Search clinical trials for: GBA1 gene

Total 270774 results

Lawson Health Research Institute
Western University, Canada; London Health Sciences Centre; Weston Brain Institute

Active, not recruiting

Ambroxol as a Treatment for Parkinson's Disease Dementia

Parkinson's Disease Dementia

Canada
University Medical Center Groningen

Recruiting

GRoningen Early-PD Ambroxol Treatment (GREAT)

Parkinson Disease | Parkinson

Netherlands
Shaare Zedek Medical Center

Recruiting

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Healthy | Gaucher Disease, Type 1

Israel
Agyany Pharma LTD

Recruiting

High-Dose Ambroxol in GBA1-Related Parkinson

Parkinson Disease | GBA Gene Mutation

Israel
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2a Clinical Trial of PR001 (LY3884961) in Patients With Parkinson's Disease With at Least One GBA1 Mutation (PROPEL)

Parkinson Disease

United States, Israel
Prevail Therapeutics
Eli Lilly and Company

Recruiting

A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)

Gaucher Disease | Gaucher Disease, Type 1

United States, Spain, Germany
Prevail Therapeutics
Eli Lilly and Company

Active, not recruiting

Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

Gaucher Disease, Type 2

United States, United Kingdom
Bial R&D Investments, S.A.

Recruiting

Efficacy, Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of BIA 28-6156 in GBA-PD (ACTIVATE)

Parkinson's Disease

United States, Spain, France, Italy, Netherlands, United Kingdom, Germany, Canada, Poland, Portugal, Sweden
EyeCool Therapeutics, Inc.

Not yet recruiting

A Prospective Early-Feasibility Study to Evaluate the Safety and Effectiveness of the ETX-4143 2.0 Device.

Eye Pain
Mackay Memorial Hospital

Recruiting

Efficacy of Solifenacin or Mirabegron With Local Estrogen Versus Combination Pharmacotherapy for Overactive Bladder

Urinary Bladder, Overactive | Effect of Drug

Taiwan
Baylor College of Medicine
National Institute of Mental Health (NIMH)

Recruiting

Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant Depression

Healthy | Major Depressive Disorder | Treatment Resistant Depression

United States
The Archer-Daniels-Midland Company
Vedic Lifesciences Pvt. Ltd.

Not yet recruiting

Effect of a Multi-strain Probiotic on Recurrent Vulvovaginal Candidiasis (PROVELIA)

Vulvovaginal Candidiasis
Alexandra Hospital

Not yet recruiting

VR-Guided Mindfulness for ESKD Caregiver Well-Being

Kidney Failure, Chronic
Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus Pred in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Children's Hospital of Fudan University

Recruiting

A Long-term Follow-up Study in Participants Who Received CS-101

Beta-Thalassemia

China
Riphah International University

Recruiting

Effects of Chest Physiotherapy and Lungs Squeezing Technique in Patients With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease

Pakistan
University Hospital Schleswig-Holstein
University of Southern Denmark; Medical School Hamburg

Not yet recruiting

Pneumonitis in Older Lung Cancer Patients After Radiotherapy (POLCAR)

Lung Cancer

Denmark, Germany
Ain Shams University

Recruiting

Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of Cervical Spondylosis Pain

Neck Pain | Cervical Spondylosis

Egypt
Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus DEX in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Yunfeng Cheng
Shanghai Zhongshan Hospital; Shanghai Jinshan Hospital; Macau University of Science... and other collaborators

Recruiting

The Efficacy and Safety of HCQ Plus TPO-RA in ANA Positive ITP

Immune Thrombocytopenia With Positive ANA Antibodies

China, Hong Kong, Macau
Second Affiliated Hospital of Guangzhou Medical...

Not yet recruiting

Stem Cell Derived Exome for Treatment of Diabetic Foot

Diabetic Foot | Stem Cell

China
Shalamar Institute of Health Sciences

Not yet recruiting

Effects of Pediatric Endurance and Limb Strengthening (PEDALS) Program VS Task-Oriented Training (TOT) Improving Gross Motor Function in Children With Cerebral Palsy (PEDALS)

Cerebral Palsy

Pakistan
National Institute of Allergy and Infectious Diseases...

Not yet recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Staphylococcal Infections

United States
Fujian Medical University
First Affiliated Hospital of Fujian Medical University

Not yet recruiting

Estimate the Relationship Between Oral Microbiota and Stroke

Stroke | Microbial Disease

China
Anhui Provincial Hospital
Beijing Pins Medical Co., Ltd

Recruiting

Differences in Brain Network Mechanisms Between STN and GPi Deep Brain Stimulation in the Treatment of Craniocervical Dystonia

Dystonia

China
University Health Network, Toronto
Ontario Shores Centre for Mental Health Sciences

Recruiting

i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial (Ket-CBT)

Suicide | Major Depressive Disorder | Treatment Resistant Depression

Canada
Riphah International University

Recruiting

Effects of Pilate Versus Aerobic Exercises on Dyspnea , Functional Capacity and Anxiety Status in Patients With COPD

COPD Patients

Pakistan
Matthew Grosso, MD

Recruiting

Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty

Postoperative Pain

United States
University of Nebraska
Nevro Corp

Not yet recruiting

SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease

Diabetes Mellitus, Type 2 | Chronic Pain | Peripheral Arterial Disease | Chronic Pain Syndrome | Painful Diabetic Neuropathy | Limb Pain | Spinal Cord Stimulation

United States
Cardiovascular and Interventional Radiological...
Boston Scientific Corporation

Not yet recruiting

BOne Metastases REgistry for Patients Undergoing cryoAbLation With curatIve purpoSe (BOREALIS)

Bone Metastases
Kessler Foundation

Not yet recruiting

A Strength-Based Intervention to Improve Job Interview Skills in Neurodiverse Young Adults

ADHD | Dyslexia | Learning Disabilities
Universiti Sains Malaysia

Not yet recruiting

Compare the Efficacy and Outcome Between Fentanyl and Morphine as Analgo-sedation in Mechanically Ventilated Patients

Effect of Drug

Malaysia
University Hospital, Strasbourg, France

Not yet recruiting

Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders. (SOM-EMO-TND)

Autism Spectrum Disorder (ASD) | Attention Deficit Disorder With or Without Hyperactivity (ADHD)
Amsterdam UMC, location VUmc

Not yet recruiting

Effect of Exercise Type on Muscle Quality in Patients With OA, SARC and RA: an Explorative Study (C4M)

Osteoarthritis | Rheumatoid Arthritis | Sarcopenia
The Christie NHS Foundation Trust

Not yet recruiting

Exploratory Study of EBV DNA Titre Clearance Whilst on Proton Beam Therapy (ClearED)

Head and Neck Cancer | Nasopharyngeal Carcinoma | Nasopharyngeal Cancer | Epstein-Barr Virus
Aga Khan University
University of Karachi

Recruiting

Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls

Polycystic Ovary Syndrome | Insulin Resistance

Pakistan
University of Pisa

Recruiting

Application of Ultra-high Frequency Ultrasonography (UHFUS) to the Study of Gingival Tissues

Periodontitis | Gingivitis

Italy
Samsung Medical Center
Ministry of Science and ICT, Republic of Korea

Recruiting

A Clinical Study for Developing Artificial Intelligence(AI)-Based Clustering Model for Personalized Medicine in Acute Respiratory Failure

Acute Respiratory Failure

Korea, Republic of
Zhuhai Tonbridge Medical Tech. Co., Ltd.

Not yet recruiting

Efficacy and Safety of the Liquid Embolic System (Tonbridge) for Endovascular Treatment of Cerebrovascular Malformations

Intracranial Arteriovenous Malformations

China
University of New Mexico

Not yet recruiting

Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke (CHAMPS-TR)

Stroke, Ischemic
UNC Lineberger Comprehensive Cancer Center
National Center for Advancing Translational Sciences (NCATS)

Not yet recruiting

Kaposi Sarcoma Chemotherapy and Research (KS-CARE) (KS-CARE)

HIV Infections | Kaposi Sarcoma | HIV-associated Kaposi Sarcoma

South Africa
University of Malaya

Recruiting

Radiation Free Fistuloplasty is the Way Forward

Fistulas Arteriovenous

Malaysia
Beijing Jishuitan Hospital
Beijing Friendship Hospital; The Affiliated Hospital of Qingdao University; Beijing... and other collaborators

Recruiting

Research on Key Technology Development and Clinical Application of Small Interactive Spinal Endoscopic Surgery Robot

Lumbar Disc Herniation | Lumbar Spinal Stenosis

China
Riphah International University

Not yet recruiting

Clinimetric Properties of Performance-based Measures of Physical Function in Patients With COPD (COPD)

Chronic Obstructive Pulmonary Disease

Pakistan
Medisch Spectrum Twente
Haukeland University Hospital

Not yet recruiting

Prevalence of EILO Among Children With Asthma

Asthma in Children | Larynx | Dyspnea | Exercise-Induced Bronchoconstriction | Exercise-Induced Bronchospasm | Exercise Induced Laryngeal Obstruction

Netherlands
Chiesi Farmaceutici S.p.A.

Not yet recruiting

Real-World Effectiveness of a Triple Combination BDP/FF/GB in a Single Pressurised Metered Dose Inhaler in COPD Patients (TRIPHY) (TRIPHY)

Chronic Obstructive Pulmonary Disease
Veerle Ruijters
ZonMw: The Netherlands Organisation for Health Research and Development; Curium...

Not yet recruiting

FET-PET-Guided Management of Pseudoprogression in Glioblastoma (FET-POPPING)

Glioblastoma | Radionecrosis of Brain

Netherlands
Hacettepe University

Recruiting

Validity and Reliability of the BETY-Biopsychosocial Scale in Individuals With Coronary Artery Disease

Reliability | Validity

Turkey
Tufts Medical Center
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Recruiting

REACH (Restore Energy, Activity Can Help) Lupus Study (REACH)

Fatigue | Systemic Lupus Erythematosus

United States
Abasyn University Peshawar
Rehman Medical Institute

Recruiting

Low-Load Blood Flow Restriction Training vs Traditional Resistance Training Exercises Following ACLR Surgery

Range of Motion | Strength | Effusion Joint | Skeletal Muscle Hypertrophy | Pain-Knee

Pakistan

Search clinical trials for: GBA1 gene

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