Search clinical trials for: Phase II study, clinical trial

Total 113416 results

Yun-fei Xia

Not yet recruiting

PFLL Combined With PD-1 Antibody With or Without FMT for Oligometastatic NPC,a Phase III ,Open, Randomized Clinical Trial.

Nasopharyngeal Carcinoma
Yunnan Cancer Hospital

Recruiting

The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial. (WINDOW)

Clinical Complete Response Rate With Negative MRD

China
Luye Pharma Group Ltd.

Recruiting

Phase II Clinical Trial to Evaluate the Efficacy and Safety of LPM3480392 Injection for Moderate to Severe Pain After Orthopedic Surgery

Pain, Postoperative

China
Xijing Hospital

Not yet recruiting

Efficacy and Safety of Neoadjuvant Sintilimab Plus FLOT Versus Sintilimab Plus SOX Phase II Clinical Trial for Patients With Locally Advanced Gastric Cancer

Sintilimab | Neoadjuvant Chemotherapy | Locally Advanced Gastric Cancer
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial

MF,PMF,PPV-MF,PET-MF

China
Jinghui Wang

Recruiting

A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.

Lung Cancer

China
Swiss Group for Clinical Cancer Research

Not yet recruiting

Darolutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Metastatic Castration-resistant Prostate Cancer

Switzerland
Summit Therapeutics
Akeso

Recruiting

Phase III Study of AK112 for NSCLC Patients

Non-Squamous Non-small Cell Lung Cancer

Canada, United States, Spain, Italy, France, United Kingdom
Eli Lilly and Company

Recruiting

The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Renal Function in Adults Living With Obesity (TRIUMPH-OUTCOMES)

Overweight and Obesity

United States, Australia, Italy, Hungary, Netherlands, Canada, France, Spain, United Kingdom, Germany, Argentina, Czechia, Israel, Austria, Belgium, Greece, Turkey, Mexico, Romania, Brazil, India, Slovakia, Poland, Puerto Rico, Denmark
Sensorion

Not yet recruiting

A Phase I/II Clinical Trial With SENS-501 in Children Suffering From Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations (AUDIOGENE)

Otorhinolaryngologic Diseases | Ear Diseases | Hearing Disorders | Deafness | Hearing Loss, Sensorineural | Congenital Deafness | DFNB9 | OTOF Gene Mutation

France
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma

Bladder Cancer

China
Astrogen, Inc.

Recruiting

Phase III Clinical Trial to Evaluate the Efficacy and Safey of AST-001 in ASD Children

Autism Spectrum Disorder

Korea, Republic of
Zhejiang Cancer Hospital

Not yet recruiting

Eribulin Combined With Sintilimab as First-line Treatment for Unresectable Locally Advanced or Metastatic HER2-negative Breast Cancer:A Multicenter, Single-arm,Phase II Clinical Trial

Metastatic Breast Cancer

China
Dizal Pharmaceuticals

Recruiting

A Phase II Clinical Trial of DZD9008 in Combination With AZD4205 in Standard Treatment Failed NSCLC Patients With EGFR Mutations (WU-KONG21)

Non-small Cell Lung Cancer

China
Biocomposites Ltd
MCRA

Not yet recruiting

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. (BLADE OPU2)

Osteomyelitis | Pressure Ulcer, Stage IV
Instituto de Investigación Hospital Universitario...
Instituto de Salud Carlos III

Not yet recruiting

Efficacy, Safety and Cost-efficacy of a Pre-emptive Genotyping Strategy in Patients Receiving Statins (PREVESTATGx)

Cardiovascular Diseases | Dyslipidemias | Statin Adverse Reaction | Pharmacogenic Myopathy

Spain
GCP-Service International West GmbH
Saint-Louis Hospital, Paris, France; University of Florence; Medical University... and other collaborators

Not yet recruiting

RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms ((MDS))

Low Risk Myelodysplastic Syndromes

Spain, Poland, Italy, Germany, France
Sun Yat-sen University

Recruiting

A Multi-center, Randomized, Double-blind, Phase II/III Clinical Trial of AK104 or Placebo in Combination With Chemotherapy as Second-line or More Lines for Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)

Recurrent or Metastatic Nasopharyngeal Carcinoma

China
Takeda

Recruiting

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's Disease

United States, Australia, France, Taiwan, Hungary, Korea, Republic of, Spain, Switzerland, China, Japan, Belgium, Canada, Germany, Italy, Poland, Romania, United Kingdom, Czechia, Denmark, Greece, Norway, Slovakia, Netherlands
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) Cancer

Squamous Cell Carcinoma of the Head and Neck | Drug Therapy | Oropharynx | Human Papillomavirus Viruses | Cancer Vaccine

United States
Chang Gung Memorial Hospital

Not yet recruiting

Dendritic Cell Vaccination to Prevent Hepatocellular Carcinoma Recurrence After Liver Resection-phase II Clinical Trial

Hepatocellular Carcinoma
Genmab
AbbVie

Recruiting

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma (EPCORE™FL-2)

Follicular Lymphoma (FL)

United States, Puerto Rico, Australia, Israel, Korea, Republic of, Romania, Serbia, Spain, Taiwan, Croatia, Czechia, France, Germany
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
Shanghai Chest Hospital

Not yet recruiting

Neoadjuvant Adebrelimab Plus Chemotherapy for Resectable ESCC: a Single Arm, Prospective Phase 2 Clinical Trial

Esophageal Squamous Cell Carcinoma

China
Lee's Pharmaceutical Limited

Not yet recruiting

Phase III Clinical Trial Evaluating the Efficacy and Safety of 5-aminolevulinic Acid (5-ALA）

5-aminolevulinic Acid | Fluorescence-guided Resection

China
Natural Wellness Egypt

Not yet recruiting

NW Roselle in Grade 1 Essential Hypertension: Phase III Clinical Trial

Essential Hypertension
Tianjin Medical University Cancer Institute and...

Recruiting

Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer

Non-small-cell Lung Cancer

China
Zhejiang Cancer Hospital

Not yet recruiting

The Efficacy and Safety of Lenvatinib Combined With Sindilimab and Nab-paclitaxel in the First-line Treatment for Recurrent and Metastatic Triple Negative Breast Cancer: a Phase Ib/IIa Clinical Trial.

Breast Neoplasms

China
Xuekui Liu

Not yet recruiting

A Prospective, Single-arm Phase II Clinical Trial of Tislelizumab Combined With Platinum Doublet Neoadjuvant Therapy to Improve Mandibular Preservation in Resectable Locally Advanced Oral Squamous Cell Carcinoma. (B2023-153)

Oral Squamous Cell Carcinoma
Central Hospital, Nancy, France

Not yet recruiting

Combination of Everolimus and 177Lu-DOTATATE in the Treatment of Grades 2 and 3 Refractory Meningioma: a Phase IIb Clinical Trial (ELUMEN)

Meningioma

France
The Methodist Hospital Research Institute

Recruiting

Phase II Clinical Trial of Interleukin-2 in AD

Alzheimer Disease

United States
Institute of Medical Biology, Chinese Academy of...
Henan Center for Disease Control and Prevention

Recruiting

Phase II Clinical Trial of the Inactivated Rotavirus Vaccine

Diarrhea | Rotavirus Infections

China
Sinovac Biotech Co., Ltd

Recruiting

Inactivated Bivalent Enterovirus Vaccine (Vero Cell) Phase I/II Clinical Trial

Hand, Foot and Mouth Disease | Herpangina

China
Sinovac Biotech Co., Ltd

Recruiting

A Phase III Clinical Trial of Quadrivalent Influenza Vaccine in Healthy Subjects Aged 6 to 35 Months

Seasonal Influenza

China
Nanjing Leads Biolabs Co.,Ltd

Recruiting

A Phase I/II Clinical Trial of LBL-034 in Patients With Relapsed Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Shanghai YingLi Pharmaceutical Co. Ltd.
Shanghai HyaMab Biotech Co.,Ltd.

Not yet recruiting

A Phase Ib/II Clinical Trial of PE0116 and PE0105 Injection in Treatment of Patients With Advanced Solid Tumor

Advanced Solid Tumors
Empros Pharma AB
CTC Clinical Trial Consultants AB

Recruiting

A Phase 1 Study to Evaluate EMP22 PD and EMP16 PK Versus Xenical® in Healthy Volunteers

Overweight or Obesity

Sweden
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma (SCC)

United States
Medical College of Wisconsin

Not yet recruiting

Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma

Multiple Myeloma
InflaRx GmbH

Recruiting

Phase III Trial to Investigate Efficacy and Safety of Vilobelimab in Ulcerative Pyoderma Gangrenosum

Pyoderma Gangrenosum

United States, Spain, France, Italy, Australia, Germany, Hungary, Poland, Switzerland
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase Ib/II Study Confirmed Inhibition of Autophagy Synergizes Anti-tumor Effect of High Dose CDK4/6i

Inhibition of Autophagy Synergizes Anti-tumor Effect

China
Mridula George, MD

Recruiting

OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer

Triple Negative Breast Cancer (TNBC)

United States
AIM Vaccine Co., Ltd.
Zhejiang Provincial Center for Disease Control and Prevention

Not yet recruiting

A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

SARS-CoV-2

China
Centre Georges Francois Leclerc

Not yet recruiting

Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %. (IMMUNOMEK)

Non-Small Cell Lung Cancer
Otsuka Beijing Research Institute

Recruiting

Phase II Clinical Trial of OPS-2071 in the Treatment of Irritable Bowel Syndrome of Diarrhea Type

Irritable Bowel Syndrome of Diarrhea Type (IBS-D)

China
National Vaccine and Serum Institute, China
Lanzhou Institute of Biological Products Co., Ltd

Not yet recruiting

Phase III Clinical Trial to Evaluate the Human Norovirus Bivalent (GⅠ.1/GⅡ.4)Vaccine，Recombinant (Hansenula Polymorpha)

Norwalk Gastroenteritis | Norovirus Infections
Shionogi

Recruiting

Phase 3 Study of S-217622 in Prevention of Symptomatic SARS-CoV-2 Infection (SCORPIO-PEP)

SARS-CoV-2 Infection

Japan, United States
Reata, a wholly owned subsidiary of Biogen

Recruiting

A Phase 2 Study of RTA 901 (BIIB143) in Participants With Diabetic Peripheral Neuropathic Pain (CYPRESS) (CYPRESS)

Diabetic Peripheral Neuropathic Pain

United States
Eli Lilly and Company
Rigel Pharmaceuticals

Recruiting

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, France, United Kingdom, Argentina, Mexico, India, Czechia, Germany, Slovakia
Dong-A ST Co., Ltd.

Not yet recruiting

Phase III Clinical Trial of DA-5212 in Patients With Functional Dyspepsia

Functional Dyspepsia

Korea, Republic of

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