Search clinical trials for: PDE-5

Total 14846 results

Bayer
GlaxoSmithKline

Completed

FDA Phase IV - Commitment - Retinal Function Study

Safety
SK Chemicals Co., Ltd.

Terminated

Phase II Trial of SK3530 in Erectile Dysfunction

Male Erectile Dysfunction
University of Minnesota

Withdrawn

Phosphodiesterase-5 (PDE-5) Inhibition in Heart Transplant Recipients

Cardiac Allograft Vasculopathy

United States
Vitaflo International, Ltd
Radboud University Medical Center; Great Ormond Street Hospital for Children...

Completed

Evaluation of PDE MAX (PDE MAX)

Pyridoxine Dependant Epilepsy

Netherlands, United Kingdom
Medispec
Rambam Health Care Campus

Completed

Extracorporeal Shock Wave Therapy for the Treatment of Erectile Dysfunction

Erectile Dysfunction

Israel
Aires Pharmaceuticals, Inc.

Completed

Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States
Samsung Medical Center

Unknown

Understanding of Chest Pain in Microvascular Disease Proved by Cardiac Magnetic Resonance Image (UMPIRE)

Microvascular Angina

Korea, Republic of
Vastra Gotaland Region

Terminated

Effects of PDE-5 Inhibition on Postprandial Hyperglycemia in Type 2 Diabetes

Type 2 Diabetes

Sweden
Vanderbilt University Medical Center

Completed

Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle.

Metabolic Syndrome

United States
Bayer

Completed

Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy (REPLACE)

Pulmonary Arterial Hypertension

Belgium, France, Spain, Portugal, Turkey, United States, Germany, Korea, Republic of, Mexico, Austria, Canada, Denmark, Poland, Italy, Greece, Taiwan, Czechia, Netherlands, Japan, Brazil, United Kingdom
Dr. Soetomo General Hospital

Completed

The Effect of Combination Therapy Using Li-ESWT and PDE-5 Inhibitor in Patients With Erectile Dysfunction

Erectile Dysfunction

Indonesia
Seoul National University Hospital
Dong-A Pharmaceutical Co., Ltd.

Completed

Efficacy Study of PDE-5 Inhibitor and Calcium Channel Inhibitor for the Treatment of Secondary Raynaud Phenomenon

Raynaud Phenomenon

Korea, Republic of
University of California, Irvine

Enrolling by invitation

Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment

Nephrolithiasis

United States
Catharina Ziekenhuis Eindhoven

Recruiting

Therapeutic Oncolytic Monitoring as a Tool for Effective Exposure to 5-FU in Patients With Locally Advanced, Resectable Gastric or Gastro-oesophageal Junction Cancer Treated With Perioperative FLOT (THOMAS FU FLOT)

TDM of 5-FU | Pharmacokinetic Observational Study

Netherlands
Chulalongkorn University
Ramathibodi Hospital; Siriraj Hospital

Completed

The Therapy of Nebido as Mono or in Combination With PDE-5 Inhibitors in Hypogonadal Patients With Erectile Dysfunction

Erectile Dysfunction | Hypogonadism

Thailand
Dr. Frank Behrens
Celgene; Dermatology Department University Hospital Frankfurt

Completed

Preliminary Efficacy and Safety of Apremilast in the Treatment of Acne Conglobata (APACCO)

Acne Conglobata

Germany
Mansoura University

Unknown

Role of Low-intensity Shock Wave Therapy in Penile Rehabilitation Post Nerve Sparing Radical Cysto-prostatectomy

Bladder Cancer

Egypt
Gilead Sciences

Completed

Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1) (ATHENA-1)

Pulmonary Arterial Hypertension

United States
5 Santé
Groupe 5 Santé

Completed

Cognitive Dysfunction in COPD Patients : Role in the Performance of Cognitive-motor Dual Task Situation? (DysCo)

Chronic Obstructive Pulmonary Disease
Case Comprehensive Cancer Center

Recruiting

Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions

Invasive Breast Cancer

United States
Marie Forgie
Aurora Health Care

Completed

Foley Catheter for Induction of Labor

Induction of Labor | Foley Catheterization | 5 French Stylette

United States
Alere San Diego

Completed

Alere Triage fs B-type Natriuretic Peptide (BNP) Method Comparison Evaluation (ABC)

Triage | Specimens With BNP Values of 5 to 5000 pg/ml
California Institute of Renal Research

Recruiting

A Single Arm sTudy to Evaluate the Effectiveness of EndoAVF in a Pre-dialysis Population (STEP Study)

CKD Stage 4 | CKD Stage 5 | CKD Stage 3

United States
United Therapeutics

Completed

FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, United Kingdom, Canada, Spain, Australia, Israel, Germany, Belgium, France, Austria, Italy, Poland, Ireland, Netherlands
Heidelberg University

Completed

Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and Clinical Disease Status in Patients With PAH (EPIC)

Pulmonary Arterial Hypertension

Germany
McGill University Health Centre/Research Institute...

Recruiting

Safety and Efficacy of Canagliflozin in Advanced CKD (SIP-AKiD)

ESRD | CKD Stage 4 | CKD Stage 5

Canada
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Treatment for Caffeine Dependence

Caffeine Use Disorder (DSM-5 Condition for Further Study)

United States
Taichung Veterans General Hospital

Recruiting

Efficacy and Toxicity of SCART

Tumor Size Greater Than or Equal to 5 cm

Taiwan
Istanbul Medipol University Hospital

Not yet recruiting

The Effect of Futsal Training on Physical Fitness in Amateur Futsal Players

Physical Fitness | Futsal

Turkey
Loulou Foundation

Active, not recruiting

Observational Study in Patients With Cyclin-dependent Kinase-like 5 Deficiency Disorder (CANDID)

Cyclin-Dependent Kinase-Like 5 Deficiency Disorder

United States, Spain, Italy, France, Canada, Germany, United Arab Emirates
University of Colorado, Denver
Pfizer

Active, not recruiting

Study of Efficacy, Safety and Tolerability of Crisaborole and PF-07038124 With and Without NBUVB in Vitiligo

Vitiligo

United States
Teesside University
University of Sunderland

Recruiting

The Effect of 6 Weeks Jump Training on Sand Versus Hard Surfaces on Jump Landing and Performance in Young Females

Frontal Plane Projection Angle | Maximal Countermovement Jump | Repeated 10/5

United Kingdom
5 Santé

Completed

Impact of Hypnosis Intervention on the Emotional Dimension of Dyspnea in Patients With COPD.

Chronic Obstructive Pulmonary Disease

France
5 Santé

Completed

Dyspnea Threshold During 6 Minutes Walk Test (SD6)

COPD

France
University of Copenhagen
Glostrup University Hospital, Copenhagen

Terminated

Phosphodiesterase (PDE) Inhibitors Effect on Cognitive Deficits Associated to Schizophrenia

Schizophrenia | Cognitive Deficits

Denmark
Lee's Pharmaceutical Limited

Not yet recruiting

Phase III Clinical Trial Evaluating the Efficacy and Safety of 5-aminolevulinic Acid (5-ALA）

5-aminolevulinic Acid | Fluorescence-guided Resection

China
Tanta University

Completed

Lidocaine 5% Patch Supplementation to Intra-articular Bupivacaine Dexmedetomidine After Arthroscopic Knee Surgery

Dexmedetomidine | Arthroscopic Knee Surgery | Lidocaine 5% Patch | Intra-articular
5 Santé

Completed

Physiopathology of Lower Cortical Activation in COPD Patients: Contribution of Cortical Neuromodulation

Physiology

France
5 Santé

Completed

Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients

Physiology | Neurophysiology

France
5 Santé

Completed

Motivational Parameters Associated With Physical Activity and Sedentary Behaviors Among Persons With Chronic Diseases

Health Behavior

France
5 Santé

Completed

Correction of Exercise-induced Desaturation by Acute Oxygen Supply and Exercise Responses in COPD (RePox-1)

Chronic Obstructive Pulmonary Disease | Oxygen/Therapeutic Use

France
5 Santé

Completed

Does Muscle Wasting Always Mean Muscle Weakness? A Prevalence Study in COPD (M2W)

COPD

France
Cedars-Sinai Medical Center

Completed

PDE Inhibitors in DMD Study (Acute Dosing Study)

Duchenne Muscular Dystrophy

United States
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
Medicure

Recruiting

Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency (MEND-PNPO)

Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency

United States, Australia
United Therapeutics

Withdrawn

FREEDOM DR: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor or as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, Australia, Mexico
University of California, San Francisco
London School of Hygiene and Tropical Medicine; National Institute of Allergy... and other collaborators

Completed

Trial of Proactive Community Case Management to Reduce Child Mortality (Pro-CCM)

Access to Health Care | Under-five Child Mortality
University Medical Centre Ljubljana

Completed

PDE-4 Inhibitor Roflumilast and GLP-1 Agonist Liraglutide in Polycystic Ovary Syndrome

Obesity | PCOS

Slovenia
Heinrich-Heine University, Duesseldorf

Recruiting

Vaccination Against COVID-19 in Chronic Kidney Disease

Vaccine Response Impaired | Chronic Kidney Disease Stage 5 on Dialysis | Chronic Kidney Disease Stage 5 With Transplant

Germany
Mayo Clinic
National Institutes of Health (NIH)

Completed

Low Dose Intravenous (IV) Infusion of BNP in the Presence and Absence of Acute Type V Phosphodiesterase (PDE V) in Improving Renal Function in Hospitalized Chronic Heart Failure (CHF) Patients With Renal Dysfunction (Aim 3 BNP/PDEV)

Heart Failure | Renal Dysfunction

Search clinical trials for: PDE-5

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