Search clinical trials for: Sonic Hedgehog inhibitors
Total 64458 results
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University Hospital, LilleSun Pharmaceutical Industries LimitedNot yet recruitingBasal Cell Carcinoma | Radiotherapy; Complications
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St. Jude Children's Research HospitalRecruitingMedulloblastomaUnited States
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St. Jude Children's Research HospitalNovartis PharmaceuticalsCompletedGlioma | Neoplasms | Glioblastoma | Neoplasms, Neuroepithelial | Central Nervous System Neoplasms | Brain Cancer | Brain Tumor | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Ganglioglioma | Anaplastic Ependymoma | Anaplastic Oligodendroglioma | Pineoblastoma | Recurrent Medulloblastoma | CNS Tumor | Pediatric... and other conditionsUnited States
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St. Jude Children's Research HospitalEli Lilly and CompanyActive, not recruitingBrain Cancer | Brain Tumor | Medulloblastoma | Brain Tumor, Recurrent | CNS Tumor | Medulloblastoma Recurrent | CNS Cancer | Medulloblastoma, Non-WNT/Non-SHH | Brain Tumor, Pediatric | CNS Neoplasm | Brain Tumor, Refractory | Medulloblastoma, Non-WNT/Non-SHH, Group 3 | Medulloblastoma, Non-WNT/Non-SHH, Group 4United States
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St. Jude Children's Research HospitalNational Cancer Institute (NCI); Genentech, Inc.Active, not recruitingMedulloblastomaUnited States, Canada, Australia, New Zealand
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Clinica Universidad de Navarra, Universidad de...Unknown
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Ronald BuckanovichGenentech, Inc.RecruitingPARP Inhibitor | Platinum-Resistant Fallopian Tube Carcinoma | Platinum-Resistant Primary Peritoneal Carcinoma | Hedgehog InhibitorUnited States
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Maastricht University Medical CenterSun Pharmaceutical Industries LimitedRecruitingCarcinoma | Carcinoma, Basal Cell | Skin Cancer | Basal Cell Nevus Syndrome | Neoplasms, Basal Cell | Basal Cell Carcinoma | Locally Advanced Basal Cell Carcinoma | Metastatic Basal Cell Carcinoma | Gorlin Syndrome | Basal Cell Tumor | Neoplasm of SkinNetherlands
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Hangzhou Cancer HospitalRecruitingEsophageal Diseases | Esophageal Squamous Cell Carcinoma | Esophageal NeoplasmChina
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National Cancer Institute (NCI)Active, not recruitingGlioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditionsUnited States, Puerto Rico, Guam
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Cheng-Chia (Fred) WuFocused Ultrasound FoundationActive, not recruitingDiffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-MutantUnited States
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Pediatric Brain Tumor ConsortiumNational Cancer Institute (NCI); American Lebanese Syrian Associated Charities...SuspendedMedulloblastoma, ChildhoodUnited States
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National Cancer Institute (NCI)Active, not recruitingPancreatic Ductal Adenocarcinoma | Recurrent Pancreatic Carcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Pancreatic Acinar Cell Carcinoma | Adult Solid NeoplasmUnited States
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OHSU Knight Cancer InstituteOregon Health and Science UniversityTerminatedPrimary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditionsUnited States
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OHSU Knight Cancer InstituteGenentech, Inc.; Oregon Health and Science UniversityWithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent... and other conditionsUnited States
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Endeavor Biomedicines, Inc.CompletedIdiopathic Pulmonary FibrosisAustralia
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Sarit AssoulineCompleted
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PfizerCompletedLeukemia, Myeloid, AcuteUnited States, Spain, Canada, Israel, Korea, Republic of, Taiwan, France, Australia, Germany, Mexico, Japan, Sweden, China, Austria, Belgium, Czechia, Hungary, Italy, Poland, Romania, Russian Federation, United Kingdom
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Cheng-Chia (Fred) WuFocused Ultrasound FoundationActive, not recruitingDiffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Diffuse Pontine and Thalamic GliomasUnited States
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Dallas VA Medical CenterActive, not recruitingEsophageal CancerUnited States
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National Cancer Institute (NCI)CompletedExtensive Stage Small Cell Lung Carcinoma | Recurrent Small Cell Lung CarcinomaUnited States
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Novartis PharmaceuticalsCompletedAdvanced Solid TumorUnited States
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PfizerCompletedAcute Myeloid LeukemiaUnited States, Spain, Germany, Italy, Poland, Canada
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Sidney Kimmel Comprehensive Cancer Center at Johns...Novartis Pharmaceuticals; The Skip Viragh FoundationTerminatedPancreatic Ductal AdenocarcinomaUnited States
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Hospital de Clinicas de Porto AlegreUnknownBasal Cell Carcinoma | Hedgehog PathwayBrazil
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Centre Leon BerardMinistry of Health, FranceTerminatedHistologically Confirmed Medulloblastoma | Activation of the Sonic Hedgehog (SHH) PathwayFrance, Italy, Switzerland, United Kingdom
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Sidney Kimmel Comprehensive Cancer Center at Johns...Genentech, Inc.; Celgene Corporation; Stand Up To CancerCompletedMetastatic Pancreatic CancerUnited States
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Medical University of WarsawUnknownBacterial Infections | Varicocele | Viral Infection | Sonic Hedgehog Expression | VEGF ExpressionPoland
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National Cancer Institute (NCI)CompletedRecurrent Uterine Corpus Sarcoma | Chondrosarcoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult... and other conditionsUnited States
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Memorial Sloan Kettering Cancer CenterNovartis PharmaceuticalsCompleted
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National Cancer Institute (NCI)CompletedRecurrent Pancreatic Carcinoma | Stage IV Pancreatic CancerUnited States
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GNT PharmaUnknownIschemic StrokeKorea, Republic of
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Genentech, Inc.Completed
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Infinity Pharmaceuticals, Inc.CompletedMetastatic Pancreatic CancerUnited States, Canada
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Anne ChangNovartisCompletedBasal Cell CarcinomaUnited States
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National Cancer Institute (NCI)CompletedAdenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage IV Pancreatic CancerUnited States
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National Cancer Institute (NCI)TerminatedStage IV Breast Cancer | Recurrent Breast Carcinoma | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast CarcinomaUnited States
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Genentech, Inc.CompletedMetastatic Colorectal Cancer | Ovarian Cancer | Basal Cell CarcinomaUnited States
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Third Affiliated Hospital, Sun Yat-Sen UniversityNational Natural Science Foundation of ChinaUnknownArthritis, Rheumatoid | Neovascularization, Pathologic | Synovitis
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Jean-Luc Van LaethemRoche Pharma AGUnknownPancreatic Adenocarcinoma ResectableBelgium
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Ohio State UniversityPatient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...Not yet recruitingPreeclampsia | Gestational Hypertension | Hypertensive Disorders of PregnancyUnited States
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Tang-Du HospitalRecruitingSmall Cell Lung CancerChina
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Chang Gung Memorial HospitalNot yet recruiting
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University of East AngliaClinical Research and Trials Unit (Norfolk & Norwich University Hospital,...Recruiting
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Mikko NiemiUniversity of HelsinkiRecruiting
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National Aeronautics and Space Administration (NASA)Recruiting
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Regeneron PharmaceuticalsNot yet recruitingFallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal CarcinomaUnited States
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The First Affiliated Hospital with Nanjing Medical...Recruiting
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Radboud University Medical CenterNot yet recruitingADHD - Combined Type | Kbg Syndrome