Pilot Trial: Bioavailability Animal vs. Plant Protein Drink

June 18, 2024 updated by: ETH Zurich

Exploratory Pilot Trial Assessing the Immediate Impact of Animal-based and Plant-based Protein Drinks on Blood Parameters

A pilot study is being conducted to compare a new plant-based protein drink to commercially available animal-based protein drinks. The goal is to assess if the plant-based drink delivers amino acids to the bloodstream as effectively as the animal-based drinks, potentially offering a viable option for those on plant-based diets.

The study will involve approximately 12 healthy adults aged 18-40. Each participant will try all three drinks (the new plant-based drink, a commercial animal-based drink, and another animal-based recipe) on separate days in a randomized order. Before and after (30, 60, and 90 minutes) consuming each drink, a small blood sample will be drawn to measure amino acid levels (leucine).

By comparing the results, the investigators hope to determine if the plant-based drink can match the effectiveness of animal-based protein drinks in delivering essential nutrients. This research could contribute to the development of sustainable and nutritious plant-based protein alternatives.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

12

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion criteria

  • Gender: male and female
  • Age: 18-40 years
  • Signed written informed consent

Exclusion criteria

  • Smoking history
  • Cardiovascular diseases
  • BMI > 35 kg/m2
  • Caffeine consumption < 1 day before the study participation
  • Allergies: Soy, Peas, Milk, Lactose, Fructose
  • High intensity exercise <2 days before study participation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Basic Science
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Animal-based A
A commercially available high protein drink, based on animal proteins (Fresubin Protein Energy)
Dietary supplement: Consumption of protein - rich drink
The participants will drink on of three protein - rich drinks
Active Comparator: Animal-based B
A homemade drink containing animal-based proteins, using a specific animal-based protein isolate mix.
Dietary supplement: Consumption of protein - rich drink
The participants will drink on of three protein - rich drinks
Active Comparator: Plant-based A
A homemade drink containing plant-based proteins, formulated to have the same macronutrient content as the animal-based drinks.
Dietary supplement: Consumption of protein - rich drink
The participants will drink on of three protein - rich drinks

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
leucine content in the blood
Time Frame: 4 hours
Assessment of leucine content in blood before and 30-60-90 min after consumption of drink
4 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

ETH Zurich

Investigators

  • Principal Investigator: Gommaar D'Hulst, PhD, ETH Zurich

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 8, 2024

Primary Completion (Estimated)

June 28, 2024

Study Completion (Estimated)

August 30, 2024

Study Registration Dates

First Submitted

June 13, 2024

First Submitted That Met QC Criteria

June 13, 2024

First Posted (Actual)

June 18, 2024

Study Record Updates

Last Update Posted (Actual)

June 21, 2024

Last Update Submitted That Met QC Criteria

June 18, 2024

Last Verified

June 1, 2024

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2024-00151

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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