Search clinical trials for: hypoxia-inducible factor 2 alpha (HIF-2α, HIF-2 alpha)

Total 82271 results

Peloton Therapeutics, Inc.

Active, not recruiting

A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)

Kidney Cancer | Renal Cell Carcinoma | Renal Cancer | Renal Cell Carcinoma (RCC) | Renal Cell Cancer Metastatic | Kidney | Clear Cell Renal Cell Carcinoma (ccRCC) | Renal Cell Carcinoma Recurrent | Renal Cell Cancer, Recurrent

United States
NiKang Therapeutics, Inc.

Recruiting

A Study of NKT2152, a HIF2α Inhibitor, in Patients With Advanced Clear Cell Renal Cell Carcinoma

Kidney Cancer | Kidney Neoplasms | Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Hypoxia | Metastatic Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Renal Cancer | Advanced Renal Cell Carcinoma | Renal Neoplasms | ccRCC | Refractory Renal Cell Carcinoma | Hypoxia Inducible Factor (HIF) | HIF2α... and other conditions

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018)

Carcinoma, Renal Cell

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013)

Carcinoma, Renal Cell

United States, Australia, Belgium, Greece, Ireland, Israel, Netherlands, Russian Federation, United Kingdom
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); Peloton Therapeutics, Inc.

Completed

HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma (PT2385)

Recurrent Glioblastoma

United States
Assiut University

Not yet recruiting

Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α.

Hif-1α Covid-19
GlaxoSmithKline

Terminated

Anemia Study in Chronic Kidney Disease (CKD) : Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat -Forearm Blood Flow (ASCEND-FBF)

Anaemia

United Kingdom
Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Recruiting

Talocalcaneal Angle in Calcaneal Spur Formation

Plantar Fascitis | Foot Callus

Turkey
Zagazig University

Unknown

Second Trimester Pregnancy Termination in Women With Previous Caesarean Sections

Second Trimester Abortion

Egypt
Mersin University

Recruiting

Effects of Information-Motivation-Behavioral Skills Model on Disease Management of Adolescents With Epilepsy

Nursing Caries

Turkey
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005)

Carcinoma, Renal Cell

Hungary, United States, Brazil, Canada, Chile, Colombia, Czechia, Denmark, Finland, France, Germany, Hong Kong, Italy, Japan, Korea, Republic of, Norway, Russian Federation, Spain, Sweden, Taiwan, Turkey, Ukraine, United Kingdom
Akdeniz University

Recruiting

Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos

Infertility

Turkey
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

Carcinoma, Renal Cell

United States, Colombia, Canada, Australia, Finland, Japan, United Kingdom, Brazil, Chile, China, Croatia, Czechia, Denmark, France, Germany, Guatemala, Hungary, Ireland, Italy, Korea, Republic of, Malaysia, Mexico, Norway, Philippines, Polan... and more
Merck Sharp & Dohme LLC
Eisai Inc.

Active, not recruiting

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, vs Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)-China Extension Study

Carcinoma, Renal Cell

China
Novartis
Novartis Vaccines

Completed

Second Extension Study to Evaluate Safety and Tolerability of Influenza Vaccines in Adults and Elderly, and to Evaluate Immunogenicity and Concomitant Vaccination With Pneumococcal Vaccine in a Subgroup

Influenza

Poland
Federal University of Minas Gerais

Unknown

Transnasal Endoscopy in Obese Patients Are Candidates for Bariatric Surgery

Obesity | Bariatric Surgery Candidate

Brazil
UCB BIOSCIENCES GmbH

Completed

Study to Evaluate the Pharmacokinetics, Safety, Tolerability of Single Dose Lacosamide in Subjects With Renal Impairment Compared to Healthy Subjects

Healthy | Renal Impairment

Germany
UCB Pharma
Parexel

Completed

Pharmacokinetic (PK) Study in Japanese Non-epileptic Renal Impaired Patients

Healthy Subjects | Renal Impairments

Japan
AstraZeneca

Completed

Effect of a Pharmaceutical Intervention on the Level of Control of the Asthmatic Patient

Asthma

Spain
Merck Sharp & Dohme LLC

Recruiting

A Study of Belzutifan (MK-6482) in Combination With Palbociclib Versus Belzutifan Monotherapy in Participants With Advanced Renal Cell Carcinoma (MK-6482-024/LITESPARK-024)

Renal Cell Carcinoma

United States, Australia, Israel
University of Saskatchewan
Canadian Institutes of Health Research (CIHR)

Completed

Aquatic Exercise and Efficacy Enhancement to Decrease Fall Risk in Older Adults With Hip Osteoarthritis

Arthritis

Canada
Seoul National University Hospital

Unknown

Verify the Effectiveness rTMS Using MEG (rTMS)

Tinnitus

Korea, Republic of
Fuzhou General Hospital

Unknown

DC Vaccine Therapy Combined With Cytokine-Induced Killer Cell in Treating Patients With Renal Cell Carcinoma

Renal Cell Carcinoma

China
UCB Pharma

Terminated

Hormonal and Lipid Levels in Male Subjects After a Switch From Carbamazepine to Lacosamide (VICTOR)

Epilepsy, Partial

Austria, Germany, Spain
Northwestern University
Northwestern University Feinberg School of Medicine

Completed

Human Liver Explants for HIF-1 Alpha Analysis/Comparison (HIF HCC)

Liver Cancer

United States
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

Carcinoma, Renal Cell

Poland, Australia, Japan, United States, Korea, Republic of, Taiwan, China, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, Finland, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Malaysia, Mexico, Netherlands, New Zealand, Romani... and more
Mansoura University

Completed

Biliary Cannulation During Endoscopic Retrograde Cholangiopancreatography: Precut Versus Conventional Cannulation (ERCP)

Jaundice, Obstructive

Egypt
Seoul National University Hospital

Completed

Effects of Vasopressor on the Graft Blood Flow in TRAM

Blood Flow | Flap Necrosis | Flap Ischemia | Anastomotic Failure of Flap

Korea, Republic of
Federal University of São Paulo

Completed

Microcirculation After MAP Increase in Septic Shock Patients With Previous Hypertension

Septic Shock

Brazil
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

ICU Norepinephrine Load (ICU_NE_LOAD)

Circulatory Collapse and Shock

France
UCB Japan Co. Ltd.

Completed

An Open Label Study of L059 Intravenous (IV) in Japanese Epilepsy Subjects With Partial Onset Seizures

Epilepsy | Partial Onset Seizures

Japan
Gazi University
Hacettepe University; Cukurova University; Marmara University; Istanbul University and other collaborators

Unknown

Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children (ERTENIFABPICU)

Enteral Nutrition | Feeding Intolerance | Intestinal Fatty Acid Binding Protein

Germany
Boston Children's Hospital
Boston University; National Institute of Diabetes and Digestive and Kidney...

Completed

Nutrition Study for School Age Children

Obesity

United States
Ihsan GURSEL, PhD, Prof.
The Scientific and Technological Research Council of Turkey; MonitorCRO; Nobel...

Completed

Study of a Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Virus-like Particle (VLP) Vaccine (COVID-19)

Covid19

Turkey
Vifor Pharma, Inc.

Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

Hyperkalemia

United States, Israel
Davidzon, Guido, M.D.
Weston Havens Foundation

Recruiting

Imaging Synapses With [11C] UCB-J in the Human Brain

Schizophrenia

United States
Sanol GmbH

Completed

A Double-blind, Double-dummy, Parallel, Active-controlled, Randomized Trial to Evaluate Efficacy & Safety in Anemia Subjects

Iron Deficiency Anemia

China
University of Colorado, Denver
National Institutes of Health (NIH); American Diabetes Association

Completed

Influence of Endothelial Function on Central and Peripheral Causes Of Exercise Impairment in Type 2 Diabetes (InsITE)

Type 2 Diabetes

United States
Azienda Ospedaliero-Universitaria di Parma

Completed

Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 Diabetes

Type 2 Diabetes

Italy
University Hospital, Umeå

Recruiting

Multicenter Study for Diagnosis and Treatment of Perianal Abscesses

Perianal Abscess | Incontinence | Anal Fistulas

Sweden
Samsun University

Recruiting

Effects of Fluid Resuscitation on Capillary Refilling Time and Organ Functions in Septic Shock

Sepsis

Turkey
UCB Pharma

Completed

Safety Study of CDP7657 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus (SLE)

Immune System Diseases | Autoimmune Diseases | Lupus Erythematosus, Systemic | Skin and Connective Tissue Diseases | Connective Tissue Disease

Belgium, Bulgaria, Germany
Turkish Society of Anesthesiology and Reanimation

Not yet recruiting

High Flow Nasal Oxygen Therapy Undergoing Colonoscopy

Apnea | Hypoxia
Eastern Mediterranean University

Not yet recruiting

The Effects of the Instrumental Reminiscence Therapy

Elderly | Reminiscence Therapy

Cyprus
Chugai Pharmaceutical
Japan Lung Cancer Society

Completed

The Biomarker Exploratory Study in Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)

Non-small Cell Lung Cancer | Extensive Disease Small Cell Lung Cancer

Japan
şeyda öztürk

Completed

Headache in Undergraduate Students and Biopsychosocial Status

Migraine | Prevalence | Headache Disorders, Primary | Psychosocial Problem | Student

Turkey
Bulent Ecevit University

Unknown

For Easy, Fast and Comfortable Colonoscopy, Which Position (EFC_COLON)

Colonic Diseases, Functional | Endoscopy | Prone Position

Turkey
UCB Pharma

Completed

Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced Augmentation (AURORA)

Restless Legs Syndrome

Germany
Novartis Pharmaceuticals

Completed

Multicenter, Randomized, Open-label Study to Assess Whether Treatment With Mycophenolate Sodium (MPS) Allows Higher Dose Optimization Versus Mycophenolate Mofetil (MMF) Leading to a Dose Reduction of Tacrolimus. Maximiza Study. (MAXIMIZA)

Prophilaxis of Acute Rejection in Patients Receiving a Renal Allograft

Spain
Invibio Ltd
NGMedical GmbH

Recruiting

Study to Evaluate the Clinical and Radiographic Outcomes of the BEE® HA Cage for Anterior Cervical Discectomy and Fusion

Cervical Disc Degeneration

Germany

Search clinical trials for: hypoxia-inducible factor 2 alpha (HIF-2α, HIF-2 alpha)

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