFS)

Aortic Stenosis | Aortic Valve Calcification | Severe Aortic Valve Stenosis | Symptomatic Aortic Stenosis

United States
Notitia Biotechnologies Company
University of South Florida; Rutgers University

Completed

NBT-NM108 as an Early Treatment for Suspected or Confirmed Symptomatic COVID-19 Patients (COVGUT20)

Suspected or Confirmed COVID-19

United States
Eli Lilly and Company

Completed

A Study of Donanemab (LY3002813) Compared With Aducanumab in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 4)

Mild Cognitive Impairment (MCI) | Alzheimer Disease

United States
Cedars-Sinai Medical Center

Enrolling by invitation

Cardiac Changes in Early Parkinson's Disease: A Follow up Study

REM Sleep Behavior Disorder | Symptomatic Parkinson Disease | Pre-motor Parkinson Disease

United States
Eli Lilly and Company

Completed

A Study of LY3002813 in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ)

Alzheimer Disease

United States, Canada
Eli Lilly and Company

Completed

A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease

Alzheimer Disease (AD)

United States, Canada, Japan
Thrombosis Research Institute
Sanofi

Terminated

Early Prophylactic Low-molecular-weight Heparin (LMWH) in Symptomatic COVID-19 Positive Patients (ETHIC)

COVID-19

Australia, Belgium, South Africa
Assiut University
Manchester University NHS Foundation Trust

Unknown

Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease

Coronary Artery Disease | Aortic Valve Disease

Egypt
Avid Radiopharmaceuticals

Completed

Tau Screening Study in Subjects With Early Symptomatic AD

Alzheimer Disease

United States
Avid Radiopharmaceuticals

Completed

Tau Screening Study in Patients With Early Symptomatic AD

Alzheimer Disease

United States, Canada
AstraZeneca

Approved for marketing

An Intermediate Access Protocol for Selumetinib for Treatment of Neurofibromatosis Type 1

NF type1 With Inoperable Plexiform Neurofibromas

United States
University of British Columbia
Huntington Study Group; Huntington Society of Canada

Completed

A Trial of Memantine as Symptomatic Treatment for Early Huntington Disease (MITIGATE-HD)

Huntington Disease

Canada
Aston University
The Dunhill Medical Trust

Completed

Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR) (CEDAR)

Age Related Macular Degeneration

United Kingdom
Janssen Research & Development, LLC

No longer available

A Study of Abiraterone Acetate Plus Prednisone in Asymptomatic or Mildly Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer

Prostate Neoplasms

Brazil
Nanfang Hospital of Southern Medical University

Unknown

Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL

Leukemia, Acute | Leukemia, Lymphoblastic | Leukemia, T Cell

China
Mitralign, Inc.

Unknown

Early Feasibility of the Mitralign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) Also Known as TriAlign™. (SCOUT)

Heart Valve Disease | Tricuspid Valve Insufficiency | Chronic Symptomatic Functional Tricuspid Regurgitation

United States
Lexicon Pharmaceuticals

Recruiting

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy (SONATA-HCM)

Non-obstructive Hypertrophic Cardiomyopathy | Obstructive Cardiomyopathy, Hypertrophic

United States
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH); University of Kansas

Not yet recruiting

Talk With Me Baby to Enhance the Early Home Language Environment (TWMB)

Infant Behavior | Infant Development | Language Development | Language | Language, Child | Speech

United States
St. Jude Children's Research Hospital

Not yet recruiting

Feasibility of Screening for Early Late Effects of Contemporary Therapy in High-Risk Neuroblastoma Survivors

High-risk Neuroblastoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Tricuspid Valve Insufficiency

United States
Peking University People's Hospital

Recruiting

Interactions Between Environmental Exposures and Gut Microbiota in Early Life

Infant Development

China
Qun Zhao

Recruiting

Machine Learning-driven Noninvasive Screening of Transcriptomics Liquid Biopsies for Early Diagnosis of Occult Peritoneal Metastases in Locally Advanced Gastric Cancer

1. Locally Advanced Gastric Cancer (LAGC): The Primary Condition Under Investigation is Locally Advanced Gastric Cancer, Which Refers to Stomach

China
NATALIA LOPERA MUNERA
University Children's Hospital, Zurich; Hospital Pablo Tobón Uribe; Universidad... and other collaborators

Not yet recruiting

Early Resuscitation in Paediatric Sepsis Using Inotropes (ANDES-CHILD)

Sepsis

Argentina, Bolivia, Paraguay
European Institute of Oncology

Not yet recruiting

Intra-SURGerY High-resolution Specimen PET/CT Imager for Margin Assessment in Early-stage Breast Cancer (SURGYPET)

Breast Cancer | Breast-conserving Surgery

Italy
City of Hope Medical Center

Recruiting

Predicting Early Tumor Recurrence in Patients With ESCC

Recurrence | Esophageal Cancer | DNA Methylation

Japan
Xin-Ning Lee

Not yet recruiting

RCT How an Online Escape Room Game Enhances Nurses' Learning Outcomes Regarding ESW Signs.

Early Goal-Directed Therapy
RenJi Hospital

Not yet recruiting

Efficacy and Safety of Rivaroxaban in the Early Postoperative Period for Patients With Bioprosthetic Valves

Anticoagulation
Xiangya Hospital of Central South University

Not yet recruiting

Efficacy and Safety of Early Initiation of Butylphthalide Treatment in Patients With Acute Ischemic Stroke.

Acute Ischemic Stroke
Nantes University Hospital

Not yet recruiting

Pharmaco Mechanical Thrombolysis Associated With Anticoagulation Compared With Anticoagulation in the Acute Phase of Very Symptomatic Proximal Venous Thrombosis of the Lower Limbs. (PMT-DVT)

Iliofemoral Venous Thrombosis
Haukeland University Hospital
University of Bergen; Western Norway University of Applied Sciences

Recruiting

Promoting Mental Health in Young Children - a Dialogue Based Approach in Kindergartens (PRO-DIALOG)

Child Behavior | Child Development

Norway
Azienda Usl di Bologna

Recruiting

Renal Outcomes in the Early Use of Vasopressin in the Treatment of Septic Shock (EVSS)

Septic Shock | Renal Function Replacement

Italy
Zunyi Medical College

Recruiting

A Real-World Study of Pyrrolitinib Maleate Tablets for HER-2-Positive Early or Locally Advanced Breast Cancer After Adjuvant Trastuzumab Therapy

HER-2 Positive Advanced Breast Cancer

China
Zaparackas and Knepper LTD
Northwestern University Feinberg School of Medicine

Not yet recruiting

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

United States

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