Search clinical trials for: HMGB1 Protein

Total 22161 results

SPARK Biopharma

Completed

SB17170 Phase1 Trial in Healthy Volunteer

Pharmacokinetics | Pharmacodynamics | Safety Issues | Tolerability

Korea, Republic of
Assiut University

Not yet recruiting

MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy

Drug Resistant Epilepsy
Rennes University Hospital

Completed

Effects of Silica and Asbestos Fibres on the Efferocytosis Capacities of Macrophages (MacFibOsis)

History of Exposure to Silica or Asbestosis | Positive Testing for ANA as a Marker of Systemic Autoimmune Diseases

France
Hospital Israelita Albert Einstein
Ohio State University; Federal University of São Paulo

Completed

Ostearthritis Biomarkers and Rehabilitation (Knee)

Osteoarthritis

Brazil
Jing Li

Unknown

Impact of HMGB1 on Diastolic Dysfunction in Hypertensive Patients

Inflammation | Hypertension | Diastolic Dysfunction
Xingui Dai

Completed

HMGB1 Release From Hemorrhagic Shock Patients

Hemorrhagic Shock | Intensive Care Unit | Adult Disease

China
Karolinska University Hospital

Completed

HMGB1 in ICU-survivors

Sepsis | Cognitive Impairment

Sweden
Seoul St. Mary's Hospital

Unknown

Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation (CHIP-SCT)

Acute Graft-versus-host Disease

Korea, Republic of
University Hospital, Grenoble
University Hospital, Marseille

Recruiting

Anti-C1s, Anti-HMGB1 and Anti-C1q Autoantibodies in Systemic Lupus Erythematosus (DYSALARM-322) (DYSALARM-322)

Lupus Erythematosus, Systemic

France
Yonsei University

Completed

The Investigation on the Expression of High Mobility Group Protein Box-1 (HMGB1) in Peripheral Blood of Vitiligo Patients and Healthy Controls According to Clinical Features, Treatment and Disease Activity

Vitiligo

Korea, Republic of
Regeneron Pharmaceuticals

Not yet recruiting

A Study to Learn if 27T51, a Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy, Administered Alone or in Combination is Safe and How Well it Works for Adult Participants With Recurrent or Treatment Resistant Ovarian Cancers

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

United States
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD Patients

Atopic Dermatitis
Kerry Rogers

Not yet recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
M.D. Anderson Cancer Center

Not yet recruiting

A Phase I Study of Hyper-CVAD In Combination With Venetoclax In Pediatric Patients With Relapsed or Refractory Acute Leukemias That Are of the Lymphoid Lineage Including Bi-Phenotypic or Undifferentiated Leukemias

Refractory Acute Leukemia | Undifferentiated Leukemia | Relapsed Acute Leukemia | Bi-Phenotypic Leukemia

United States
First Affiliated Hospital of Zhejiang University
First Affiliated Hospital of Wenzhou Medical University; The Affiliated Hospital... and other collaborators

Recruiting

Primary Multiple Myeloma Who Achieved MRD Negativity After Induction Therapy, ASCT or Not

Multiple Myeloma | Minimal Residual Disease

China
ETH Zurich

Recruiting

Pilot Trial: Bioavailability Animal vs. Plant Protein Drink

Nutrition, Healthy | Leucine Sensitivity

Switzerland
Nanjing IASO Biotechnology Co., Ltd.

Recruiting

A Phase III Study of Eque-cel in Subjects With Len-refractory RRMM (FUMANBA-03) (FUMANBA-03)

Multiple Myeloma

China
The First Affiliated Hospital of Henan University...

Not yet recruiting

Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.

Esophageal Cancer

China
Yunpeng Liu
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

Irinotecan Hydrochloride Liposome Combined With Capecitabine and Lenvatinib in Patients With Biliary Tract Carcinoma

Biliary Tract Carcinoma

China
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Sonrotoclax, Zanubrutinib and CD20mab in Untreated MCL Patients

MCL
University of Central Florida

Not yet recruiting

Collagen Protein Versus Placebo on Muscle Recovery

Anthropometrics: Height and Weight | Isometric Standing and Seated Plantarflexion | Calf Muscle Thickness | Achilles Tendon Length and Thickness | Myotonography of the Calf Musculature and Achilles Tendon | Pain Pressure Threshold of the Calf | Pain Scale | Endurance Calf Test | Dietary Analysis

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Hard-to-Treat Multiple Myeloma

Multiple Myeloma
AbbVie

Not yet recruiting

A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis (Start Up)

Atopic Dermatitis
University of Melbourne
Monash University; University of Adelaide; University of Sydney; The University... and other collaborators

Not yet recruiting

PLatform for Adaptive Trials In Perinatal UnitS - [Core Protocol] (PLATIPUS)

Preterm Birth
Chen Xiaoping

Recruiting

Precision Treatment of Unresectable HCC Guided by Multi-omics Deep Learning Models

HCC | Precision Therapy

China
Takeda

Recruiting

A Survey of Susoctocog Alfa (Genetical Recombination) in Participants With Acquired Haemophilia A

Acquired Hemophilia A

Japan
Uniformed Services University of the Health Sciences
Henry M. Jackson Foundation for the Advancement of Military Medicine

Recruiting

The Effect of Omega-3 Fortified Smoothies on Omega-3 Index and Physical Performance Related Outcomes Among Soldiers (H2FO3)

Nutrition, Healthy

United States
Stanford University
Janssen, LP

Not yet recruiting

Talquetamab & Lenalidomide as Post Stem Cell Transplant Maintenance in Multiple Myeloma

Multiple Myeloma | Post Stem Cell Transplant

United States
University of Bonn

Recruiting

Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic (GCAIO)

Giant Cell Arteritis | Polymyalgia Rheumatica

Germany
Assiut University

Not yet recruiting

Serum Cystatin C for Early Detection of Acute Kidney Injury After Primary Percutaneous Coronary Intervention

Acute Kidney Injury
Izmir Katip Celebi University

Recruiting

Comparison of Salivary Neuropilin-1 (NRP-1), Cotinine and C-Reactive Protein (CRP) Levels With Periodontal Clinical Parameters in Smokers and Non-Smokers With Different Periodontal Diseases

Periodontal Diseases

Turkey
Centre Hospitalier de PAU

Not yet recruiting

Effect of Protein Supplementation on Craving in Subjects Hospitalised for Addiction Treatment (CRAVPROT)

Addiction
Shanghai Chest Hospital
Novartis; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.; BeiGene

Not yet recruiting

Trametinib Plus Anlotinib Combined With Tislelizumab in KRAS-mutant NSCLC

KRAS Mutation-Related Tumors | Advanced Lung Cancer | Refractory Tumor

China
Assiut University

Not yet recruiting

Clinical Outcomes and Prognostic Factors in Multiple Myeloma Patients

Multiple Myeloma
Seoul St. Mary's Hospital

Not yet recruiting

Comparison of Clinical Outcomes According to High-protein Provision in Critically Ill Patients After Abdominal Surgery

Protein Malnutrition

Korea, Republic of
Rejukon Biopharm Inc.

Not yet recruiting

An IIT Clinical Study to Evaluate the Safety and Efficacy of a Single Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis
Jilin University

Not yet recruiting

Efficacy of Upadacitinib After NECS in Vitiligo

Vitiligo
ITB-Med LLC

Recruiting

A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients (AURORA)

ALS

Sweden
CARE ARTHRITIS LTD.

Not yet recruiting

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis (UP-SPOUT)

Psoriatic Arthritis | Spondyloarthritis, Axial
Qilu Hospital of Shandong University

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

Carcinoma, Hepatocellular

China
Durham VA Medical Center
Duke University

Not yet recruiting

Telehealth-based Symptom Management for Veterans Treated With Selinexor (Selinexor)

Multiple Myeloma | Large-cell Lymphoma
Regeneron Pharmaceuticals

Not yet recruiting

A First In Human (FIH) Study to Learn if Different Doses of ALN-ANG3 Are Safe and Well Tolerated in Healthy Adults

Healthy Volunteers
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

Gumarontinib Combined With 3rd EGFR-TKI in Patients With Non-small Cell Lung Cancer.

Non-small Cell Lung Cancer
University of Edinburgh
NHS Lothian

Not yet recruiting

Digital App for Speech & Health Monitoring

Multiple Sclerosis | Parkinson Disease | Motor Neuron Disease | Dementia
Rigshospitalet, Denmark
Aarhus University Hospital Skejby

Recruiting

The Nordic Aortic Valve Intervention Trial 4 (NOTION-4) (NOTION-4)

Heart Diseases | Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Valve Disease, Aortic

Denmark
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Modeling Amyotrophic Lateral Sclerosis With Fibroblasts (FIBRALS)

Amyotrophic Lateral Sclerosis

France
Fudan University

Recruiting

Apatinib Combined With cdk4/6i in First-line Treatment for HR+/HER2- SNF4 Subtype Breast Cancer

Advanced Breast Cancer | HR+/HER2- Breast Cancer

China
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Paroxysmal Nocturnal Hemoglobinuria | PNH | Extravascular Hemolysis
BioMérieux

Recruiting

VIDAS® TBI Performance in Subjects With Mild Traumatic Brain Injury (mTBI)

Mild Traumatic Brain Injury

United States
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China

Search clinical trials for: HMGB1 Protein

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Malawi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations