Search clinical trials for: metformin

Total 2510 results

Aga Khan University
University of Karachi

Recruiting

Serum Biomarker Levels Improvement in Poly Cystic Ovarian Syndrome: Impact of Metformin Compared to Healthy Controls

Polycystic Ovary Syndrome | Insulin Resistance

Pakistan
State University of New York at Buffalo

Not yet recruiting

Metformin as an add-on or Monotherapy in Treatment of Aging People With Multiple Sclerosis (MS)

Multiple Sclerosis
Xuanwu Hospital, Beijing
Merck Serono Co., Ltd., China; Institute of Zoology, Chinese Academy of Sciences and other collaborators

Not yet recruiting

Pilot Study on Evaluating the Geroprotective Effect of Metformin (AGE-M)

Aging | Metformin

China
University of Massachusetts, Worcester

Not yet recruiting

Preventing T2DM After GDM With Immediate Postpartum Screening and Treatment

Type 2 Diabetes | Gestational Diabetes

United States
Amsterdam UMC
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Preeclampsia Intervention Netherlands (PI-NL)

Pre-Eclampsia | HELLP Syndrome | Pre-eclampsia or Eclampsia With Pre-existing Hypertension | HELLP | Pre-Eclampsia; Complicating Pregnancy | Pre-Eclampsia Onset Less Than 37 Weeks | Pre-Eclampsia as Antepartum Condition | Pre-Eclampsia; Affecting Fetus | HELLP Syndrome Complicating Pregnancy
Muhamed Ahmed Abdelmoaty Muhamed Alhagrasy

Not yet recruiting

Comparing the Effect of Metformin vs. Pep2dia as an Adjunct to Letrozole on Ovulation Induction and Pregnancy Outcomes in Overweight Women With PCOS

PCOS

Egypt
Zhujiang Hospital

Recruiting

Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD (HHTN)

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus

China
Ohio State University
Patient-Centered Outcomes Research Institute; The George Washington University...

Not yet recruiting

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes (DECIDE)

Pregnancy, High Risk | Gestational Diabetes Mellitus

United States
The University of Texas Health Science Center at...
Baptist Health Foundation of San Antonio

Recruiting

Prevention of Progression of Prediabetes, Obesity and CV Risk (Pre-DM)

Cardiovascular Diseases | Weight, Body | Pre-Diabetes

United States
Sichuan University

Not yet recruiting

Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinoma
King Saud University

Not yet recruiting

Effects of First-Line Oral Hypoglycemics in Bone Markers of Treatment Naïve Saudi Adults With Type 2 Diabetes

Osteoporosis | Diabetes Type 2
Boston Children's Hospital

Not yet recruiting

A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury

Hypoxic-Ischemic Encephalopathy | Infant Development | Neurodevelopment | HIE
Cairo University

Not yet recruiting

Efficacy and Safety of Lactoferrin in Heart Failure Patients

Heart Failure With Reduced Ejection Fraction
University of Alberta
Heart and Stroke Foundation of Canada

Not yet recruiting

Fish Oil, Metformin and Heart Health in PCOS

Cardiovascular Disease | PCOS | Cardiac Hypertrophy | Atherosclerotic Cardiovascular Disease | Atherosclerotic Plaque
Peking University First Hospital

Not yet recruiting

Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

Type 2 Diabetes
Incyte Corporation

Recruiting

A Study to Assess the Effect of Povorcitinib on Digoxin, Rosuvastatin, and Metformin Pharmacokinetics When Administered Orally to Healthy Adult Participants

Healthy Participants

United States
HighTide Biopharma Pty Ltd
Shenzhen HighTide Biopharmaceutical Ltd.

Recruiting

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

T2DM (Type 2 Diabetes Mellitus)

China
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer

Metastatic Breast Cancer

United States
Ming Lv

Not yet recruiting

Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE) (METTLE)

Dissecting Aneurysm of Cerebral Artery
Beni-Suef University

Not yet recruiting

Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome

Polycystic Ovary

Egypt
Shandong Suncadia Medicine Co., Ltd.

Not yet recruiting

Efficacy and Safety of HRS-7535 Tablets in T2DM Subjects Poorly Controlled With Metformin and SGLT2i.

Type 2 Diabetes
Mayo Clinic

Recruiting

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Malignant Brain Neoplasm

United States
Marius Henriksen

Recruiting

Metformin Treatment of Patients With Hand Osteoarthritis (METRO)

Hand Osteoarthritis

Denmark
Peking Union Medical College Hospital

Not yet recruiting

Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer

Cervical Cancer | Hypoxia | Radiotherapy | Metformin | PET/CT
Chengdu Brilliant Pharmaceutical Co., Ltd.

Not yet recruiting

Efficacy and Safety of Semaglutide Injection in Subjects With Type 2 Diabetes

Type 2 Diabetes Mellitus
Hangzhou Sciwind Biosciences Co., Ltd.

Recruiting

A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or Digoxin

Healthy Volunteers

China
Ziauddin University

Not yet recruiting

Metformin Repurposing in Oral Submucous Fibrosis: Unveiling In Vitro Signaling Pathways, Progressing to Clinical Trial (MROSF)

Oral Submucous Fibrosis

Pakistan
Aalborg University Hospital

Recruiting

The Effect of Adherence to Oral Semaglutide on Glycaemic Control in People With Type 2 Diabetes Treated With Metformin (DIACRON)

Diabetes Mellitus, Type 2

Denmark
AstraZeneca

Recruiting

Efficacy of FDC Regimen of Dapagliflozin/Metformin Compared to Co-administered Dual Therapy on Glycemic Control, Satisfaction and Adherence in Chinese Patients With T2DM

Type 2 Diabetes Mellitus (T2DM)

China
Assiut University

Not yet recruiting

Vitamin D With Omega-3 or Metformin in Osteoarthritis

Osteoarthritis
Shanghai 10th People's Hospital

Recruiting

PCOS Immune Function Predicts Metformin Efficacy

Polycystic Ovary Syndrome | Immune Function | Metformin

China
Shanghai 10th People's Hospital

Recruiting

PCOS Patients Immune Status Evaluation

Immune Function | Metformin | Polycystic Ovary Syndrom

China
Novo Nordisk A/S

Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin (REIMAGINE 3)

Type 2 Diabetes

United States, Japan, Serbia, China, South Africa, Slovakia
Imperial College London

Not yet recruiting

The GAPSID Study - How GLP-1 Analogues Prevent Steroid-Induced Diabetes

Steroid-Induced Diabetes | Steroid Induced Hyperglycemia

United Kingdom
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)

Type 2 Diabetes

United States, Argentina, United Kingdom, Puerto Rico
University of Illinois at Chicago
Emily Hanners; Dulal Bhaumik; Avisek Datta; Peggy Choye; Hailey Soni; Annesti Elmasri; Julie Jun and other collaborators

Not yet recruiting

Effect of Continuing Versus Holding Metformin During Hospitalizations.

Diabetes Mellitus, Type 2

United States
Oregon Health and Science University

Recruiting

Metformin Use in Patients Undergoing Total Joint Replacement Surgery

Hyperglycemia

United States
Johns Hopkins University
Baylor College of Medicine; National Heart, Lung, and Blood Institute (NHLBI); Temple University

Not yet recruiting

Metformin IN Asthma for Overweight and Obese Individuals (MINA)

Asthma | Overweight and Obesity | Asthma Chronic
Eli Lilly and Company

Recruiting

Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)

Diabetes Mellitus, Type 2

United States, Canada, Mexico, Argentina, Puerto Rico
Beijing Dongfang Biotech Co., Ltd.

Not yet recruiting

A Phase 3 Study to Evaluate the Efficacy of JY09 Compared With Dulaglutide in Combination Therapy Diabetes Mellitus Type 2 Patients With Metformin

Type2 Diabetes Mellitus

China
Ping Li,MD

Not yet recruiting

Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome | Non-Alcoholic Fatty Liver Disease
Bangabandhu Sheikh Mujib Medical University, Dhaka...

Recruiting

Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.

Acne Vulgaris

Bangladesh
Bio-innova Co., Ltd

Not yet recruiting

Vildagliptin and Metformin Tablets 50/1000 mg Relative to GALVUS MET (50mg/1000 mg) Tablets

Healthy Subjects
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

Type 2 Diabetes (Adult Onset)

United States
University Hospital "Sestre Milosrdnice"
University of Zagreb School of Medicine

Not yet recruiting

The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients

Overweight | Type 2 Diabetes | Disordered Eating Behaviors

Croatia
International Bio service

Not yet recruiting

The Bioequivalence Study of Fixed-dose Combination of Vildagliptin and Metformin HCI 50/1000 mg FCT Under Fed Conditions

Healthy Volunteer
Bio-innova Co., Ltd

Not yet recruiting

Sitagliptin and Metformin Hydrochloride Tablets 50 mg/500 mg Relative to Originator

Healthy Subjects
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.

Not yet recruiting

Phase 3 Study of TG103 Injection Combined With Metformin in Treatment of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus

China
Bio-innova Co., Ltd

Not yet recruiting

Sitagliptin and Metformin Hydrochloride Tablets 50 mg/1000 mg Relative to Originator

Healthy Subjects
Mostafa Bahaa

Recruiting

Metformin Safety and Efficacy in Osteoarthritis.

Osteo Arthritis Knee

Egypt

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