Search clinical trials for: 1 mg/kg single infusion of F598

Total 2148 results

Assistance Publique - Hôpitaux de Paris

Recruiting

Efficacy of 24 Month of Bezafibrate in Primary Sclerosing Cholangitis With Persistent Cholestasis Despite Ursodeoxycholic Acid Therapy (BEZASCLER)

Primary Sclerosing Cholangitis | Cholestasis

France
Yuhan Corporation

Completed

Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of YH4808 After Oral Administration in Healthy Male Subjects

Healthy

Korea, Republic of
Vectura, Inc.
Syneos Health

Terminated

Study to Compare the Pharmacokinetics and Pharmacodynamics of ASA Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Adult Subjects With Obstructive or Restrictive Pulmonary Function

Obstructive Pulmonary Function | Restrictive Pulmonary Function

United States
Boehringer Ingelheim
Eli Lilly and Company

Completed

Relative Bioavailability of 2 Fixed Dose Combinations of Empagliflozin/Metformin Extended Release (XR) Compared With Single Tablets

Healthy

United States
University Hospital, Basel, Switzerland

Completed

The Role of Endogenous GLP-1 (Glycolipoprotein) in Regulating Glucose Stimulated Brain Activity

Exploratory Behavior

Switzerland
NYU Langone Health

Active, not recruiting

Nivolumab Combined With BMS-986253 in HCC Patients

Hepatocellular Carcinoma

United States
Merck Sharp & Dohme LLC
Pfizer

Completed

Study of Safety and Efficacy Of Ertugliflozin (PF-04971729, MK-8835) In Participants With Type 2 Diabetes And Hypertension (MK-8835-042)

Hypertension | Diabetes Mellitus, Type 2
Cairo University

Completed

Multimodal Opioid-free Anesthesia Versus Opioid-based Anesthesia for Patients Undergoing Cardiac Valve Surgeries: RCT

Anesthesia

Egypt
Aziende Chimiche Riunite Angelini Francesco S.p.A
Zak-Pharma Dienstleistung Ges.m.b.H.

Completed

Benzydamine in Sore Throat Pain Relief (BePaiR Study) (BePaiR)

Acute Sore Throat

Hungary, Poland, Russian Federation
Peking University

Not yet recruiting

Esketamine Adjuvant Therapy for Patients With Chronic Visceral Pain Comorbid Major Depressive Disorder

Major Depressive Disorder | Chronic Visceral Pain
AstraZeneca

Terminated

GALLANT 7 Tesaglitazar Add-on to Sulphonylurea

Type 2 Diabetes

France, Korea, Republic of, South Africa, Spain, United Kingdom, Vietnam, Norway, Israel, Philippines, Australia
Rigshospitalet, Denmark

Completed

A Comparison of Rocuronium 0.6 mg/kg and Remifentanil 2 µg/kg in Elderly Patients Over 80 Years

Anesthesia | Intubation Complication | Neuromuscular Blockade

Denmark
Laboratorios Silanes S.A. de C.V.

Recruiting

Oral Combination of Glimepiride/Vildagliptin/Metformin in Patients With T2D and Dual Treatment Failure

Type 2 Diabetes

Mexico
Actavis Inc.

Completed

A Relative Bioavailability Study of Gabapentin Tablets 800 mg Under Fasting Conditions

Healthy

United States
Actavis Inc.

Completed

A Relative Bioavailability Study of Gabapentin Tablets 800 mg Under Non-fasting Conditions

Healthy

United States
Janssen Research & Development, LLC

Completed

A Bioequivalence Study of the Fixed Dose Combination Tablets of Canagliflozin and Metformin Extended Release (XR) With Respect to the Individual Components in Healthy Fed Participants

Healthy

United States
Cairo University

Unknown

Phenylephrine Infusion in Cesarean Delivery

Cesarean Section Complications | Spinal Anesthesia

Egypt
Amgen

Completed

Safety Study of AMG 386 to Treat HER2-positive Locally Recurrent or Metastatic Breast Cancer

Cancer | Breast Cancer | Breast Neoplasms | Metastatic Cancer | Breast Tumors | Solid Tumors | Oncology | Tumors | Metastases | Locally Recurrent and Metastatic Breast Cancer

United States, Belgium, France
Midnight Pharma, LLC

Completed

Study to Evaluate the Relative Abuse Potential of Almorexant in Recreational Drug Users

Abuse Potential Study
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Active, not recruiting

A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer

Bladder Cancer | Urothelial Carcinoma | Metastatic Bladder Cancer

United States
Rigshospitalet, Denmark

Completed

Neuromuscular Blocking Agents in the Elderly

Elective Surgery

Denmark
Hangzhou Cancer Hospital

Unknown

Endostatin in Combination With Oxaliplatin and Radiotherapy in Esophageal Cancer Patients.

Esophageal Cancer | Endostatin

China
Morphotek

Terminated

An Efficacy and Safety Study of MORAb-003 in Platinum-Resistant or Refractory Relapsed Ovarian Cancer (FAR-122)

Ovarian Cancer

Canada, United States, Netherlands, Spain, Belgium, Australia
H. Lundbeck A/S

Completed

Pharmacokinetic Properties of Vortioxetine in Healthy Young Chinese Men and Women

Pharmacokinetics

China
GlaxoSmithKline

Completed

Evaluate Safety, Tolerability, and Pharmacokinetics of Single and Repeat IV Doses

Infections, Respiratory Tract

Australia
UCB Japan Co. Ltd.

Completed

Multiple-dose Study of Levetiracetam Injection in Japanese and Caucasian Healthy Males

Healthy Volunteers

Japan
SUNHO（China）BioPharmaceutical CO., Ltd.

Recruiting

IAH0968 in Combination With GC for the Treatment of HER2-Positive Unresectable Advanced/Metastatic Malignant Tumors

HER2 Gene Mutation

China
All India Institute of Medical Sciences, New Delhi

Completed

Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage

Tuberculosis | Drug Induced Hepatotoxicity

India
Baylor College of Medicine

Completed

Dexmedetomidine in Pediatric Tonsillectomy

Post Operative Analgesia | Pediatric Adenotonsillectomy

United States
Cairo University

Completed

Three Protocols for Phenylephrine Administration in Cesarean Delivery

Cesarean Section Complications | Spinal Anesthesia

Egypt
Teva Pharmaceuticals USA

Completed

Granisetron 1 mg Tablets Under Fasting Conditions

Healthy

Canada
Oyster Point Pharma, Inc.

Completed

Evaluating Relative Bioavailability of OC-01 (Varenicline) Nasal Spray as Compared to Orally Administered Varenicline

Healthy Subjects

United States
Merck Sharp & Dohme LLC

Recruiting

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Invasive Fungal Infection

Israel, United States, Belgium, Greece, Peru, Poland, Mexico, Russian Federation
Harokopio University
National and Kapodistrian University of Athens; University of Peloponnese

Unknown

Oleocanthal Rich Olive Oil Acute Effects on Hyperglycemia and Platelet Activation in T2DM

Inflammation | Oxidative Stress | Postprandial Hyperglycemia | Diabetes Mellitus, Adult-Onset | Platelet Dysfunction | Lipidemia

Greece
Yonsei University

Completed

Comparison of the Effect of Propacetamol, Ibuprofen or Their Combination on Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children

Inguinal Hernia

Korea, Republic of
ViiV Healthcare

Completed

Low-dose Fostemsavir Extended Release Relative Bioavailability Study

HIV Infections

United States
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
GlaxoSmithKline

Completed

A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)

Diabetes Mellitus, Type 2

Japan
AO GENERIUM

Withdrawn

Efficacy and Safety of GNR-038 vs Berinert® in Patients With Hereditary Angioedema

Hereditary Angioedema

Russian Federation
University of Rome Tor Vergata
Merck Sharp & Dohme LLC

Completed

Glucagon-like Peptide 1 (GLP-1) and Endothelial Dysfunction in Metabolic Syndrome

Metabolic Syndrome

Italy
Mirjana Cihoric

Completed

Preoperative High-dose Dexamethasone and Emergency Laparotomy

Sepsis | Inflammatory Response | Pathophysiology | Intestinal Obstruction and Ileus | Perforated Viscus

Denmark
GlaxoSmithKline
Duke Clinical Research Institute

Completed

Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Diabetes Mellitus

United States, Argentina, Germany, Poland, Russian Federation, Spain, Taiwan, Czechia, Hungary, Italy, Ukraine, Belgium, Netherlands, South Africa, Sweden, Thailand, Korea, Republic of, Mexico, Bulgaria, Hong Kong, Peru, Philippines, Gree... and more
Stichting Hemato-Oncologie voor Volwassenen Nederland
Danish Lymphoma Group

Recruiting

Tislelizumab, Gemcitabine and Cisplatin for R/R Hodgkin Lymphoma Followed by Tislelizumab Consolidation in Patients in Metabolic Complete Remission (HOVON164HL)

Hodgkin Lymphoma

Netherlands, Belgium, Denmark
Udayana University

Completed

Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy (PRO-Ketamine)

Inflammation | General Anesthesia | Laparotomy

Indonesia
Eli Lilly and Company
Locemia Solutions ULC

Completed

Safety and Efficacy of a Novel Glucagon Formulation in Type 1 Diabetic Patients Following Insulin-induced Hypoglycemia (AMG102)

Hypoglycemia

Canada
Trius Therapeutics LLC

Completed

A Pharmacokinetics and Safety Study in Subjects With Renal Impairment

Renal Impairment

United States
Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

Gemcitabine-based Induction Chemotherapy Combined With Concurrent Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Swiss Federal Institute of Technology

Completed

The Optimization of Bioavailability From Iron Supplements: Study 2

Anemia | Iron Deficiency Anemia | Iron Deficiency

Switzerland
Zhejiang Cancer Hospital

Unknown

Endostar Combination With Chemotherapy for the Metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Portola Pharmaceuticals

Completed

A Healthy Volunteer PK/PD, Safety and Tolerability Study of Second Generation Andexanet Alfa

Bleeding

United States

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