Search clinical trials for: biological clock

Total 4405 results

Xuanwu Hospital, Beijing
Merck Serono Co., Ltd., China; Institute of Zoology, Chinese Academy of Sciences and other collaborators

Not yet recruiting

Pilot Study on Evaluating the Geroprotective Effect of Metformin (AGE-M)

Aging | Metformin

China
Stanford University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Psychobiological Interventions in Pregnancy (PIP)

Pregnancy Complications | Pregnancy, High Risk | Depression, Anxiety | Mental Health Issue | Biological Clock Disturbance

United States
Michaël RACODON

Recruiting

Time of Exercise Re-training With Chronic Obstructive Pulmonary Disease (COPD) (CHRONOBIO)

Respiratory Diseases

France
National University of Singapore
Agency for Science, Technology and Research; AMILI Pte. Ltd.

Recruiting

Does Alpha-ketoglutarate Supplementation Lower BiologicaL agE in Middle- Aged Adults? (ABLE)

Aging

Singapore
Hospital of South West Jutland
Odense University Hospital; Rigshospitalet, Denmark; University of Southern Denmark and other collaborators

Recruiting

Sleep, Obesity and Mental Disease - Biological Markers for the Evaluation of Circadian Rhythmicity (SOMBER)

Obesity | Schizophrenia | Bipolar Disorder | Circadian Rhythm Disorders

Denmark
Université de Caen Normandie
Région Normandie

Recruiting

Vestibular Stimulation, Exercise and Light Optimization for Circadian Clock Enhancement (Velocce) (velocce)

Healthy Aging

France
University of Athens
Hellenic Sepsis Study Group

Recruiting

Functionality of Endogenous Biological Clock in Sepsis

Sepsis | Circadian Rhythm Disorders

Greece
Assaf-Harofeh Medical Center
Hadassah Medical Organization; Western University, Canada

Not yet recruiting

Influence of Circadian Clock on Hormonal, Metabolic, Neurocognitive Markers in Adolescents With and Without Diabetes

ADHD | Memory Impairment | T1DM | Sleep Disorders, Circadian Rhythm
Assistance Publique - Hôpitaux de Paris

Completed

Impact of Dysregulation of Core Body Temperature on Sleep in Patients With Hypohidrotic Ectodermal Dysplasia (DEH-Somno)

Hypohidrotic Ectodermal Dysplasia

France
Sakarya University

Completed

The Effect of Nursing Care on Circadian Rhythm

Sleep Quality | Circadian Rhythm | Chronobiology Disorders | Nursing Care | Biological Clock Disturbance

Turkey
Industrial Farmacéutica Cantabria, S.A.

Completed

Oral Supplementation With AM3, Hesperidin and Spermidine Supplementation on Immunity Response and Biological Age.

Healthy

Spain
Leiden University
BioClock Consortium; Caring Univeristies

Completed

Feasibility Trial i-Sleep & BioClock Intervention

Insomnia

Netherlands
University Hospital, Caen

Completed

DEEPTIME: Human Adaptation in Time Underground Isolation (DEEPTIME)

Sleep | Cognitive Dysfunction | Physiological Stress

France
National Science Council, Taiwan

Completed

Melatonin Receptor Agonist and Peripheral Biological Markers

Insomnia
Yale University
Children's Hospital Los Angeles

Completed

Biological Clock Dysfunction in Optic Nerve Hypoplasia

Biological Clock Dysfunction | Optic Nerve Hypoplasia

United States
Uppsala University
The Swedish Research Council

Unknown

Biorhythms in Metabolic Tissues

Healthy | Sleep Deprivation | Metabolic Disturbance | Biological Clocks

Sweden
Takeda

Completed

Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers

Circadian Dysregulation

United States
University Hospital, Bordeaux

Completed

Aging, Sleep, Cognitive Process (SOMVIE)

BIOLOGICAL CLOCKS

France
Brigham and Women's Hospital
National Center for Complementary and Integrative Health (NCCIH)

Completed

Effects of Vitamin B12 on the Body's Internal Clock

Sleep Disorders, Circadian Rhythm

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Refractory Differentiated Thyroid Gland Carcinoma
SWOG Cancer Research Network
National Cancer Institute (NCI)

Not yet recruiting

Testing Whether the Addition of Carboplatin Chemotherapy to Cabazitaxel Chemotherapy Will Improve Outcomes Compared to Cabazitaxel Alone in People With Castrate-Resistant Prostate Cancer That Has Spread Beyond the Prostate to Other Parts of the Body

Castration-Resistant Prostate Carcinoma | Stage IVB Prostate Cancer AJCC v8
Yuanquan Yang

Not yet recruiting

Siltuximab for the Prevention of Severe Immune-Related Adverse Events During Immune Checkpoint Inhibitor Rechallenge in Patients With Advanced Cancer, CIRES Trial

Advanced Malignant Solid Neoplasm | Hematopoietic and Lymphatic System Neoplasm

United States
University of British Columbia

Recruiting

The UBC Long-distance Triathlon Adaptation Study (ULTRA)

Healthy Participants

Canada
Kerry Rogers

Not yet recruiting

Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

New Therapeutic Strategy Against Preeclampsia (APHERESE2)

Preeclampsia

France
National Cancer Institute (NCI)

Not yet recruiting

Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Hard-to-Treat Multiple Myeloma

Multiple Myeloma
InventVacc Biologicals Inc.
Hia Consortium

Recruiting

A Study to Evaluate Safety and Immunogenicity of Haemophilus Influenzae Serotype A Vaccine

Haemophilus Influenzae Meningitis | Invasive Haemophilus Influenzae Disease

Canada
Taichung Veterans General Hospital
Chang Gung Memorial Hospital; National Cheng-Kung University Hospital; E-DA Hospital and other collaborators

Recruiting

Taiwan Severe Asthma Biologic Registry (TARGET)

Asthma | Pulmonary Disease

Taiwan
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic Cancer

Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Advanced Pancreatic Adenocarcinoma | Unresectable Pancreatic Ductal Adenocarcinoma

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Regorafenib in Combination With Venetoclax and Azacitidine for the Treatment of Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Myelodysplastic Syndrome/Acute Myeloid Leukemia

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular Lymphoma | Refractory Grade 2 Follicular Lymphoma | Refractory Grade 3a Follicular Lymphoma

United States
Bruce Cree
Kyverna Therapeutics

Recruiting

A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis

Progressive Multiple Sclerosis

United States
Medical University of Lodz
Poznan University of Medical Sciences; Medical Research Agency, Poland; Clinical... and other collaborators

Not yet recruiting

Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis (COMBO-UC)

Inflammatory Bowel Diseases | Ulcerative Colitis
Centre Hospitalier Universitaire, Amiens
Groupe Hospitalier Pitie-Salpetriere

Recruiting

Study of the Relationship Between Clinical, Imaging and Biological Data in Patients With Squamous Cell Carcinoma of the Tongue (ClimaBio)

Squamous Cell Carcinoma | Proton Magnetic Resonance Spectroscopy | Transcriptomics | Soft Tissue Tumors of the Tongue

France
Anhui Medical University

Not yet recruiting

Establishment of Reproductive Cohort and Prediction Model of Genetic Counseling for Mitochondrial Genetic Diseases

Mitochondrial Diseases
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Humanized CD19-Specific CAR T Cells for the Treatment of Patients With Positive Relapsed or Refractory CD19 Positive B-Cell Acute Lymphoblastic Leukemia

Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Manipulating E-Cigarette Nicotine to Promote Public Health

Tobacco-Related Carcinoma

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Evaluating the Impact of a Virtually Supervised Exercise Intervention and Group Counseling on Inflammation and the Microbiome of Smokers at High Risk for Lung Cancer, BE FIT Trial

Lung Carcinoma

United States
Jonsson Comprehensive Cancer Center
Telix Pharmaceuticals (Innovations) Pty Limited

Not yet recruiting

An Investigational Scan (89Zr-DFO-GmAb PET/CT) Compared to Contrast-Enhanced CT for the Detection of Recurrent Clear Cell Renal Cell Cancer After Surgery Comparing Carbonic Anhydrase IX (CAIX) PET CT to Conventional PET CT for Post-Op Staging in Kidney Cancer

Clear Cell Renal Cell Carcinoma | Stage III Renal Cell Cancer | Sarcomatoid Renal Cell Carcinoma | Stage IV Renal Cell Cancer | Stage II Renal Cell Cancer

United States
University Hospital, Toulouse

Not yet recruiting

Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies. (OSCAR)

Bone Disorder
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E Mutation

Thyroid Gland Follicular Carcinoma | Thyroid Gland Papillary Carcinoma | Thyroid Gland Oncocytic Carcinoma

United States
University of Washington

Not yet recruiting

Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma | Ann Arbor Stage II Marginal Zone Lymphoma | Ann Arbor Stage III Marginal Zone Lymphoma and other conditions

United States
King Saud University

Not yet recruiting

Effects of Lifestyle Intervention in the Biological Aging in Prediabetes

PreDiabetes | Marker; Structural
National Cancer Institute (NCI)

Not yet recruiting

Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

Metastatic Urothelial Carcinoma | Unresectable Urothelial Carcinoma
Nantes University Hospital
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Biological, Prospective Study Evaluating the Dosage of Plasma Cytokines Including the FLT3 Ligand and IL6 of Patients Treated With Non-intensive Chemotherapy (CYTOK-AZA)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia

France
Mayo Clinic

Recruiting

Fasting Mimicking Diet for Reducing Immune Related Adverse Events for Cancer Patients on Immune Checkpoint Inhibitors, FMD-ICI Trial

Malignant Solid Neoplasm | Melanoma | Renal Cell Carcinoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Lung Small Cell Carcinoma

United States
Roswell Park Cancer Institute

Not yet recruiting

Tamoxifen and Pegylated Liposomal Doxorubicin for the Treatment of Patients With Metastatic or Inoperable, Locally Advanced Triple Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Unresectable Triple-Negative Breast Carcinoma

United States
Jonsson Comprehensive Cancer Center
Boston Scientific Corporation

Not yet recruiting

Yttrium-90 (Y90) Radioembolization for the Treatment of Early Stage Renal Cell Carcinoma, The RENEGADE Trial

Stage I Renal Cell Cancer | Stage II Renal Cell Cancer

United States
Meander Medical Center
Health Holland

Recruiting

Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery (ProTex)

Prolapse | Colorectal Disorders | Cystocele | Rectocele | Prolapse Genital | Enterocele | Prolapse Bladder | Prolapse Pelvic | Prolapse Uterus | Prolapse; Cervix | Prolapse Rectal

Netherlands
Auburn University
National Institute on Drug Abuse (NIDA); Wayne State University

Not yet recruiting

Cannabinoids and Biological Reactivity to Stress (COBRAS)

Cannabis Use Disorder

Search clinical trials for: biological clock

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